Clinical trials: Palliative Cancer
Cancer, Breast Cancer
Symptom Management and Transitioning to Engagement With Post-treatment Care for Adolescent and Young Adult Cancer Survivors
The purpose of this study is to determine the effectiveness of a digital health program called AYA STEPS, which is designed to help adolescent and young adult (AYA) cancer survivors manage symptoms and engage in recommended…
- Conditions
- Cancer, Breast Cancer, Colorectal Cancer, Sarcoma
- Trial name
- AYA STEPS (NCT06371768)
- Testing
- AYA Educational Information, AYA STEPS
- Where
- United States
- Volunteers
- 260 people
- Sponsor
- Duke University
Palliative Care
Apoyo Con Carino: Patient Navigation for Palliative Care for Non-Cancer Illness
Palliative care is a priority area of focus for the National Institute of Nursing Research. Despite the evidence-based benefits of palliative care, access remains limited, especially in poor urban and rural settings.
- Trial name
- NCT03181750
- Testing
- Patient Navigator Intervention Group
- Where
- 6 sites in United States
- Volunteers
- 299 people
- Sponsor
- University of Colorado, Denver
Oncology, Solid Tumors
Study of Avelumab-M3814 Combinations
The main purpose of the study was to evaluate a safe, tolerable recommended Phase II dose (RP2D) and/or the maximum tolerated dose (MTD) of M3814 when given in combination with avelumab with and without radiotherapy in…
- Trial name
- NCT03724890
- Testing
- M3814, Avelumab, Radiotherapy
- Where
- 8 sites in United States
- Volunteers
- 57 people
- Sponsor
- EMD Serono Research & Development Institute, Inc.
Advanced Cancer
Decision Aid to Support Advanced Cancer Patients
To support advanced cancer patients, for whom standard therapy is no longer available, and their oncologists in therapy decisions, the investigators aim to develop a decision-making aid (DA) in a multi-phased bicentric study.
- Trial name
- PETUPAL (NCT04606238)
- Testing
- Decision Aid
- Where
- Germany
- Volunteers
- 70 people
- Sponsor
- University Hospital Heidelberg
Advanced Cancer
Early, Integrated, Specialized Palliative Rehabilitation
The purpose of this study is to identify whether patients with newly diagnosed advanced cancer benefit from a 12-week palliative rehabilitation program integrated with standard oncology treatment.
- Trial name
- NCT02332317
- Testing
- Palliative rehabilitation
- Where
- Denmark
- Volunteers
- 301 people
- Sponsor
- Vejle Hospital
Cancer
Assessment of the Reasons for Accepting or Refusing Early Palliative Care
This is a prospective, multicentre study, considered as " non-RIPH ("Recherche n'Impliquant pas la Personne Humaine - Research that does not involve humans ".
- Trial name
- PALPHA-1 (NCT04717440)
- Where
- France
- Volunteers
- 37 people
- Sponsor
- Centre Leon Berard
Cancer
Electroacupuncture in Symptom Management After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy
The investigators are conducting this research study is to evaluate the feasibility (recruitment, compliance, safety, and acceptance) of using electroacupuncture (EA) to manage complex symptoms such as pain, nausea/vomiting…
- Trial name
- NCT06340906
- Testing
- Electroacupuncture
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- University of California, Irvine
Recurrent Ovarian Epithelial Cancer, Recurrent Ovarian Germ Cell Tumor
Palliative Care in Improving Quality of Life and Symptoms in Patients With Stage III-IV Pancreatic or Ovarian Cancer
This randomized clinical trial studies palliative care in improving quality of life and symptoms in patients with stage III-IV pancreatic or ovarian cancer.
- Conditions
- Recurrent Ovarian Epithelial Cancer, Recurrent Ovarian Germ Cell Tumor, Recurrent Pancreatic Cancer, Stage III Pancreatic Cancer
- Trial name
- NCT01927393
- Testing
- palliative care, educational intervention, quality-of-life assessment
- Where
- United States
- Sponsor
- City of Hope Medical Center
Advanced Cancer
Virtual Dignity Therapy for Palliative Care Patients With Advanced Cancer
The purpose of this study is to determine if it is feasible and acceptable to recruit for and deliver the Virtual Dignity Therapy intervention to palliative care patients with advanced cancer.
- Trial name
- NCT05113199
- Testing
- Virtual Dignity Therapy
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Mayo Clinic
Colorectal Cancer
Palliative Chemotherapy in Treating Patients With Advanced Colorectal Cancer
RATIONALE: Palliative chemotherapy may help patients with advanced colorectal cancer live longer and more comfortably. PURPOSE: Randomized phase III trial to compare the effectiveness of and quality of life following three…
- Trial name
- NCT00002893
- Testing
- fluorouracil, leucovorin calcium, raltitrexed
- Where
- United Kingdom
- Volunteers
- 900 people
- Sponsor
- Medical Research Council
Breast Cancer Survivorship
To Live Better After Breast Cancer Treatment
The most common cancer among women in Sweden is breast cancer. Advances in treatment have improved survival, but these advances have come at a steep price since most treatments impose substantial morbidity and burden on patients…
- Trial name
- NCT06471452
- Testing
- Interaktor
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Karolinska Institutet
Recurrent Adult Hodgkin Lymphoma
A Phase 1/2 Study of Lenalidomide in Combination With Bendamustine in Relapsed and Primary Refractory Hodgkin Lymphoma
Management of patients with recurring Hodgkin lymphoma (HL) after stem cell transplantation failure represents a typical unmet medical need prompting active development and validation of new agents and treatment strategies.
