Clinical trials: Pain Severity
Knee Pain, Chronic Osteoarthritis
ROSA Total Knee Investigational Testing Authorization Study
This is a prospective, single-center clinical study designed to facilitate the collection and evaluation of workflow efficiency, patient pain and function, and adverse event data.
- Conditions
- Knee Pain, Chronic Osteoarthritis, Avascular Necrosis of Femoral Condyle, Moderate Varus, Valgus or Flexion Deformities
- Trial name
- NCT03970629
- Testing
- PERSONA Total Knee
- Where
- Canada
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Zimmer Biomet
Osteo Arthritis Knee, Osteoarthritis
MRgFUS in the Treatment of Osteoarthritic Knee Pain
A double-blind placebo-controlled randomized clinical trial to evaluate the efficacy of magnetic resonance-guided focused ultrasound surgery (MRgFUS) in the treatment of pain caused by knee osteoarthritis (OA)
- Conditions
- Osteo Arthritis Knee, Osteoarthritis, Osteoarthritis, Knee
- Trial name
- NCT03453372
- Testing
- MRgFUS Treatment
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Istituto Ortopedico Rizzoli
Sciatica
Pain Relief by Platelet-rich Plasma (PRP) Treatment
Past PRP therapy is not sufficient for some part of patients.In this clinical research, The integrated application of PRP with extracellurar matrix and some type of stem cell technique.
- Trial name
- NCT01749839
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Saint Bernard Mission University
Psychosomatic Symptoms, Temporomandibular Disorder (TMD)
Psychosomatic Symptoms in Patients With Myofascial Pain and Temporomandibular Joint Dysfunction
Temporomandibular joint disorder poses an intricate etiology. Biomechanical, neuromuscular and psychosocial factors may contribute to the disorder among which psychological and psychosocial disturbances have shown strong direct…
- Trial name
- Psychosomatic (NCT07385781)
- Testing
- Casr
- Where
- Pakistan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Bahria University
Ketamine, Adjuvant
Ketamine as an Adjuvant in External Oblique Intercostal Plane Block for Post Thoracotomy Pain
The aim of this study is to evaluate the role of ketamine as an adjuvant in external oblique intercostal plane block for post thoracotomy pain.
- Conditions
- Ketamine, Adjuvant, External Oblique Intercostal Plane Block, Thoracotomy
- Trial name
- NCT07138781
- Testing
- Ketamine, 29 ml bupivacaine 0.25% + 1 ml saline
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Tanta University
Neck Pain
The Effectiveness of Postural Stabilization Exercises in Patients With Chronic Neck Pain
This study aimed to evaluate the effect of postural stabilization exercises given in addition to cervical stabilization on craniovertebral angle, neck disability index, and quality of life in people with chronic neck pain.Sixty…
- Trial name
- NCT06578481
- Testing
- Exercises
- Where
- Cyprus
- Volunteers
- 60 people
- Sponsor
- European University of Lefke
Primiparity (First-Time Mothers), Breastfeeding
The Effect of Music Play and Stress Ball Application on Placental Separation Time, Episious Pain and Breastfeeding Success
Although the female body and fetus are physiologically equipped to carry out the birthing process, the increasing medical interventions in the birthing process today are pushing women into the background during labor.
- Conditions
- Primiparity (First-Time Mothers), Breastfeeding, Episiotomy, Labour
- Trial name
- NCT07706881
- Testing
- music performance, stress ball squeezing, music listening and stress ball squeezing
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Bitlis Eren University
Necrotic Teeth With Chronic Apical Periodontitis
Regenerative Endodontics in Mature Necrotic Teeth
The goal of this clinical trial is to learn if nanochitosan can achieve regeneration in mature necrotic teeth. It will also provide data about the healing potential \& postoperative pain after using different irrigation…
- Trial name
- NCT07584928
- Testing
- Intervention 1: 1% nanochitosan, Intervention 2: 1% nanochitosan & 17% EDTA
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Suez Canal University
Coronary Artery Disease, Stable Angina
MR INFORM - MR Perfusion Imaging to Guide Management of Patients With Stable Coronary Artery Disease
The purpose of this study is to determine if MR Perfusion Imaging is non-inferior to coronary angiography with measurement of Fractional Flow Reserve (FFR) in guiding management of patients with stable chest pain.
- Conditions
- Coronary Artery Disease, Stable Angina, Myocardial Ischaemia
- Trial name
- NCT01236807
- Testing
- MR perfusion guidance, FFR guidance
- Where
- United Kingdom
- Volunteers
- 915 people
- Sponsor
- King's College London
Joint Pain
NAtive Collagen Type II In Healthy VoluntEers With Joint Discomfort
Collagen Supplement is a natural ingredient that contains native collagen derived from chicken sternum. Collagen Supplement is efficacious and safe on healthy subjects as compared to placebo.
