Clinical trials: Painful Peripheral Neuropathy
Neuropathy, AIDS
Safety and Preliminary Evidence of Efficacy of Escalating Doses of Dimiracetam in AIDS Patients With Painful Neuropathy
One hundred consenting AIDS patients suffering from treatment induced painful neuropathy will be blindly randomize to Active and Placebo groups (ratio A/P = 3/2 and will receive increasing oral doses of dimiracetam starting from…
- Trial name
- NCT01135251
- Testing
- dimiracetam, sugar pill
- Where
- South Africa
- Volunteers
- 116 people
- Sponsor
- Neurotune AG
Low Back Pain, Radiculopathy Lumbar
The Effect of Accelerometer Guided App Feedback on Change in Activity in Patients With Low Back
In a cross-over, open-label, randomized, controlled trial, the investigators aim to determine if the daily activity level in patients with LBP can be increased via feedback from an app, connected to a wearable sensor of physical…
- Conditions
- Low Back Pain, Radiculopathy Lumbar, Sciatica
- Trial name
- NCT04695912
- Testing
- The SENS motion® sensor
- Where
- Denmark
- Volunteers
- 98 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Superior Cluneal Nerve Entrapment
Treatment of Upper Cluneal Nerve Entrapment Syndrome for Reduction of Low Back Pain
Superior cluneal nerve entrapment (SCN) is a painful symptomatic condition related to compression by the thoracolumbar and gluteal bands of nerve outcrop, above the iliac crest.
- Trial name
- NCT06059612
- Testing
- injection
- Where
- Italy
- Volunteers
- 41 people
- Sponsor
- Istituto Ortopedico Rizzoli
Reflex Sympathetic Dystrophy of Upper Limb, Stroke
Peripheral Magnetic Stimulation to Treat Patient With Post-stroke Shoulder-hand Syndrome
Shoulder-hand syndrome is a common complication following stroke, constituting of excessive pain, swelling, heat, limited range of motion, and trophic change of the affected limbs.
- Trial name
- NCT05112094
- Testing
- peripheral magnetic stimulation, physical therapy
- Where
- Taiwan
- Volunteers
- 25 people
- Sponsor
- National Taiwan University Hospital
Chemotherapy-induced Peripheral Neuropathy, Pain, Neuropathic
Ozone Therapy in Chemotherapy-induced Peripheral Neuropathy: RCT (O3NPIQ)
The main objective of this clinical trial is to evaluate the effectiveness and cost-effectiveness of adding ozone therapy to the clinical management of patients with pain secondary to chemotherapy-induced peripheral neuropathy
- Conditions
- Chemotherapy-induced Peripheral Neuropathy, Pain, Neuropathic, Pain Syndrome
- Trial name
- O3NPIQ (NCT04299893)
- Testing
- Ozone, Oxygen
- Where
- 2 sites in Spain
- Volunteers
- 42 people
- Sponsor
- Bernardino Clavo, MD, PhD
Lumbar Radiculopathy
Preoperative Corticosteroid Epidural Injection and Lumbar Decompression Surgery Outcomes
This randomized control trial will compare opioid use, pain, and functional outcomes following decompression surgery for single-level lumbar radiculopathy in patients who undergo placement of corticosteroid epidural injection…
- Trial name
- NCT03543033
- Testing
- Corticosteroid injection
- Where
- United States
- Sponsor
- Lahey Clinic
Rotator Cuff Tears, Central Sensitisation
Effect of Pregabalin on Shoulder Pain in Patients With Central Sensitization After Arthroscopic Rotator Cuff Repair
This study aims to investigate the effects of Pregabalin intake on shoulder pain management in patients with central sensitization undergoing arthroscopic rotator cuff repair.
- Conditions
- Rotator Cuff Tears, Central Sensitisation, Neuropathic Pain
- Trial name
- NCT06367998
- Testing
- Pregabalin
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- The Catholic University of Korea
Coccyx Disorder, Neuropathic Pain
Vitamin D Level and Pain Type in Coccygodynia
Coccygodynia is a painful clinical picture of the sacrococcygeal region.Pain in coccygodynia may be somatic, neuropathic or mixed.
- Conditions
- Coccyx Disorder, Neuropathic Pain, Nociceptive Pain, Vitamin D Deficiency
- Trial name
- NCT05047393
- Testing
- Current blood vitamin D level and painDetect questionairre score will be detected
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people
- Sponsor
- Cumhuriyet University
Radiculopathy, Radiculopathy Lumbar
Mirror Image Spine Correction Exercises Versus Conservative Physiotherapy for Lumbar Radiculopathy
Lumbar radiculopathy is a common condition caused by irritation or compression of a lumbar nerve root, often resulting in radiating leg pain, numbness, weakness, and functional limitation.
- Conditions
- Radiculopathy, Radiculopathy Lumbar, Sciatica, Disc Disease Lumbar
- Trial name
- MIRROR-LR (NCT07558993)
- Testing
- Mirror Image Spine Correction Exercises, Conservative Physiotherapy
- Where
- United Arab Emirates
- Volunteers
- 64 people
- Sponsor
- University of Sharjah
Neuromyelitis Optica Spectrum Disorders (NMOSD), Neuropathic Pain
Crisugabalin in NMOSD Neuropathic Pain: A Randomized, Double-Blind, Placebo-Controlled Exploratory Trial
This study is a multicenter, prospective, randomized, double-blind, placebo-controlled exploratory investigation conducted in China.
