Clinical trials: Palliative Cancer
Colorectal Cancer
Living With Colorectal Cancer: Patient and Caregiver Experience
This observational study will gather outcome and experience data of patients living with advanced colorectal cancer and their caregivers.
- Trial name
- NCT03572101
- Where
- 3 sites in Canada
- Volunteers
- 280 people
- Sponsor
- University of Calgary
Cancer
Novel Palliative Care Model for Advanced Cancer Patients: A Randomized Controlled Trial Study
This is a randomized controlled trial of the 'Supportive and Palliative care Review Kit in Locations Everywhere' (SPARKLE) intervention, an outpatient-based model of early palliative care.
- Trial name
- SPARKLE2 (NCT04242251)
- Testing
- SPARKLE Model of care
- Where
- Singapore
- Volunteers
- 239 people, healthy volunteers welcome
- Sponsor
- National Cancer Centre, Singapore
Cancer Pain, Palliative Care
e-Natureza Blue Care: Nature-based Virtual Reality and Pain Perception
This randomized clinical trial aims to evaluate the effectiveness of immersive nature-based virtual reality in managing chronic pain among oncology patients.
- Trial name
- e-NatBlue (NCT07053228)
- Testing
- Nature-based virtual reality, Standard Pain Management
- Where
- Brazil
- Volunteers
- 130 people
- Sponsor
- Hospital Israelita Albert Einstein
Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm
Psilocybin With Psychotherapy for Improving Chronic Pain in Cancer Patients Requiring Opioids
This phase II trial studies whether psilocybin with psychotherapy is safe and if it works for improving chronic pain in cancer patients who require opioids to manage their pain.
- Trial name
- NCT06827054
- Testing
- Biospecimen Collection, Functional Magnetic Resonance Imaging, Interview
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Roswell Park Cancer Institute
Advanced Cancer
A Structured Early Palliative Care Intervention for Patients With Advanced Cancer - a Randomized Controlled Trial With a Nested Qualitative Study (SENS Trial)
It is assumed that an early palliative care structured by SENS (a systematic, problem-based assessment system) in addition to standard oncology care compared with standard oncology care alone relieves distress in patients with…
- Trial name
- SENS (NCT01983956)
- Testing
- SENS model
- Where
- 3 sites in Switzerland
- Volunteers
- 150 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Lower Extremity Lymphedema
Feasibility and Effectiveness of Lymphedema Education Program After Gynecological Cancer Surgery
This study aims to examine the effect of lower extremity lymphedema prevention training based on the Symptom Management Model on women undergoing gynecological cancer surgery on lymphedema development, quality of life, and…
- Trial name
- NCT06251856
- Testing
- lymphedema education program
- Volunteers
- 28 people
- Sponsor
- Koç University
Palliative Care
Randomized Controlled Trial of Group Psychotherapy Interventions for Cancer Patients
The purpose of this study is to compare two types of group counseling for cancer patients: Meaning-Centered counseling and Supportive counseling.
- Trial name
- NCT00494910
- Testing
- Meaning Centered Group Psychotherapy, Supportive Group Psychotherapy
- Where
- United States
- Volunteers
- 253 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Cancer, End Stage Cancer
Community Health Worker Based Intervention to Improve Palliative Care
The study aims to find out if community health worker (CHW) support will improve palliative care outcomes in African American patients with advanced cancer, by comparing the quality of life of patients who are receiving standard…
- Conditions
- Cancer, End Stage Cancer, Malignancy, Advanced Cancer
- Trial name
- DeCIDE PC (NCT05407844)
- Testing
- Community Health Worker (CHW) based palliative care
- Where
- 4 sites in United States
- Volunteers
- 160 people
- Sponsor
- Wake Forest University Health Sciences
Metastatic Renal Cell Carcinoma Treated With Cabozantinib
Development of a Cabozantinib (Cabometyx) Symptom Management Application for Use in Patients With Renal Cancer
The purpose of this study is to develop an on-line electronic symptom management application that can ultimately be used to improve clinical outcomes in patients with mRCC treated with cabozantinib.
- Trial name
- Cabo App (NCT03867045)
- Testing
- Usability of an electronic symptom management application
- Where
- 2 sites in United States
- Volunteers
- 1 people
- Sponsor
- Duke University
Breast Cancer
mHealth Behavioral Cancer Pain Intervention for Medically Underserved Patients
The efficacy of a mobile health (mHealth) behavioral cancer pain intervention designed to decrease pain and disability for breast cancer patients in medically underserved areas has not been investigated.
- Trial name
- ICAN-NC (NCT04175639)
- Testing
- Mobile Health Pain Coping Skills Training (mPCST)
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Duke University
Palliative Care, Diabetes Mellitus, Type 2
GLYPALCARE STUDY - Multicenter, Randomized Study for Evaluating Continuous Glucose Monitoring (CGM) by Using FreeStyle Libre 2 (FSL2) for Preventing Hyperglycemia/Hypoglycemia Crisis in Advanced Oncological Patients.
Cancer patients with known or newly diagnosed (i.e. iatrogenic) Diabetes Mellitus (DM) in Palliative/Supportive Care will be enrolled. Patients will be randomly assigned to one of two groups.
