Clinical trials: Painful
Cannabis Use, Cannabis Use, Unspecified
Cannabis and Cancer, an Online Training for Oncology Nurses
The purpose of this study is to evaluate the preliminary effects and impacts of a digital educational intervention to support nurses' professional practice regarding safe cannabis use by young adults (18-39 years) diagnosed with…
- Conditions
- Cannabis Use, Cannabis Use, Unspecified, Nurse's Role, Oncology Pain
- Trial name
- NCT05663346
- Testing
- Cannabis & Cancer digital educational intervention, Standard information regarding cannabis use in oncology
- Where
- Canada
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Chronic Low-back Pain
Virtual Reality Integrated Within Physiotherapy for Patients With Complex Chronic Low Back Pain
This study examines the effect of a 12-week intervention of physiotherapy with integrated Virtual Reality (VR) on 120 patients with complex chronic low back pain.
- Trial name
- VARIETY (NCT05701891)
- Testing
- Physiotherapy with integrated Virtual Reality, Physiotherapy (usual care)
- Where
- Netherlands
- Volunteers
- 120 people
- Sponsor
- HAN University of Applied Sciences
Migraine
Study to Evaluate the Efficacy and Safety of Erenumab (AMG 334) in Migraine Prevention
A study to evaluate the effect of erenumab compared to placebo on the change from baseline in monthly migraine days in participants with episodic migraine.
- Trial name
- NCT01952574
- Testing
- Erenumab, Erenumab PFS, Erenumab AI/Pen
- Where
- 66 sites in United States, Canada and 5 more
- Volunteers
- 483 people
- Sponsor
- Amgen
Dental Anxiety, Pain
Effectiveness of Hand/Eyes/Mouth Behavior Management Technique During Local Anesthesia in Preschool Children
This will be a randomized, controlled, parallel-group clinical trial. The aim of this studio will be to evaluate the effectiveness of "Hands/Eyes/mouth" behavior management technique versus a conventional technique (covering the…
- Conditions
- Dental Anxiety, Pain, Infant Behavior, Heart Rate and Rhythm Disorders
- Trial name
- NCT02591797
- Testing
- inferior alveolar and lingual nerve block procedure
- Where
- Spain
- Volunteers
- 52 people
- Sponsor
- Cardenal Herrera University
Diabetic Peripheral Neuropathic Pain
Evaluation of Efficacy and Safety of VX-993 for Pain Associated With Diabetic Peripheral Neuropathy
The purpose of this study is to evaluate the efficacy, safety, and tolerability of VX-993 in participants with pain associated with Diabetic Peripheral Neuropathy (DPN)
- Trial name
- NCT06619860
- Testing
- VX-993, Pregabalin
- Where
- 47 sites in United States, Canada and 4 more
- Volunteers
- 300 people
- Sponsor
- Vertex Pharmaceuticals Incorporated
Pain
Europain®: A Study of Procedural Pain
Pain associated with procedures performed on adult ICU patients is ubiquitous and the subject of research attention.While there is growing evidence about the prevalence, characteristics and measurement of procedural pain in ICUs…
- Trial name
- Europain® (NCT01070082)
- Where
- France
- Volunteers
- 5,150 people
- Sponsor
- Saint-Louis Hospital, Paris, France
Ibuprofen, Nonsteroidal Anti-inflammatory Drug
A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial of Intravenous Ibuprofen 400 and 800 mg Every 6 Hours in the Management of Postoperative Pain.
This study was to evaluate the efficacy and safety of intravenously administered ibuprofen 400mg and 800 mg q6h for the management of moderate to severe postoperative pain in Chinese population.
- Conditions
- Ibuprofen, Nonsteroidal Anti-inflammatory Drug, Intravenous, Injectable
- Trial name
- NCT04429282
- Testing
- ibuprofen
- Where
- China
- Volunteers
- 396 people
- Sponsor
- Yi Feng, MD
Low Testosterone, Hypogonadism
Testosterone and Pain Sensitivity
This research is being done to see whether testosterone replacement in men who take opioid-based pain medications and have low testosterone levels will show improvement in pain tolerance, pain perception and quality of life.
- Conditions
- Low Testosterone, Hypogonadism, Pain
- Trial name
- NCT01689896
- Testing
- Testosterone Gel
- Where
- United States
- Sponsor
- Johns Hopkins University
Osteoarthritis, Knee, Arthroscopy
Evaluating the Effectiveness of Subchondroplasty for Treating Bone Marrow Lesions of the Knee
The primary objective of this randomized pilot study is to evaluate whether subchondroplasty combined with knee arthroscopy is more effective at reducing knee pain and improving knee function compared to knee arthroscopy alone.
- Conditions
- Osteoarthritis, Knee, Arthroscopy, Musculoskeletal Disease, Bone Marrow Edema
- Trial name
- NCT03699046
- Testing
- Subchondroplasty and Knee Arthroscopy, Knee Arthroscopy Alone, Subchondroplasty
- Where
- Canada
- Volunteers
- 18 people
- Sponsor
- University of Calgary
Myocardial Ischemia
MCG for Non-Obstructive Myocardial Ischemia
The aim of this prospective study is to identify Non-Obstructive Myocardial Ischemia of patients who have acute chest pain using Magnetocardiography.
