Clinical trials: Palatability
Taste Sensitivity, Umami Taste Perception
Umami Taste Intensity and Meal Intake
Sweet and salty tastes can influence food intake. Increased intensity of these tastes has been shown to decrease food intake and increase satiation compared to the less intense taste, independent of palatability.
- Conditions
- Taste Sensitivity, Umami Taste Perception, Food Intake Regulation, Hedonic Function
- Trial name
- OptUmami (NCT07421466)
- Testing
- Hedonic mapping, Ad libitum risotto test meal
- Where
- Netherlands
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Healthy
A Study To Investigate The Taste Of Crizotinib Liquid In Trained Healthy Adult Volunteers
An oral-liquid, pediatric form of crizotinib designed for use by pediatric patients is being tested for its' palatability in adults.
- Trial name
- NCT01125904
- Testing
- crizotinib
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Pfizer
Functional Constipation
The Efficacy and Palatability of Developed Polyethylene Glycol-based Formula for Children With Functional Constipation
This study aims to evaluate the efficacy and palatability of a developed polyethylene glycol-based formula compared with the standard polyethylene glycol (PEG) in the treatment of children with functional constipation for 8…
- Trial name
- NCT06357897
- Testing
- Local PEG4000, Commercial PEG4000
- Where
- Thailand
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Feeding Behavior
Effects of Varying Portion Size and Palatability on Food Intake of Preschool Children
The aim of the study is to determine the effect of varying both the portion size and the appeal (palatability and presentation) of foods served to preschool children at a meal on the outcomes of food and energy intake at the meal.
- Trial name
- NCT03643250
- Testing
- Smaller Portion Size and Standard Appeal (non-divided plate), Smaller Portion Size and Enhanced Appeal (divided plate), Larger Portion Size and Standard Appeal (non-divided plate)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Penn State University
Medication Palatability
Acceptability of Various Available Midazolam Formulations (Syrup, Rectal Suppository, Oro-dispersible Minitablet) in Clinical Practice
This observational study aims to gain knowledge on how the different midazolam formulations (oral syrup, rectal suppository, ODMT) are accepted by 2- to 10-year-old pediatric inpatients and outpatients at the University…
- Trial name
- NCT05894057
- Testing
- Data collection on acceptability of midazolam administration by 2- to 10-year-old pediatric patients at UKBB
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- University Children's Hospital Basel
Appetite, Gastrointestinal Transit
Ultra-Processed Foods, Palatability, Appetite, and Gastrointestinal Transit
The goal of this clinical trial is to learn how food processing level affects appetite and gastrointestinal transit time when meal palatability is changed. Participants will complete one screening visit and four test visits.
- Conditions
- Appetite, Gastrointestinal Transit, Food Processing, Food Palatability
- Trial name
- NCT07600281
- Testing
- Palatable Ultra-Processed Food Meal, Unpalatable Ultra-Processed Food Meal, Palatable Non-Ultra-Processed Food Meal
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Purdue University
Nicotine Use Disorder
Study to Assess PK, PD, Nicotine Extraction, Palatability, Subjective Effects of Nicotine Pouches - Daily Nicotine Users
This is an explorative, open-label, randomised, 3-way cross-over study to assess pharmacokinetics (PK), pharmacodynamics (PD), safety and tolerability, nicotine extraction, palatability and subjective effects after single use of…
- Trial name
- NCT06170138
- Testing
- Test product 1 - Test product 2 - Comparator product
- Where
- Sweden
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Amplicon AB
Pregnancy
Delivery Vehicles for Prenatal Calcium Supplementation
The SickKids-led research team is currently developing a prenatal micronutrient powder that will contain calcium, iron, and folic acid with different absorption characteristics.
- Trial name
- NCT01676636
- Testing
- Traditional Tablet, Chewable tablets, Unflavoured Powder
- Where
- 2 sites in Bangladesh, Canada
- Volunteers
- 149 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Healthy Adults
Using Bitter Taste Receptor Blockers to Improve the Palatability of Pediatric Medicines
Many people, particularly small children, must take drugs in liquid form because they cannot swallow pills or capsules. The bad taste of some liquid drugs can keep patients from taking drugs they need for their health.
- Trial name
- NCT06929455
- Testing
- Flavor additives
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Monell Chemical Senses Center
Colon Cancer
The Effect of Mentholyptus Drops on the Palatability of PEG-Electrolyte Solution
The investigators aim is to study the efficacy of mentholyptus drops in improving the palatability of PEG-electrolyte solution used in bowel cleansing for colonoscopy.
- Trial name
- NCT01541683
- Testing
- PEG solution (Fortrans®) and Mentholyptus Drops (Halls®), PEG solution (Fortrans®)
- Where
- Lebanon
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Gaucher Disease
Taste Evaluation of Different Liquid Formulations With Eliglustat
Primary Objective: The purpose of this study is to assess the palatability of eliglustat prototype liquid formulations in healthy subjects.
