Clinical trials: Palliative Cancer
Biliary Tract Cancer
X-MAS Biliary Study With Covered Biliary Stent
The purpose of this study is to provide safety and efficacy data for the X-Suit NIR® Covered Biliary Metallic Stent for subjects with malignant stricture(s) in the biliary tree.
- Trial name
- NCT01899976
- Testing
- X-Suit NIR Covered Biliary Stent
- Where
- 9 sites in Belgium, Israel and 1 more
- Volunteers
- 68 people
- Sponsor
- Medinol Ltd.
Oxygen Dependent COPD, Advanced Malignancy
Changing the Paradigm of In-Hospital Cardiopulmonary Resuscitation
Outcomes after in-hospital cardiopulmonary resuscitation (CPR) are very poor, particularly in patients with oxygen dependent chronic obstructive pulmonary disease (COPD) or metastatic cancer.
- Trial name
- NCT01558817
- Testing
- Informed Assent, Informational Brochure
- Where
- 3 sites in United States
- Volunteers
- 29 people
- Sponsor
- University of Vermont
Advanced Cancer, Terminal Malignant Tumors
Nurses' Competence and Role in Survival Prediction and Prognostic Communication
[Background] Nurses' roles in survival prediction and prognostic communication have historically been limited due to role delineation, lack of formal training, and cultural norms.
- Conditions
- Advanced Cancer, Terminal Malignant Tumors, Hospices
- Trial name
- NCT06962553
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Acute Myeloid Leukemia, Myelodysplastic Syndrome
Early Palliative Care for Patients With Haematological Malignancies
Patients suffering from haematological disease present symptoms of discomfort and currently benefit from palliative care skills only for the management of their end-of-life.
- Conditions
- Acute Myeloid Leukemia, Myelodysplastic Syndrome, Diffuse Large B Cell Lymphoma, Palliative Care
- Trial name
- CALVI (NCT03800095)
- Testing
- Early palliative care integration
- Where
- 6 sites in France
- Volunteers
- 140 people
- Sponsor
- University Hospital, Clermont-Ferrand
Non Small Cell Lung Cancer
TEIPP Immunotherapy in Patients With NSCLC
In this multicenter, open label non-randomized phase I/II dose escalation study with extension cohort HLA-A*0201-positive patients with non small cell lung cancer (NSCLC) can be included.
- Trial name
- TEIPP (NCT05898763)
- Testing
- TEIPP24 (LRPAP7-30V-SLP vaccine in Montanide ISA-51)
- Where
- 2 sites in Netherlands
- Volunteers
- 26 people
- Sponsor
- Erasmus Medical Center
to Investigate the Level of Fatigue Among Terminal Cancer Patients Receiving Home-based Hospice Care
Cancer-related Fatigue Among Patients Receiving Home-based Palliative Care
Cancer-related fatigue, which significantly impacts the quality of life, is prevalent among patients with terminal cancer. The experiences of fatigue, its associated needs, and the strategies for managing it are closely linked to…
- Trial name
- NCT06498193
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- National Taipei University of Nursing and Health Sciences
Advanced Cancer
The PediQUEST Response Intervention Study
PediQUEST Response proposes a new system of care that expects to improve quality of life in children, adolescents, and young adults with advanced cancer and their parents.
- Trial name
- NCT03408314
- Testing
- PediQUEST Response, Usual Cancer Care
- Where
- 6 sites in United States
- Volunteers
- 194 people
- Sponsor
- Joanne Wolfe, MD, MPH
Oncological Patients, Virtual Reality
Look of Life 2.0. Virtual Reality for Cancer Patients in Home Palliative Care
Oncological disease, in addition to undermining the physical health and autonomy of the patient, is often accompanied by significant anxious and depressive symptoms that can compromise the quality of life of both patient and…
- Trial name
- LOL2020_ANT (NCT04966468)
- Testing
- Virtual Reality, Control
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Fondazione ANT Franco Pannuti ETS
Palliative Care, Cancer
Logotherapy Counseling Programme for Palliative Care Patients With Chronic Sorrow
The purpose of this study is to evaluate the effectiveness of logotherapy counseling program on chronic sorrow, meaning of life and dignity of palliative care patients.
- Trial name
- NCT05129059
- Testing
- Logotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people
- Sponsor
- Baskent University
Non-Small Cell Lung Cancer, Non-small-cell Lung Carcinoma
Combination of gp96-Ig Vaccine, Theophylline and Oxygen for the Treatment of Patients With Advanced, Relapsed or Metastatic Non-Small Cell Lung Cancer
NSCLC tumors are appropriate targets for active immunotherapy, because they are non-immunogenic, which indicates that NSCLC does not stimulate a spontaneous immune response.
