Clinical trials: Painful
Plantar Fasciopathy
Efficacy of a Self-managed Versus a Predetermined Resistance Training Protocol in Reducing Pain in Individuals With Plantar Fasciopathy
The purpose of this trial is to investigate whether a self-managed resistance training protocol is more effective than a predetermined resistance training protocol in improving the Foot Health Status Questionnaire pain domain…
- Trial name
- NCT03304353
- Testing
- Self-managed protocol, Predetermined protocol
- Where
- Denmark
- Volunteers
- 70 people
- Sponsor
- Aalborg University
Pain, Aromatherapy
The Effect of Aromatherapy on the Insulin Injection Pain
Needle phobia occurs in more than half of diabetic patients due to the pain caused by frequent insulin injection. Therefore, this study evaluated the effect of topically administered lavender aromatherapy on the pain of insulin…
- Conditions
- Pain, Aromatherapy, Subcutaneous Injections
- Trial name
- NCT04767737
- Testing
- Topically Administered Lavender Aromatherapy, Topically Administered Water
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Coronary Artery Disease, Pain
Study of Ranexa in Patients With Coronary Artery Disease and Painful Polyneuropathy
This study was to determine whether ranolazine was effective in the treatment of neuropathic pain in patients with coronary artery disease.
- Conditions
- Coronary Artery Disease, Pain, Peripheral Nervous System Diseases, Polyneuropathy
- Trial name
- NCT00832572
- Testing
- Ranolazine
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Gilead Sciences
Analgesia, Patient-Controlled
Tailored PCA Based on Preoperative Pain Sensitivity
Opioids via intravenous patient-controlled analgesia (IV PCA) are widely used for postoperative pain control. However, effective pain control with minimized side effects of analgesic agents is still challenging.
- Trial name
- NCT03252977
- Testing
- Tailored regimen of IV PCA according to pain sensitivity, Regimen of IV PCA without considering pain sensitivity
- Where
- South Korea
- Volunteers
- 118 people
- Sponsor
- Seoul National University Hospital
Inguinal Hernia, Femoral Hernia
Laparoscopic Inguinal and Femoral heRniA rePaIr Using Pre-shapeD 4DMESH® (4DLap)
The purpose of this study is to evaluate the safety and performance of the 4DMESH® used in (robot-assisted) laparoscopic inguinal and femoral hernia repair.
- Trial name
- NCT05306496
- Testing
- Pre-shaped 4DMESH®
- Where
- 9 sites in Belgium, France and 1 more
- Volunteers
- 196 people
- Sponsor
- Cousin Biotech
Low Back Pain, Quality of Life
Low Back Pain and Quality of Life Among the Ambulance Drivers in Malaysia's Hospitals
The study is a community interventional study by using an integrated back pain module (IBPM). The purpose of this study is to find out if the module training has any benefit on Low Back pain among ambulance drivers.
- Trial name
- NCT04824846
- Testing
- Integrated back pain module (IBPM), Health Educational Pamphlet.
- Where
- Malaysia
- Volunteers
- 198 people
- Sponsor
- Universiti Sains Malaysia
Acute Chest Pain, Acute Coronary Syndrome
Prognostic Value of Cardiovascular Risk of sST2 and Troponin I-hs in Patients With Acute Chest Pain
The role of the sST2 biomarker has been widely explored in heart failure, so much so that it was included in the AHA guidelines in 2013 and 2017.
- Trial name
- sST2 (NCT05752188)
- Testing
- Multimarker approach in acute coronary syndrome
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Acute Postoperative Pain, Chronic Postoperative Pain
Comparison of the Efficacy and Safety of Intravenous Buprenorphine Administered Via PCA System Versus Oxycodone in the Management of Postoperative Pain After Video-Assisted Thoracoscopic Surgery
The goal of this clinical trial is to learn whether intravenous buprenorphine administered via a patient-controlled analgesia (PCA) system provides effective and safer postoperative pain control than intravenous oxycodone PCA in…
- Conditions
- Acute Postoperative Pain, Chronic Postoperative Pain, Toracosurgery, Video-assisted Thoracis Surgery (VATS)
- Trial name
- NCT07434427
- Testing
- Group B (Buprenorphine), Group O (Oxycodone)
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- Medical University of Silesia
Pain, Ankle Injuries
Erector Spinae Plane Block and Ankle and Foot Surgery
Regional anesthesia is commonly used in orthopedic and surgical procedures in ankle and foot surgery to manage pain. The ultrasound-guided nerve block is a safe and effective regional anesthesia technique that provides effective…
- Trial name
- NCT05708742
- Testing
- Ultrasound, Bupivacaine Hydrochloride, saline solution
- Where
- Egypt
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Fayoum University Hospital
Interstitial Cystitis, Painful Bladder Syndrome
Bladder Thermal Distention for Patients With Interstitial Cystitis / Painful Bladder Syndrome
Patients with Interstitial Cystitis / PBS will be treated with bladder thermal distention (BTD).
