Clinical trials: Painful Bladder Syndrome
Interstitial Cystitis, Painful Bladder Syndrome
Amniotic Membrane Therapy for Interstitial Cystitis/Painful Bladder Syndrome
Interstitial cystitis/painful bladder syndrome (IC/PBS) is a clinical syndrome in which patients report symptoms of bladder and/or pelvic pain with pressure and/ or discomfort associated with urinary frequency and urgency.
- Conditions
- Interstitial Cystitis, Painful Bladder Syndrome, Painful Bladder Syndrome (PBS)
- Trial name
- NCT06096597
- Testing
- Clarix Flo
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- David Sheyn
Interstitial Cystitis, Irritable Bowel Syndrome
MAPP Investigation of Pelvic Floor-Brain Neurobiologic Axis in IC/IBS and IBS
Hypotheses: 1. The bidirectional signaling between the cortex, and the pelvic floor/gut is deranged in patients with IC and in IBS.
- Trial name
- NCT01280864
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Augusta University
Overactive Bladder, Painful Bladder Syndrome
Changes in Inflammatory and Contractile Protein Expression in Patients With Painful Bladder Syndrome/IC.
Interstitial cystitis (IC)/chronic pelvic pain syndrome (CPPS) is a clinical syndrome of pelvic pain and/or urinary urgency/frequency in absence of a specific cause such as bacterial infection or damage to the bladder.
- Conditions
- Overactive Bladder, Painful Bladder Syndrome, Chronic Pelvic Pain Syndrome, Cystitis, Interstitial
- Trial name
- NCT00775281
- Where
- Switzerland
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Interstitial Cystitis, Painful Bladder Syndrome
Pilot Study of Percutaneous Posterior Tibial Nerve Stimulation for the Treatment of IC/PBS
In 2014, the American Urological Association updated it management algorithm for Interstitial Cystitis/Painful Bladder Syndrome (IC/PBS). As the algorithm progresses, interventions become increasingly invasive and morbid.
- Trial name
- NCT02550561
- Testing
- Posterior Tibial Nerve Stimulation
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Pelvic Pain, Abdominal Pain
Female Chronic Pelvic Pain
The purpose of this study is to investigate the frequency and severity of chronic pelvic pain (CPP) in adult women living in Copenhagen Country and Zealand Country (total population 2,4 million), Denmark, in relation to selected…
- Conditions
- Pelvic Pain, Abdominal Pain, Painful Bladder Syndrome, Interstitial Cystitis
- Trial name
- Female CPP (NCT01255345)
- Testing
- Chronic pelvic pain
- Where
- Denmark
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital at Herlev
Gastrointestinal Diseases, Chronic Pain
Web-Based Survey of Pain, Stress and Complementary and Alternative Medicine
The investigators are inviting people with fibromyalgia, IBS, interstitial cystitis, chronic pain, and other chronic and recurring conditions to sign up and participate in a year-long Internet-based survey to study the…
- Conditions
- Gastrointestinal Diseases, Chronic Pain, Stress, Anxiety
- Trial name
- PROCAIM (NCT00740233)
- Volunteers
- 2,300 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Interstitial Cystitis/Painful Bladder Syndrome, Myofascial Pelvic Pain
Interstitial Cystitis: Elucidation of the Psychophysiologic and Autonomic Characteristics (ICEPAC) Study
Interstitial cystitis/painful bladder syndrome (IC/PBS) causes severe bladder pain and extensive disability in a large group of women int he prime of their productive lives.
- Trial name
- ICEPAC (NCT01616992)
- Testing
- Bupivacaine
- Where
- 2 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Case Western Reserve University
Overactive Bladder, Urgency-frequency Syndrome
OAB and the Microbiome
To determine differences in the urinary microbiomes, identified by polymerase change reaction (PCR) (UTIP™), of female patients with urgency and frequency syndrome with or without pelvic pain (Group A) compared to female controls…
- Trial name
- NCT04831801
- Where
- 2 sites in United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Miami
Healthy
Safety and Tolerability Study of the Taris Placebo System
The aim of this protocol is to evaluate the tolerability of the Taris placebo system for the development program and to provide key safety and tolerability data for the Taris platform.
- Trial name
- NCT01051336
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- TARIS Biomedical, Inc.
Control Condition (PBS), Household Detergent Exposure
Assessment of Skin Barrier Disruption Due to Daily Use of Cleaning Products and Hand Disinfectants
The goal of this clinical trial is to assess the effects of household detergents and hand disinfectants on human skin barrier integrity among healthy adult volunteers.
