Clinical trials: Painful
Phantom Limb, Leg Amputation
Leg Amputation and Continuous Sciatic Nerve Block
Analgesia following leg amputation is based on morphine administration. For elderly patients of ASA physical status 2 or 3, morphine sparing is possible when perinervous block techniques are used.
- Trial name
- CAPDAF (NCT00427947)
- Where
- France
- Volunteers
- 6 people
- Sponsor
- University Hospital, Bordeaux
Acute Pain, Chronic Pain, Widespread
Ketamine's Effect Changes the Cortical Electrophysiological Activity Related to Semantic Affective Dimension of Pain
This is a clinical trial that intend to determine the effects of S-ketamine on event-related potentials associated with semantic affective pain-processing
- Conditions
- Acute Pain, Chronic Pain, Widespread, Schizophrenia
- Trial name
- NCT03915938
- Testing
- Ketamine
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Tooth, Impacted, Trismus
Dexketoprofen Dosage According to Chronotherapy
Lower third molar extraction is one of the most common treatments in oral surgery practice. It is a treatment with inherent complications such as postoperative pain, swelling or trismus.
- Conditions
- Tooth, Impacted, Trismus, Pain, Inflammatory Response
- Trial name
- NCT05176158
- Testing
- Dexketoprofen 25 MG
- Where
- Spain
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Low Back Pain, Mechanical
Comparative Study of Static and Dynamic Back Supports for Lower Back Pain
Lower back pain is one of the most common conditions affecting humans. Lower back supports are a common device used in order to alleviate the pain.
- Trial name
- NCT01269619
- Testing
- Dynamic back support, Static back support
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Wolfson Medical Center
Healthy
Cold Pressor Test is Used in This Study to Assess the Effect of PF-06305591 on Pain Intensity Evoked by Cold in Healthy Male Subjects
This study will evaluate the pharmacological activity of PF-06305591 in healthy male volunteers by assessing the effects of two dose levels of PF-06305591 on cold pain intensity evoked by keeping non-dominant hand into a water…
- Trial name
- NCT01812265
- Testing
- PF-06305591
- Where
- Belgium
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Pfizer
Chronic Low Back Pain
Aging Back Clinics
The purpose of this study is to compare two different ways to treat chronic low back pain. The two types of treatment that the investigators will compare are called Usual Care and ABC Care. Usual Care tends to focus on the spine.
- Trial name
- NCT03564600
- Testing
- Aging Back Clinics management
- Where
- 3 sites in United States
- Volunteers
- 299 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Pain, Dental Anxiety
Effectiveness of Aromatherapy and Digital Anesthesia in Managing Dental Anxiety and Pain in Children
The goal of this clinical study is to learn whether aromatherapy and digital anesthesia are effective in reducing dental anxiety and pain during tooth extraction in children.
- Conditions
- Pain, Dental Anxiety, Tooth Extraction
- Trial name
- NCT07547371
- Testing
- Traditional Local Anesthesia (Conventional Syringe), Aromatherapy (Lavender or Orange Essential Oil), Digital Local Anesthesia (SleeperOne 5)
- Where
- Turkey (Türkiye)
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Arzu Pınar Erdem
Neck Pain
Effect of Bruegger's Exercise in Chronic Mechanical Neck Pain With Forward Head Posture
The purpose of the study is to investigate the effect of adding Bruegger's exercises on conventional exercise program in treatment of forward head posture.
- Trial name
- NCT07669844
- Testing
- Core stability exercise, Bruegger's training
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Cairo University
Liver Health, Digestive Health
A Clinical Trial to Evaluate the Effects of a Supplement on Symptoms Associated With Liver and Digestive Health
This study will evaluate the effects of Edenboost Alpha Cleanse, a dietary supplement, on symptoms associated with liver and digestive health.
- Conditions
- Liver Health, Digestive Health, Fatigue, Abdominal Bloating
- Trial name
- NCT07738744
- Testing
- Edenboost Alpha Cleanse
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Edenboost
Chronic Neck Pain
Effects of Minimally Invasive Techniques in Healthy and Chronic Cervical Pain Individuals
Brief Summary: This project consists of two sequential experimental phases designed to analyze the immediate and 24-hour effects of three invasive physiotherapy techniques -dry needling (DN), percutaneous neuromodulation (PENS)…
- Trial name
- NCT07345793
- Testing
- Dry needling, Percutaneous nerve stimulation, Percutaneous electrolysis
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidad Europea de Madrid
Infant Pain Management
White Noise and Buzzy for Reducing Pain During Infant Vaccination
This randomized controlled trial aims to evaluate the effectiveness of two non-pharmacological methods-white noise and the Buzzy device-in reducing pain experienced by infants during routine vaccination.
