Clinical trials: Pain Severity
Health Services Misuse, Physician's Practice Patterns
Primary Care Clinician Commitments to Choosing Wisely®
This pragmatic trial examines the uptake and effects of primary care clinician commitments to follow 3 Choosing Wisely® recommendations.
- Conditions
- Health Services Misuse, Physician's Practice Patterns, Guideline Adherence, Unnecessary Procedures
- Trial name
- NCT02247050
- Testing
- Commitment invitation
- Where
- 6 sites in United States
- Volunteers
- 45 people
- Sponsor
- University of Michigan
Overactive Bladder (OAB), Botulinum Toxin Injection
Pretibial TENS for Pain and Anxiety During Intravesical OnabotulinumtoxinA Injection
Overactive bladder is a common condition that causes a frequent, urgent need to urinate and can significantly reduce quality of life.
- Conditions
- Overactive Bladder (OAB), Botulinum Toxin Injection, Procedural Pain Relief, Anxiety
- Trial name
- NCT07707791
- Testing
- Active Pretibial TENS
- Volunteers
- 68 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Postoperative Pain
Predictors of Postoperative Pain
The purpose of the study is to prove that pain scores generated from painful stimuli applied preoperatively may help identify the inter-individual variability in pain perception.
- Trial name
- NCT01449318
- Testing
- Thermal Sensory Analyzer (Senselab)
- Where
- 2 sites in Lebanon
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Mitochondrial Diseases, Developmental Delay Disorder
Reference Values of Intraepidermal Nerve Fiber Density in Children and Small Fiber Neuropathy in Neurodevelopmental Disorders
Background: Small-Fiber-Neuropathy describes the degeneration of mildly or unmyelinated nerve fibers and causes neuropathic pain and autonomic dysfunction.
- Conditions
- Mitochondrial Diseases, Developmental Delay Disorder, Small Fiber Neuropathy, Cerebral Palsy
- Trial name
- SFN_children (NCT05645874)
- Testing
- Skin biopsy
- Where
- Germany
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- Heinrich-Heine University, Duesseldorf
Abdominal Pain
Abdominal Pain Management and Point-of-care Ultrasound in the Emergency Department
Background: Abdominal pain is one of the most common reasons for admission to the emergency department (ED). This study aimed to investigate the effect of point-of-care ultrasound (POCUS) performed during the initial evaluation…
- Trial name
- NCT05402774
- Testing
- point-of-care ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- Sakarya University
Neuropathic Pain, Cancer
Vulnerability and Risk of Neuropathic Pain in Cancer
Successive and repeated therapeutic interventions during cancer management - surgery, chemotherapy, radiotherapy - can all, to varying degrees, generate acute pain, central pain sensitization and chronic pain.
- Conditions
- Neuropathic Pain, Cancer, Predictive
- Trial name
- CANOPY (NCT06511674)
- Testing
- Cognitive-emotional and pain assessments
- Where
- 19 sites in France
- Volunteers
- 625 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Pain, Inflammation
Safety/Efficacy of Bromfenac Ophthalmic Solution for Ocular Inflammation and Pain Associated With Cataract Surgery
The primary objective of this study is to investigate the efficacy and safety of bromfenac ophthalmic solution for treatment of ocular inflammation and pain in subjects who undergo cataract extraction and intraocular lens…
- Trial name
- NCT00333918
- Testing
- bromfenac ophthalmic solution
- Where
- United States
- Volunteers
- 522 people
- Sponsor
- Bausch & Lomb Incorporated
Unstable Angina
Research on the Clinical Effect of Effective Prescription in Treating Unstable Angina.
This study evaluates the clinical efficacy of the famous prescription in the treatment of unstable angina pectoris. All of the patients will be divided into 4 arms according to their syndrome type.
- Trial name
- NCT03171597
- Testing
- Anti-Platelet Drugs, Lipid Regulating Drugs, Coronary Vasodilator
- Volunteers
- 240 people
- Sponsor
- Jun Li
Prostate Cancer Metastatic, Bone Metastases
Registry of Treatment Outcomes of Symptomatic Metastasized Castration Resistant Prostate Cancer Treated With Radium-223
Radium-223 is the 5th treatment for metastasized castration resistant prostate cancer with a proven overall survival benefit. The improved survival of Radium-223 over placebo was demonstrated in the ALSYMPCA trial, which included…
- Trial name
- ROTOR (NCT03223597)
- Testing
- Radium-223 dichloride
- Where
- 20 sites in Netherlands
- Volunteers
- 300 people
- Sponsor
- The Netherlands Cancer Institute
Pain, Intractable, Pain, Chronic
Study to Evaluate Neuromodulation Subject Experience With Contemporary Spinal Cord Stimulation (SCS) Modalities for Chronic Pain
Medtronic, Inc. is sponsoring the SENSE SCS clinical study, a prospective, multi-center, post-market, non-randomized, observational study with a hybrid decentralized model of execution, utilizing a mobile application for the…
- Trial name
- SENSE SCS (NCT05775510)
- Testing
- Commercially available neurostimulation systems
- Where
- 10 sites in United States
- Volunteers
- 91 people
- Sponsor
- MedtronicNeuro
Endometriosis, Endometriosis (Diagnosis)
Impact of the Antihistamine Desloratadine on the Quality of Life and Dysmenorrhea in Patients With Endometriosis
Endometriosis is a chronic inflammatory disease affecting approximately 10% of women in their reproductive years. It is characterized by the presence of endometrial-like tissue outside the uterine cavity.
