Clinical trials: Palate; Wound
Cleft Palate, Trauma
Cell Therapy for Craniofacial Bone Defects
The purpose of this research is to determine if a patient's own bone marrow tissue can help regenerate bone in the area of the jaw where an implant will be placed. The name of the process is called Bone Repair Cell (BRC) Therapy.
- Trial name
- NCT01616953
- Testing
- Ixmyelocel-T, Autogenous Bone Grafting
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Surgical Wound
Photobiomodulation in Palate Wounds: Somatosensorial Evaluation
The goal of this clinical trial is to compare the effects of photobiomodulation with red laser on gingival graft donor areas of the palate in comparison to only protection with wound dressing.
- Trial name
- NCT06073678
- Testing
- Photobiomodulation, Protection with surgical dressing
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- University of Sao Paulo
Gingival Recession
Effect of Low-Level Laser on Pain and Healing of Donor Site Following Free Gingival Graft
The aim of this randomized split-mouth design clinical trial is to clinically evaluate the effectiveness of diode laser in the healing of donor site of palate in free gingival graft.
- Trial name
- NCT02896283
- Testing
- Low-level laser therapy, Turned-off laser
- Where
- Iran
- Volunteers
- 12 people
- Sponsor
- Tehran University of Medical Sciences
Wound Healing
Effects of CGF and Collagen Fleece on Palatal Donor Site Healing: A Randomized Clinical Trial
This study investigated whether applying Concentrated Growth Factor (CGF) or Collagen Fleece (CF) to the palatal donor site after autogenous soft tissue graft harvesting could improve wound healing and reduce postoperative…
- Trial name
- PAL-HEAL (NCT07367165)
- Testing
- Concentrated Growth Factor (CGF), Collagen Fleece (CF), Collagen Sponge (Control)
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Inonu University
Pain, Wound Healing
Effect of PRF Palatal Bandage on Pain Scores and Wound Healing After Free Gingival Graft
Background: Free gingival graft (FGG) is used to increase keratinized tissue dimensions. This prospective clinical trial was conducted aiming to determine whether the addition of an autologous platelet-rich fibrin (PRF) would…
- Trial name
- NCT02797899
- Testing
- Platelet Rich Fibrin
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Palatal Wound
Influence of Enamel Matrix Derivative (Emdogain®) on Palate Wound Healing.
The objective of this study is to evaluate clinical and patients-centered parameters of 3-month outcome of the enamel-derived matrix (EMD) application on wound healing process of the donor palatal area after free gingival graft…
- Trial name
- NCT03972267
- Testing
- Free gingival graft, Enamel Matrix Derivate
- Where
- Brazil
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Wound Heal, Platelets; Defect
Effects of Platelet Concentrates on Palatal Wound Healing
Platelet concentrates used in palatal wound healing have been reported to accelerate wound healing and reduce postoperative patient discomfort.
- Conditions
- Wound Heal, Platelets; Defect, Periodontal Inflammation, Gingival Recession
- Trial name
- NCT04097509
- Testing
- AFG application on palatinal wound healing, i-PRF application on palatinal wound healing, control
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Inonu University
Palate; Wound
Effect of Cyanoacrylate Tissue Adhesive Versus Collagen Sponge on Palatal Donor Site Healing
The goal of this clinical trial is to learn if the use of cyanoacrylate glue (PeriAcryl) is effective in healing of the palatal donor site in adults requiring a free gingival graft.
- Trial name
- RCT (NCT07086482)
- Testing
- Cyanoacrylate tissue adhesive, Collagen sponge
- Where
- Lebanon
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Beirut Arab University
Wound Healing, Palatal Wound
The Effectiveness of Nano Bio Fusion Gingival Gel (NBF) on Wound Healing at the Palate (Donor Site) After Soft Tissue Graft Surgery Compared to Placebo Gel.
The goal of this clinical trial is to assess the effect of Nano-biofusion gingival gel (NBF) on wound healing at the palatal donor site following soft tissue graft surgery and compare it to placebo gel.
- Conditions
- Wound Healing, Palatal Wound, Donor Site Complication, Inflammatory Cytokines
- Trial name
- NCT07330154
- Testing
- Application of NBF gel after soft tissue graft surgery
- Where
- Jordan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Gingival Recession, Generalized, Gingival Recession, Localized
Clinical and Histological Evaluation of Subepithelial Connective Tissue Graft Maturation at Different Healing Timepoints, With and Without Topical Application of a Polynucleotide- and Hyaluronic Acid-Based Gel
This study evaluates whether a 9-week healing interval is sufficient for subepithelial connective tissue graft (SCTG) maturation after palatal harvesting, and whether topical application of a polynucleotide and hyaluronic acid…
- Conditions
- Gingival Recession, Generalized, Gingival Recession, Localized, Wound Healing, Palate; Wound
- Trial name
- NCT07708051
- Testing
- polynucleotide and hyaluronic acid gel, subepithelial connective tissue graft harvesting
- Volunteers
- 15 people
- Sponsor
- University of Sao Paulo
Palatal Wound
Photobiomodulation of Palatal Donor Site After Free Gingival Graft Removal
The aim of this study is to compare the influence of two different energy densities for photobiomodulation on recovery of palatal donor area after free gingival graft technique.
