Clinical trials: Palliative Cancer
Palliative Care
With Love: Using Promotoras for a Hispanic Community Palliative Care Promotora Palliative Care
Despite being strongly recommended, the integration of palliative care in oncology has not been widely adopted. Very few people have access to comprehensive palliative care. Access is even lower in rural and Hispanic communities.
- Trial name
- NCT03736031
- Testing
- Intervention (Promotora)
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Texas Tech University Health Sciences Center, El Paso
Recurrent Ovarian Epithelial Cancer, Recurrent Ovarian Germ Cell Tumor
Palliative Care in Improving Quality of Life and Symptoms in Patients With Stage III-IV Pancreatic or Ovarian Cancer
This randomized clinical trial studies palliative care in improving quality of life and symptoms in patients with stage III-IV pancreatic or ovarian cancer.
- Conditions
- Recurrent Ovarian Epithelial Cancer, Recurrent Ovarian Germ Cell Tumor, Recurrent Pancreatic Cancer, Stage III Pancreatic Cancer
- Trial name
- NCT01927393
- Testing
- palliative care, educational intervention, quality-of-life assessment
- Where
- United States
- Sponsor
- City of Hope Medical Center
Cancer, Pediatric Cancer
Integrative Health Interventions in Symptom Management of Pediatric Patients
As healthcare demands high-quality cost-effective care and patients seek self-management strategies, integrative medicine has become more of an interest to patients, physicians, and administrators.
- Trial name
- NCT05594693
- Testing
- Questionnaire, Physical Exam
- Where
- 3 sites in United States
- Volunteers
- 100 people
- Sponsor
- University of Colorado, Denver
Advanced Cancer, Lung Cancer
Implementing Acupuncture and Chinese Herbal Medicine Into Palliative Care
In this clinical trial we want to investigate the clinical benefit of a complementary therapy using therapeutical modalities of the traditional chinese medicine in patients suffering from advanced cancer.
- Conditions
- Advanced Cancer, Lung Cancer, Breast Cancer, Colo-rectal Cancer
- Trial name
- NCT04584775
- Testing
- Treatment modalities of Traditional Chinese Medicine (Acupuncture, Chinese herbal medicine, Tunia, Chinese dietetics), Standard care
- Where
- Austria
- Sponsor
- Medical University of Graz
Hepatocellular Carcinoma
Combined Chemoembolization and Systemic Hyperthermia for Unresectable Hepatocellular Carcinoma
The objective is to evaluate the safety and therapeutic effect of combined hyperthermia and TACE for unresectable HCC
- Trial name
- NCT01817205
- Testing
- TACE with Hyperthermia Treatment
- Where
- 2 sites in Hong Kong
- Volunteers
- 8 people
- Sponsor
- Chinese University of Hong Kong
Gastric Adenocarcinoma
Surgical Resection Plus Chemotherapy Versus Chemotherapy Alone in Oligometastatic Stage IV Gastric Cancer
Surgical resection of the primary tumour and treatment of the metastatic site in oligometastatic stage IV metastatic gastric adenocarcinoma enhances survival and improves quality of life with acceptable postoperative morbidity…
- Trial name
- SURGIGAST (NCT03042169)
- Testing
- Preoperative Chemotherapy, Surgery, Postoperative chemotherapy
- Where
- France
- Volunteers
- 6 people
- Sponsor
- University Hospital, Lille
Cancer
Cancer & Chemotherapy Symptom Management Using an Automated Telephone Reporting System
The purpose of this study was to test the efficacy of a computer-based automated symptom monitoring telephone system used by patients who received chemotherapy for their cancer to communicate unrelieved symptoms they experienced…
- Trial name
- NCT01979146
- Testing
- Provider Unrelieved Symptom Alert
- Where
- 3 sites in United States
- Volunteers
- 250 people
- Sponsor
- University of Utah
Cancer
Randomized Controlled Trial of Early Palliative Care for Patients With Advanced Cancer
Patients with advanced cancer often have numerous physical and psychological symptoms, which can negatively affect their quality of life.
- Trial name
- NCT01248624
- Testing
- Early Palliative Care Referral
- Where
- Canada
- Volunteers
- 461 people
- Sponsor
- University Health Network, Toronto
Secondary Bone Cancer, Bone Metastases
MRgFUS Versus EBRT in Patients With Metastatic Non-spinal Bone Disease
The objective of this trial is to collect and compare safety and effectiveness data of Magnetic Resonance guided Focused Ultrasound (MRgFUS) using the ExAblate 2100 device and radiotherapy in the treatment of metastatic bone…
- Trial name
- NCT03404362
- Testing
- Bone Metastases Pain treatment
- Where
- 2 sites in Italy
- Volunteers
- 198 people
- Sponsor
- University of Roma La Sapienza
Management of Oral Care and Cancer in Palliative Situation
Oral Care and Cancer: Assessing the Contribution of Training Healthcare Teams to Support the Oral Status of Patients Hospitalized in Palliative Situation
The purpose of this study is to measure the impact of training on the practical assessment and management of the oral status of patients hospitalized in palliative situation.
