Clinical trials: Pain Severity
Cervical Radiculopathy
Effect of Manual Therapy on Sensory Features in Patients With Cervical Radiculopathy
Background \& Purpose: Cervical radiculopathy is a neurological disorder, which commonly results because of nerve compression. There are different types of physical therapy interventions that are used for cervical radiculopathy.
- Trial name
- NCT03328351
- Testing
- manual therapy, Superficial soft tissue massage
- Where
- 2 sites in Saudi Arabia
- Volunteers
- 28 people
- Sponsor
- Imam Abdulrahman Bin Faisal University
Bruxism, Myofascial Pain
Botulinum Toxin Type A Versus Oral Ibuprofen for Bruxism
This randomized controlled trial evaluated the effectiveness of Botulinum Toxin Type A compared with oral ibuprofen in reducing pain and improving oral health-related quality of life in patients with sleep bruxism and jaw muscle…
- Trial name
- NCT07732751
- Testing
- Botulinum Toxin Type A 100U, Ibuprofen
- Where
- Cyprus
- Volunteers
- 40 people
- Sponsor
- Cyprus Health and Social Sciences University
Hemiplegic Shoulder Pain
Laser Therapy Versus Neuromuscular Electrical Nerve Stimulation at Hemiplegic Shoulder Pain
This study aimed to investigate whether laser and neuromuscular electrical nerve stimulation applied in addition to conventional physical therapy exercises in hemiplegic shoulder pain seen in patients with stroke provides an…
- Trial name
- NCT06428851
- Testing
- Laser therapy, Neuromuscular electrical nerve stimulation, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Hitit University
Fibromyalgia
Effectiveness of Pain Neuroscience Education and Strength Training in Fibromyalgia
The main goal of this study is to get to know if applying both, pain neuroscience education (PNE) plus strength training (ST) will reduce the pain of fibromyalgia (FM).
- Trial name
- PNE-ST-FM (NCT04855851)
- Testing
- PAIN NEUROSCIENCE EDUCATION AND STRENGTH TRAINING, USUAL CARE
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Manuel Rebollo Salas
Obesity
Pain Control in Bariatric Patients: EXPAREL(R) vs. the On-Q(R) Pain Ball
This study was conducted to compare the effectiveness of two local pain control methods in bariatric patients by assessing the amount of postoperative pain and amount of postoperative pain medications needed.
- Trial name
- NCT02142829
- Testing
- EXPAREL, On-Q Pain Ball
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- Pacira Pharmaceuticals, Inc
Labor Pain, Virtual Reality
Virtual Reality in Labor and Delivery for Reduction in Pain
The purpose of this study is to identify whether use of virtual reality devices can improve the pain management of women in labor and delivery.
- Conditions
- Labor Pain, Virtual Reality, Alternative Medicine
- Trial name
- NCT03437031
- Testing
- Virtual Reality device
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Fentanyl, Platelet Reactivity
Platelet Reactivity With Fentanyl, Morphine, or no Narcotic
The goal is to determine whether fentanyl and morphine have similar effects in reducing aspirin's effect upon platelets in emergency department patients with chest discomfort.
- Trial name
- NCT05367336
- Testing
- Morphine, Fentanyl
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Corewell Health South
Diabetic Peripheral Neuropathic Pain
Ranolazine for Diabetic Peripheral Neuropathic Pain (DPNP)
The purpose of this trial is to determine if patients suffering from diabetic peripheral neuropathic pain treated with ranolazine will have a greater reduction in pain compared to placebo.
- Trial name
- NCT02156336
- Testing
- Ranolazine
- Where
- 3 sites in United States
- Volunteers
- 4 people
- Sponsor
- Horizons International Peripheral Group
Spinal Cord Injury + Peripheral Nerve Diseases
Assessment of Neuropathic Pain
Development of neuropathic pain is one of the most disabling sequels after spinal cord injury (SCI) and in peripheral nerve diseases.
- Trial name
- NCT02138344
- Where
- Switzerland
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Non-specific Chronic Low Back Pain
Pelvic Floor Exercises Versus Swiss Ball Exercises in Patients With Non-Specific Chronic Low Back Pain
This randomized controlled trial aims to compare the effectiveness of pelvic floor muscle exercises and swiss ball exercises in females with non-specific chronic low back pain.
- Trial name
- NCT07610044
- Testing
- Baseline Physiotherapy, Swiss Ball Exercises, Pelvic Floor Muscle Exercises
- Where
- Pakistan
- Volunteers
- 69 people
- Sponsor
- University of Lahore
Total Dose of Bupivacaine Administered During Labor
Dexmedetomidine as an Adjuvant During Dural Puncture Epidural
The study aimed to determine the effects of using varied doses of DEX on the concentration of bupivacaine injected for epidural labor analgesia, and to assess the benefits of the dural puncture epidural.
