Clinical trials: Pain Severity
Chronic Pain, Ptsd
Improving Dysregulated Neural Networks With EEG-neurofeedback
Comorbid PTSD in the context of chronic pain rehabilitation is a major problem. The lack of effective and efficient methods that can be integrated into current practice is needed.
- Trial name
- NCT06587919
- Testing
- Neurofeedback
- Where
- Denmark
- Volunteers
- 63 people
- Sponsor
- University of Southern Denmark
Colposcopy
Lidocaine Spray vs Coughing for Pain Relief During Colposcopy
Cervical cancer is the third most common genital cancer worldwide. The diagnosis of cervical cancer is performed with the cervical biopsy which is guided by the colposcopy.
- Trial name
- NCT03100565
- Testing
- local lidocaine spray, forced coughing
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Yuzuncu Yil University
Non-specific Low Back Pain
Dose Response of Neural Mobilization on Hamstring Flexibility in Low Back Pain
This study will be a randomized control trial and will be conducted in Riphah International Hospital, National orthopedic and specialist hospital, Riphah international hospital and Chambeli institute of physiotherapy.
- Trial name
- NCT05101200
- Testing
- High Dose Neural Mobilization Technique, Low Dose Neural Mobilization Technique
- Where
- Pakistan
- Volunteers
- 34 people
- Sponsor
- Riphah International University
Acute Pain, Regional Anesthesia Morbidity
Adductor Canal Catheter vs Local Infiltration of Analgesia for Total Knee Arthroplasty
The study is a prospective randomized controlled trial comparing local infiltration of analgesia in the knee joint and adductor canal catheters for postoperative analgesia following a primary Total Knee Arthroplasty (TKA).
- Trial name
- NCT02603900
- Testing
- ropivacaine, bupivacaine, Adductor Canal Catheter
- Where
- United States
- Sponsor
- Thomas Jefferson University
Preoperative Anxiety, Postoperative Pain
Effect of Mobile Phone Video Games on Preoperative Anxiety and Postoperative Pain in Children
This randomized controlled trial will evaluate the effect of mobile phone video game distraction on preoperative anxiety and postoperative pain in pediatric surgical patients.
- Conditions
- Preoperative Anxiety, Postoperative Pain, Elective Surgical Procedure
- Trial name
- VAPiC (NCT07128056)
- Testing
- Mobile phone video game distraction, Standard peri operative care
- Where
- Pakistan
- Volunteers
- 150 people
- Sponsor
- Fatima Numeri
Aneurysms, Arteriovenous Malformations
Neurosurgical Outcome Network
The evaluation of neurosurgical outcomes varies from center to center, and the predictive factors that determine these outcomes are not fully known or shared.
- Conditions
- Aneurysms, Arteriovenous Malformations, Cavernomas, Skull Base Tumors
- Trial name
- NEON (NCT06724029)
- Where
- 27 sites in Italy
- Volunteers
- 4,500 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Low Back Pain
Wallis Mechanical Normalization System for Low Back Pain
The purpose of this study is to compare improvement in low back pain with Wallis (interspinous process implant) to exercise and injections.
- Trial name
- NCT00134537
- Testing
- Interspinous process and dynamic stabilization, Conservative Care
- Where
- 17 sites in United States
- Volunteers
- 300 people
- Sponsor
- Zimmer Spine
Neuropathic Pain
The Role of N-acetyl-l-cysteine (NAC) as an Adjuvant to Opioid Treatment in Patients With Chronic Neuropathic Pain
This study will test whether treatment with N-acetyl-L-cysteine (NAC) is safe and decreases pain in patients with chronic neuropathic pain.
- Trial name
- NCT01840345
- Testing
- N-acetyl-l-cysteine
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Virginia Commonwealth University
Ocular Pain, Dry Eye
Study to Evaluate the Ocular Tolerance of SYL1001 in Healthy Volunteers
The purpose of this study is to determine whether SYL1001 is safe for the prevention and treatment of ocular pain and dry eye syndrome.
- Trial name
- NCT01438281
- Testing
- SYL1001
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sylentis, S.A.
Intracanal Medicament
Comparison of Inter-appointment Pain Reduction During Root Canal Treatment in Symptomatic Apical Periodontitis by Using Intracanal Medicaments; Chlorhexidine Gel and Single Antibiotic Paste Nitrofurantoin
This study is being conducted to find out which of two medications-Chlorhexidine Gel or Nitrofurantoin-works better in reducing pain between root canal treatment visits.
