Clinical trials: Pain Relief
Pain
Effects of Anticipation of Pain Relief on Brain Mechanisms
This study will use brain imaging technology to examine chemical systems in the brain that suppress pain and stress when an individual has an expectation of pain relief.
- Trial name
- NCT00200876
- Testing
- Hypertonic saline, Isotonic saline
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Postoperative Pain
The Effect of Intravenous Lidocaine on Pain After Thyroidectomy
This prospective randomized study aims to evaluate the effectiveness of intravenous lidocaine injection on the relief of pain in patients undergoing thyroidectomy.
- Trial name
- NCT01608360
- Testing
- Intravenous lidocaine injection, Intravenous normal saline injection
- Where
- South Korea
- Volunteers
- 56 people
- Sponsor
- Chung-Ang University Hospital
Lumbar Spine Surgery
Safety and Efficacy of DepoDur in Lumbar Spine Surgery Patients
The purpose of the study is to help determine the appropriate dose of DepoDur for use in spinal surgery. The study will also assess the safety of this drug in this patient population.
- Trial name
- DepoDur (NCT00335517)
- Testing
- DepoDur
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- University of Rochester
Dysmenorrhea
Intravenous Tramadol Versus Intravenous Paracetamol in Patients With Dysmenorrhea
Patients presented with primary dysmenorrhea composed the study population. One gram paracetamol and 100 mg tramadol in 100 ml saline with a slow infusion were compared in ceasing dysmenorrhea in the emergency department
- Trial name
- NCT03509740
- Testing
- tramadol, paracetamol
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Cairo University
Knee Osteoarthritis
Radio-frequency Ablation in Knee Osteoarthritis by Three Needles Technique
The study is designed to evaluate and compare the efficacy of three needles approach as a new technique in radiofrequency neurotomy of genicular nerve versus the traditional single needle approach as a treatment of advanced knee…
- Trial name
- NCT03613610
- Testing
- Radio-frequency ablation of genicular nerves
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Alaa Fouli Gaber Ebrahim
Pain, Chronic
Empowered Relief Delivered by Nurses
This study will investigate effects of a psychoeducation pain management skills intervention on adults with persistent pain by training a cohort of American Society for Pain Management Nursing (ASPMN) nurses to deliver and it…
- Trial name
- ERA (NCT05934435)
- Testing
- Empowered Relief
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Washington State University
Post Operative Pain, Post-Op Complication
Effect of Occlusal Reduction on Relief of Pain and Sensitivity to Percussion in Patients With Irreversible Pulpitis
One of the most important aspects of endodontic practice is to abate pain during and post root canal treatment. An endodontist by all means should provide a painless endodontic treatment to their patients.
- Trial name
- NCT05306535
- Testing
- Occlusal reduction
- Where
- Pakistan
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Altamash Institute of Dental Medicine
Diabetic Neuropathy, Neuropathic Pain
Extended-release Pregabalin for the Treatment of Neuropathic Pain in Patients With Diabetic Peripheral Neuropathy and Postherpetic Neuralgia
Extended-release Pregabalin for the Treatment of Neuropathic Pain in Patients With Diabetic Peripheral Neuropathy and Postherpetic Neuralgia
- Conditions
- Diabetic Neuropathy, Neuropathic Pain, Neuralgia, Postherpetic
- Trial name
- PRISE (NCT07712913)
- Testing
- Experimental: Pregabalin XR, Comparator: Dorene Tabs
- Where
- 15 sites in Brazil
- Volunteers
- 348 people
- Sponsor
- Brainfarma Industria Química e Farmacêutica S/A
Diabetic Peripheral Neuropathic Pain
Diabetic Neuropathic Pain Relief, 6 Weeks Dosage Sublingual Water-soluble CBD/PEA
The purpose of the study is to evaluate whether the DIA/NPR-6 is a better pain reliever in patients with diabetic neuropathic pain of the feet compared to placebo.
- Trial name
- NCT05766969
- Testing
- CBD/PEA
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Pure Green Pharmaceuticals Inc.
Music Therapy
Music and Symptom Relief in Radiotherapy Patient
This randomized controlled study aims to evaluate the effects of music therapy administered during radiotherapy sessions on pain, stress, and anxiety levels in cancer patients.
- Trial name
- MUSİC (NCT06993441)
- Testing
- Experimantal group, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ege University
Tonsillitis
Effectiveness of Tonsil Fossa Closure in Pain Relief After Tonsillectomy in Children
Objective: Postoperative pain is the main complaint in children undergoing tonsillectomy. An inexpensive method and with few evidence in the literature on effectiveness in reducing pain is the closure of the tonsillar fossa by…
- Trial name
- NCT02676583
- Testing
- Tonsillectomy
- Where
- Brazil
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Marco Aurelio Fornazieri
Peripheral Artery Disease, Severe Intermittent Claudication
Autologous CD34+ Stem Cell Injection for Severe Intermittent Claudication (Leg Pain)
The goal of the study is to determine the safety and possible effectiveness of various doses of autologous (one's own) stem cells, delivered with a needle into the regions of the leg with poor blood flow in patients with blocked…
- Trial name
- NCT00311805
- Testing
- Autologous Stem Cells (CD34+)
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- Losordo, Douglas, M.D.