- Trial name
- IC (NCT01838486)
- Testing
- Bladder Thermal Distention
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Assaf-Harofeh Medical Center
Laparoscopic Cholecystectomy, Pain
ICOUGH Bundle and Postoperative Pain and Nausea After Laparoscopic Cholecystectomy
This study will use a randomized controlled experimental research design. The population of the study will consist of all adult patients who undergo laparoscopic cholecystectomy at the General Surgery Clinic of Atatürk University…
- Conditions
- Laparoscopic Cholecystectomy, Pain, ICOUGH, NAUSEA
- Trial name
- ICOUGHBundle (NCT06755970)
- Testing
- ICOUGH
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Myofascial Pain Syndrome - Neck
Comparing Physical Therapy Interventions on Craniovertebral Angle (CVA) in Cervical Myofascial Pain Syndrome (MPS)
Myofascial pain syndrome (MPS) and radiculopathy are prevalent musculoskeletal conditions that afflict a substantial portion of the population, causing significant discomfort and impairments in daily functioning.
- Trial name
- NCT07098754
- Testing
- Dry Needling, Trigger point therapy, Maitlands' Mobilizations
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- National Orthopedic and General Hospital
Migraine
To Evaluate the Blockade of CGRP in Preventing PACAP-38 Induced Migraine-like Attacks With AMG 334 in Migraine Patients
Phase I, Randomized, Parallel-group, Double-Blind, Placebo-Controlled, Single Dose Study to Evaluate the Blockade of CGRP Receptor by AMG 334 in Preventing PACAP-38 Induced Migraine-like Attacks in Migraine Patients.
- Trial name
- NCT02542605
- Testing
- Erenumab, PACAP-38 Challenge Agent
- Where
- 3 sites in United States, Belgium and 1 more
- Volunteers
- 35 people
- Sponsor
- Amgen
Postoperative Pain
Comparison of the Efficacy of PENG Block in Combination With LFCN Block and Wound Infiltration
The ultrasound-guided approach for the blockade of articular branches of femoral and obturator nerves, pericapsular nerve group (PENG) block, is an effective method for postoperative analgesia in hip surgeries.
- Trial name
- NCT04681222
- Testing
- LFCN, Wound infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people
- Sponsor
- Derince Training and Research Hospital
Low Back Pain, Postural
Effect of Global Postural Reeducation on Low Back Pain Patients With Lower Cross Syndrome
This study will be conducted toinvestigate the effect of Global Postural Re-education on low back pain patients with Lower cross syndrome
- Trial name
- NCT05664022
- Testing
- Global postural reeducation
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Coronary Artery Disease
Troponin in Acute Chest Pain to Risk Stratify and Guide EffecTive Use of Computed Tomography Coronary Angiography
Most patients presenting to hospital with symptoms of a heart attack are sent home without further tests once a heart attack has been ruled out.
- Trial name
- TARGET-CTCA (NCT03952351)
- Testing
- CT Coronary Angiography (CTCA)
- Where
- 9 sites in United Kingdom
- Volunteers
- 3,170 people
- Sponsor
- University of Edinburgh
Coronary Artery Disease, Angina Pectoris
Radiosurgery of Ganglion StELlatum In Patients With REFractory Angina Pectoris
The core hypothesis to be tested is that the radiosurgery of stellate ganglion (left one or both if left-sided without full relief of symptoms) is an effective therapy of refractory angina pectoris in patients with no other…
- Conditions
- Coronary Artery Disease, Angina Pectoris, Myocardial Ischemia
- Trial name
- RELIEF-AP (NCT05600751)
- Testing
- Radiosurgery of ganglion stellatum
- Where
- 2 sites in Czechia
- Volunteers
- 10 people
- Sponsor
- University Hospital Ostrava
Rheumatic Diseases
A Study on Health - Related Quality of Life in Patients With Rheumatic Diseases Taking Tramadol 37.5mg/Acetaminophen 325mg Tablets
The objective of this observational study is to assess improvement of quality of life in the patients who are administered Tramadol 37.5mg/Acetaminophen 325mg tablets for 10~14 weeks according to the investigator's discretion in…
- Trial name
- NCT00642837
- Testing
- Tramadol/acetaminophen
- Volunteers
- 982 people
- Sponsor
- Janssen Korea, Ltd., Korea
Opioid Use, Side Effect of Drug
Pharmacokinetics of Morphine and Oxycodone in Frail Elderly Undergoing Cardiac Surgery
Single centre observational cohort study. 20 older patients undergoing cardiac surgery who receive standard of care pain treatment.
- Conditions
- Opioid Use, Side Effect of Drug, Postoperative Pain
- Trial name
- NCT04696445
- Testing
- Morphine & Oxycodone
- Where
- Netherlands
- Volunteers
- 34 people
- Sponsor
- St. Antonius Hospital
Diabetic Neuropathic Pain
A Multicenter Study Comparing the Analgesic Effects and Safety of ABT-639 Compared to Placebo in Subjects With Diabetic Neuropathic Pain
People with diabetes can, over time develop nerve damage throughout the body with symptoms such as pain, tingling, or numbness (loss of feeling) in the hands, arms, feet and legs.
- Trial name
- NCT01345045
- Testing
- ABT-639, pregabalin
- Where
- 35 sites in United States, Czechia and 3 more
- Volunteers
- 193 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
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