- Conditions
- Endometriosis, Endometriosis (Diagnosis), Endometriosis and Dysmenorrhea, Endometriosis Associated Pelvic Pain
- Trial name
- NCT07821320
- Testing
- Desloratadine
- Where
- Austria
- Volunteers
- 60 people
- Sponsor
- Medical University of Vienna
Neonatal, Pain
The Effect of Music, White Noise and Heart Sound on Neonatal Pain
Infants are exposed to many painful procedures during their stay in the Neonatal Intensive Care Unit (NICU). Some epidemiological studies report that infants experience an average of 7.5-14 painful procedures per day per infant…
- Trial name
- NCT05828420
- Testing
- White noise, Heart sound, Music
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Labor Pain
The WE Pilot Study: Walking Epidurals
The primary objective of the study is to assess the feasibility of a walking epidural protocol in our center. This study will provide a small data set for a larger prospective randomized controlled study.
- Trial name
- NCT03710382
- Testing
- Walking epidural
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Pain, Pacemaker Ddd
Evaluation of the Effectiveness of the Supraclavicular Block Associated With a Pecs Blocks I to Ensure Analgesia When Placing a Pacemaker
Pacemakers are currently placed at the Erasmus Hospital under local anesthesia performed by the surgeon, and the amount of local anesthetic agents sometimes reach the maximum permitted doses, with a risk of systemic toxicity.
- Trial name
- NCT04067024
- Testing
- Local anesthesia made by surgeon, Regional anesthesia group
- Where
- Belgium
- Volunteers
- 31 people
- Sponsor
- Erasme University Hospital
Neck Pain, Chronic Neck Pain
Effect of Added Load on Map-Based Proprioceptive Training in Chronic Neck Pain
The purpose of this study is to find out whether adding an external load to a map-based cervical proprioceptive training program provides additional benefit for people with chronic neck pain.
- Trial name
- NCT07900295
- Testing
- Weightless map-based proprioceptive training, Weighted map-based proprioceptive training
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Hacettepe University
Spinal Anesthesia
Impact of Listening to Music on Anxiety Postoperative in a Postanesthesic Care Unit (PACU) After Spinal Anesthesia
Our hypothesis is that listening to music has a beneficial effect on the French population receiving spinal anesthesia for a scheduled procedure.
- Trial name
- MusicAnx-SSPI (NCT05002257)
- Testing
- music therapy, No music therapy
- Where
- France
- Volunteers
- 123 people
- Sponsor
- CHU de Reims
Sickle Cell Disease, Chronic Pain
MUSic Therapy to Improve Quality Of Life in Sickle Cell Disease (MUSIQOLS)
The purpose of this pilot study is to investigate the effects of a 6-session music therapy protocol on the pain, mood, quality of life, coping skills, and self-efficacy of adult patients with sickle cell disease (SCD) as compared…
- Trial name
- NCT03556657
- Testing
- Music Therapy
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University Hospitals Cleveland Medical Center
Pain
Superiority Study for Pain Treatment After Cesarean
The purpose of this study is to investigate adequate pain treatment for patients after cesarean. In this study oral opioids were compared to intravenous opioids as they are supposed to provide superior pain control.
- Trial name
- NCT01115101
- Testing
- Oral Oxycodon, Piritramid
- Where
- Germany
- Volunteers
- 239 people
- Sponsor
- Max Dieterich
Back Pain, Low Back Pain
Neck and Low Back Pain in Physical Therapy Students at The University of the West Indies, Mona, Jamaica
The purpose of this study is to determine the prevalence of neck and low back pain among physical therapy students enrolled at The University of the West Indies, Mona.
- Conditions
- Back Pain, Low Back Pain, Musculoskeletal Pain, Spine Health
- Trial name
- NCT07177001
- Testing
- Clinical Control Group (Group A), Spine Exercise Program (Group B)
- Where
- Jamaica
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- The University of The West Indies
Serratus Plane Block, Chronic Pain
Serratus Plane Block in Preventing Postoperative Pain of Mastectomy
A prospective, double-blinded randomized controlled, 1-year follow-up study was designed to compare the analgesic effect of serratus plane block (SPB) after breast cancer surgery.
- Conditions
- Serratus Plane Block, Chronic Pain, Breast Cancer
- Trial name
- NCT03615430
- Testing
- serratus plane block with local anesthetic, serratus plane block with saline
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Feng Xia
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