Clinical trials: Palate; Wound
Palatal Wound Healing, Mucogingival Defects
Active Oxygen Gel Versus Hyaluronic Acid Gel for Palatal Wound Healing After Free Gingival Graft
This randomized controlled clinical trial aims to evaluate and compare the effectiveness of different palatal dressing materials on wound healing following free gingival graft harvesting.
- Conditions
- Palatal Wound Healing, Mucogingival Defects, Free Gingival Graft Donor Site
- Trial name
- OXYHA-FGG (NCT07683351)
- Testing
- Hyaluronic Acid gel, Active oxygen gel, Gelatin sponge with flowable composite
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Suez Canal University
Wound Healing, Palate; Wound
Palatal Mucosa Wound Healing Following Antimicrobial Gel Application
The present study will be a prospective, randomized, triple-blind, split-mouth, clinical trial. The study timeline will be include seven total visits.
- Conditions
- Wound Healing, Palate; Wound, Hyaluronic Acid
- Trial name
- BIOR_01 (NCT06737653)
- Testing
- Gel containing postbiotics, lactoferrin, aloe barbadensis leaf juice powder and sodium hyaluronate
- Where
- Italy
- Volunteers
- 13 people
- Sponsor
- University of Roma La Sapienza
Palate; Wound
Laser Bandage and Surgical Stent as Palatal Donor Site Dressing After Free Gingival Graft Surgery.
The free gingival graft (FGG) procedure is a harvesting technique that creates an open wound that heals by secondary intention. Retarded wound healing, excessive bleeding, and postoperative pain have been reported after FGG…
- Trial name
- NCT05841641
- Testing
- Laser Bandage, Hemostatic agent with surgical stent
- Where
- India
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Krishnadevaraya College of Dental Sciences & Hospital
Palatal Wound
Influence of Electrical Stimulation on Palatal Wound Healing.
The aim of this present study is to evaluate the clinical and patients-centered parameters of electric stimulation on wound healing process of the donor palatal area after free gingival graft (FGG) removal.
- Trial name
- NCT03576339
- Testing
- Free Gingival Graft, Electric Stimulation
- Where
- Brazil
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Wound Healing, Pain, Postoperative
Evaluation of the Effects of Platelet Rich Fibrin on the Palatal Mucosal Healing
Subepithelial connective tissue graft (SCTG) has greater predictability for root coverage and causes minimal discomfort to patient.
- Conditions
- Wound Healing, Pain, Postoperative, Bleeding Wound
- Trial name
- NCT03734328
- Testing
- connective tissue graft, connective tissue graft&PRF
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Platelets Rich Fibrin, Palatal Donor Tissue
Adjunctive Role of PRF After Free Gingival Graft Harvesting - Case Series
Free gingival grafts are important to increase zone of attached gingiva and root coverage. This case series reveals role of platelet-rich fibrin (PRF) as adjunctive therapy in palatal wound healing.
- Trial name
- NCT02521467
- Testing
- Platelets Rich Fibrin in healing of palatal donor tissue
- Volunteers
- 10 people
- Sponsor
- Ain Shams University
Wound Healing
Dynamics of Wound Healing in Patients With Obesity
Healing after dental surgery can vary from person to person. This study is being done to understand how body weight (obesity vs.
- Trial name
- NCT07756112
- Testing
- Collagen Plug (standard of care), Platelet-Rich Fibrin Clot
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- University of Iowa
Gingival Vascularization, Oral Soft Tissue Wound Healing
Analysis of the Reliability and Validity of Laser Speckle Contrast Imaging
This study is designed to validate laser speckle contrast imaging (LSCI) as a non-invasive method for measuring superficial gingival blood perfusion.
- Conditions
- Gingival Vascularization, Oral Soft Tissue Wound Healing, Laser Speckle Contrast Imaging, Periodontal Wound Healing
- Trial name
- LSCI (NCT07527351)
- Testing
- Laser Speckle Contrast Imaging
- Where
- Spain
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Wound Healing
Comparing Two Wound Coverings for Healing and Comfort After Palatal Gum Graft Surgery in Adults
After gum-grafting surgery, the bare spot in the palate can be slow to heal and quite sore. In this study, the investigators are trying three dressing methods to see which helps most: Standard care: gelatin sponge alone, Option…
- Trial name
- NCT06950359
- Testing
- Gelatin Sponge Dressing (Cutanplast®), Cyanoacrylate Tissue Adhesive (PeriAcryl®), Polyglycolic Acid Sheet (Neoveil®)
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Ondokuz Mayıs University
Palate; Wound
Clinical Comparison of Application of Curcumin Gel in Pain Management After Free Gingival Graft Harvesting
The aim of this study is to compare the effect of using 2% curcumin gel versus gelatin sponge when applied to palatal donor site in pain management and wound healing after free gingival graft harvesting.