Sacral Erector Spinae, Penile And Caudal Block For Pain Relief After Hypospadius Surgery
Sacral Erector Spinae,Penile and Caudal Block for Pain Relief After Hypospadias Surgery
Caudal anaesthesia is recommended for most surgical procedures of the lower part of the body, mainly below the umbilicus, including inguinal hernia repair, urinary and digestive tract surgery and orthopaedic procedures on the…
- Trial name
- NCT05307653
- Testing
- Penile block, Erector spinea plain block, Caudal block
- Where
- Egypt
- Volunteers
- 132 people
- Sponsor
- Tanta University
Chronic Pelvic Pain
Empowered Relief for Chronic Pelvic Pain
Primary Aim To determine if the addition of empowered relief therapy to standard treatment is superior to standard treatment alone in patients with chronic pelvic pain as measured by pain interference in patients with chronic…
- Trial name
- ER_for_CPP (NCT07812857)
- Testing
- Empowered Relief (ER) Therapy
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Chicago
Stable Angina
Finding the Invasive Haemodynamic Threshold for Symptom Relief in Stable Angina
ORBITA-FIRE is a randomised, double-blinded, placebo controlled experimental study that will identify the fractional flow reserve (FFR) and non-hyperemic pressure ratio (NHPR) thresholds that correlate with symptoms of angina for…
- Trial name
- ORBITA-FIRE (NCT05459051)
- Testing
- Rest-angina physiological assessment, Exercise-angina physiological assessment
- Where
- 6 sites in United Kingdom
- Volunteers
- 58 people
- Sponsor
- Imperial College London
Shoulder Pain
Anatomically-Guided Electroacupuncture Combined With Cupping for Shoulder Pain
This study compares two acupuncture-based treatments for shoulder pain. Adults with shoulder pain will be randomly assigned to one of two groups.
- Trial name
- NCT07798531
- Testing
- Anatomically-guided electroacupuncture, Moving cupping therapy, Classical electroacupuncture
- Where
- Vietnam
- Volunteers
- 70 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Neck Pain Musculoskeletal, Neck Pain Treatment
Validating a Clinical Prediction Rule to Guide Manual Therapy and Exercise for Neck Pain Relief
Neck pain is a common issue that can lead to long-term disability and lost work time for many individuals. Despite numerous studies, finding effective treatment strategies has been challenging.
- Conditions
- Neck Pain Musculoskeletal, Neck Pain Treatment, Cervicalgia
- Trial name
- NCT06906107
- Testing
- Cervical Manipulation, Exercise, Mobilization
- Where
- 4 sites in United States
- Volunteers
- 160 people
- Sponsor
- Baylor University
Pain
Local Infiltration Analgesia After Abdominal Hysterectomy
The aim of the study is to evaluate traditional analgesic therapy after abdominal hysterectomy with single infiltration of local anesthetics in the surgical area at the end of surgery.
- Trial name
- LIA (NCT01782781)
- Testing
- ropivacaine, ketorelac and epinephrine
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Göteborg University
Laparoscopic Cholecystectomy Surgery, Analgeisa
Pain Relief Following Laparoscopic Cholecystectomy While Comparing Intra Abdominal Versus Sub Cutaneous Local Anesthetic Administration
Laparoscopic cholecystectomy involves removal of gallbladder through small incision ports resulting in faster recovery. Small incisions are less painful and hence local anesthesis administered can be effective for pain…
- Conditions
- Laparoscopic Cholecystectomy Surgery, Analgeisa, Local Anesthetic Infiltration
- Trial name
- NCT07409688
- Testing
- Intraoperitoneal local anesthetic administration, Sub cutaneous administration of local anesthetic
- Where
- Pakistan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Rawalpindi Medical College
Gallstones, Gallstone Attack
The Pro-Chol Study
This prospective clinical cohort study will include patients with gallstones and abdominal pain scheduled for surgery (laparoscopic cholecystectomy).
- Conditions
- Gallstones, Gallstone Attack, Uncomplicated Cholelithiasis, Cholecystolithiasis
- Trial name
- ProChol (NCT07245108)
- Testing
- Laparoscopic cholecystectomy
- Where
- 7 sites in Denmark
- Volunteers
- 800 people
- Sponsor
- Nordsjaellands Hospital