- Trial name
- NCT03000426
- Testing
- Free gingival graft, GaAlAs laser
- Where
- Brazil
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Rare Diseases, Aniridia
Validation of Human Drugs Target of Repurposed Drugs and Novel Therapies
The cross-sectional observational clinical study related to rare eye diseases is a multi-center study in which the hypothesis is that neurokinin 1 receptor and/or substance P expression is increased in REDs associated with…
- Conditions
- Rare Diseases, Aniridia, Neurotrophic Keratopathy, Limbal Stem Cell Deficiency
- Trial name
- NCT06412718
- Volunteers
- 274 people, healthy volunteers welcome
- Sponsor
- IRCCS Ospedale San Raffaele
Heal Wound, VAS Will be Used to Assess Pain Postoperative
Evaluation of the Effect of Different Biomaterials on Palatal Wound Healing.
All study subjects will sign written informal consent form before enrolment. They will be divided into four groups, 10 patients each: Group I: Palatal wound will be left to heal spontaneously, Group II: Palatal wound will be…
- Trial name
- NCT07072182
- Testing
- Palatal wound will be covered with Ora-aid patch, Palatal wound will be covered with Composite stent, Palatal wound will be covered with PRF
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Fatma saad saad mahmoud elsherbini
Palatal Wound
Assessment of a Carvacrol-loaded Absorbable Gelatin Sponge Used as a Palatal Dressing Following Free Gingival Graft Harvesting.
To evaluate the effect of carvacrol loaded to absorbable gelatin sponge as a palatal bandage on the palatal donor site in post-operative pain reduction after free gingival graft harvesting
- Trial name
- NCT06806566
- Testing
- Carvacrol, Gelatin Sponge Sheet
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- British University In Egypt
Palate; Wound
Clinical Comparison of Alb-PRF vs PRF on Postoperative Morbidity Following FGG Harvesting
Clinical Comparison of Albumin Platelet Rich- Fibrin (Alb- PRF) versus Platelet-rich fibrin (PRF) on Postoperative Morbidity Following Free Gingival Graft Harvesting: A Randomized Controlled Clinical Trial(RCT) Study settings…
- Trial name
- NCT06567548
- Testing
- control group, Platelet-rich fibrin (PRF), Albumin Platelet Rich- Fibrin
- Where
- 3 sites in Egypt
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Cairo University
Diabetes Mellitus, Gingival Recession, Generalized
Palatal Wound Healing After Free Gingival Graft Harvest in Diabetic Patients: A Clinical Trial
The goal of this clinical trial is to evaluate local and systemic factors involved in palatal mucosal healing after Free Gingival Graft harvest in diabetic patients and to compare them with those in non-diabetic patients.
- Conditions
- Diabetes Mellitus, Gingival Recession, Generalized, Gingival Recession, Localized
- Trial name
- NCT07500935
- Testing
- Free gingival graft
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mauro Santamaria
Skin Condition, Cleft Lip and Palate
Online Psychosocial Support for Young People With a Visible Difference: A Randomised Control Study
A visible difference can have a profound impact in a society with a massive emphasis on appearance and "looks". A vulnerable group is adolescents with a condition affecting their appearance as a result of injuries (burns…
- Conditions
- Skin Condition, Cleft Lip and Palate, Burns, Other Conditions Leading to a Visible Difference
- Trial name
- UNGFaceIT (NCT03165331)
- Testing
- Ung Face IT
- Where
- Norway
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Open Wound of Palate Without Complication, Pain, Postoperative
The Effect of Ozone Therapy on Pain Perception After Free Gingival Graft Surgery in Patients With Mucogingival Defects
Gaseous ozone (O3-triatomic oxygen) is the third-strongest oxidizing agent worldwide. It influences the cellular and the humoral immune system, by stimulating the proliferation of immunocompetent cells and the synthesis of…
- Conditions
- Open Wound of Palate Without Complication, Pain, Postoperative, Free Gingival Grafts, Mucogingival Defects
- Trial name
- NCT05291715
- Testing
- Ozone generator device (Ozone DTA-APOZAa-enterprize CO9-Taiwan, R.0.C)
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Omaima Mossad Mahmoud AL-Sherbini
Adenoid Hypertrophy, Tonsillar Hypertrophy
Full-wrap Versus Conventional Suspension for Reducing Soft Palate Injury Rate in Transoral Surgery
This study aims to evaluate whether the use of full-wrap suspension, compared with the traditional double-strap suspension, can effectively reduce the risk of intraoperative and postoperative soft palate injury in…
- Conditions
- Adenoid Hypertrophy, Tonsillar Hypertrophy, Nasopharyngeal Diseases, Nasopharyngeal Tumors
- Trial name
- NCT07552545
- Testing
- Intraoperative soft palate suspension using the double-strap method., Intraoperative soft palate suspension using the full-wrap method.
- Where
- China
- Volunteers
- 138 people
- Sponsor
- Sun Yat-sen University
Inadequately Attached Gingiva (Disorder)
Assessment of Platelet-Rich Fibrin and Topical Ozonated Oil in the Management of Palatal Wound Healing After Free Gingival Graft Harvest
This randomized clinical trial was conducted to assess the effects of platelets-rich fibrin (PRF) and ozonated oil on the healing of palatal donor wound sites and the patient's morbidity after free gingival graft (FGG) harvesting
- Trial name
- NCT04828720
- Testing
- ozonated oil
- Where
- Egypt
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Cairo University