- Trial name
- ACTIVE (NCT05282992)
- Testing
- Native type II collagen
- Where
- Spain
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Bioiberica
Scapular Pain
The Correlation Between Neck Posture and Scapular Posture & the Effect Stabilization Exercises for the Scapula
Recently, many office workers and young people have postural abnormalities, including forward head posture (FHP) and rounded shoulder posture (RSP).
- Trial name
- NCT07500571
- Testing
- Self-Exercise only, Professional exercise rehabilitation therapy
- Where
- South Korea
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Hallym University Dongtan Sacred Heart Hospital
Shoulder Arthroscopy
Continuous Cervical Erector Spinae Plane Block Versus Interscalene Nerve Block in Shoulder Arthroscopic Surgery
Shoulder arthroscopic surgery is associated with moderate to severe postoperative pain, which may hinder early mobilization and functional recovery.
- Trial name
- NCT07369271
- Testing
- Continuous Cervical Erector Spinae Plane Block, Continuous Interscalene Block, No intervention
- Where
- Taiwan
- Volunteers
- 165 people
- Sponsor
- National Cheng-Kung University Hospital
This Study Will Evaluate Whether TXA Reduces Pain
Effect of Tranexamic Acid (TXA) Administered Prior to Shoulder Arthroscopy on Postoperative Pain Medication Usage: A Randomized Controlled Trial
To our knowledge, no studies examining the use of TXA after shoulder arthroscopy in an outpatient setting have been published. This study will evaluate whether TXA reduces pain as measured by opioid consumption and a visual…
- Trial name
- NCT06920264
- Testing
- Tranexamic acid
- Where
- United States
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- St. Louis Joint Replacement Institute
Irritable Bowel Syndrome, Functional Dyspepsia
The Multi-disciplinary Treatment of Functional Gut Disorders Study
Randomised controlled trial comparing standard outpatient clinic treatment with multi-disciplinary clinic treatment for functional gastrointestinal disorders.
- Conditions
- Irritable Bowel Syndrome, Functional Dyspepsia, Constipation - Functional, Faecal Incontinence
- Trial name
- MANTRA (NCT03078634)
- Testing
- Multi-disciplinary clinic model, Standard outpatient care
- Where
- Australia
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- St Vincent's Hospital Melbourne
Rheumatoid Arthritis
Mulligan Mobilization in Rheumatoid Hand
The goal of this randomized-controlled study is to learn about the effectiveness of the Mulligan mobilization in rheumatoid hands.
- Trial name
- NCT05660629
- Testing
- Mulligan Mobilization
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people
- Sponsor
- Kirsehir Ahi Evran Universitesi
Fibromyalgia
MDMA-assisted Therapy for Fibromyalgia
Fibromyalgia is a debilitating chronic pain disorder. Based on prior research with MDMA, it can be hypothesized MDMA-assisted therapy in fibromyalgia patients may increase the range of positive emotions, interpersonal trust, and…
- Trial name
- NCT06066853
- Testing
- MDMA
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Spaulding Rehabilitation Hospital
Acute Low Back Pain
DISCO - Influence of a Simple Information Booklet on the Evolution of Acute Low Back Pain (LBP)
To assess the impact of standardized written information on outcome in acute LBP.
- Trial name
- NCT00343057
- Testing
- Patients' questionnaire
- Where
- France
- Volunteers
- 2,830 people
- Sponsor
- Sanofi
Herpes Zoster, Postherpetic Neuralgia
Shingles Prevention Study
The incidence and severity of HZ (or shingles), as well as the frequency and severity of its complications, increases markedly with increasing age. More than half of all cases occur in persons over the age of 60.
- Trial name
- SPS (NCT00007501)
- Testing
- Varicella-zoster vaccine
- Where
- 22 sites in United States
- Volunteers
- 38,456 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Post-operative Pain Management, Hip Fracture Surgery
Comparison of Analgesic Efficacy of PENB Block with FICB in Post Operative Hip Fracture Patients
This study was done to evaluate two different interventions for postoperative pain control in patients undergoing hip surgeries. Fifty patients, divided in two equal groups, were included in the study.
- Trial name
- NCT05810012
- Testing
- PENG block, FICB Block
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Pain Medicine Department
Total Knee Arthroplasty
Trial Comparing a Multi-Modal Pain Protocol With and Without Opioids Following Total Joint Arthroplasty
To help curb the use of opioid medications following orthopedic surgery investigators have developed a new multi-modal pain pathway. Investigators aim to compare this regimen with and without the inclusion of opioid medications.
- Trial name
- NCT03845881
- Testing
- Oxycodone
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Mayo Clinic
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