Clinical trials: Pain Severity
Healthy
A Study to Characterize the Abuse Liability of ALO-02 in Healthy, Non-Dependent, Recreational Opioid Abusers
The main purpose of this study is to determine if oxycodone and naltrexone combination capsules (ALO-02) have the potential to be abused.
- Trial name
- NCT01746901
- Testing
- intact ALO-02 60 mg/7.2 mg, crushed ALO-02 60 mg/7.2 mg, crushed oxycodone IR 60 mg
- Where
- Canada
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Pfizer
Perineal Laceration Repair
Comparison of Absorbable Sutures in Perineal Laceration Repair
The purpose of this study is to determine the difference in pain scales between absorbable suture types for second-degree perineal laceration repair.
- Trial name
- NCT00223119
- Testing
- Absorbable Sutures
- Where
- United States
- Sponsor
- Medtronic - MITG
Chronic Low Back Pain
ReActiv8 for Chronic Low Back Pain (PMCF)
The purpose of this Clinical Study is to investigate the effect of electrical stimulation for chronic low back pain.
- Trial name
- ReActiv8-A (NCT01985230)
- Testing
- ReActiv8 Implantable Stimulation System implanted and activated.
- Where
- 15 sites in Australia, Belgium and 1 more
- Volunteers
- 96 people
- Sponsor
- Mainstay Medical
Bone Metastases
ExAblate Conformal Bone System Treatment of Metastatic Bone Tumors for the Palliation of Pain
A study to evaluate the safety and initial effectiveness of the ExAblate 2100 Conformal Bone System in the treatment of pain resulting from metastatic bone tumors.
- Trial name
- NCT00981578
- Testing
- ExAblate 2100
- Where
- 5 sites in United States
- Volunteers
- 37 people
- Sponsor
- InSightec
Chronic Pain
OTR Tablet 10 mg Fasted-state Bioequivalence Study
This is an open-label, single Dose, randomised, cross-over study to confirm the bioequivalence (BE) of OTR tablet 10 mg and OXYCONTIN tablet 10 mg in a fasted state in Chinese subjects with chronic pain
- Trial name
- NCT03403504
- Testing
- Oxycodone Tamper Resistant, OXYCONTIN®
- Where
- China
- Volunteers
- 24 people
- Sponsor
- Mundipharma (China) Pharmaceutical Co. Ltd
Low Back Pain
Comparison of BTDS (Buprenorphine Transdermal System) and Placebo in Low Back Pain
The primary objective of this study is to evaluate the efficacy and safety of BTDS compared to placebo in subjects with moderate to severe low back pain.
- Trial name
- NCT00346047
- Testing
- Buprenorphine Transdermal System
- Where
- 29 sites in Japan
- Volunteers
- 238 people
- Sponsor
- Mundipharma K.K.
Chronic Pain
Fast-Acting Subperception Study (FAST)
Study to Demonstrate the Value of Fast-Acting Subperception (FAST) using the Spectra WaveWriter™ Spinal Cord Stimulator System in the Treatment of Chronic Pain
- Trial name
- FAST (NCT04231409)
- Testing
- Boston Scientific Spectra WaveWriter SCS System
- Where
- 6 sites in United States
- Volunteers
- 41 people
- Sponsor
- Boston Scientific Corporation
Osteoarthritis
A Study to Determine the Difference in Low Contact Stress (LCS) Duofix Versus Low LCS Porocoat Knee Systems
The primary objective of this investigation is to test the hypothesis that the Duofix Tibial component results in a reduction of immediate postoperative pain compared to the LCS Porocoat version.
- Trial name
- NCT00733499
- Testing
- LCS Complete Duofix, LCS Complete Porocoat
- Where
- Ireland
- Volunteers
- 206 people
- Sponsor
- DePuy International
Acute, Post-operative Pain
Single Ascending Dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of ST-2427
This randomized, double-blind, placebo controlled, study will be conducted to evaluate the safety, tolerability, and pharmacokinetics of ST-2427.
- Trial name
- NCT04475198
- Testing
- ST-2427
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- SiteOne Therapeutics, Inc.
Coronary Artery Disease
Long-Term Follow-up Study of Patients Who Received PB127 Ultrasound Imaging Agent
The purpose of this study is to collect longer term follow-up information concerning health and survival on selected patients who received PB127 for injectable suspension in the pivotal trial (127-014).
