Clinical trials: Pain Threshold, active
Dry Needling, Shoulder Pain
Dry Needling and Shoulder Muscle Blood Flow, Motions, and Pain Sensitivity in Individuals with Shoulder Pain
Shoulder pain is one of the most common reasons people consult with their primary health care provider, and 40-50% of these patients with shoulder pain continued to complain of persistent symptoms after 6 to 12 months.
- Trial name
- NCT05596240
- Testing
- Dry Needling
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Texas Woman's University
Fibromyalgia Syndrome
Auricular Acupuncture for Autonomic Balance and Pain in Fibromyalgia
This longitudinal study evaluates the effects of semi-permanent auricular acupuncture on the Autonomic Nervous System (ANS) activity and pressure pain threshold in adult female patients (aged 35-64) diagnosed with Fibromyalgia…
- Trial name
- NCT07641374
- Testing
- The needles will be applied to specific auricular points: Point Zero, Shen Men, Thalamus, and Master Cerebral Point.
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Italian Association for the Research and the Scientific Update
Fibromyalgia, Musculoskeletal Pain
Light Bulb Stimuli to Reduce Chronic Pain
This pilot randomized, double-blind, crossover clinical trial will evaluate the feasibility and preliminary efficacy of chromatic (colored) light exposure for reducing pain severity and pain sensitivity in adults with…
- Trial name
- Light Bulb (NCT07825792)
- Testing
- S-Cone Stimulating Chromatic Light, Equal-Energy White Light
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of North Carolina, Chapel Hill
ITCH
Pain Sensitivity and Pruritus of Peripheral Nerves
Previous research has demonstrated that itch and pain share several underlying neural pathways and signaling molecules. Understanding these common mechanisms is important for developing more effective therapeutic strategies…
- Trial name
- NCT07887906
- Testing
- Mepyramine cream, Histamine Dihydrochloride (HDC), Cowhage (Mucuna Pruriens)
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Primary Dysmenorrhea
Comparison of Pain, Physical, and Psychosocial Parameters in Women With and Without Primary Dysmenorrhea
Dysmenorrhea is a common gynecological condition that negatively affects women's physical, psychological, and social well-being.
- Trial name
- NCT07341685
- Testing
- Observational Assessment
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Izmir Democracy University
Myofascial Pain Syndromes, Myofascial Trigger Point Pain
Kinesio Taping for Upper Trapezius Myofascial Trigger Points
Myofascial pain syndrome is one of the most common causes of musculoskeletal pain, and the upper trapezius is the muscle most frequently affected in the neck and shoulder region.
- Conditions
- Myofascial Pain Syndromes, Myofascial Trigger Point Pain, Neck Pain
- Trial name
- NCT07790042
- Testing
- Kinesio Taping (muscle inhibition technique)
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Pamukkale University
Voluntary
Effectiveness of Neurodynamic Sliding Mobilisation in the "Slump" Position in Relation to the Perceptible Pain Threshold in Asymptomatic People
According to the French National Health Agency, the use of manual therapy techniques is "possible" [grade B] as part of a multimodal combination of treatments for low back pain.
- Trial name
- SPEAKER 2 (NCT06357715)
- Testing
- "slump"position, no" slump" position
- Where
- France
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University Hospital, Rouen
Migraine Disorder, Low Back Pain
Sleep Hygiene Education to Improve Sleep in Chronic Migraine and Back Pain
The goal of this clinical trial is to learn whether sleep hygiene education can improve sleep quality and reduce pain in adults with migraine and/or chronic lower back pain.
- Conditions
- Migraine Disorder, Low Back Pain, Chronic Pain, Sleep Disorder (Disorder)
- Trial name
- NCT07425964
- Testing
- Sleep Hygiene Education
- Volunteers
- 100 people
- Sponsor
- Aalborg University
Cervicogenic Headache, Chronic Neck Pain
Physical Profile of Cervicogenic Headache: Comparison With Neck Pain and Healthy Controls
The goal of this observational study is to compare physical findings across three adult groups. Cervicogenic headache (CGH) is a headache linked to a problem in the neck.
- Trial name
- NCT07776275
- Where
- Turkey (Türkiye)
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Exercise Induced Hypoalgesia, Circadian Rhythm
Pain Perception and Exercise-Induced Hypoalgesia Across Circadian Rhythms
The goal of this randomized crossover clinical trial is to investigate whether exercise-induced hypoalgesia (EIH) is influenced by circadian rhythm in healthy adults aged 18-40 years.
- Conditions
- Exercise Induced Hypoalgesia, Circadian Rhythm, Pain Perception, Healthy Participants
- Trial name
- NCT07290465
- Testing
- High-Intensity Functional Training (HIFT), Supervised Deep Breathing
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Medipol University
Fibromyalgia (FM), Quantitative Sensory Testing
Investigation of Pain Modulation Phenotypes in Female Patients With Fibromyalgia
Fibromyalgia is characterized by altered pain processing, including impaired descending pain inhibition and central sensitization.
