Clinical trials: Palliative Care, Patient Care
Cancer
Prognosis and Survival Estimates in Palliative Therapy
The accuracy of clinical survival estimates is tested in comparison to objective prognostic scores.
- Trial name
- NCT00871520
- Testing
- no specific interventions
- Where
- 3 sites in Germany
- Volunteers
- 612 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
Family Caregiving for a Palliative Patient
Supporting Family Caregivers of Palliative Patients at Home: the Carer Support Needs Assessment Intervention
In this project the investigators will train home care nurses to use the Carer Support Needs Assessment Tool (CSNAT) with a group of family caregivers (intervention group) and then compare the family caregivers' quality of life…
- Trial name
- CSNAT (NCT02261935)
- Testing
- Existing home care nursing practice, Practice support tool intervention
- Where
- Canada
- Volunteers
- 130 people
- Sponsor
- Kelli Stajduhar
Metastatic Cancer, Mobile Health
Mobile Health Technology for Palliative Care Patients
To test the potential and acceptance of wireless activity tracking in palliative care patients leaving hospital care. Explorative study, collaboration project of the Clinic of Radiation-Oncology, University Hospital Zurich and…
- Conditions
- Metastatic Cancer, Mobile Health, Chronic Disease
- Trial name
- NCT03038841
- Testing
- Mobile Health
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- University of Zurich
Critical Illness, Communication
Time Limited Trials to Reduce Non-Beneficial Intensive Care Unit Treatments
Overutilization of intensive care unit (ICU) treatments among patients with advanced medical illnesses and poor prognosis places them at risk for prolonged suffering with minimal anticipated benefit.
- Trial name
- NCT04181294
- Testing
- Family meetings using time limited trials as default ICU communication and care planning approach, Usual practice
- Where
- 3 sites in United States
- Volunteers
- 209 people
- Sponsor
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
End-of-life, Diabetes
Diabetes and Palliative Care
Diabetes prevalence in palliative care is 10-15%. Most hospice patients are treated with insulin. The target glucose level is high in order to decrease the risk of hypoglycemia.
- Conditions
- End-of-life, Diabetes, Terminal Cancer
- Trial name
- DIAPAL (NCT02742701)
- Testing
- diagnosis
- Volunteers
- 180 people
- Sponsor
- Maison Médicale Jeanne Garnier
Depression
Evaluation of the Initial Prescription of Ketamine and Milnacipran in Depression in Patients With a Progressive Disease
KetaPal is a placebo-controlled randomized trial designed to demonstrate the antidepressant action of ketamine in palliative care situations.
- Trial name
- KETAPAL (NCT02783430)
- Testing
- Ketamine, Milnacipran
- Where
- 9 sites in France
- Volunteers
- 42 people
- Sponsor
- University Hospital, Lille
Cancer
Early Intervention vs. Standard Palliative Care in Improving End-of-Life Care in Advanced Cancer Patients
RATIONALE: Palliative care may help patients with advanced cancer live more comfortably. PURPOSE: This randomized clinical trial is studying an early intervention palliative care program to see how well it works compared to a…
- Trial name
- NCT00253383
- Testing
- counseling intervention, educational intervention, psychosocial assessment and care
- Where
- 2 sites in United States
- Volunteers
- 329 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Palliative Care
Palliative Care For Me (PCforMe)
The purpose of this study is to test the usability of PCforMe, a web-based preparation and engagement tool about palliative care, during a pre-visit pilot trial in outpatient palliative care at the Duke Cancer Institute…
- Trial name
- NCT03874195
- Testing
- Access to PCforMe for review, Access to three nationally-recognized Palliative Care websites for review
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Duke University
Dementia, Chronic Disease
Project to Improve Communication About Serious Illness--Hospital Study: Comparative Effectiveness Trial (Trial 2)
