Clinical trials: Pain Score
Colonoscopy Pain
Pre-procedural Risk Score-Based Endoscopist Assignment for Pain Reduction in Unsedated Colonoscopy
This multicenter randomized controlled trial evaluates whether a pre-procedural risk score-based endoscopist assignment strategy reduces intraprocedural pain in high-risk patients undergoing unsedated colonoscopy.
- Trial name
- NCT07713953
- Testing
- Risk Score-Based Endoscopist Assignment
- Where
- China
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Ningbo No. 1 Hospital
Post-herpetic Neuralgia
Dose Response Study of EMA401 in Patients With Post-herpetic Neuralgia (PHN)
This study was designed to characterize dose response, and evaluate safety and efficacy of three different doses of EMA401 compared to placebo in patients with post-herpetic neuralgia (PHN).
- Trial name
- EMPHENE (NCT03094195)
- Testing
- EMA401
- Where
- 58 sites in Australia, Austria and 17 more
- Volunteers
- 130 people
- Sponsor
- Novartis Pharmaceuticals
Pain
Binaural Music Study
To evaluate client experience relating to mammography and pain scores for patients attending for annual surveillance mammography with a family history of breast cancer.
- Trial name
- NCT05240196
- Testing
- music
- Where
- United Kingdom
- Volunteers
- 57 people
- Sponsor
- Tameside General Hospital
Emergency Medicine, Artificial Intelligence (AI)
Diagnostic Accuracy of GPT-4o and Claude for HEART Score Calculation in Chest Pain
This prospective observational diagnostic accuracy study evaluates whether large language models (LLMs) - GPT-4o (OpenAI, gpt-4o-2024-11-20) and Claude (Anthropic, claude-sonnet-4-6) - can accurately calculate HEART scores from…
- Conditions
- Emergency Medicine, Artificial Intelligence (AI), Artificial Intelligence (AI) in Diagnosis, Chest Pain Rule Out Myocardial Infarction
- Trial name
- LLM-HEART (NCT07626060)
- Testing
- GPT-4o HEART Score Calculator, Claude HEART Score Calculator, Three-Expert Consensus HEART Score
- Where
- Turkey (Türkiye)
- Volunteers
- 690 people
- Sponsor
- Marmara University Pendik Training and Research Hospital
CRPS (Complex Regional Pain Syndromes)
Forward Looking InfraRed Imaging and Severity Score in Complex Regional Pain Syndrome
The goal of this interventional study is to explore the use of InfraRed (FLIR) imaging in determining pain intensity and severity in newly diagnosed complex regional pain syndrome patients.
- Trial name
- FLIR (NCT05852210)
- Testing
- Infrared Imaging
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Hospital for Special Surgery, New York
Pain Relief in Post Operative Patient
Comparison of Pain ReliefofBupivacaineWith Dexmedetomidine and Bupivacaine Alone in TransversusAbdominisPlane Block For Postoperative Anelgesia in Patients Undergoing Abdominal Surgeries
Postoperative pain related to abdominal surgeries poses significant burden on the healthcare system, in terms of increased use of different analgesics, delayed ambulation, pulmonary complications, DVT, and prolonged hospital…
- Trial name
- NCT05244252
- Testing
- dexmeditomidine and bupivacaine, Bupivacaine
- Where
- Pakistan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Sheikh Zayed Medical College
Postoperative Pain
Effect of a Sciatic Block (SNB) Combined With a Continuous Femoral Block (CFNB) on Pain Scores After Knee Arthroplasty
The purpose of this study is to determine if the addition of a sciatic nerve block (SNB) to a continuous femoral nerve block (CFNB) improves post-operative analgesia after knee arthroplasty.
- Trial name
- NCT01337115
- Testing
- SNB plus CFNB, CFNB
- Where
- Portugal
- Volunteers
- 50 people
- Sponsor
- Centro Hospitalar do Porto
Osteoarthritis, Knee
Does Electrocautery Increase Postoperative Pain in Primary Total Knee Arthroplasty
Total knee arthroplasty (TKA) is a successful treatment for end-stage osteoarthritis of the knee. The main advantages of TKA are to relieve the pain of the knee, improve the knee function, restore lower limb alignment, and…
- Trial name
- NCT06239038
- Testing
- total knee arthroplasty
- Where
- Thailand
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Police General Hospital, Thailand
Coronary Artery Disease, Angina Pectoris
Clinician Utilization of Corus CAD (or ASGES) in Primary Care Provider Decision Making
This retrospective study will investigate clinician behavior in diagnosing patients with possible obstructive coronary artery disease who received a Corus CAD (Age/Sex/Gene Expression score - ASGES) result compared to patients…
- Conditions
- Coronary Artery Disease, Angina Pectoris, Chest Pain, Cardiovascular Diseases
- Trial name
- CU-PCP (NCT02158754)
- Testing
- Corus CAD (ASGES)
- Where
- 9 sites in United States
- Sponsor
- CardioDx
Atrial Fibrillation
High Power vs Standard Power RF Ablation of Atrial Fibrillation in Conscious Patients
High RF energy ablation of atrial fibrillation is fast, safe, less painful and effective procedure.