- Trial name
- NCT07657546
- Testing
- Magnetocardiography
- Where
- China
- Volunteers
- 3,786 people
- Sponsor
- Qilu Hospital of Shandong University
Migraine
Multimodal Physiotherapy Intervention for People With Migraine
Migraine is one of the most prevalent primary headache disorders worldwide and is associated with substantial impairments in quality of life, work productivity, and psychosocial functioning.
- Trial name
- NCT07671703
- Testing
- Multimodal Treatment Program, Usual Care
- Where
- Germany
- Volunteers
- 195 people
- Sponsor
- Hochschule Osnabruck
Postoperative Pain
Efficacy of Ultrasound Guided Rectus Sheath Block on Post Operative Quality of Recovery
Effective Postoperative pain management following laparotomy represents a cornerstone in the care of surgical patients. With the growing utilization of Enhanced recovery after surgery protocols (ERAS), a paradigm shift in…
- Trial name
- NCT05244746
- Testing
- rectus sheath block
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Kasr El Aini Hospital
Scheduled Cardiac Surgery, Sternotomy
Postoperative Rehabilitation After Cardiac Surgery in Patients at Risk of Respiratory Complications. Effects of a Continuous Bi-laterosternal Infusion of Ropivacaine Through Multihole Catheters
Postoperative pain after cardiac surgery is a risk factor for postoperative complications. In cardiac surgery, pain is more intense during the first 48 hours and disturbs the patient's capacity of coughing, deep breathing, and…
- Conditions
- Scheduled Cardiac Surgery, Sternotomy, Elderly Patients, Obesity
- Trial name
- BLS-Sterno (NCT01828788)
- Testing
- Ropivacaine
- Where
- France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Clermont-Ferrand
High-grade Partial or Full Thickness Rotator Cuff Tears
Cold and Compression After Rotator Cuff Repair (RCR)
The purpose of this study is to compare pain score (Patient-Reported Outcomes Measurement Information System: PROMIS NRS Pain Subscale) between the control and cold/compression groups pre-surgically, daily after surgery for 14…
- Trial name
- NCT07516327
- Testing
- SOC (Standard of care), Cold and Compression
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Ochsner Health System
Pain
Quality of Life With Arcoxia in Women With Dysmenorrhea (0663-094)
Allow gynecologists to gain experience with arcoxia for treatment of dysmenorrhea.
- Trial name
- NCT00380627
- Testing
- MK0663, Arcoxia, etoricoxib / Duration of Treatment: 3 Days
- Volunteers
- 337 people
- Sponsor
- Organon and Co
Caesarean Section, Pain, Acute
Subarachnoid Block With Ultrasound-Guided Transversalis Fascia Plane Block for Cesarean Section
Postoperative pain management is critical for the fulfillment of the maternal duties. The transversalis fascia plane (TFP) block provides adequate postoperative analgesia in the T12 and L1 dermatomes.
- Trial name
- NCT04172727
- Testing
- Bupivacaine Hcl 0.25% Inj, saline 0.9%
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Rotator Cuff Tears
Photobiomodulation Laser Therapy Following Arthroscopic Rotator Cuff Repair
Rehabilitation following rotator cuff surgery is characterized with high levels of pain, limited range of motion, and decreased quality of life.
- Trial name
- LLL&RotC01 (NCT04593342)
- Testing
- B-Cure Pro
- Where
- Israel
- Volunteers
- 53 people
- Sponsor
- Erika Carmel ltd
Postoperative Pain
Postoperative Pain Management for Hip Surgeries: UltrasoundGuided Suprainguinal Fascia Iliaca Compartment Block Versus Suprainguinal Fascia Iliaca Compartment Block in Combination With Sciatic Nerve Block
The aim of the Study is to compare the analgesic efficacy and clinical outcomes of suprainguinal fascia iliaca block (SIFIB) alone versus SIFIB combined with sciatic nerve block (SNB) in patients undergoing hip surgery.
- Trial name
- NCT07787442
- Testing
- Bupivacaine injection
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Ain Shams University
Low Back Pain
Additional Effect of Pain Neuroscience Education to Spinal Manipulative Therapy in Chronic Low Back Pain
Objectives: The primary objective will be to investigate the additional effect (immediate and after one-month follow up) of pain neuroscience education (PNE) to Spinal Manipulative Therapy (SMT) on primary outcomes of pain…
- Trial name
- NCT03356886
- Testing
- Spinal Manipulative Technique, Pain Neuroscience Education
- Where
- Brazil
- Volunteers
- 104 people
- Sponsor
- University of Sao Paulo
Work-Related Condition, Musculoskeletal Health
Relationship Between Neck Posture and Stiffness of Head and Neck Muscles, Pain and Proprioception in Desk Workers
In our study, posture in desk workers; it aims to evaluate the relationship between cervical range of motion, proprioception, muscle stiffness, posture and pain.
- Trial name
- NCT06012773
- Where
- Turkey (Türkiye)
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Pınar Kuyulu
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