- Trial name
- NCT07198919
- Testing
- Chlorhexidine gel, Nitrofurantoin 100 MG
- Where
- Pakistan
- Volunteers
- 220 people
- Sponsor
- Altamash Institute of Dental Medicine
Cervical Radiculopathy
Thoracic Manipulation in Patients With Cervical Radiculopathy
Hypothesis: The group of Cervical Radiculopathy patients receiving thoracic thrust manipulation will demonstrate immediate and short term significant clinically important changes in outcomes when compared to the sham manipulation…
- Trial name
- NCT01495728
- Testing
- Thrust Manipulation - Thoracic Spine
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Spine and Sport, Georgia
Phantom Limb Pain, Phantom Pain
VR to Evaluate Phantom Limb Pain
The objective of this study is to develop a virtual rehabilitation system that can be used to effectively treat Phantom Limb Pain (PLP) within the research setting and for at-home use by individuals with upper and lower extremity…
- Conditions
- Phantom Limb Pain, Phantom Pain, Phantom Sensation, Phantom Limb Syndrome With Pain
- Trial name
- NCT05915065
- Testing
- Coapt Phantom Limb Pain Management System
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Shirley Ryan AbilityLab
Postoperative Pain in Orthopaedics
Clinical Study of HRS-2129 for Postoperative Analgesia in Orthopaedics
The study is being conducted to evaluate the safety, and efficacy of HRS-2129 for Postoperative analgesia in orthopaedics. To explore the reasonable dosage of HRS-2129 for Postoperative analgesia in orthopaedics.
- Trial name
- NCT06780267
- Testing
- HRS-2129, Tramadol Hydrochloride SR Tablets
- Where
- China
- Volunteers
- 199 people
- Sponsor
- Shandong Suncadia Medicine Co., Ltd.
Migraine Disorders, Headache, Migraine
Effectiveness of Onabotulinumtoxin A (Botox) in Pediatric Patients Experiencing Migraines: A Study in the Pediatric Pain Population
The purpose of the research is to examine the outcomes of pediatric patients receiving Botulinum toxin type A (Botox ®) for the treatment of migraine.
- Conditions
- Migraine Disorders, Headache, Migraine, Pediatrics
- Trial name
- NCT03055767
- Testing
- OnabotulinumtoxinA
- Where
- 2 sites in United States
- Volunteers
- 17 people
- Sponsor
- University of California, Irvine
Pain
Efficacy and Safety of DEC103 in Pain Control Associated to Intrauterine Device (IUD) Insertion
The purpose of this study is to evaluate the efficacy and safety of DEC103 in the pain control associated with IUD insertion in women with 18 to 49 years.
- Trial name
- DEC103 (NCT05800392)
- Testing
- DEC103
- Where
- Brazil
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- EMS
Migraine Disorders
Pain Resilience and Holistic Health Care of Migraine
The purpose of this study is to investigate how pain resilience (as a personality characteristic or a strength) moderate the efficacy of treatment for patients with migraine.
- Trial name
- NCT04743492
- Testing
- cognitive behavioral therapy
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- Changhua Christian Hospital
Non-specific Chronic Low Back Pain
V-sitting Posture Stabilization Versus Modified Clamshell in Patients With Non-specific Chronic Low Back Pain.
The aim of this study is to compare the v-siting posture stabilization and clamshell exercises on pain and disability in patients with non-specific chronic low back pain.
- Trial name
- NCT05393336
- Testing
- V-sitting posture stabilization, Modified clamshell exercises
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Riphah International University
Superficial Basal Cell Carcinoma
Superficial Basal Cell Carcinoma Treatment With Topical Photodynamic Therapy With Fractionated 5-aminolevulinic Acid 20% Versus Two Stage Methylaminolevulinate
Skin cancer is the most common cancer in Caucasians, and a basal cell carcinoma (BCC) being the most common skin cancer with around 44,000 new tumours per year, and its incidence is still rising.
- Trial name
- NCT01491711
- Testing
- Methylaminolevulinate PDT in 2 sessions, Fractionated 5-aminolevulinic acid hydrochloride 20% gel PDT
- Where
- 3 sites in Netherlands
- Volunteers
- 162 people
- Sponsor
- Maastricht University Medical Center
Diabetic Neuropathies, Diabetes Mellitus
Efficacy and Safety of the Combination of Ten Elements for 6 Months in Patients With Diabetic Neuropathy : A Pilot Study
To investigate the efficacy of Superoxide Dismutase (SOD, 70 UI), Palmitoylethanolamide (PEA, 300 mg) Alpha Lipoic Acid (ALA, 300 mg), vitamins B6 (1.5 mg), B1 (1.1 mg), B12 (2.5 mcg), E (7.5 mg), Nicotinamide (9 mg) and minerals…
- Conditions
- Diabetic Neuropathies, Diabetes Mellitus, Dietary Supplement
- Trial name
- NCT05984771
- Testing
- Epineuron
- Where
- Greece
- Volunteers
- 70 people
- Sponsor
- Aristotle University Of Thessaloniki
Pilates Exercises, Nonspecific
Pilates Exercises on Nonspecific Low Back Pain in Postnatal Women
This study aims to investigate the effects of Pilates for postnatal women with Non-specific low back pain (NSLBP).
- Conditions
- Pilates Exercises, Nonspecific, Low Back Pain, Postnatal Women
- Trial name
- NCT07359144
- Testing
- Pilates program + Home exercise program, Home exercise program
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Kafrelsheikh University
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