Clinical trials: Palliative Cancer
Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm
Psilocybin With Psychotherapy for Improving Chronic Pain in Cancer Patients Requiring Opioids
This phase II trial studies whether psilocybin with psychotherapy is safe and if it works for improving chronic pain in cancer patients who require opioids to manage their pain.
- Trial name
- NCT06827054
- Testing
- Biospecimen Collection, Functional Magnetic Resonance Imaging, Interview
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Roswell Park Cancer Institute
Gynecologic Cancer, Breast Cancer
Electronic Patient Reported Symptom Assessment
The purpose of this study is to assess whether using computerized screening questions can improve how well we manage symptoms related to cancer and cancer treatments.
- Conditions
- Gynecologic Cancer, Breast Cancer, Thoracic Cancer, Gastrointestinal Cancer
- Trial name
- NCT01833637
- Testing
- APN Intervention
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Northwestern University
Hepatocellular Carcinoma
Prevention of Hand-foot Skin Reaction
Sorafenib-induced hand-foot skin reaction (HFSR) is a dose-dependent side effect in patients with advance hepatocellular carcinoma (HCC).
- Trial name
- NCT04568330
- Testing
- best support care, moisture cream, 10% urea-based cream
- Volunteers
- 129 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Advanced Cancers
Perception of Palliative Care Encounter
Objectives: Primary Objective The primary objective is to determine patients' perceptions of the timeliness of their referral to an outpatient palliative care clinic. The secondary objectives are to determine: 1.
- Trial name
- NCT02558257
- Testing
- Survey
- Where
- United States
- Volunteers
- 209 people
- Sponsor
- M.D. Anderson Cancer Center
Cancer
Digital Intervention for Symptom Management in Cancer and Opioid Sparing Using Virtual Reality (DISCOVR) Study
Patients living with cancer commonly have chronic pain due to the disease or to cancer treatments. Virtual reality, a new technology that immerses the user in pleasant, diverting, and exciting virtual environments, may lower…
- Trial name
- DISCOVR (NCT07228377)
- Testing
- virtual reality pain therapy
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Medstar Health Research Institute
Cancer, Suffering
The Immediate Effect of Mindfulness-Based Supportive Therapy on Palliating Suffering in Palliative Care Cancer Patients
The was a parallel group, single-blinded, randomized controlled trial comparing the effectiveness of 30-minute mindfulness-based supportive therapy versus supportive listening in reducing suffering among patients with cancer.
- Trial name
- NCT05010239
- Testing
- 30-minute Mindfulness-Based Supportive Therapy, 30-minute supportive listening
- Where
- Malaysia
- Volunteers
- 68 people
- Sponsor
- University Malaysia Sarawak
Cancer Induced Bone Pain, Secondary Malignant Neoplasm of Bone
Thermal Testing in Bone Pain (TiBoP)
If cancer spreads to bones it can be very painful, especially when trying to move around. One of the best treatments is radiotherapy, which has to be given in a cancer centre.
- Conditions
- Cancer Induced Bone Pain, Secondary Malignant Neoplasm of Bone, Toxicity Due to Radiotherapy, Pain
- Trial name
- TiBoP (NCT02887833)
- Testing
- Clinical biomarker (thermal sensory testing)
- Where
- United Kingdom
- Volunteers
- 27 people
- Sponsor
- University of Edinburgh
Metastatic Melanoma
Radiotherapy & Combi in Metastatic Melanoma
The purpose of this study is to investigate the side effects and safety, and effectiveness of combining dabrafenib and trametinib with radiotherapy.
- Trial name
- CombiRT (NCT02392871)
- Testing
- Palliative radiotherapy, Dabrafenib and trametinib (combination)
- Where
- 3 sites in Australia
- Volunteers
- 10 people
- Sponsor
- Melanoma and Skin Cancer Trials Limited
Primary Brain Tumor
Impact of the Development of Pediatric Palliative Care
Despite medical advances, cancer remains the leading cause of death by disease in children. Brain tumors are the second most common cause of cancer in children after leukemia, representing 25% of pediatric cancers.
- Trial name
- PTB (NCT05660499)
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Strasbourg, France
Esophageal Cancer
trūFreeze® Palliative Esophageal Cancer
Prospective, open label, non-controlled single arm, multi-center study The primary objective is to study the effects of the trūFreeze® Spray Cryotherapy System in a population of subjects who have been diagnosed with persistent…
- Trial name
- NCT03243734
- Testing
- trūFreeze® System spray cryotherapy
- Where
- 10 sites in United States
- Volunteers
- 49 people
- Sponsor
- US Endoscopy Group Inc.