- Trial name
- NCT02422654
- Testing
- eliglustat
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Genzyme, a Sanofi Company
Child Development
Flavour Programming: Fruit and Vegetable Palatability
Infants have an inborn preference for sweet and umami flavours and dislike sour and bitter, but there is evidence that sensory experiences beginning early in development can modify these preferences in favour ultimately of…
- Trial name
- FLAVOUR (NCT03058523)
- Where
- United Kingdom
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Healthy Volunteers
Evaluate Taste and Relative Bioavailability of Two Microsphere Formulations of Crizotinib in Healthy Participants
The primary purpose of the study is to estimate the relative bioavailability and palatability of 2 new crizotinib formulations to the commercially available crizotinib formulated capsule at a 250 mg dose administered under fasted…
- Trial name
- NCT03978143
- Testing
- Treatment A, Treatment B, Treatment C
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Pfizer
Cystic Fibrosis, Steatorrhea
An Effectiveness, Safety, and Palatability Study of Pancrelipase Microtablets in Infants and Toddlers With Cystic Fibrosis and Fat Malabsorption
The purpose of this study is to evaluate the effectiveness and safety of PANCREASE MT (pancrelipase microtablets) to improve steatorrhea (excessive excretion of fat in feces) in infants and toddlers with cystic fibrosis who have…
- Trial name
- NCT00217204
- Testing
- Pancrelipase microtablets
- Volunteers
- 18 people
- Sponsor
- McNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc.
Preoperative Care, Antioxidants
Palatability of Antioxidant Biscuits
Patients who are due to have planned bowel surgery will be invited to take part in the study. Those that consent, will be given a 5 day supply of 'Fitabisc' (a biscuit designed to have the potential to provide nutritional…
- Trial name
- Fitabisc2 (NCT04027504)
- Testing
- Fitabisc
- Where
- United Kingdom
- Sponsor
- Hull University Teaching Hospitals NHS Trust
Healthy
Cross-over Study to Evaluate the Palatability of New Orally Disintegrating Tablets (ODTs) of Praziquantel (PZQ) and L-PZQ Versus Current PZQ Tablets in African Children Age 6-11 Years
The primary objective of the trial is to compare the "overall palatability" of the new orally disintegrating L-Praziquantel (L-PZQ ODT), the new racemate PZQ ODT (Rac-PZQ ODT) and the current available racemate PZQ tablets…
- Trial name
- NCT02315352
- Testing
- L-PZQ ODT, Rac-PZQ ODT, Cesol®
- Where
- Tanzania
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Merck KGaA, Darmstadt, Germany
Diet, Healthy
Tolerance and Palatability of 10-day Supplementation With Hemp Oil, Calamari Oil, and Broccoli Extract in Healthy Adults
Tolerance and palatability of short-term supplementation with a whole-food dietary formulation based on hemp oil, calamari oil, and broccoli was evaluated in healthy adults.
- Trial name
- NCT06081140
- Testing
- Standard Process Hemp Oil Complex
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Standard Process Inc.
PKU
Evaluation of PKU UP
PKU UP is a prospective, single-arm, open-label, 26-week acceptability study to evaluate PKU UP for the dietary management of participants with phenylketonuria (PKU).
- Trial name
- PKU UP (NCT05995717)
- Testing
- PKU UP
- Where
- 7 sites in United Kingdom
- Volunteers
- 16 people
- Sponsor
- Vitaflo International, Ltd
Deficiency of Micronutrients
Evaluation of ZestiVits in Children and Adults on a Ketogenic or Restricted Therapeutic Diet
A study to evaluate the acceptability of ZestiVits; a new vitamin, mineral and trace element supplement for children aged 11 years and over and adults on a ketogenic or restricted therapeutic diet with regard to product…
- Trial name
- ZestiVits (NCT02825758)
- Testing
- ZestiVits
- Where
- 3 sites in United Kingdom
- Volunteers
- 15 people
- Sponsor
- Vitaflo International, Ltd
Bioequivalence
Bioequivalence of a Single-dose of 12 mg IVERMECTIN as Orally Disintegrating Mini Tablets Versus a Single-dose of 12 mg Regular IVERMECTIN Tablets in Healthy Adults Under Fasting Conditions
This is a phase I, single-center, open-label, randomized, two-period, two-way crossover, single-dose bioequivalence study in which the active substance ivermectin is administered as a single dose of 12 mg as either CHILD-IVITAB…
- Trial name
- CHILD-IVITAB (NCT05477810)
- Testing
- Treatment A (investigational drug) followed by Treatment B (reference drug), Treatment B (reference drug) followed by Treatment A (investigational drug)
- Where
- Switzerland
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University Children's Hospital Basel