- Trial name
- NCT07506044
- Testing
- Epidural Catheter with bupivacaine, Epidural with dural puncture, Dexmedetomidine 0.4 added
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Menoufia University
Anesthetics, Local
The Effectiveness of Soft Tissue Vibration in Reducing Pain of Local Anesthesia Injection in Adult Dental Patients
The clinical trial will compare pain perception during dental local anesthesia injections with and without using soft tissue vibration device prior to injection.
- Trial name
- NCT03839134
- Testing
- DentalVibe® Comfort Injection System, Lidocaine Epinephrine
- Where
- Saudi Arabia
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Riyadh Colleges of Dentistry and Pharmacy
Low Back Pain, Mechanical, Symptoms and Signs
Validity and Reliability of the Turkish Version of the Low Back Activity Confidence Scale (Lobacs)
Patients will be recruited from the Outpatient Department of Physical Medicine and Rehabilitation, Kestel State Hospital, who have been diagnosed with mechanical LBP for the past 3 weeks (physical examination, neurological…
- Trial name
- NCT05927909
- Testing
- Low Back Activity Confidence Scale (Lobacs)
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Bursa City Hospital
Knee Pain Chronic, Knee Osteoarthritis
The Effects of Home Use of Transcutaneous Electrical Nerve Stimulation on People With Knee OA and or Chronic Knee Pain
The purpose of the research is to see if the use of transcutaneous electrical nerve stimulation (TENS) at home would reduce knee pain and swelling in people with knee OA and/or chronic knee pain.
- Trial name
- NCT05062499
- Testing
- Active TENS
- Volunteers
- 60 people
- Sponsor
- Omron Healthcare Co., Ltd.
Nonspecific Chronic Low Back Pain
Effectiveness of the Addition of the Kinesio Taping Method to Conventional Physical Therapy Treatment in Patients With Chronic Nonspecific Low Back Pain
The purpose of this study is to determine the effectiveness of the addition of the use of Kinesio Taping in patients with chronic nonspecific low back pain who receive conventional physical therapy.
- Trial name
- NCT01866332
- Testing
- Conventional Physical Therapy, Kinesio Tex Gold ( Kinesiotaping )
- Where
- Brazil
- Volunteers
- 148 people
- Sponsor
- Universidade Cidade de Sao Paulo
Pain
Epidural Morphine Versus Epidural Fentanyl Infusion Following Cesarean Section
For post-Cesarean analgesia, the investigators will compare the efficacy of single-shot epidural preservative free morphine with a continuous epidural fentanyl infusion.
- Trial name
- NCT01362998
- Testing
- Preservative free morphine, Fentanyl
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Goodman, Evan, M.D.
Laparoscopic Gastric Sleeve Surgery, ASA-I and II Risk Class Patients
Mild Intraoperative Hyperventilation to Decrease Post-op. Shoulder Pain After LSG
Shoulder pain is common after laparoscopic surgeries. multiple maneuvers are in use to decrease its incidence with variable results.
- Conditions
- Laparoscopic Gastric Sleeve Surgery, ASA-I and II Risk Class Patients, Same Surgeon
- Trial name
- NCT04514887
- Testing
- mild intraoperative hyperventilation
- Where
- Jordan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Low Back Pain
Effect of Acupuncture and Laser Acupuncture in the Treatment of People With Chronic Nonspecific Low Back Pain.
The aim of this randomized clinical trial will be to compare the efficacy between acupuncture and laser acupuncture on pain and disability in people with chronic nonspecific low back pain .
- Trial name
- NCT05310214
- Testing
- Acupuncture, Laser acupuncture
- Volunteers
- 44 people
- Sponsor
- University of Nove de Julho
Pain, Hispanics
Efficacy of NSAID and Acetaminophen in the Control of Post-Operative Pain in Patients Undergoing Total Knee Replacement
An alternate perioperative pain control protocol composed of intravenous ketorolac and oral acetaminophen for patients who underwent total knee replacement was designed with the aim to determine its efficacy when compared to pain…
- Conditions
- Pain, Hispanics, Opioid Use, Multimodal Analgesia
- Trial name
- NCT05393414
- Testing
- Opioid based protocol, Opioid sparing protocol
- Where
- Puerto Rico
- Volunteers
- 81 people
- Sponsor
- University of Puerto Rico
ITCH
Pain Sensitivity and Pruritus of Peripheral Nerves
Previous research has demonstrated that itch and pain share several underlying neural pathways and signaling molecules. Understanding these common mechanisms is important for developing more effective therapeutic strategies…
- Trial name
- NCT07887906
- Testing
- Mepyramine cream, Histamine Dihydrochloride (HDC), Cowhage (Mucuna Pruriens)
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Aalborg University
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