- Conditions
- Fibromyalgia (FM), Quantitative Sensory Testing, Central Sensitization, PRESSURE PAIN THRESHOLD
- Trial name
- NCT07640607
- Testing
- Quantitative Sensory Tests(QST) protocol, Clinical Scales
- Volunteers
- 82 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Migraine
Migraine is Associated With Altered Mechanical Pain Sensitivity. This Study Investigates Mechanical Pain Sensitivity, Headache Burden, and Quality of Life in Episodic and Chronic Migraine, Comparing Pressure Algometry and Algopeg® and Assessing Mechanosensitivity of Peripheral Nerves.
Migraine is one of the most prevalent neurological disorders and is associated with a substantial individual and societal burden.
- Trial name
- MechSens_Migra (NCT07559565)
- Testing
- pressure pain algometry
- Where
- Austria
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Bernhard Taxer
Kinesio Taping, Muscle Oxygenation
The Effect of Kinesio Taping Applied to the Gastrocnemius Muscle on Muscle Oxygenation, Pain Pressure Threshold, and Muscle Mechanical Properties
The aim of this study is to investigate the effects of kinesio taping applied to the gastrocnemius muscle on muscle oxygenation, pain pressure threshold, and mechanical properties of the muscle in healthy young individuals.
- Trial name
- NCT07572201
- Testing
- Kinesio® tape application
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Okan University
Healthy
The Effect of Nonverbal Vocalisations on Pain Tolerance
Humans produce non-verbal vocalizations (shouting, growling, screaming), laughter, ...) in various contexts that are likely to perform biological functions. and important social issues.
- Trial name
- VOCPAIN (NCT04425395)
- Testing
- Cold pressor task (CPT), Acoustic Recordings, Index measurement NOL™
- Where
- France
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Healthy Volunteers, Vibration; Adverse Effect
Acute Effects of Smartphone-Delivered Local Vibration on Hand Sensorimotor Performance
This study investigates the acute effects of smartphone-delivered local vibration on hand sensorimotor performance in healthy young adults.
- Trial name
- SmartVib (NCT07521228)
- Testing
- Smartphone Local Vibration at 80 Hz, Smartphone Local Vibration at 150 Hz, Smartphone Local Vibration at 220 Hz
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Post Endodontic Pain, Mechanical Detection Threshold
The Effects of Preemptive Multimodal Analgesic on Endodontic Pain Following Root Canal Therapy.
A clinical trial comparing preemptive multimodal analgesics with placebo in the management of immediate and chronic post-endodontic pain.
- Conditions
- Post Endodontic Pain, Mechanical Detection Threshold, Mechanical Pain Threshold, Mechanical Pain Sensitivity
- Trial name
- NCT07400471
- Testing
- Pregabalin- Acetaminophen, Duloxetine- Acetaminophen
- Where
- Bangladesh
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Chattogram International Dental College
Shoulder Pain
Impact of Different Electrical Frequencies Used in Percutaneous Neuromodulation on Muscle Strength and Pressure Pain Thresholds
Percutaneous electrical nerve stimulation (PENS) involves delivering electrical currents through fine filiform needles inserted near tissues such as muscles, ligaments, or nerves.
- Trial name
- PENS-DOSE (NCT07269925)
- Testing
- Percutaneous electrical nerve stimulation: High frequency, Percutaneous electrical nerve stimulation: Low frequency
- Where
- 2 sites in Poland
- Volunteers
- 30 people
- Sponsor
- Universidad Complutense de Madrid
Tennis Elbow, Health Adult Subjects
Assessment of Pressure Pain Threshold (PPT) and Conditioned Pain Modulation (CPM) After Effect in Patients With and Without Tennis Elbow (TE)
This study at Hashemite University looks at how people with and without tennis elbow (AKA lateral elbow tendinopathy) feel pressure pain and how their bodies briefly "turn down" pain after a cold stimulus.
- Conditions
- Tennis Elbow, Health Adult Subjects, Lateral Elbow Tendinopathy (Tennis Elbow), Pressure Pain Threshold (PPT)
- Trial name
- NCT07178288
- Testing
- Physiological/measurement-validation study
- Where
- Jordan
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- The Hashemite University
Migraine
Puberty, Sex Hormones and Pain Sensitivity in Adolescents With Migraine
The purpose of this research study is to investigate the relationships between sex hormone levels and experimental pain sensitivity and migraine severity will be examined.
- Trial name
- IHS (NCT05738213)
- Testing
- Thermal stimuli, Pressure stimuli, Pain ratings
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
University Students
Pain Prediction Via Machine Learning: Electrical Thresholds and Interoception
The goal of this observational study is to predict (retrospective and prospective) musculoskeletal pain in university students using machine learning models based on electrical threshold measurements and interoceptive awareness.
- Trial name
- NCT07839520
- Testing
- No Intervention: Observational Cohort
- Where
- Turkey (Türkiye)
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- Amasya University