Clinical trials: Pain Severity
Myofascial Pain Syndrome of Neck
Instrument-Assisted Soft Tissue Mobilization Versus High Power Pain Threshold Ultrasound For Trapezius Myofascial Trigger Points
the purpose of this trial is to compare the effectiveness of instrument-assisted soft tissue mobilization and high power pain threshold ultrasound on pain intensity, pressure pain threshold (PPT), neck range of motion, and neck…
- Trial name
- NCT05288933
- Testing
- Instrument assisted soft tissue mobilization ( IASTM ) and Ultrasound
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Shoulder Pain, Rotator Cuff Related Shoulder Pain
Night Pain Module for Rotator Cuff-Related Shoulder Pain
Night pain is common in people with rotator cuff-related shoulder pain and may disturb sleep and daily life. It may include difficulty falling asleep, waking because of pain, increased pain during the night, difficulty returning…
- Trial name
- NCT07838233
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 275 people
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Migraine
Effects Of Dry Needling On Sternocleidomastoid Muscle For Pain And Disability In Migraine
To determine the effects, sequel of dry needling in migraine by resolving MTrPs in sternocleidomastoid muscle. To determine the possession of dry needling technique to mitigate the frequency, intensity and duration of headache.
- Trial name
- NCT05285852
- Testing
- Dry Needling
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Riphah International University
Needle Fear, Vaccine Hesitancy
Thimble Mindfulness App and Recovery Patch Descriptions
The goal of this clinical trial is to lessen the pain and fear of needles by using a mindfulness-based app and a recovery patch on pediatric patients between the ages of 5 and 11.
- Trial name
- NCT05980247
- Testing
- Thimble Application
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Bianca Edison
Neonatal Tongue-tie, Maternal Nipple Pain Upon Breastfeeding
Use of Topical Benzocaine for Analgesia in Lingual Frenotomy of the Newborn
Frenotomy of tongue-tie is commonly performed to resolve breastfeeding difficulties, eg maternal nipple pain and infant's latching difficulties. The procedure carries minor discomfort for the infants.
- Conditions
- Neonatal Tongue-tie, Maternal Nipple Pain Upon Breastfeeding, Neonatal Latch Difficulties
- Trial name
- NCT01274247
- Testing
- Topical Benzocaine
- Where
- Israel
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Pain, Mobilization
The Effect of Post-Cesarean Section Acupressure on the Severity of Pain and First Mobilization Distance
This randomized controlled trial evaluates the effect of acupressure application on cesareans' pain and the number of steps in the first mobilization.
- Trial name
- Acupress (NCT05311449)
- Testing
- Acupressure, Plasebo acupressure
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Mersin University
Lumbosacral Radiculopathy
Phase 2 Efficacy Trial of Z160 in Lumbosacral Radiculopathy
This study will compare Z160 and placebo in patients with Lumbosacral Radiculopathy for safety and efficacy for a period of 6 weeks.
- Trial name
- NCT01655849
- Testing
- z160
- Where
- 23 sites in United States
- Volunteers
- 141 people
- Sponsor
- Zalicus
Low Back Pain
Walking Away From Back Pain, One Step at a Time
This study will investigate if a 12-week, individually-tailored walking program, using pedometers will be a more clinically and cost-effective option for the management of chronic low back pain than standardized advice and…
- Trial name
- NCT02284958
- Testing
- Standard, Walking
- Where
- Canada
- Volunteers
- 174 people
- Sponsor
- University of Saskatchewan
Healthy Volunteers, Tension-type Headache
A Study to Describe Pain Intensity, Pain Relief and Safety of Neosaldina in the Treatment of Tension-type Headaches (TTH) in Healthy Participants
The purpose of this study is to describe pain relief in TTH with Neosaldina treatment.
- Trial name
- NCT03666858
- Where
- 5 sites in Brazil
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Takeda
Post Operative Pain
Post-Operative Analgesic Efficacy Of Ultrasound Guided Pericapsular Nerve Group Block Versus Combined Suprascapular And Axillary (Circumflex) Nerve Block For Patients Undergoing Shoulder Arthroscopy
Recently, the Combined suprascapular nerve block and axillary nerve block (SSNB+ANB) was proposed to provide anesthesia and postoperative analgesia for shoulder surgery as a safe alternative to interscalene block.
- Trial name
- NCT05791058
- Testing
- ultrasound guided pericapsular nerve group shoulder block, ultrasound guided suprascapular and axillary nerve block, general anesthesia without nerve block
- Volunteers
- 75 people
- Sponsor
- Ain Shams University
Healthy
Characteristics of Different Types of Safety Lancets on Blood Volume and Perceived Pain in Male and Female Volunteers
The study was a randomized, single blind, uni-center pivotal study in male and female healthy volunteers, to determine capillary blood volume and pain perception obtained in a process of puncturing with different safety lancets.
- Trial name
- NCT04001348
- Testing
- Acti-Lance Lite, Acti-Lance Universal, Acti-Lance Special
- Where
- Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- HTL-Strefa S.A.
