Clinical trials: Palliative Cancer
End Stage Cancer
Artificial Intelligence-based Mortality Prediction Among Cancer Patients in the Hospice Ward
The purpose of this study is to develop a novel deep-learning-based survival prediction model employing patient activity data recorded by a wearable device.
- Trial name
- NCT04883879
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Taipei Medical University
Secondary Malignant Neoplasm of Bone
Primary Pain Palliation in Bone Metastases Treated With Magnetic Resonance-guided Focused Ultrasound
Magnetic Resonance guided Focused Ultrasound (MRgFUS) has demonstrated to be effective for pain control through thermally-induced cell death and periosteal denervation caused by cortical heating relative to acoustic energy…
- Trial name
- NCT01693770
- Testing
- MRgFUS
- Where
- Italy
- Volunteers
- 18 people
- Sponsor
- University of Roma La Sapienza
Cancer, Chronic Heart Failure
Palliative Outcome Evaluation Muenster I
For patients with an advanced disease and their families an excellent and compassionate care is essential. However, in hospitals optimal end-of-life care is not yet fully realized and patient's needs are often not met.
- Conditions
- Cancer, Chronic Heart Failure, COPD Exacerbation, Palliative Care
- Trial name
- POEM I (NCT03286127)
- Testing
- specialized palliative care
- Where
- 5 sites in Germany
- Volunteers
- 347 people
- Sponsor
- University Hospital Muenster
Cancer, Cardiac Disease
A Culturally-Based Palliative Care Tele-consult Program for Rural Southern Elders
Rural patients with life-limiting illness are at very high risk of not receiving appropriate care due to a lack of health professionals, long distances to treatment centers, and limited palliative care (PC) clinical expertise.
- Conditions
- Cancer, Cardiac Disease, Pulmonary Disease, Neuro-Degenerative Disease
- Trial name
- NCT03767517
- Testing
- Active Intervention, Usual Care
- Where
- 4 sites in United States
- Volunteers
- 209 people
- Sponsor
- University of Alabama at Birmingham
Bone Metastases, Bone Neoplasm
MR Imaging- Guided High Intensity Focused Ultrasound (HIFU) Therapy of Bone Metastases
Bone metastasis give rise to major complications that lead to significant morbidity and impairment of life quality. The most common primary for bone metastasis is prostate, lung and breast carcinoma.
- Conditions
- Bone Metastases, Bone Neoplasm, Bone Cancer, Bone Lesion
- Trial name
- NCT03106675
- Testing
- Thermal ablation of bone metastasis with MR-HIFU device Philips Sonalleve coupled with Philips Ingenia 3.0T, Varian Truebeam Radiotherapy System
- Volunteers
- 30 people
- Sponsor
- Turku University Hospital
Cervical Cancer
Palliative Radiation for Advanced Cervical Cancer
The present study is proposed to compare a rapid fractionation schedule of 1 week compared to a protracted schedule of 6-8 weeks for palliation for locally advanced cervical cancer.
- Trial name
- RAPPAL (NCT03997110)
- Testing
- Short course palliative radiation., Long course palliative treatment.
- Where
- India
- Volunteers
- 230 people
- Sponsor
- Tata Memorial Hospital
Breast Cancer
Adaptation and Pilot Testing of a Mindfulness-Based Insomnia and Symptom Management Intervention for Women With Breast Cancer Receiving Treatment in Rural Medically Underserved Areas
Women with breast cancer often experience multiple difficult symptoms, for example insomnia, fatigue, stress, and pain. This study is being done to test a mindfulness-based insomnia and symptom management intervention for women…
- Trial name
- NCT06529120
- Testing
- Mindfulness-Based Therapy for Insomnia with Cognitive-Behavioral Symptom Coping Skills
- Where
- 4 sites in United States
- Volunteers
- 15 people
- Sponsor
- Duke University
Carcinoma, Hepatocellular
Randomized Control Trial (RCT) of Early Palliative Care for HCC
The purpose of this research study is to evaluate the effect of early palliative care consultation on quality of life, use of hospital resources, end-of-life care and survival among Hepatocellular Carcinoma (HCC) patients with…
- Trial name
- NCT02556619
- Testing
- Early Palliative Care/Symptom Control
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- The University of Texas Health Science Center, Houston
Non-small Cell Lung Cancer
Study of Durvalumab Following Radiation Therapy in Patients With Stage 3 Unresectable NSCLC Ineligible for Chemotherapy
This is a Phase II open-label, single-arm, multicenter, international study to evaluate the clinical activity of durvalumab in patients with Stage III unresectable NSCLC who are deemed to be ineligible for chemotherapy per…
- Trial name
- DUART (NCT04249362)
- Testing
- Durvalumab
- Where
- 35 sites in United States, France and 4 more
- Volunteers
- 102 people
- Sponsor
- AstraZeneca
Palliative Care
Palliative Short Course Radiotherapy for Advanced Thoracic Cancer
The study wants to define the maximum tolerated dose (MTD), safety and efficacy of a short course radiation therapy in patients with symptomatic advanced thoracic cancer.