- Trial name
- NCT02208908
- Testing
- Evaluation of the oral conditionand proper care
- Where
- 5 sites in France
- Volunteers
- 280 people
- Sponsor
- Centre Francois Baclesse
Acute Myeloid Leukemia, Myelodysplastic Syndromes
A Collaborative Palliative and Leukemia Care Model for Patients With AML and MDS Receiving Non-Intensive Therapy
This research study is evaluating the impact a collaborative palliative care and oncology team will have on end-of-life outcomes, quality of end-of-life care, and the quality of life, symptoms, and mood of patients with acute…
- Trial name
- NCT03310918
- Testing
- Palliative Care, Standard Leukemia care
- Where
- 2 sites in United States
- Volunteers
- 320 people
- Sponsor
- Massachusetts General Hospital
Cancer, Fatigue
The Effect of Progressive Muscle Relaxation and Deep Breathing Exercises Applied to Palliative Care Cancer Patients on Dyspnea, Fatigue, and Self-Care Behaviors
The purpose of this study is to evaluate the effects of Progressive Muscle Relaxation (PMR) exercises and deep breathing exercises on dyspnea, fatigue, and self-care behaviors among cancer patients receiving palliative care.
- Conditions
- Cancer, Fatigue, Palliative Care, Progressive Muscle Relaxation
- Trial name
- NCT07619209
- Testing
- Progressive Muscle Relaxation, Deep Breathing Exercises
- Where
- 4 sites in Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Ankara University
Metastatic Breast Cancer
Study of Palliative Radiation Combined with Pembrolizumab in Unresectable Metastatic Stage IV Breast Cancer
This is a phase 2, open-label, single-arm trial designed to evaluate the efficacy and safety of stereotactic body radiation therapy (SBRT) in combination with pembrolizumab following disease progression after two prior lines of…
- Trial name
- NCT04990921
- Testing
- Palliative Radiation and Pembrolizumab
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Louisville
Terminal Illness, Terminal Cancer
DigiPall; a Trial of Digital Patient Reported Outcome and Biomarker Monitoring in Palliative Care
The aim of this study is to test if a system consisting of a wearable device measuring heartbeats and steps, together with daily communication with a chatbot on the smartphone asking the patients about their symptoms and giving…
- Trial name
- NCT06615349
- Testing
- DigiPall
- Where
- Switzerland
- Volunteers
- 382 people
- Sponsor
- David Blum
Pancreatic Ductal Adenocarcinoma
Pilot Study Evaluating Broccoli Sprouts in Advanced Pancreatic Cancer [POUDER Trial]
The goal of the POUDER trial is to determine the feasibility of a randomized controlled trial regarding the application of freeze-dried broccoli sprouts rich in sulforaphane and quercetin in patients with advanced pancreatic…
- Trial name
- POUDER (NCT01879878)
- Testing
- Verum, broccoli sprout grain
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Heidelberg University
Recurrent Adult Hodgkin Lymphoma
A Phase 1/2 Study of Lenalidomide in Combination With Bendamustine in Relapsed and Primary Refractory Hodgkin Lymphoma
Management of patients with recurring Hodgkin lymphoma (HL) after stem cell transplantation failure represents a typical unmet medical need prompting active development and validation of new agents and treatment strategies.
- Trial name
- LEBEN (NCT01412307)
- Testing
- Lenalidomide, Bendamustine, Bio-specimen Retention
- Where
- Italy
- Volunteers
- 36 people
- Sponsor
- Istituto Nazionale Tumori IRCCS - Fondazione G. Pascale
Pancreatic Cancer, Non-Small-Cell Lung Cancer
Dignity Therapy/Life Plan in Patients With Pancreatic or Advanced Lung Cancer
This study will evaluate feasibility and acceptability of providing the Dignity Therapy/Life Plan intervention to pancreatic or advanced lung cancer patients presenting for treatment in the outpatient medical oncology setting.
- Trial name
- NCT02132325
- Testing
- Dignity Therapy
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Mayo Clinic
Gynecologic Cancer, Gastrointestinal Cancer
BOLSTER: Building Out Lifelines for Safety, Trust, Empowerment and Renewal
This research study is evaluating a new intervention, BOLSTER, which was designed to provide more support for patients with gynecologic and gastrointestinal cancers and their caregivers after a hospitalization.
- Trial name
- NCT03367247
- Testing
- BOLSTER, Enhanced Discharge Planning (EDP)
- Where
- United States
- Volunteers
- 121 people
- Sponsor
- Dana-Farber Cancer Institute
Advanced Heart Failure, Advanced Non-Colorectal Gastointestinal Cancer
Tier - Palliative Care For Patients With Advanced Heart Failure or Cancer
TIER-PC is an adaptive model of delivering palliative care that provides the right level of care to the right patients at the right time.
- Conditions
- Advanced Heart Failure, Advanced Non-Colorectal Gastointestinal Cancer, Advanced Lung Cancer
- Trial name
- TIER-PC (NCT06228209)
- Testing
- Tier-Palliative Care
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Castrate-Resistant Prostate Cancer, Hormone Refractory Prostate Cancer
A Study Evaluating the Pain Palliation Benefit of Adding Custirsen to Docetaxel Retreatment or Cabazitaxel as Second Line Therapy in Men With Metastatic Castrate Resistant Prostate Cancer (mCRPC)
The purpose of this study is to determine if the addition of study drug (custirsen) can provide durable pain palliation for castrate resistant prostate cancer patients receiving docetaxel retreatment or cabazitaxel as a second…
- Trial name
- NCT01083615
- Testing
- custirsen sodium, isotonic, 0.9% sodium chloride, docetaxel
- Where
- 33 sites in United States, Canada and 3 more
- Volunteers
- 14 people
- Sponsor
- Achieve Life Sciences