Low Back Pain, Back Pain
Trial of Inserting Prevalence Information Into Lumbar Spine Imaging Reports
The overall goal of the Lumbar Image Reporting with Epidemiology (LIRE) is to perform a large, pragmatic, cluster randomized controlled trial to determine the effectiveness of a simple, inexpensive and easy to deploy intervention…
- Conditions
- Low Back Pain, Back Pain, Lumbar Pain, Backache
- Trial name
- LIRE (NCT02015455)
- Testing
- Epidemiologic benchmarks included in lumbar imaging reports
- Where
- 4 sites in United States
- Volunteers
- 250,401 people
- Sponsor
- University of Washington
Cesarean Section, Pain
Improving Cesarean Section Experience Through Hypnotherapy
Cesarean section rates continue to increase worldwide, particularly in middle- and high-income countries. In France, the rate has now stabilized around 20 %.
- Conditions
- Cesarean Section, Pain, Anxiety
- Trial name
- NCT02418026
- Testing
- hypnosis
- Volunteers
- 79 people
- Sponsor
- Groupe Hospitalier de la Rochelle Ré Aunis
Peripheral Arterial Disease
Magnesium Oral Supplementation to Reduce Pain Inpatients With Severe Peripheral Arterial Occlusive Disease
Magnesium exerts analgesic effects in several animal pain models and in patients affected by acute postoperative pain and chronic pain of neuropathic origin.
- Trial name
- NCT02455726
- Testing
- Magnesium oxide, Fructose, Oxycodone
- Volunteers
- 150 people
- Sponsor
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Healthy Volunteer Study, Pain Management
A Phase 1 Study of CG001419 Administered Orally in Healthy Subjects
This is a dose finding study of CG001419, administered as a single dose, with or without food, and as multiple doses. CG001419 is being tested in healthy volunteers in this trial with the goal of eventually developing the drug…
- Trial name
- NCT06636500
- Testing
- CG001419
- Where
- Australia
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Cullgen Australia Pty Ltd
Postoperative Pain, Liposomal Bupivacaine
Efficacy of Liposomal Bupivacaine for Transversus Abdominis Plane Block
This is a single-center, randomized, single-blind, parallel-group clinical trial. The study aims to compare the analgesic efficacy of liposomal bupivacaine versus ropivacaine for transversus abdominis plane (TAP) block in…
- Trial name
- NCT07577934
- Testing
- Liposomal Bupivacaine TAP block, Ropivacaine TAP blocks
- Where
- China
- Volunteers
- 86 people
- Sponsor
- Tianjin First Central Hospital
Low Back Pain, Athletic Injuries
Hamstring Viscoelasticity and Low Back Pain
Low back pain (LBP) is a prevalent issue among adolescent rowers, particularly males aged 14 to 16 years, with a high lifetime prevalence (94%) and point prevalence (65%).
- Trial name
- NCT05939609
- Testing
- Ballistic Stretching Exercise, Extender Exercise, Kinesiotaping
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul Nisantasi University
Transgender Persons, Pain Threshold
Perception of Pain During Gender Affirming Hormone Therapy
It is known from the literature that women and men differ in their perception of pain. Why this is the case has not been conclusively clarified. Sex hormones could have a significant influence on this.
- Conditions
- Transgender Persons, Pain Threshold, Perception of Pain, Sex Hormones
- Trial name
- NCT07148921
- Testing
- Quantitative Sensory Testing, Patient Health Questionnaire 9, Hormone concentrations
- Where
- Austria
- Volunteers
- 40 people
- Sponsor
- Medical University of Vienna
Cardiac Surgery
Erector Spinae Plane Block (ESP) vs Serratus Anterior Plane Block (SAP) for Loco-Regional Analgesia in Adult Patients Undergoing Minimally Invasive Cardiac Surgery Via Mini-Thoracotomy: Impact on Morphine Consumption, Pain Control, and Quality of Recovery
Optimization of postoperative analgesia and reduction of opioid consumption are key components of Enhanced Recovery After Surgery (ERAS) protocols in cardiac surgery.
- Trial name
- SAPESP (NCT07433114)
- Testing
- Serratus anterior plane block (SAP), Erector Spinae Plane block (ESP)
- Where
- Italy
- Volunteers
- 57 people
- Sponsor
- Azienda Socio Sanitaria Territoriale Ovest Milanese, Ospedale di Legnano
Bowel Obstruction
A Health Economic Trial in Adult Patients Undergoing Open Colectomy MA402S23B302
This study is designed to compare the standard of care against EXPAREL (bupivacaine liposome extended-release injectable suspension) to determine if total opioid consumption is reduced when using EXPAREL, therefore possibly…
- Trial name
- IMPROVE-Open (NCT01507233)
- Testing
- IV morphine sulfate, EXPAREL (bupivacaine liposome injectable suspension)
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Pacira Pharmaceuticals, Inc
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