Clinical trials: Palliative Cancer
Hepatocellular Carcinoma
Systemic Chemotherapy Versus Transcatheter Arterial Chemoembolization(TACE) for Hepatocellular Carcinoma
The purpose of this study is to determine that systemic chemotherapy is superior to transcatheter arterial chemoembolization in prolonging progression-free survival（PFS） in patients with Advanced Hepatocellular Carcinoma.
- Trial name
- NCT02585479
- Testing
- Pirarubicin, Oxaliplatin, Lipiodol
- Sponsor
- Guangxi Medical University
Cancer, Neoplasm Malignant
EMPOWER 3: Improving Palliative Care Health Literacy and Utilization
Through this award, Michael Hoerger, PhD, MSCR, a psychologist at the Tulane Cancer Center in Louisiana, will lead a study called EMPOWER 3 designed to test an educational intervention to help patients understand palliative care…
- Trial name
- EMPOWER 3 (NCT04733469)
- Testing
- Multimedia Psychoeducational Intervention, Enhanced Usual Care
- Where
- 2 sites in United States
- Volunteers
- 172 people
- Sponsor
- Tulane University
Breast Cancer Stage I, Colorectal Cancer
Mind-Body Interventions for the Improvement of Quality of Life, Stress, and Sleep Quality Among Survivors of Breast, Prostate, Endometrial, or Colorectal Cancer
This clinical trial studies how well mind-body interventions work in improving quality of life (QOL), stress, and sleep quality among survivors of breast, prostate, endometrial, or colorectal cancer.
- Trial name
- NCT07745023
- Testing
- Media Intervention, Mind-body intervention, Meditation Therapy
- Volunteers
- 30 people
- Sponsor
- Roswell Park Cancer Institute
Brain Metastases, Adult, Cancer Brain
Hypofractionated Brain Radiationcavity
Stereotactic radiosurgery or hypofractionated radiotherapy of the resection cavity after metastasectomy in cancer patients with brain metastases
- Trial name
- NCT03561896
- Testing
- IGRT, SRS
- Where
- 6 sites in Switzerland
- Volunteers
- 56 people
- Sponsor
- Oncology Institute of Southern Switzerland
Malignant Mesothelioma
Palliative Therapy With or Without Chemotherapy in Treating Patients With Malignant Mesothelioma
RATIONALE: Palliative therapy may help patients with advanced cancer live more comfortably. It is not yet known if palliative therapy is more effective with or without chemotherapy in treating patients who have malignant…
- Trial name
- NCT00030459
- Testing
- cisplatin, mitomycin C, vinblastine sulfate
- Where
- 9 sites in United Kingdom
- Sponsor
- British Thoracic Society
Pancreatic Head Mass
Diagnostic Endoscopic Exploration for Pancreatic Head Mass
This study is being done to find out if an endoscope passed down the throat, through the stomach, and into the abdomen can quickly and accurately examine the organs and tissue of the abdomen and take biopsies if needed.
- Trial name
- NCT00816179
- Testing
- Transgastric diagnostic endoscopic peritoneoscopy
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Jeffrey Hazey
Colorectal Cancer
A Clinical Study on the Synergistic Effects of Zhen-Qi-Jie-Du Granules in Palliative Care for Advanced Colorectal Cancer
The goal of this clinical trial is to learn whether Zhen-Qi-Jie-Du Granules combined with chemotherapy works to treat unresectable stage IV microsatellite-stable colorectal cancer in adults.
- Trial name
- NCT07854405
- Testing
- Zhen-Qi-Jie-Du Granules II, Zhen-Qi-Jie-Du Granules I
- Where
- China
- Volunteers
- 1,540 people
- Sponsor
- Jiangsu Famous Medical Technology Co., Ltd.
Incurable Cancer Diseases, Other Incurable Diseases
Incurable Ill Patients Attitudes Towards Euthanasia and Assisted Suicide
Euthanasia and assisted dying are of growing interest for patients with incurable diseases. The possible methods are widely discussed by patient-societies, physicians, lawyers, theologians and philosophers.
- Trial name
- ESPIL (NCT00495482)
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Klinikum St. Georg gGmbH
Bladder Neoplasms
Bladder Cancer Patient-Reported Outcomes
The purpose of this study is to identify aspects of the bladder cancer (BlCa) survivorship experience that differ by clinical risk at diagnosis.
- Trial name
- NCT01090388
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- Baylor College of Medicine
Malignant Bowel Obstruction, Cancer Pain
Lidocaine Infusions for Pain in Patients With Malignant Bowel Obstruction
Malignant bowel obstruction is a frequent complication of advanced cancer, particularly of abdominal and pelvic origin, and most affected patients experience pain.
