Clinical trials: Painful
Lumbar Spine Degeneration, Physical Activity
Physical Activity, Disability and Quality of Life Before and After Lumbar Spine Surgery
To date it is unknown how physical activity levels in adults is limited before and after lumbar spine surgery and if physical activity level is associated with disability and limitations of quality of life.
- Conditions
- Lumbar Spine Degeneration, Physical Activity, Quality of Life, Disability Physical
- Trial name
- PA-LSS (NCT03452449)
- Testing
- planned lumbar spine surgery
- Where
- 2 sites in Switzerland
- Volunteers
- 29 people
- Sponsor
- University Hospital, Basel, Switzerland
Chronic Pain, Opioid Use Disorder
Virtual Reality for Chronic Pain and Opioid Use Disorder Pilot
This is a pilot feasibility study of a virtual reality device for patients with co-morbid chronic pain and opioid use disorder.
- Trial name
- NCT05546749
- Testing
- RelieVRx
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Albert Einstein College of Medicine
Temporomandibular Disorder, Myofascial Pain
Manual Therapy and Splint Therapy in Patients With Temporomandibular Dysfunction
The aim of this study was to compare the efficacy of splint treatment and manual therapy in patients diagnosed with myofascial temporomandibular dysfunction with bruxism.
- Conditions
- Temporomandibular Disorder, Myofascial Pain, Bruxism
- Trial name
- NCT05352438
- Testing
- Manual Therapy Group, Splint Therapy Group
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Turkoglu Dr. Kemal Beyazit State Hospital
Cervical Radiculopathy
Effects of DRT on Neck Pain, ROM, and Chest Expansion in Patients With CR
This randomized controlled trial aims to determine the effects of the diaphragmatic release technique on neck pain, cervical range of motion, and chest expansion in patients with cervical radiculopathy.
- Trial name
- NCT07628348
- Testing
- Diaphragmatic Release Technique, Traditional Physical Therapy
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Riphah International University
Pain, Postoperative, Anesthesia, Local
Postoperative Analgesia in Laparoscopic Abdominal Surgery After Exparel Via TAP or Local Infiltration
This study evaluates differences in how administering liposomal bupivacaine via two different methods affects postoperative pain control in laparoscopic abdominal surgery patients.
- Conditions
- Pain, Postoperative, Anesthesia, Local, Anesthesia; Functional, Anesthesia
- Trial name
- NCT03927326
- Testing
- Exparel 266 MG Per 20 ML Injection
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Washington
Physical Fittness
Effect of Mulligan'Mobilization With Movement on Pain, Disability and Range of Motion in Patients With Knee Osteoarthritis
we tested the effect of adding the mobilization with movement to the traditional physical therapy program on pain, ROM and functional disability in patients with knee OA.
- Trial name
- NCT01756378
- Testing
- joint mobilization with movement, traditional physical therapy program
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Neuralgia, Chronic Pain
Botulinum Toxin for Chronic Neuropathic Pain
Treatment of peripheral neuropathic pain with Botulinum Toxin (BoNT) has showed promising results since the first study was released in 2001.
- Trial name
- NCT06036043
- Testing
- Botulinum toxin type A
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- Region Zealand
Pain
Study of the Effectiveness and Tolerability of OROS Hydromorphone HCI SR(Slow-release) Tablets and Immediate-Release Hydromorphone Tablets in Patients With Chronic Pain
The purpose of this study was to characterize a safe and effective means of conversion and titration to an appropriate dose of hydromorphone HCI, to demonstrate comparable efficacy of OROS hydromorphone HCI SR (slow release) and…
- Trial name
- NCT00410943
- Testing
- OROS Hydromorphone HCI SR (slow release)
- Volunteers
- 169 people
- Sponsor
- Alza Corporation, DE, USA
Coronary Syndrome, Acute, Coronary Artery Disease
A Study of Population and Sex-specific Troponin Cutoffs for Ruling Out Acute Myocardial Infarction
Acute myocardial infarction (MI) is defined as a rise and/or fall in cardiac troponins (cTn) with at least one value above the 99th percentile upper reference limit (URL) in the context of symptoms or clinical evidence of…
- Conditions
- Coronary Syndrome, Acute, Coronary Artery Disease, Myocardial Infarction
- Trial name
- DANSPOT (NCT05336435)
- Testing
- Implementation of the new population and sex-specific 99th percentile URL for cardiac troponin
- Where
- 22 sites in Denmark
- Volunteers
- 5,175 people, healthy volunteers welcome
- Sponsor
- Herlev Hospital
Postoperative Pain
Can the Different Instruments Used ın Root Canal Treatment Have an Effect on Postoperative Pain?
Root canal treatment is a treatment method in which the pulp is irreversibly infected due to caries or trauma or when the pulp loses its vitality.
