Clinical trials: Pain Severity
Knee Osteoarthristis
Gender Based Comparison of the Effects of Sensory Modulated Graded Weight Bearing Physiotherapy In Adults With Knee Osteoarthritis
This comparative experimental study aims to evaluate the effectiveness of Sensory-Modulated Graded Weight-Bearing Physiotherapy (SMGWBP) in patients with knee osteoarthritis and compare treatment outcomes between male and female…
- Trial name
- GSMGWBP (NCT07784998)
- Testing
- Sensory-Modulated Graded Weight-Bearing Physiotherapy
- Where
- Pakistan
- Volunteers
- 52 people
- Sponsor
- Shifa Tameer-e-Millat University
Postoperative Pain
The Transversus Abdominis Plane Block: A Prospective Randomized Clinical Trial Using EXPAREL.
The purpose of the study is to evaluate the effectiveness of EXPAREL in a transversus abdominis plane block by assessing the demand of postoperative narcotic, length of hospital stay and incidence of postoperative complications.
- Trial name
- NCT02263963
- Testing
- Exparel, TAP Block
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Corewell Health West
Acute Appendicitis
Peritoneal Closure Versus Non Closure During Open Appendectomy
There has been no consensus over closure versus non closure of peritoneum during abdominal operations. The aim of this study is to compare the effect of peritoneal closure versus non closure over postoperative pain, early…
- Trial name
- NCT02803463
- Testing
- open appendectomy with peritoneal closure, open appendectomy without peritoneal closure
- Where
- Turkey (Türkiye)
- Volunteers
- 112 people
- Sponsor
- Bezmialem Vakif University
Children, Preschool, Pain and Anxiety
Storytelling Caterpillar - Pain, Anxiety, and Satisfaction
This randomized controlled trial aims to evaluate the effect of using the "Storytelling Caterpillar" toy on pain, anxiety, and parental satisfaction during blood draw procedures in children aged 3 to 6 years.
- Trial name
- SC-PAS (NCT07127432)
- Testing
- The Storytelling Caterpillar
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Koç University
Knee Arthropathy, Knee Osteoarthritis
NLR and PLR Levels Following IPACK Block in Knee Arthroplasty
Effect of iPACK block on NLR and PLR following knee arthroplasty
- Conditions
- Knee Arthropathy, Knee Osteoarthritis, Knee Pain Chronic
- Trial name
- NCT06304298
- Testing
- 0.9% Sodium Chloride Injection, Ropivacaine 0.2% Injectable Solution
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Poznan University of Medical Sciences
Arthroplasty Complications, Pain, Joint
Efficacy of iPACK After Unilateral TKA
Total knee arthroplasty (TKA) is a common orthopedic procedure associated with severe postoperative pain which may limit patient rehabilitation and hospital discharge.
- Conditions
- Arthroplasty Complications, Pain, Joint, Arthritis Knee, Regional Anesthesia Morbidity
- Trial name
- NCT04565093
- Testing
- iPACK, Periarticular local infiltration analgesia (LIA)
- Where
- Saudi Arabia
- Volunteers
- 80 people
- Sponsor
- King Khalid University Hospital
Asymptomatic Molar Teeth With Periapical Lesions
Postoperative Pain After Root Canal Preparation Using Different Engine-driven Systems
A hundred twenty patients who had an asymptomatic mandibular molar teeth with periapical lesion were included. For each patient, teeth were prepared with Reciproc Blue or Protaper Universal instruments.
- Trial name
- NCT04454814
- Testing
- Protaper Universal instruments, Reciproc Blue instruments
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ege University
Sleep Disorders, Sciatica
Intravascular Laser and Electroacupuncture for Sciatica With Insomnia: A Pilot Trial
Sciatica is a common condition worldwide, with prevalence rates ranging from 1.2% to 43%. Chronic sciatica is often associated with sleep disturbances, forming a bidirectional loop where persistent nociceptive input disrupts…
- Trial name
- NCT06755593
- Testing
- Electroacupuncture, Intravascular Low-Level Laser Therapy (ILIB)
- Where
- Vietnam
- Volunteers
- 66 people
- Sponsor
- Le Hoang Minh Quan
Temporomandibular Disorders (TMD)
Transcutaneous Electrical Nerve Stimulation for Early Pain Control in Temporomandibular Disorders
To evaluate whether adding conventional transcutaneous electrical nerve stimulation (TENS) to a standard conservative regimen (patient education, pharmacotherapy, and a home exercise programme) provides additional short- and…
- Trial name
- NCT07744893
- Testing
- Standard Conservative Therapy, Transcutaneous Electrical Nerve Stimulation (TENS)
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Balikesir University
Low Back Pain
EMG Activation of Gluteal Musculature During Exercises With and Without Resistance
The gluteus medius (Gmed) and gluteus maximus (Gmax) muscles are important components in the treatment of many lower limb injuries.