- Conditions
- Control Condition (PBS), Household Detergent Exposure, Hand Disinfectant Exposure, Surfactant Exposure
- Trial name
- SBDDCP (NCT06269315)
- Testing
- Cleaning product exposure
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Swiss Institute of Allergy and Asthma Research
Endometriosis, Bladder Pain Syndrome
Translational Research in Pelvic Pain
This study aims to better understand the pathways leading to pain in women with two types of pelvic pain condition (endometriosis-associated pain and bladder pain syndrome) and determine whether these pathways can be used to…
- Conditions
- Endometriosis, Bladder Pain Syndrome, Chronic Pain
- Trial name
- TRiPP (NCT04001244)
- Where
- 2 sites in Portugal, United Kingdom
- Volunteers
- 787 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Interstitial Cystitis, Bladder Pain Syndrome
Investigation of the Effectiveness of Acupuncture in Patients Diagnosed With Interstitial Cystitis
Interstitial cystitis/bladder pain syndrome is a non-bacterial chronic inflammatory disease of the bladder characterized by lower urinary tract symptoms such as dysuria, irritating urgency, and nocturia, as well as pelvic pain…
- Trial name
- NCT06232200
- Testing
- ACUPUNCTURE
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Medipol University
Pelvic Floor Disorders, Interstitial Cystitis
Adverse Childhood Experiences in Urogynecologic Patients
Adverse Childhood Experiences (ACEs) have been associated with negative health outcomes, yet scant information exists regarding the relationship between ACEs, Pelvic floor disorders, and Chronic Pelvic Pain.
- Conditions
- Pelvic Floor Disorders, Interstitial Cystitis, Urinary Incontinence
- Trial name
- ACE-UP (NCT03480477)
- Testing
- ACE questionnaire
- Where
- United States
- Volunteers
- 356 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Chronic Interstitial Cystitis
The Efficacy of Urine Biomarker in Patient With Interstitial Cystitis/Painful Bladder Syndrome (Pilot Study)
This study is to evaluate the efficacy of urine biomarker in patients with interstitial cystitis/painful bladder syndrome
- Trial name
- NCT02331472
- Where
- 2 sites in South Korea
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Asan Medical Center
Interstitial Cystitis
Peppermint Oil for the Treatment of Interstitial Cystitis / Bladder Pain Syndrome
The purpose of this study is to assess the use of peppermint oil as a treatment for Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS).
- Trial name
- NCT04845217
- Testing
- Peppermint oil, Coconut Oil
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Pulpotomy
Clinical Applicability of PBS® CIMMO Cement in Pulpotomies
Randomized clinical study in pulpotomies of deciduous molar teeth. A comparison of two techniques is established.
- Trial name
- NCT03200938
- Testing
- formocresol and zinc oxide., PBS CIMMO cement.
- Where
- 2 sites in Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidade do Vale do Sapucai
Uterine Fibroids, Contraception Desired
Prophylactic Salpingectomy for the Prevention of the Ovarian Cancer: Comparison Between Surgical Techniques
The aim of this RCT of study is to compare the outcomes of the standard salpingectomy (removal of the fallopian tube) with the radical removal of the tube and the mesosalpinx in terms of ovarian reserve.
- Trial name
- Rad_PBS (NCT02086370)
- Testing
- Standard PBS, Radical PBS
- Where
- Italy
- Volunteers
- 177 people, healthy volunteers welcome
- Sponsor
- University Magna Graecia
Interstitial Cystitis, Bladder Pain Syndrome
The CBD-IC Randomized Controlled Trial: Evaluation of Hemp Cannabidiol SuppositoRies for Pain and Urinary SymptOms in INterstitial Cystitis (CHRONIC)
This study seeks to exploit bladder cannabidiol receptors as a therapeutic drug target by conducting a double-masked, placebo-controlled randomized trial evaluating the effects of vaginal hemp cannabidiol (CBD) suppositories on…
- Trial name
- CHRONIC (NCT04349930)
- Testing
- Cannabidiol vaginal suppository
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of New Mexico
Interstitial Cystitis, Chronic Prostatitis
Chronic Pelvic Pain Study of Individuals With Diagnoses or Symptoms of Interstitial Cystitis and/ or Chronic Prostatitis
The Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Research Network has been established to focus on a broader approach to the study of Interstitial Cystitis (IC)/Painful Bladder Syndrome (PBS) in men and…
- Trial name
- MAPP-EP (NCT01098279)
- Where
- 8 sites in United States
- Volunteers
- 424 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Substance Abuse, Mental Health
Implementing School Wide PBS in Middle Schools: The Foundation for Effective Prevention
The research study will experimentally evaluate the impact of PBS on early adolescent development through a randomized control trial involving 36 middle schools.
- Trial name
- NCT04711681
- Testing
- Positive Behavior Supports in Middle Schools
- Where
- United States
- Volunteers
- 13,498 people, healthy volunteers welcome
- Sponsor
- University of Oregon