- Trial name
- NCT00584714
- Where
- 39 sites in United States
- Volunteers
- 300 people
- Sponsor
- Point Biomedical
Healthy
Clinical Trial to Compare The Pharmacokinetics of A Pregabalin Controlled Release Tablet 300mg and Immediate Release Formulation
The purpose of this study is to compare the pharmacokinetics profiles of pregabalin sustained release tablet (300mg) to immediate release capsule(150mg * 2) while multiple dosing.
- Trial name
- NCT02103647
- Testing
- Immediate release capsule(lyrica 150mg * 2/day), sustained release tablet
- Where
- South Korea
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- IlDong Pharmaceutical Co Ltd
Dental Pain
Single Dose Study of N1539 in the Treatment of Pain Secondary to Dental Impaction Surgery
To evaluate the safety and efficacy of single IV doses of N1539 after dental impaction surgery.
- Trial name
- NCT00945763
- Testing
- N1539, Motrin
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Alkermes, Inc.
Pain, Post Operative Pain
Phase II Study of Inhaled AeroLEF for Analgesia After ACL Knee Surgery
To evaluate the safety and efficacy of self-titration to effective analgesia with inhaled AeroLEF in patients with moderate/severe acute pain in the post-surgical setting.
- Trial name
- Pain (NCT00791804)
- Testing
- AeroLEF
- Where
- 2 sites in Canada
- Volunteers
- 19 people
- Sponsor
- YM BioSciences
Spinal Fusion, Spondylolisthesis
Spine Registration Using 3D Scanning - Arise
The primary objective is to assess the capability of the device as measured by its consistency, its accuracy, and feedback from surgical staff over the study period.
- Conditions
- Spinal Fusion, Spondylolisthesis, Scoliosis, Sciatica
- Trial name
- NCT05195593
- Testing
- Optical 3D Scanner
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Advanced Scanners Inc.
Musculoskeletal Pain
Signal Relief Patch in Musculoskeletal Pain
assess the efficacy of the Signal Relief patch for the management of general musculoskeletal pain
- Trial name
- NCT05288114
- Testing
- Signal Relief Patch
- Where
- 2 sites in United States
- Volunteers
- 44 people
- Sponsor
- Signal Relief
Diabetic Neuropathy, Painful
PDN Post Market, Multicenter, Prospective, Global Clinical Study
The purpose of this post-market study is to evaluate the real-world experience of Nevro's Spinal Cord Stimulation (SCS) therapy in patients with chronic, intractable leg pain due to painful diabetic neuropathy (PDN).
- Trial name
- PDN-PM (NCT05301816)
- Testing
- Spinal Cord Stimulator (SCS)
- Where
- 8 sites in United States
- Volunteers
- 497 people
- Sponsor
- Nevro Corp
Osteoarthritis, Hip
ReNu™ Injection to Treat Hip Osteoarthritis Study
A pilot study to evaluate changes in hip function and pain in patients with osteoarthritis receiving the ReNu™ Hip Injection.
- Trial name
- NCT03063099
- Testing
- ReNu™ Injection
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- NuTech Medical, Inc
Pain
Fentanyl Transdermal Matrix Patch ZR-02-01 to Treat Chronic, Moderate to Severe Non-Malignant Pain
The purpose of this study is to evaluate the safety of the matrix fentanyl patch ZR-02-01 in providing relief of non-malignant chronic pain.
- Trial name
- NCT00126763
- Testing
- Fentanyl Transdermal Matrix Patch ZR-02-01
- Where
- 6 sites in United States
- Volunteers
- 105 people
- Sponsor
- ZARS Pharma Inc.
Interstitial Cystitis/Bladder Pain Syndrome
Study of V117957 in Interstitial Cystitis/Bladder Pain Syndrome
The purpose of this study is to evaluate the safety, tolerability and efficacy of V117957 in subjects with interstitial cystitis/bladder pain syndrome, compared to placebo.
- Trial name
- NCT06285214
- Testing
- V117957
- Where
- 24 sites in United States
- Volunteers
- 47 people
- Sponsor
- Imbrium Therapeutics
Osteoarthritis of the Knee
Hydros Joint Therapy and Hydros-TA Joint Therapy for Pain Associated With Knee Osteoarthritis (OA)
The purpose of this study is to evaluate the safety and performance of Hydros Joint Therapy (Hydros) and Hydros-TA Joint Therapy (Hydros-TA) for treatment of pain from osteoarthritis of the knee, in patients who have failed to…
- Trial name
- NCT01134406
- Testing
- Hydros Joint Therapy, Hydros-TA Joint Therapy, Synvisc-One
- Where
- Canada
- Volunteers
- 98 people
- Sponsor
- Carbylan Therapeutics, Inc.
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