Breast Cancer
mHealth Behavioral Cancer Pain Intervention for Medically Underserved Patients
The efficacy of a mobile health (mHealth) behavioral cancer pain intervention designed to decrease pain and disability for breast cancer patients in medically underserved areas has not been investigated.
- Trial name
- ICAN-NC (NCT04175639)
- Testing
- Mobile Health Pain Coping Skills Training (mPCST)
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Duke University
Paediatric Oncology Palliative Care
Developing a Symptom List for Children With Cancer
Primary Objective The aim of this research study is to develop a comprehensive inventory of symptoms that occur in children with advanced cancer who are receiving a specialist palliative care service.
- Trial name
- NCT02726815
- Testing
- Questionnaire
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Royal Marsden NHS Foundation Trust
Breast Cancer, Metastatic Breast Cancer
Feasibility of Symptom Management for Patients With Metastatic Breast Cancer to Increase Exercise
This study will examine unmet exercise needs among patients with metastatic breast cancer (MBC) at UNC and assess whether participation in Get Real and Heel (GRH) can increase physical activity.
- Trial name
- NCT07313306
- Testing
- The Real and Heel (GRH)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Breast Neoplasms, Syndrome
Development and Usability Evaluation of a Knowledge Graph-Based Symptom Management System for Patients With Breast Cancer Undergoing Chemotherapy
Patients with breast cancer patients undergoing chemotherapy commonly experience multiple co-occurring symptoms that are dynamic, interrelated, and difficult to manage using conventional approaches.
- Trial name
- KG-SMR-BC (NCT07495358)
- Testing
- Knowledge Graph-Based Symptom Management System
- Volunteers
- 30 people
- Sponsor
- Capital Medical University
Palliative Care
Radiotherapy in Palliation of Advanced Pelvic Cancer
The study wants to define the safety and efficacy of a short-course radiation therapy in patients with symptomatic advanced pelvic cancer.
- Trial name
- NCT03947268
- Testing
- Short course radiotherapy
- Volunteers
- 25 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Mental Health Issue, PTSD
AIMS Medical Outcomes Study
This epidemiologic research is being conducted as an observational prospective case series outcomes study of the use of advanced integrative specialty medical care and its effect on adult and pediatric patients with chronic or…
- Conditions
- Mental Health Issue, PTSD, Pain, Chronic Pain
- Trial name
- AMOS (NCT04512755)
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Advanced Integrative Medical Science Institute
Altered Taste
TQ-PAL Development and Validation
Taste problems are common among patients with advanced cancer. These symptoms can affect the pleasure of eating and drinking, reduce dietary intake, cause low mood, and a lower quality of life.
- Trial name
- NCT06588933
- Testing
- completion of a questionnaire
- Where
- Ireland
- Volunteers
- 200 people
- Sponsor
- Prof Andrew Davies
Esophageal Neoplasm, Gastric Neoplasm
Study of Additive Omega-3 Fish Oil to Palliative Chemotherapy to Treat Oesophagogastric Cancer
The prognosis for patients with advanced oesophago-gastric cancer is poor. Approximately 16,000 patients in the United Kingdom die from the disease.
- Trial name
- NCT01870791
- Testing
- Omegaven
- Where
- United Kingdom
- Volunteers
- 21 people
- Sponsor
- University Hospitals, Leicester
Lung Cancer
Mistletoe in Treating Patients With Advanced Non-Small Cell Lung Cancer Who Are Receiving Palliative Chemotherapy
RATIONALE: Mistletoe may help the body build an immune response and may improve quality of life to help patients live more comfortably.
- Trial name
- NCT00052325
- Testing
- mistletoe extract
- Where
- United States
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
Biliary Tract Neoplasms, Pancreatic Neoplasms
RCT Steel (Wallstent®) vs Nitinol (Wallflex®) Bile Duct Stent for Palliation of Malignant Obstruction
Less than 20% of patients with malignant distal bile duct (BD) obstruction (often pancreatic cancer) are suitable for resection surgery.In the rest,palliation treatment comes into focus.
- Conditions
- Biliary Tract Neoplasms, Pancreatic Neoplasms, Stent Occlusion
- Trial name
- NCT00980889
- Testing
- Steel, Nitinol
- Where
- 11 sites in Sweden
- Volunteers
- 400 people
- Sponsor
- Stockholm South General Hospital
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