Clinical trials: Pain Tolerance
Pain, Inflammatory Response
Association Between Body Composition and Pain in Spinal Cord Injury
The purposes of the study are to quantify and compare relationships among acute changes in inflammatory markers and evoked pain sensitivity after a high-fat meal (HFM) challenge, compared to a moderate-fat meal challenge, and…
- Trial name
- NCT05459207
- Testing
- Moderate Fat Meal, High Fat Meal
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Miami
Low Back Pain
Kettlebell Swings & Low Back Pressure Pain Threshold
The purpose of this study is to determine whether a high intensity kettlebell workout, utilizing a Tabata protocol format, can decrease objective measures of pain pressure threshold in subjects without low back pain.
- Trial name
- NCT03696615
- Testing
- Tabata Kettlebell Swing Workout, Control
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Central Florida
Pain
Validation of the Turkish Version of the Pain Sensitivity Questionnaire
The Pain Sensitivity Questionnaire(PSQ) is a self-rating measure for the assessment of pain sensitivity and has been developed by Dr. R. Ruscheweyh in Germany.
- Trial name
- NCT03609788
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Istanbul Medeniyet University
Myofascial Pain Syndromes, Myofascial Trigger Point Pain
Kinesio Taping for Upper Trapezius Myofascial Trigger Points
Myofascial pain syndrome is one of the most common causes of musculoskeletal pain, and the upper trapezius is the muscle most frequently affected in the neck and shoulder region.
- Conditions
- Myofascial Pain Syndromes, Myofascial Trigger Point Pain, Neck Pain
- Trial name
- NCT07790042
- Testing
- Kinesio Taping (muscle inhibition technique)
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Pamukkale University
Pain Thresholds
Does Boredom With Simultaneously Perceived Pain Affect Pressure Pain Thresholds
The purpose of this study is to investigate if different emotional states such as boredom and happiness could influence mechanical pain thresholds and other pain - related variables such as pain tolerance, pain intensity and pain…
- Trial name
- BPPPT (NCT07330167)
- Testing
- Boredom intervention, Humorous
- Where
- Sweden
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Linnaeus University
Hamstring Tightness
IASTM vs. Static Stretching for Hamstring Tightness: Short- and Long-Term Effects
This study compares two treatments for people with tight hamstring muscles (the muscles at the back of the thigh): instrument-assisted soft tissue mobilization (IASTM) and static stretching.
- Trial name
- IASTM-HT (NCT07838844)
- Testing
- Instrument-Assisted Soft Tissue Mobilization, Static Stretching
- Volunteers
- 46 people
- Sponsor
- GÖKHAN MARAŞ
Knee Arthritis, Hip Arthritis
Preoperative Pain Threshold and Rapid Recover Programs
To investigate the association between grip strength and preoperative pain threshold as measured by pressure algometer and validated pain outcome surveys.
- Trial name
- NCT02740738
- Testing
- Wagner Pain Algometer, Dynamometer
- Where
- United States
- Volunteers
- 201 people
- Sponsor
- Duke University
Pain Threshold, Pain Tolerance
Acute Effects of LLLT on Pain Threshold and Pain Tolerance
Pain is defined by the International Association for the Study of Pain as "an unpleasant sensory and emotional experience associated with, or resembling that associated with, actual or potential tissue damage." Low-Level Laser…
- Conditions
- Pain Threshold, Pain Tolerance, Acute Pain, Low-level Laser Therapy
- Trial name
- NCT07422272
- Testing
- Low-Level Laser Therapy (LLLT)
- Where
- Cyprus
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- European University of Lefke
Ectopic Pregnancy
The Effect of Subclinical Dose of Ketamine on Early Postoperative Pain Sensitivity in Patients Undergoing Salpingectomy
The experiment aims to explore the clinical effect of subclinical doses of ketamine on early postoperative pain sensitivity in ectopic pregnancy population.
- Trial name
- NCT06559280
- Testing
- esketamine
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Fujian Provincial Hospital
Tension-Type Headache
Efficacy of Kinesio Taping in Tension Type Headache
Aim: The purpose of this study was to investigate the efficacy of Kinesio taping on upper trapezius muscle on the reduction of pain and emotional state in the treatment of patients with tension type headache by acting on…
- Trial name
- NCT03665142
- Testing
- Kinesio taping, Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 71 people
- Sponsor
- Istanbul Bilgi University
Pain
Hypoalgesic Effect of Electrical Current and Cervical Manipulation
This study evaluates the hypoalgesic effect of the TENS application associated with joint manipulation of the cervical region in healthy individuals.