- Conditions
- Malignant Bowel Obstruction, Cancer Pain, Intestinal Obstruction
- Trial name
- NCT07856251
- Testing
- Lidocaine
- Volunteers
- 50 people
- Sponsor
- Fundación Santa Fe de Bogota
Cancer
Living Well With Serious Illness "Wicokuje Sica Tuha Akisniya Wiconi": Wawokiya Health Advocate Intervention
Informed by a Community Advisory Board (CAB) and community assessments performed in the first phase of work funded through R01CA240080, this study will test a wawokiya (one who helps) health advocate (WHA)-based palliative care…
- Trial name
- NCT05208606
- Testing
- Wawokiya Health Advocate
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
COPD, Cancer
Patient-centred Integrated Palliative Care Pathways in Advanced Cancer and Chronic Disease
Rationale: Palliative care integration in treatment pathways, palliative care networks and institutional collaborations in health services delivery seems a promising approach reducing fragmentation and discontinuity.
- Conditions
- COPD, Cancer, Heart Failure
- Trial name
- InSup-C (NCT02175147)
- Where
- 5 sites in Belgium, Germany and 3 more
- Volunteers
- 576 people
- Sponsor
- Radboud University Medical Center
Neoplasms
Oral Symptom Assessment Scale (OSAS): Validity and Reliability
Oral (mouth) symptoms are very common and often bothersome in patients with cancer. The best way to assess these symptoms is using a patient-rated symptom assessment scale.
- Trial name
- NCT04932317
- Where
- Ireland
- Volunteers
- 54 people
- Sponsor
- Our Lady's Hospice and Care Services
Sarcoma
Multicentre Retrospective Cohort Study of Palliative Care Pathways in Patients Who Died From Sarcoma
The goal of this observational study is to describe palliative pathways in adult patients who died from their sarcoma. The main question it aims to answer is: How patients who died from sarcoma are followed by palliative team.
- Trial name
- SARCOPALL (NCT07532668)
- Where
- France
- Volunteers
- 207 people
- Sponsor
- Centre Leon Berard
Cancer, Neoplasms
Mirtazapine in Cancer-related Poly-symptomatology
Multicenter, prospective, randomized, controlled trial based on a mixed-method methodology using parallel groups, of oral mirtazapine (intervention) compared with oral escitalopram (control), with a 56 days follow-up.
- Conditions
- Cancer, Neoplasms, Neoplasm Metastasis
- Trial name
- MIR-P (NCT04763135)
- Testing
- Mirtazapine, Escitalopram
- Where
- 11 sites in France
- Volunteers
- 1 people
- Sponsor
- Hospices Civils de Lyon
Tumor in Upper Gastrointestinal Canal or Patients With Colorectal Cancer
Observational Study of Early Contact With Palliative Care Unit for Patients Receiving First Line Palliative Chemotherapy With Cancer in Upper Gastrointestinal Canal, or Second Line Palliative Chemotherapy in Patients With Colorectal Cancer - an Open, Randomised Investigator Initiated Trial.
In this trial, patients with cancer in the upper gastrointestinal canal who are going to receive first line palliative chemotherapy and patients with colorectal cancer who are going to receive second line palliative chemotherapy…
- Trial name
- ALLAN (NCT02246725)
- Testing
- Contact with palliative care unit.
- Where
- Sweden
- Volunteers
- 108 people
- Sponsor
- Lund University Hospital
Malignant Thoracic Neoplasm
Electronic Symptom Monitoring Program for Triggered Palliative Referrals in Patients With Thoracic Cancer
This clinical trial evaluates earlier symptom management through remote electronic symptom monitoring (such as through an app on patient's phone), and accessibility of palliative care self-referral by patients with thoracic…
- Trial name
- NCT06396598
- Testing
- Educational Activity, Electronic Health Record Review, Internet-Based Intervention
- Where
- United States
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Neoplasms
Mobile Application Using the PRO-CTCAE to Improve Patients' Participation in Symptom Management During Treatment.
This study aims to evaluate the effect of a mobile application system using the Patient Reported Outcomes version of the Common Terminology Criteria for Adverse Events (PRO-CTCAE) to improve patients' participation in symptom…
- Trial name
- NCT04568278
- Testing
- ePRO-CTCAE application
- Where
- 2 sites in South Korea
- Volunteers
- 222 people
- Sponsor
- Samsung Medical Center
Delirium, Locally Advanced Malignant Neoplasm
Haloperidol and Lorazepam in Controlling Symptoms of Persistent Agitated Delirium in Patients With Advanced Cancer Undergoing Palliative Care
This phase II/IIII trial studies how well haloperidol and lorazepam work in controlling symptoms of persistent agitated delirium in patients with cancer that has spread to other places in the body undergoing palliative care.
- Conditions
- Delirium, Locally Advanced Malignant Neoplasm, Metastatic Malignant Neoplasm, Recurrent Malignant Neoplasm
- Trial name
- NCT03743649
- Testing
- Haloperidol, Lorazepam, Quality-of-Life Assessment
- Where
- 3 sites in United States, Brazil
- Volunteers
- 110 people
- Sponsor
- M.D. Anderson Cancer Center
Breast Cancer
Breast Cancer Registry Platform
The purpose of the project is to set up a national, prospective, longitudinal, multicenter cohort study with associated satellites, a tumor registry platform, to document uniform data on characteristics, molecular diagnostics…
- Trial name
- OPAL (NCT03417115)
- Where
- Germany
- Volunteers
- 6,150 people
- Sponsor
- iOMEDICO AG
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