- Trial name
- TERMINATOR (NCT07699770)
- Testing
- Crisugabalin
- Where
- 10 sites in China
- Volunteers
- 110 people
- Sponsor
- Tang-Du Hospital
HIV Infections, Peripheral Neuropathy
Study of Pregabalin Versus Placebo in the Treatment of Nerve Pain Associated With HIV Neuropathy
Study to determine if pregabalin is more effective than placebo in treating subjects with nerve pain associated with HIV neuropathy.
- Trial name
- NCT00232141
- Testing
- pregabalin
- Where
- 44 sites in United States, Puerto Rico
- Volunteers
- 302 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Chronic Myeloproliferative Disorders, Leukemia
Baclofen-Amitriptyline Hydrochloride-Ketamine Gel in Treating Peripheral Neuropathy Caused by Chemotherapy in Patients With Cancer
RATIONALE: Baclofen-amitriptyline-ketamine (BAK) gel may lessen peripheral neuropathy caused by chemotherapy. It is not yet known whether BAK gel is more effective than a placebo in treating peripheral neuropathy caused by…
- Conditions
- Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Lymphoproliferative Disorder
- Trial name
- NCT00516503
- Testing
- baclofen/amitriptyline/ketamine gel
- Where
- 165 sites in United States
- Volunteers
- 208 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Neuropathic Pain, Chronic Postsurgical Pain
Efficacy of an Intraoperative Periradicular Application of Platelet Rich Fibrin (PRF) on the Intensity of Residual Post-surgical Neuropathic Pain After a Surgery for Disc Herniation
The prevalence of post-surgical lumbar neuropathic radiculopathy is approximately 30%. Poor response to the treatments recommended for neuropathic pain, namely antidepressants and/or gabapentinoids, requires the development of…
- Trial name
- NeuroPRF (NCT05196503)
- Testing
- Treatment
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Strasbourg, France
Neuropathic Pains, Vasoocclusive Sickle Cell Crises Pains
Lidocaine 5% Plasters (Versatis® 5%) in Pediatric Neuropathic Pains and Vasoocclusive Sickle Cell Crisis Pains
Lidocaine 5% plaster (VERSATIS® 5%) showed its efficacy and safety in the post-herpetic zoster adult pains. This treatment is recommended in first intention in adult neuropathic pains with allodynia.
- Trial name
- NCT01314300
- Testing
- Lidocaine
- Where
- 2 sites in France
- Volunteers
- 39 people
- Sponsor
- Centre Leon Berard
Pudendal Neuralgia
Decompression of Pudendal and Inferior Cluneal Nerves Using Robot-assisted Laparoscopy for Entrapment Neuralgias : the X-DECO Study
The objective of our study is to evaluate the efficacy of the laparoscopic robot-assited approach after 1 year of follow-up, on pain experience, and anxiety, depression, post-traumatic stress syndrome and quality of life.
- Trial name
- X-DECO (NCT06578767)
- Where
- France
- Volunteers
- 200 people
- Sponsor
- UBOSGA
Peripheral Neuropathy, Painful Neuropathy
Earlier Diagnosis of Peripheral Neuropathy Using A Simple sCreening Tool (ACT)
This study is looking at people with diabetes (type 1 and type 2 diabetes) to see how well a short questionnaire, called the ACT, can identify nerve damage in the feet and legs (also known as peripheral neuropathy).
- Conditions
- Peripheral Neuropathy, Painful Neuropathy, Diabetes (DM)
- Trial name
- ACT (NCT07163000)
- Where
- Qatar
- Volunteers
- 150 people
- Sponsor
- Weill Cornell Medical College in Qatar
Intervertebral Disc Displacement, Low Back Pain
Exercise Therapy After Caudal Epidural Steroid Injection
Brief Summary Lumbar radicular pain arising from intervertebral disc herniation is commonly managed with a caudal epidural steroid injection (CESI), a minimally invasive procedure that delivers anti-inflammatory medication to the…
- Conditions
- Intervertebral Disc Displacement, Low Back Pain, Radiculopathy
- Trial name
- CAPER (NCT06956664)
- Testing
- Conventional Physiotherapy, Aerobic Exercise Programme, Core-Stabilization Exercise Programme
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Çankırı Karatekin University
Unilateral Carpal Tunnel Syndrome
Acute Human Study: StimRouter for Peripheral Nerve Stimulation of Discrete Peripheral Nerves
This study is being done to see how well a new investigational medical device, the StimRouter (STR) System, will work to treat the chronic pain in people who have failed previous treatments for Carpal Tunnel Syndrome (CTS) pain…
- Trial name
- StimRouter (NCT00665132)
- Testing
- StimRouter System
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Bioness Inc
Chronic Low Back Pain, Radiculopathy
Effect of Alexithymia on Treatment Response to Transforaminal Epidural Steroid Injections in Chronic Low Back Pain
Low back pain and lumbosakral radiculopathy represent common clinical challenges substantially diminishing health-related quality of life and work productivity.
- Conditions
- Chronic Low Back Pain, Radiculopathy, Alexithymia
- Trial name
- NCT07828132
- Testing
- Psychometric Assessment and Clinical Follow-up Battery
- Volunteers
- 60 people
- Sponsor
- Marmara University
Neuralgia, Postherpetic
PH-797804 Versus Placebo For The Treatment Of Neuropathic Pain Associated With Post-Herpetic Neuralgia
This is a proof-of-concept study to determine if PH-797804 reduces neuropathic pain associated with post-herpetic neuralgia. Suitable patients will be randomized to receive either PH-797804 or placebo for 4 weeks, during which…
- Trial name
- NCT00614705
- Testing
- PH-797804
- Where
- 25 sites in Chile, Russia and 4 more
- Volunteers
- 80 people
- Sponsor
- Pfizer