- Trial name
- HPvSP-AF (NCT04250181)
- Testing
- RF ablation of atrial fibrillation
- Where
- Poland
- Volunteers
- 30 people
- Sponsor
- Medical University of Lublin
Neck, Shoulder and Arm Syndrome
Neck-shoulder Pain. Large Scale Prospective Cohort Study
The aim of this study is to determine and statistically justify the correlation between shoulder girdle injuries and the development of neck-shoulder pain syndrome.
- Trial name
- NSP (NCT04366570)
- Testing
- clinical assessment of the shoulder and the cervical spine includes stress guideline tests
- Volunteers
- 1,402 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Onset and Duration of Sensory and Motor Block of Femoral Nerve,, Visual Analogue Pain Scores,
Perineural Dexmedetomidine and Femoral Nerve Block
The duration of sensory block after single dose of long acting local anesthetics is not sufficient to avoid the postoperative use of opioids.
- Conditions
- Onset and Duration of Sensory and Motor Block of Femoral Nerve,, Visual Analogue Pain Scores,, Time to First Request of Rescue Analgesics,, Total Morphine Consumption in 24 Hours
- Trial name
- NCT01964040
- Testing
- peri-neural dexmedetomidine as adjuvant to bupivacaine in femoral nerve block
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Cairo University
Pilonidal Sinus, Wound Healing
ENVELOP: Wound Care Following Pilonidal Sinus Surgery
This is a single-blinded, multicentre, prospective randomised controlled trial (RCT) comparing post-operative and patient-reported outcomes for patients undergoing application of negative-pressure wound therapy (NPWT) after sinus…
- Trial name
- ENVELOP (NCT06647290)
- Testing
- Negative Pressure Wound Therapy, Standard wound care
- Where
- 10 sites in Ireland
- Volunteers
- 200 people
- Sponsor
- Royal College of Surgeons, Ireland
for Post-operative Pain Relief in Spine Surgeries
Low Dose Perioperative Ketamine Infusion and it's Effect on Postoperative Pain Score, Sedation Score and Narcotic Consumption in Patients Undergoing Spine Surgery: A Prospective Randomized Double Blind Control Trial.
Low dose perioperative ketamine infusion and it's effect on postoperative pain score, sedation score and narcotic consumption in patients undergoing spine surgery: A prospective randomized double blind control trial.
- Trial name
- NCT04259476
- Testing
- Ketamine Hydrochloride
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Services Institute of Medical Sciences, Pakistan
Acute Coronary Syndrome, Chest Pain
PARA-HEART Pilot Implementation
Approximately 8-10 million patients complaining of chest pain present to an Emergency Department (ED) annually in the United States.
- Trial name
- PARA-HEART (NCT02709135)
- Where
- United States
- Volunteers
- 511 people
- Sponsor
- Wake Forest University Health Sciences
Healthy
A Comparative Clinical Study to Assess Pain Score and Wound Healing Following Fractional Ablation With a DFG Laser and CO2 Laser
This research study aims assess whether the Difference Frequency Generation (DFG) laser could be a better alternative to the CO2 laser in terms of reduced side effects and patient downtime.
- Trial name
- NCT06295471
- Testing
- DFG Laser, CO2 Laser, Optical coherence tomography (OCT)
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Tracheal Intubation Morbidity, Pain
Prediction of Hemodynamic Response to Intubation by ANI Variation During Standardized Stimulation
The objective : to investigate a correlation between ANI following a standardized nociceptive stimulus and hemodynamic or somatic reactions during orotracheal intubation. Piloted study.
- Trial name
- ANI_LARYNGO (NCT04354311)
- Testing
- ANI
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Lille
Chest Pain, Coronary Artery Disease
A Registry to Evaluate Patterns of Care Associated With the Use of Corus CAD (or ASGES) in Primary Care Settings
The PRESET Registry--A Registry to Evaluate Patterns of Care Associated With the Use of Corus CAD (Age/Sex/Gene Expression score - ASGES) in Real World Clinical Care Settings (PRESET)--was designed as an observational…
- Conditions
- Chest Pain, Coronary Artery Disease, Cardiovascular Diseases, Coronary Heart Disease
- Trial name
- PRESET (NCT01677156)
- Testing
- CORUS CAD (ASGES)
- Where
- 13 sites in United States
- Volunteers
- 713 people, healthy volunteers welcome
- Sponsor
- CardioDx
Postoperative Recovery, Abdominal Pain
Comparison of the Quality of Recovery After Cesarean Section Surgery
Inadequate pain control after cesarean section surgery causes postpartum depression, persistent pain and delayed mother-infant bonding.
- Conditions
- Postoperative Recovery, Abdominal Pain, Cesarean Section
- Trial name
- NCT05999981
- Testing
- Transversalis Fascia Plane Block, Transversus Abdominis Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Muğla Sıtkı Koçman University
Surgical Incision, Gynecologic Surgery
Postoperative Pain Score of Laparoscopic Gynecological Surgeries
In this study, it was aimed to compare the embryonic route, the umbilicus, and the sub-umbilicus incision in terms of postoperative pain scoring.
- Conditions
- Surgical Incision, Gynecologic Surgery, Postoperative Pain
- Trial name
- NCT05296928
- Testing
- laparoscopic incision
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Baskent University