- Trial name
- GlutEMG02 (NCT01841216)
- Testing
- Lower Body Exercises with and without resistance
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sport and Spine Rehab Clinical Research Foundation
Pain Management, Laparascopic Sleeve Gastrectomy
Ketamine for Shoulder Pain Following Laparoscopic Gastric Sleeve Surgery
Shoulder pain is a well-recognized complaint following laparoscopic surgery. It is underlying mechanism has various causes, therefore, modalities in management and prevention of this sort of pain are numerous with different…
- Trial name
- NCT07429916
- Testing
- Intraoperative ketamine
- Where
- Jordan
- Volunteers
- 50 people
- Sponsor
- King Abdullah University Hospital
Renal Colic
Paracetamol-Tramadol and Paracetamol-caffeine Versus Placebo in the Emergency Discharge Treatment of Renal Colic
This is a prospective, randomized, single-blind study. Patients included in the study after successful treatment of the acute attack were randomized upon discharge from the Emergency Department into three groups: oral…
- Trial name
- RC (NCT06345716)
- Testing
- paracétamol tramadol, Paracétamol cafeine
- Where
- Tunisia
- Volunteers
- 1,500 people
- Sponsor
- University of Monastir
Pain, Low Back Pain
An Efficacy and Safety Study for Tapentadol Extended Release (JNS024ER) in Chronic Pain Participants
The purpose of this study is to evaluate the efficacy, safety and to explore the pharmacokinetics (how drugs are absorbed in the body, how they are distributed within the body and how they are removed from the body over time) of…
- Conditions
- Pain, Low Back Pain, Back Pain, Osteoarthritis, Knee
- Trial name
- NCT01124604
- Testing
- Tapentadol Hydrochloride
- Where
- 19 sites in Japan
- Volunteers
- 91 people
- Sponsor
- Janssen Pharmaceutical K.K.
Pain, Postoperative, Hip Arthroplasty
CMP vs Fascia Iliaca Block
Complete motorsparing protocol (CMP) has been developed to try to minimize the motor nerve block that is created when using Facia iliaca nerve block.
- Trial name
- NCT04426058
- Testing
- CMP, Fascia Illica
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Loyola University
Family Planning
Indomethacin Use in Pain Relief During Intrauterine Device Insertion
The aim of the investigators study is to test the analgesic effect of rectal indomethacin during Intrauterine device insertion.
- Trial name
- INDO-IUD (NCT02711358)
- Testing
- indomethacin suppositories
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Assiut University
Inguinal Hernia, Postoperative Pain
Comparison of Lornoxicam and Paracetamol for Pre-emptive Intravenous Analgesia for Elective Inguinal Hernia Repair
The purpose of this study is to determine whether lornoxicam or paracetamol is more effective in providing pre-emptive analgesia for adult patients undergoing elective unilateral inguinal hernia repair under general anesthesia.
- Trial name
- NCT01069055
- Testing
- Sterile Saline, Intravenous lornoxicam, Intravenous paracetamol
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Diskapi Teaching and Research Hospital
Acute Pain
Nefopam/Paracetamol Fixed Dose Combination in Acute Pain After Impacted Third Molar Extraction
This study aims to evaluate the analgesic efficacy of single and multiple doses of a new fixed dose combination of nefopam hydrochloride 30 mg and paracetamol 500mg taken orally in comparison to each single component.
- Trial name
- NCT04622735
- Testing
- nefopam hydrochloride 30mg / paracetamol 500mg X2, Paracetamol 500 Mg Oral Tablet X2, Nefopam HCl 30 MG Oral Tablet X2
- Where
- 19 sites in Belgium, France and 3 more
- Volunteers
- 321 people
- Sponsor
- Unither Pharmaceuticals, France
Post Operative Pain, Spine Surgery
Effects of Continuous ESP Catheters on Recovery, Pain and Opioid Consumption After Multilevel Spine Surgery
Single-shot erector spinae plane (ESP) blocks (ESPB) are emerging as an intervention to improve pain and minimize opioid consumption after lumbar spine surgery.
- Trial name
- NCT05494125
- Testing
- Ropivacaine
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Chronic Pain, Spinal Cord Injuries
Improving Functioning in Persons With Chronic Pain Post-SCI Through Virtual Classroom Education
Chronic pain (pain that is that is present for a long period of time) is very common among people with spinal cord injury (SCI).
- Trial name
- NCT02561676
- Testing
- Education Program Type 1, Education Program Type 2
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Kessler Foundation
Vaginal Packing Following Laparoscopic Sacrocolpopexy, Pelvic Organ Prolapse
Vaginal Packing After Laparoscopic Sacrocolpopexy
Vaginal packing is used routinely following vaginal reconstructive surgery, however, no recommendation regarding vaginal packing after laparoscopic sacrocolpopexy exists.
- Trial name
- NCT02943525
- Testing
- vaginal packing
- Where
- Czechia
- Volunteers
- 253 people
- Sponsor
- Charles University, Czech Republic
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