- Conditions
- Palliative Care, Diabetes Mellitus, Type 2, Diabetes Mellitus, Type 1, Diabetes
- Trial name
- NCT04942756
- Testing
- Continuous Glucose Monitoring, Standard Care
- Where
- 6 sites in Israel, Italy and 1 more
- Volunteers
- 118 people
- Sponsor
- Antea Foundation
Acupressure, Cancer Pain
The Effect of Acupressure and Reiki on Pain and Fatigue Levels
This research was conducted with the aim of determining the effect of levels of pain and fatigue of acupressure and Reiki application on cancer patients receiving palliative care.
- Conditions
- Acupressure, Cancer Pain, Fatigue
- Trial name
- NCT05473845
- Testing
- Acupressure intervention, Reiki intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 156 people
- Sponsor
- Mardin Artuklu University
Biliary Tract Cancer, Periampullary Adenocarcinoma
SOX Sequential S-1 in Advanced Biliary Tract Carcinoma（BTC）and Pancreatic Cancer
This is an exploratory, single-armed, open label study on the efficacy and safety of sequential S-1 therapy after SOX in unresectable metastatic or locally advanced biliary system or periampullary cancer or pancreatic cancer…
- Conditions
- Biliary Tract Cancer, Periampullary Adenocarcinoma, Pancreatic Cancer
- Trial name
- NCT01811277
- Testing
- SOX sequential S-1
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Peking University
Advanced Malignant Neoplasm, Caregiver
Preference of Room Setting and Waiting Time in Patients With Advanced, Locally Advanced, or Metastatic Cancer and Their Caregivers Who Are Seen in the Outpatient Supportive/Palliative Care Center
This trial studies the preference of room setting and waiting time in patients with cancer that has spread to nearby tissue or lymph nodes or other places in the body and their caregivers who are seen in the outpatient…
- Conditions
- Advanced Malignant Neoplasm, Caregiver, Locally Advanced Malignant Neoplasm, Metastatic Malignant Neoplasm
- Trial name
- NCT03671226
- Testing
- Questionnaire Administration
- Where
- United States
- Volunteers
- 406 people
- Sponsor
- M.D. Anderson Cancer Center
Pain
Efficacy of Low Analgesic Doses of Ketamine Associated With Opioids in Refractory Cancer Pain Treatment
Long-term opioid therapy is commonly administered for the management of severe cancer pain. Increasing doses of opioids are titrated against effects until analgesia is achieved or intolerable adverse effects occur.
- Trial name
- KEPAL (NCT01326325)
- Testing
- Ketamine, NaCl
- Where
- France
- Volunteers
- 24 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pancreatic Ductal Adenocarcinoma
Pilot Study Evaluating Broccoli Sprouts in Advanced Pancreatic Cancer [POUDER Trial]
The goal of the POUDER trial is to determine the feasibility of a randomized controlled trial regarding the application of freeze-dried broccoli sprouts rich in sulforaphane and quercetin in patients with advanced pancreatic…
- Trial name
- POUDER (NCT01879878)
- Testing
- Verum, broccoli sprout grain
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Heidelberg University
Esophagus Cancer
Advanced Oesophageal Cancer Study to Compare Quality of Life and Palliation of Dysphagia.
To compare the treatment of gullet cancer with radiotherapy alone and assess the advantage and toxicity of adding chemotherapy. The hypothesis to be tested is as follows: That the addition of chemotherapy to a short course of…
- Trial name
- NCT00193882
- Testing
- Cisplatin, Radiotherapy, 5-Fluorouracil
- Where
- 25 sites in Australia, Canada and 2 more
- Volunteers
- 220 people
- Sponsor
- Trans Tasman Radiation Oncology Group
Metastatic Cancer Rectum
The Role of Short Course of Palliative Radiation in Metastatic Cancer Rectum
Short-course radiotherapy (SCRT), which allows the delivery of 25 Gy in five daily fractions, has emerged as an attractive strategy for rectal cancer treatment.
- Trial name
- NCT06521827
- Testing
- short course radiotherapy
- Volunteers
- 49 people
- Sponsor
- Assiut University
Ketamine, Refractory Cancer Pain
Continuous IntraVenous Infusion of Ketamine in Terminally Ill Cancer Patients
To establish the role of ketamine in hospitalized terminally ill cancer patients with refractory cancer pain, using continuous intravenous infusion of ketamine
- Trial name
- CIVIK (NCT03362073)
- Testing
- Ketamine
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Pusan National University Yangsan Hospital
Non-Small Cell Lung Cancer
Radiation Therapy to Relieve Symptoms in Patients With Advanced Non-Small Cell Lung Cancer (NSCLC)
This study will test the safety of Quad Shot radiation therapy using 2 different treatment schedules to find out what effects, if any, this treatment has on people with advanced NSCLC who are receiving systemic therapy for their…
- Trial name
- NCT04384146
- Testing
- Cyclical Hypofractionated Palliative Radiation (Quad Shot), EORTC QLQ-C30 questionnaire
- Where
- 7 sites in United States
- Volunteers
- 41 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
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