- Conditions
- Non-Small Cell Lung Cancer, Non-small-cell Lung Carcinoma, Lung Cancer, NSCLC
- Trial name
- NCT01799161
- Testing
- gp96-Ig Vaccine, Theophylline, Oxygen
- Sponsor
- Eckhard Podack
Head and Neck Squamous Cell Carcinoma
3-5 FrAction Stereotactic Body Radiation Therapy for Palliation of Head and Neck Squamous Cell Carcinoma: the FAST Phase II Randomized Trial
To learn if it is effective to use advanced radiation treatment techniques (stereotactic radiation or "SBRT") to safely deliver a strong dose of radiation to your tumor in a shorter period of time than would typically be feasible…
- Trial name
- NCT05674396
- Testing
- Stereotactic body radiotherapy, Traditional Palliation
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- M.D. Anderson Cancer Center
Metastatic Esophageal Squamous Carcinoma, Gastric Cancer
Early Palliative Care in Metastatic Esophageal Squamous Carcinoma (ESCC) and Gastric Cancer
The majority of patients with newly diagnosed metastatic ESCC and gastric cancer patients experience a number of physical and psychosocial symptoms related to their cancer.
- Trial name
- NCT02375997
- Testing
- Palliative care
- Where
- China
- Volunteers
- 592 people
- Sponsor
- Peking University
Advanced Cancer, Metastatic Cancer
Emergency Department-Based Palliative Care for Advanced Cancer Patients
The purpose of this study is to: 1) identify the palliative care needs of Emergency Department patients with advanced cancer, and determine if these needs can be rapidly assessed in the ED; 2) determine whether early palliative…
- Trial name
- NCT01358110
- Testing
- Early palliative care consultation, Care as usual
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Oncology, Solid Tumors
Study of Avelumab-M3814 Combinations
The main purpose of the study was to evaluate a safe, tolerable recommended Phase II dose (RP2D) and/or the maximum tolerated dose (MTD) of M3814 when given in combination with avelumab with and without radiotherapy in…
- Trial name
- NCT03724890
- Testing
- M3814, Avelumab, Radiotherapy
- Where
- 8 sites in United States
- Volunteers
- 57 people
- Sponsor
- EMD Serono Research & Development Institute, Inc.
Pain, Pain Management
mHealth Intervention for Pain Self Management
This is a feasibility pilot test of a single-arm intervention to evaluate the beta version of an mHealth app-based behavioral intervention prior to scaling for a randomized controlled trial (RCT).
- Conditions
- Pain, Pain Management, Symptom Monitoring, Symptom Management
- Trial name
- PsyMINT (NCT07332377)
- Testing
- Mobile Health (mHealth) Intervention
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Virginia Commonwealth University
Palliative Care, Communication
Timely End-of-Life Communication to Parents of Children With Brain Tumors
A national priority for health care providers is to initiate early communication about palliative and end-of-life care (PC/EOL) for children with a poor prognosis.
- Trial name
- NCT01170000
- Where
- 4 sites in United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- The Foundation for Barnes-Jewish Hospital
Depression, Palliative Care
Methylphenidate for Depressed Cancer Patients Receiving Palliative Care
The purpose of this study is to determine whether methylphenidate is an effective treatment for depression and to document the safety and tolerability of methylphenidate in combination with an Selective Serotonin Reuptake…
- Conditions
- Depression, Palliative Care, Cancer, Mental Disorder
- Trial name
- NCT00129467
- Testing
- Methylphenidate, Selective Serotonin Uptake Inhibitor (SSRI)
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- US Department of Veterans Affairs
Prostate Cancer
A Selective Androgen Receptor Modulator for Symptom Management in Prostate Cancer
This research study is studying the use of a targeted therapy called LY SARM, which is an investigational drug from a new class of molecules called Selective Androgen Receptor Modulators (SARMs) as a possible improvement in…
- Trial name
- NCT02499497
- Testing
- LY2452473
- Where
- 4 sites in United States
- Volunteers
- 114 people
- Sponsor
- Dana-Farber Cancer Institute
Dysphagia, Esophageal Cancer
Focal Cryoballoon Ablation for Malignant Dysphagia
Rationale: Dysphagia is commonly encountered in patients with esophageal carcinoma who are no candidates for treatment with curative intent. It often has a considerable impact on quality of life and can cause malnourishment.
- Conditions
- Dysphagia, Esophageal Cancer, Cryotherapy
- Trial name
- DYS-CBAS (NCT06618742)
- Testing
- Cryotherapy
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- Laura Boer
Chemotherapeutic Agent Toxicity, Fatigue
First-Line Chemotherapy With or Without Neuromuscular Electrical Stimulation in Treating Patients With Non-Small Cell Lung Cancer
RATIONALE: Drugs used in chemotherapy, such as carboplatin and vinorelbine, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Conditions
- Chemotherapeutic Agent Toxicity, Fatigue, Lung Cancer, Musculoskeletal Complications
- Trial name
- NCT01097317
- Testing
- carboplatin, vinorelbine tartrate, neuromuscular electrical stimulation
- Where
- United Kingdom
- Volunteers
- 52 people
- Sponsor
- Wales Cancer Trials Unit