- Trial name
- NCT07286721
- Testing
- Standard Care (in control arm)
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Istanbul Arel University
Pain
Mechanism-based Choice of Therapy for Neuropathic Pain
Mechanism-based choice of therapy for neuropathic pain: Can treatments success in neuropathic post-operative pain be coupled to psychophysical pain modulation profile?
- Trial name
- NCT01359514
- Testing
- Pregabalin, Duloxetine
- Where
- Israel
- Volunteers
- 32 people
- Sponsor
- Rambam Health Care Campus
Pain, Postoperative, Acute Pain
EFFECT - EFFectiveness of ESPB (Erector Spinae Plane Block) in Laparoscopic Cοlectomies Trial
The aim of the trial is to study the efficacy of continuous bilateral Erector Spinae Plane Block (ESPB) in managing perioperative pain in patients who undergo elective laparoscopic colectomy.
- Conditions
- Pain, Postoperative, Acute Pain, Postoperative Complications, Pain
- Trial name
- EFFECT (NCT04879004)
- Testing
- Ropivacaine injection
- Where
- Greece
- Volunteers
- 40 people
- Sponsor
- Democritus University of Thrace
Pain, Post Operative Pain
Phase II Study of Inhaled AeroLEF for Analgesia After ACL Knee Surgery
To evaluate the safety and efficacy of self-titration to effective analgesia with inhaled AeroLEF in patients with moderate/severe acute pain in the post-surgical setting.
- Trial name
- Pain (NCT00791804)
- Testing
- AeroLEF
- Where
- 2 sites in Canada
- Volunteers
- 19 people
- Sponsor
- YM BioSciences
Fibromyalgia
Objective Measurement of Pain Regulation in Individuals Who Have Received Internet-delivered Exposure-based Cognitive Behavior Therapy
Fibromyalgia: a common problem that requires treatment Fibromyalgia (FM) is a highly prevalent pain syndrome characterized by generalized pain and fatigue, often leading to extensive somatic and psychological distress.
- Trial name
- NCT07054333
- Testing
- Internet-delivered exposure-based cognitive behavior therapy
- Where
- 2 sites in Sweden
- Volunteers
- 50 people
- Sponsor
- Karolinska Institutet
Pelvic Pain
Use of a Perineometer to Assess Pelvic Muscle Tone
The purpose of this study is to establish the range of pelvic floor pressure in groups of women, including women with and without pelvic pain, and compare the change in perineometer measurements between rest and maximum pelvic…
- Trial name
- NCT02345538
- Volunteers
- healthy volunteers welcome
- Sponsor
- Duke University
Postoperative Pain, Acute, Postoperative Complications
Minimally Invasive Esophagectomy Pain Control Trial
A pilot randomized controlled trial comparing intercostal nerve blocks, cryo-ablation plus intercostal nerve blocks, and serratus plane catheter plus intercostal nerve blocks in patients undergoing esophagectomies with minimally…
- Trial name
- NCT05906134
- Testing
- Local intercostal nerve block, Cryo-analgesia and intercostal nerve block, Serratus plane catheter blocks and intercostal nerve blocks
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Swedish Medical Center
Colon Tumor, Malignant, Rectum Tumor
Use of VIrtual REAlity to Reduce Postoperative Anxiety and Pain After Surgery for Colorectal Cancer
In patients operated for colorectal cancer, pain, anxiety and depression are important factors in postoperative rehabilitation. The use of new technologies, as virtual reality immersion, could further improve their postoperative…
- Conditions
- Colon Tumor, Malignant, Rectum Tumor, Pain, Postoperative
- Trial name
- VIREA (NCT05653934)
- Testing
- Pre-operative use of virtual reality headset, Standard surgery, Post-operative use of virtual reality headset
- Where
- France
- Volunteers
- 124 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Bruxism, Temporomandibular Joint Disorders
Aspects Associated With Obstructive Sleep Apnea, Bruxism and Orofacial Pain
This study evaluated the influence of the sleep bruxism (SB), awake bruxism (AB) and obstructive sleep apnea syndrome (OSAS) on the signs and symptoms of temporomandibular disorders (TMD).
- Conditions
- Bruxism, Temporomandibular Joint Disorders, Obstructive Sleep Apnea Syndrome
- Trial name
- NCT03766464
- Testing
- Evaluation of TMD and pain sensitivity, Evaluation of SB, Evaluation of AB
- Where
- Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Federal University of Pelotas
IUD Insertion Complication
Pain Management Associated With the Insertion of Jaydess® in Nulliparous Women
A multicenter prospective interventional comparative study that investigate pain management during Jaydess insertion in nulliparous women that will be tested by the analgesic affects of oral tramadol or 'verbal anesthesia' on the…
- Trial name
- Jaydess (NCT02706509)
- Testing
- Tramadol, Verbal anesthesia, Jaydess
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.