- Trial name
- NCT05927025
- Testing
- Hand K-files
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Epidermylosis Bullosa
Randomised Double Blind Placebo Controlled Cross Over Design of the Efficacy of Topical Morphine for Inflammatory Pain in Children With Epidermolysis Bullosa
Randomised Double blind placebo controlled cross over design study of the efficacy of morphine for inflammatory pain in children with Epidermolysis Bullosa
- Trial name
- NCT00231517
- Testing
- topical opiod, morphine sulphate in intrasite gel
- Where
- United Kingdom
- Sponsor
- Institute of Child Health
Acute Pain
A Phase 2 Study to Evaluate Analgesic Effect of IV CR845 For Pain Following Bunionectomy Surgery
This is a single-center, randomized, double blind, placebo controlled, parallel group proof of concept study to evaluate the analgesic efficacy as well as the safety, tolerability and pharmacokinetic profile of CR845 in patients…
- Trial name
- NCT01789476
- Testing
- CR845
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Cara Therapeutics, Inc.
Osteoarthritis, Knee
Comparison of Effectiveness of Two Different Electrotherapy Agents on Central Sensitization
The aim of this study is to compare the efficacy of transcutaneous electrical nerve stimulation (TENS), interferential currents (IFCs) and sham devices in improving central sensitization (CS) findings, including pressure pain…
- Trial name
- NCT04153825
- Testing
- Transcutaneous Electrical Nerve Stimulation, Interferential Current, Hydrocollator hot-pack
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Turkish League Against Rheumatism
Shoulder Pain, Shoulder Injuries
SPR PNS for Chronic Shoulder Pain
The purpose of this research is to gather post-market data regarding the effectiveness of the SPRINT Peripheral Nerve Stimulation (PNS) System for the treatment of chronic shoulder pain due to chronic degenerative changes of your…
- Conditions
- Shoulder Pain, Shoulder Injuries, Shoulder Arthritis
- Trial name
- NCT05649917
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- International Spine, Pain and Performance Center
Rehabilitation, Aging Problems
Plantar Fasciitis Management on Postural Control
Foot pain is common in the general population. Plantar fasciopathy may affect 7% of the population at some time in their lives, but the incidence increases with age.
- Conditions
- Rehabilitation, Aging Problems, Foot Diseases, Mobility Limitation
- Trial name
- NCT06172517
- Testing
- Orthosis intervention
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- Université du Québec à Chicoutimi
Pain Control
Comparison of Low-cost Interventions for Pain Reduction During Radial Artery Puncture in the Emergency Department: A Three-arm Randomized Controlled Trial
The objective of this clinical trial is to investigate if local anesthesia using topical analgesic drug (10% lidocaine spray) or cryo-analgesic (Ice pack) can reduce pain levels during and after arterial blood sampling procedure.
- Trial name
- NCT06505889
- Testing
- Local anesthesia methods
- Where
- Thailand
- Volunteers
- 126 people
- Sponsor
- Queen Savang Vadhana Memorial Hospital, Thailand
Balneology, Whole Body Vibration
Whole-Body Vibration and Balneotherapy in Chronic Low Back Pain
This randomized controlled clinical trial aims to investigate the effects of whole-body vibration (WBV) exercises combined with balneotherapy on pain, physical function, sleep quality, and daily activity levels in individuals…
- Conditions
- Balneology, Whole Body Vibration, Water, Exercise
- Trial name
- Whole-Body Vib (NCT07067489)
- Testing
- Balneotherapy, Whole-Body Vibration Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Uludag University
Chronic Pain Syndrome, Sensitization, Central
Management of Chronic Non-Cancer Pain With Non-Pharmacological Therapies
A randomized controlled clinical trial will be conducted, involving a psychoeducational activity as the intervention. There will be a control group of patients with non-cancer chronic pain who will continue their usual treatment.
- Conditions
- Chronic Pain Syndrome, Sensitization, Central, Quality of Life, Patient Empowerment
- Trial name
- NCT06440668
- Testing
- Chronic Pain Management Workshop with Non-Pharmacological Therapies
- Where
- Spain
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Hospital San Juan de Dios del Aljarafe de Sevilla
Myocardial Infarction, Angina, Unstable
Using Magnetic Resonance Imaging to Evaluate Heart Vessel Function After Angioplasty or Stent Placement Procedures
Coronary artery disease (CAD) is caused by a narrowing of the blood vessels that supply blood and oxygen to the heart. Balloon angioplasty and stent placement are two treatment options for people with reduced heart function…
- Conditions
- Myocardial Infarction, Angina, Unstable, Cardiomyopathy, Hypertrophic
- Trial name
- NCT00692991
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- Johns Hopkins University
Menopausal Symptoms
A Clinical Trial on the Efficacy of a Combination Herbal Product, Biotropics' Nu Femme, on Menopausal Symptoms and Quality of Life in Women
The purpose of this study is to assess the effectiveness of an herbal combination product called Nu Femme, on menopausal symptoms in peri-menopausal women.
- Trial name
- 14NMHB (NCT02269891)
- Testing
- Nu Femme
- Where
- 4 sites in Canada
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- KGK Science Inc.
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.