- Trial name
- curcumin (NCT05819632)
- Testing
- curcumin gel 2%
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Cleft Palate Children, Block
Suprazygomatic Nerve Block vs Surgical Site Infiltration in Cleft Palate Repair
The aim of this study is to evaluate the efficacy and duration of effect of bupivacaine given preoperatively as a bilateral suprazygomatic maxillary nerve block and to compare it with peri-incisional infiltration with the same…
- Trial name
- NCT03799068
- Testing
- suprazygomatic maxillary nerve block, surgical site infiltration
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Palate; Wound, Wound Heal
Comparison of Palatal Wound Healing in Diabetic and Non-diabetic Patients
This study aims to characterize and compare the closure of open wounds in the palatal mucosa of diabetic and non-diabetic patients, evaluate clinical, patient-centered and immunological parameters as well as wound microbiome…
- Conditions
- Palate; Wound, Wound Heal, Diabetes
- Trial name
- NCT06540690
- Testing
- Palatal Wound
- Where
- 2 sites in Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Gingival Recession, Palate; Wound
To Measure Pain Perception Following De-Epithelized Free Gingival Graft Harvesting
This randomized clinical comparative study will evaluate the postoperative pain following the FGG graft harvest procedure technique covered by four different methods for coverage of the palatal donor site.
- Trial name
- NCT03895476
- Testing
- palatal wound will be cover with collagen and sutures, palatal wound covered with platelet rich fibrin, palatal wound covered with a collagen sponge and cyanoacrylate
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Palatal Donor Site Wound Healing, Platelet Rich Fibrin
Characterizing the Effects of Platelet-Rich Fibrin (PRF) as a Palatal Wound Dressing on Quality of Life and Sleep Following Mucogingival Surgery. Study Was Conducted at the Air Force Post Graduate Dental School. All HIPPA Consents and Research Informed Consents Are Located at JBSA-Lackland.
The goal of this clinical trial (2-arm) is to determine if the application of platelet rich fibrin (PRF) to palatal donor sites influence patients quality of life, sleep efficiency, and healing following mucogingival surgery.
- Conditions
- Palatal Donor Site Wound Healing, Platelet Rich Fibrin, Sleep Quality, Pain
- Trial name
- NCT07637838
- Testing
- Platelet rich fibrin, Control Group: collagen matrices or oxidized cellulose membrane
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- 59th Medical Wing
Free Gingival Graft
Palatal Wound Healing Evaluation After Application of Platelet Rich Fibrin Versus 0.2% Hyaluronic Acid Dressings
Free gingival graft (FGG) was first proposed by Bjorn 1963 and Nabers 1966. FGG is indicated to correct mucogingival problems such as inadequate or lack of attached gingiva and gingival recession.
- Trial name
- NCT04390100
- Testing
- hyaluronic acid (Gengiegel 0.2% oral gel ), Platelet rich fibrin, Gel foam
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Pain, Postoperative, Quality of Life
To Evaluate Postoperative Pain and Quality of Life After Taking a Deephethelized Gingival Graft and Covering it With Different Treatments
Objective: To evaluate postoperative pain and quality of life in relation to oral health after obtaining a palatal de-epithelialized gingival graft and subsequent coverage of the surgical wound with an adhesive film of cellulose…
- Conditions
- Pain, Postoperative, Quality of Life, Palate; Wound
- Trial name
- NCT06408792
- Testing
- Deepithelized graft and protection technique
- Where
- Spain
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Palatal Lesion
Ozonated Gel and Titanium Platelet-rich Fibrin (on Palatal Wound Healing
Background: autogenous soft tissue grafts can be considered the gold standard for treatment of mucogingival problems. The most common site for harvesting the graft is the palate.
- Trial name
- NCT07320391
- Testing
- Ozonated Gel Application, T-PRF Application, Conventional treatment
- Where
- Egypt
- Volunteers
- 39 people
- Sponsor
- Alexandria University
Palatal Donor Site Wound Healing, Palatal Wound
Influence of Hyaluronic Acid in the Healing of Palatal Donor Sites During Free Gingival Graft Procedures
The goal of this study is to evaluate the use of a gel containing cross-linked hyaluronic acid (xHyA) at the palatal donor site following soft tissue harvesting procedures.
- Trial name
- HA Palate (NCT07458685)
- Testing
- Test - xHyA, Negative control
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- University of Milan
Insufficient Keratinized Gingiva
Evaluation of the Effectiveness of Different Procedures on Palatinal Wound Healing After Free Gingival Graft Surgery.
This study aimed to help determine the appropriate method to accelerate wound healing at the free gingival graft donor site and to minimize the patient's postoperative complaints.
- Trial name
- NCT06867055
- Testing
- Injectable platelet-rich fibrin (I-PRF), 0.8% hyaluronic acide (HA), control group
- Where
- Turkey (Türkiye)
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- SEVAL CEYLAN ŞEN
Wound Heal, Postoperative Pain
Assessing the Efficacy of a Hydrogen Peroxide Gel for Oral Wound Healing and Oral Hygiene
This study aims to assess the effectiveness and safety of a hydrogen carbamide/peroxide gel, called UNISEPT® ORAL GEL, in promoting oral wound healing, alleviating postoperative symptoms, and enhancing oral hygiene.
- Conditions
- Wound Heal, Postoperative Pain, Biopsy Wound, Wound; Mouth
- Trial name
- NCT06370260
- Testing
- Hydrogen Carbamide/Peroxide Gel
- Where
- Greece
- Volunteers
- 54 people
- Sponsor
- National and Kapodistrian University of Athens