- Trial name
- LEBEN (NCT01412307)
- Testing
- Lenalidomide, Bendamustine, Bio-specimen Retention
- Where
- Italy
- Volunteers
- 36 people
- Sponsor
- Istituto Nazionale Tumori IRCCS - Fondazione G. Pascale
Cancer, Neoplasms
Mobile Health Intervention to Improve Adherence to Oral Anticancer Therapy
New oral anticancer treatments have improved survival across cancer types but introduced challenges in medication adherence and symptom management.
- Trial name
- SMART pilot (NCT07073807)
- Testing
- SMART Intervention using TAPPT® for Adherence, Symptom, Financial, and Social Needs Monitoring
- Where
- 5 sites in United States
- Volunteers
- 35 people
- Sponsor
- University of California, Irvine
Bone Metastases, Multiple Myeloma
ExAblate (MRgFUS) Treatment of Metastatic Bone Tumors for the Palliation of Pain
A Pivotal Study to Evaluate the Effectiveness and Safety of ExAblate Treatment of Metastatic Bone and Multiple Myeloma Tumors for the Palliation of Pain in Patients Who are not Candidates for Radiation Therapy
- Trial name
- NCT00656305
- Testing
- ExAblate MRfFUS
- Where
- 14 sites in United States, Canada and 3 more
- Volunteers
- 147 people
- Sponsor
- InSightec
Advanced Cancer
A Structured Early Palliative Care Intervention for Patients With Advanced Cancer - a Randomized Controlled Trial With a Nested Qualitative Study (SENS Trial)
It is assumed that an early palliative care structured by SENS (a systematic, problem-based assessment system) in addition to standard oncology care compared with standard oncology care alone relieves distress in patients with…
- Trial name
- SENS (NCT01983956)
- Testing
- SENS model
- Where
- 3 sites in Switzerland
- Volunteers
- 150 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Colorectal Cancer, Steatohepatitis
A Randomized, Placebo-controlled, Double-blind Phase II Study Evaluating if Glucophage Can Avoid Liver Injury Due to Chemotherapy Associated Steatosis
This multicenter randomized, placebo-controlled phase II study will enroll 132 first-line palliative treated subjects with metastatic KRAS wild type CRC.
- Trial name
- G-LUCAS (NCT01523639)
- Where
- 7 sites in Austria
- Volunteers
- 8 people
- Sponsor
- Austrian Breast & Colorectal Cancer Study Group
Malignant Solid Neoplasm, Malignant Head and Neck Neoplasm
Symptom Management to Improve Completion of Patient-reported Outcome Measures
In this clinical trial, patient reported outcome (PRO) assessment completion is compared between patients (undergoing systemic therapy for head and neck or lung cancer) who receive additional symptoms monitoring and…
- Conditions
- Malignant Solid Neoplasm, Malignant Head and Neck Neoplasm, Malignant Lung Neoplasm
- Trial name
- NCT07723495
- Testing
- Monitoring of PROMIS symptoms and physical function, Monitoring of additional symptoms and symptom self-management
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Henry Ford Health System
Oligoprogression, Oligometastatic Disease
Stereotactic Radiotherapy Versus Palliative Conventional Radiotherapy for Oligoprogressive Metastatic Cancers
STOP-2 is a phase III multi-institutional double-blind randomized trial. 194 participants will be enrolled in this trial. Participants will be randomized in a 1:1 ratio between the Control Arm vs. the Experimental Arm.
- Conditions
- Oligoprogression, Oligometastatic Disease, OligoProgressive Metastatic Disease
- Trial name
- NCT06918951
- Testing
- Stereotactic ablative radiotherapy (SABR), Palliative radiotherapy
- Where
- Canada
- Volunteers
- 194 people
- Sponsor
- British Columbia Cancer Agency
Colorectal Cancer, Constipation, Impaction, and Bowel Obstruction
Octreotide as Palliative Therapy for Cancer-Related Bowel Obstruction That Cannot Be Removed by Surgery
RATIONALE: Palliative therapy with octreotide may help patients who have bowel obstruction that cannot be removed by surgery to live longer and more comfortably.
- Conditions
- Colorectal Cancer, Constipation, Impaction, and Bowel Obstruction, Extrahepatic Bile Duct Cancer, Gastric Cancer
- Trial name
- NCT00004895
- Testing
- octreotide acetate
- Where
- United States
- Sponsor
- Northwestern University
Cancer, Pain
Symptom Clusters in Cancer Patients and Their Caregivers- a Longitudinal Study
The complexity of cancer patients' symptoms and health problems constitutes considerable distress and burden for patients and their family caregivers.
- Conditions
- Cancer, Pain, Fatigue, Depression
- Trial name
- NCT00769301
- Where
- 3 sites in Norway
- Volunteers
- 570 people
- Sponsor
- Oslo University Hospital
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