- Trial name
- NCT03531541
- Testing
- Application of TENS, CJM
- Where
- 2 sites in Brazil
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Sao Carlos
Irritable Bowel Syndrome
Ethosuximide to Treat IBS
Abdominal pain remains the most deleterious symptom for patients with irritable bowel syndrome (IBS) and is causing a significant alteration of their quality of life.
- Trial name
- IBSET (NCT02973542)
- Testing
- Ethosuximide
- Where
- France
- Volunteers
- 162 people
- Sponsor
- University Hospital, Clermont-Ferrand
Myofascial Pain of Upper Trapezius Muscle
The Efficacy of Thread Embedding Acupuncture on Pain Score, Neck Disability Index, and Pressure Pain Threshold for Myofascial Pain Therapy in the Upper Trapezius Muscle
Myofascial pain is characterized by myofascial trigger points, considered as a major cause of neck and shoulder pain in the working population.
- Trial name
- NCT05987683
- Where
- 2 sites in Indonesia
- Volunteers
- 44 people
- Sponsor
- Universitas Indonesia
Pain Threshold, Surgery
The Effect of Remifentanil on the Objectively Measured Pressure Pain Threshold
It is a clinical study investigating the relationship between objectively measured pain threshold and the need for escalating doses of remifentanyl opioids. This study is expected to include approximately 40 participants.
- Conditions
- Pain Threshold, Surgery, Postoperative Pain, Intravenous Anesthesia
- Trial name
- NCT07568405
- Testing
- Pressure pain theshold measured under remifentanil (ultiva®) infusion, Postoperative PCA IV morphine (Sterop®) consumption and adverse events history
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Université Libre de Bruxelles
Stable Angina Pectoris
Efficacy of Extracorporeal Shockwave Myocardial Revascularization Therapy in Patients With Stable Angina Pectoris
Low intensity shockwaves have been proven in animal and pilot clinical studies to induce local growth of new blood vessels. Small single-center clinical trials with shockwave therapy showed promising results in reducing angina…
- Trial name
- NCT02339454
- Testing
- Active treatment group
- Where
- 2 sites in Lithuania, Russia
- Volunteers
- 72 people
- Sponsor
- Evgeny Shkolnik, MD
Hematological Malignancies
Impact of Child Positioning on Pain During a Lumbar Puncture
This protocol is a pilot study on standard care. The main goal is to assess the impact of positioning on lumbar puncture process especially on pain sensitivity in children.
- Trial name
- PHIPA-PEPL (NCT02834156)
- Testing
- LP in a seated position then LP in a lying position, LP in a lying position then LP in a seated position
- Where
- France
- Volunteers
- 28 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Pain Threshold, Low Back Pain
Relationship Between Pressure Pain Threshold and Pain Intensity, Affect and Disability in CLBP
The association between pressure pain threshold and different aspects of low back pain has garnered attention over the years. However, since most of such studies in the past employed cross sectional designs, a longitudinal study…
- Conditions
- Pain Threshold, Low Back Pain, Pain Measurement
- Trial name
- NCT04482075
- Testing
- segmental stability training
- Where
- Pakistan
- Volunteers
- 41 people
- Sponsor
- Dow University of Health Sciences
Intellectual Disability
Characterization of Nociception Phenotype in Individuals With Intellectual Disability
Background: People with intellectual disability (ID) often have physical disabilities as well. These physical problems can affect their bones, muscles, nerves, and gastrointestinal tracts. All of these issues can also cause pain.
- Trial name
- NCT05473429
- Testing
- TSA2 Thermosensory Stimulator
- Where
- United States
- Volunteers
- 215 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Low Back Pain, Pain, Chronic
What Determines a Positive Outcome of Spinal Manipulation for Persistent Low Back Pain: Stiffness or Pain Sensitivity? A Randomized Trial
Introduction Several treatment methods have been proposed to ease the burden of low back pain (LBP) but none are clearly superior.
- Trial name
- POPS (NCT04086667)
- Testing
- Spinal manipulation
- Where
- Denmark
- Volunteers
- 132 people
- Sponsor
- Spine Centre of Southern Denmark
Neck Pain, Migraine
Common Pain Mechanisms in Migraine, Migraine-Related Neck Pain, and Lower Back Pain: A Cross Sectional Study
Migraine is one of the primary headache disorders with a high prevalence worldwide, leading to significant disability and reduced quality of life.
- Conditions
- Neck Pain, Migraine, Low Back Pain
- Trial name
- NCT07567300
- Where
- Turkey (Türkiye)
- Volunteers
- 179 people
- Sponsor
- Bozok University