- Trial name
- NCT03465553
- Testing
- Short course radiotherapy
- Where
- Italy
- Volunteers
- 53 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Colorectal Cancer
Pedometer Intervention and Health Effects for Sedentary Colorectal Cancer Patients During Adjuvant Chemotherapy
Colorectal cancer is one of the most common cancers in Denmark, annually 4,200 men and women are diagnosed and approx. 2000 patients die of their colorectal cancer.
- Trial name
- NCT02522520
- Testing
- Pedometer intervention, Pedometer + hospital based intervention, Omron Walking Style pro. 20
- Where
- Denmark
- Volunteers
- 21 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Depression, Cancer Patients and Depression and Suicide
Improvement of Depression in Terminal Cancer Patients
This study investigates the potential of the water extract of Gastrodia elata Blume (WGE) to alleviate depressive symptoms in terminal cancer patients.
- Conditions
- Depression, Cancer Patients and Depression and Suicide, Life Quality
- Trial name
- IDTCP (NCT06785623)
- Testing
- Gastrodia elata Blume water extract
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Solid Tumor
Artificial Intelligence to Search for Abnormalities in Ambulatory Cancer Patients
During treatment, cancer patients may experience side effects related to their disease but also to the different treatments they receive.
- Trial name
- IASAAC (NCT05412420)
- Testing
- Patient Self-Reporting of Symptoms
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Institut de Cancérologie de Lorraine
Nursing Caries, Palliative Care
Trend Analysis of the Service of Pediatric Palliative Care
Palliative care has received considerable attention in Taiwan in recent years. The relevant research has been widely conducted for palliative care in adult population.
- Conditions
- Nursing Caries, Palliative Care, Pediatric Population, Pediatric Cancer
- Trial name
- NCT03925831
- Where
- Taiwan
- Volunteers
- 5,000 people
- Sponsor
- National Taiwan University Hospital
Fatigue
Improving Symptom Management for Cancer Patients and Their Caregivers Through Internet
Being diagnosed and treated for cancer is usually associated with severe side effects and symptoms. Cancer patients can have difficulty to manage the symptoms as a result of treatment which may cause i) an interruption or…
- Trial name
- NCT01867723
- Testing
- Internet communication application
- Where
- Norway
- Volunteers
- 560 people
- Sponsor
- Oslo University Hospital
Head and Neck Cancer, Radiotherapy
Short Course Radiation Therapy in Palliative Treatment of Head and Neck Cancer
Aim of the study is to assess efficacy of a short course radiation treatment in patients with symptomatic head and neck (H\&N) malignant lesions
- Conditions
- Head and Neck Cancer, Radiotherapy, Palliative Care
- Trial name
- NCT03804073
- Testing
- standard treatment, short course treatment
- Where
- Italy
- Volunteers
- 82 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Cancer
Implementing REmote SymPtom mOnitoring and maNagement (RESPONd)
The goal of this study is to understand if the implementation of a remote symptom monitoring and management program improves outcomes.
- Trial name
- RESPONd (NCT07024329)
- Testing
- Remote Symptom Monitoring and Management, Clinic Team Huddle
- Where
- 4 sites in Canada
- Volunteers
- 1,055 people
- Sponsor
- University of Calgary
Cancer
Improving Treatment-Related Symptom Management in Adolescents and Young Adults With Cancer
This study will test the acceptability and feasibility of a telehealth intervention to improve communication between patients and medical providers in adolescent and young adult (AYA) cancer patients receiving chemotherapy…
- Trial name
- NCT04594096
- Testing
- Telehealth visits, Standard of Care
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, Davis
Lung Cancer, Nonsmall Cell, Stage IIIA, Lung Cancer Non-Small Cell Stage IIIB
Psychosocial eHealth in Advanced Lung Cancer
Being diagnosed with cancer impairs many areas of a person's life. Although efficacious educational, emotional and social interventions exist in this regard, they often reach few survivors and late.
- Conditions
- Lung Cancer, Nonsmall Cell, Stage IIIA, Lung Cancer Non-Small Cell Stage IIIB, Lung Cancer Non-Small Cell Stage III, Lung Cancer Stage IV
- Trial name
- NCT05497973
- Testing
- E-health ecosystem of stepped psychosocial care, Usual psychosocial care
- Where
- Spain
- Volunteers
- 152 people
- Sponsor
- Institut Català d'Oncologia
Constipation, Neoplasms
Constipation in Pediatric Cancer Patients Receiving Vinca Alkaloids or Narcotics
This study will evaluate a questionnaire for measuring constipation in children with cancer. The questionnaire used in this study (Constipation Assessment Scale) reliably predicts the presence and severity of constipation in…
- Trial name
- NCT00032682
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
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