The objective of this protocol is to test the effectiveness of a Jumpstart intervention on patient-centered outcomes for patients with chronic illness by ensuring that they receive care that is concordant with their goals over…
- Conditions
- Dementia, Chronic Disease, Neoplasm Metastasis, Lung Neoplasms
- Trial name
- PICSI-H (NCT04283994)
- Testing
- Survey-based Patient/Clinician Jumpstart, EHR-based Clinician Jumpstart
- Where
- 3 sites in United States
- Volunteers
- 756 people
- Sponsor
- University of Washington
Palliative Care, Disclosure
Increasing the Number of Patients Receiving Information About Transition to End-of-life Care
Introduction: Honest prognostication and information for patients are important parts of end-of-life care. This study examined whether an educational intervention could increase the proportion of patients who received information…
- Trial name
- NCT02091622
- Testing
- Educative intervention
- Where
- Sweden
- Volunteers
- 1,431 people
- Sponsor
- Umeå University
Care, Palliative, Respiratory Failure
RENOVATE Palliative: HFNC vs. Standard Respiratory Support in Patients With Do-Not-Intubate Order and ARF
Randomized clinical trial in which the main objective is to compare High Flow Nasal Cannula (HFNC) versus the standard respiratory care in the alleviation of dyspnea perception in patients with do-not-intubate (DNI) order.
- Trial name
- NCT04269681
- Testing
- High Flow Nasal Cannula, Standard respiratory support
- Where
- Brazil
- Volunteers
- 3 people
- Sponsor
- Hospital do Coracao
Dementia
Palliative Care at Home for Dementia
The proposed project is a randomized controlled trial of a new home-based palliative care program for adults with advanced dementia and their caregivers within the Mount Sinai Health System.
- Trial name
- NCT03798327
- Testing
- Home Palliative Care
- Where
- 4 sites in United States
- Volunteers
- 60 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Advanced Cancers
Perception of Palliative Care Encounter
Objectives: Primary Objective The primary objective is to determine patients' perceptions of the timeliness of their referral to an outpatient palliative care clinic. The secondary objectives are to determine: 1.
- Trial name
- NCT02558257
- Testing
- Survey
- Where
- United States
- Volunteers
- 209 people
- Sponsor
- M.D. Anderson Cancer Center
Heart Failure NYHA Class III, Heart Failure NYHA Class IV
Family Palliative and End-of-Life Care for Advanced Heart Failure
Overall objective is to test whether the 5-weekly family home palliative and end-of-life care (FamPALcare) intervention educational and supportive sessions will improve rural home end-of-life and palliative care (EOLPC) for…
- Trial name
- NCT04153890
- Testing
- FamPALcare
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- West Virginia University
Gastric Cancer, Pancreas Cancer
Early Palliative Care in Patients With Metastatic Upper Gastrointestinal Cancers Treated With First-line Chemotherapy
This prospective, randomized, open-label and multicenter phase III study is aimed to estimate the survival benefit of Early Palliative Care (EPC) combined with standard oncology care including first-line chemotherapy…
- Conditions
- Gastric Cancer, Pancreas Cancer, Bile Duct Cancer, Gastroesophageal Cancer
- Trial name
- EPIC-1511 (NCT02853474)
- Testing
- Early Palliative Care visit, EORTC-QLQ-C30 questionnaire, HADS score
- Where
- 20 sites in France
- Volunteers
- 480 people
- Sponsor
- Centre Oscar Lambret
Opioid Use, Constipation Drug Induced
Study on Quality of Life in Advanced Cancer Patients With Opioid-induced Constipation Treated With Naloxegol
Opioid-Induced Constipation (OIC) is often associated with a compromised quality of life of patients in palliative care (PC) setting.
- Conditions
- Opioid Use, Constipation Drug Induced, Cancer
- Trial name
- NCT04294550
- Testing
- Naloxegol
- Where
- Italy
- Volunteers
- 250 people
- Sponsor
- Fondazione ANT Franco Pannuti ETS
Cachexia; Cancer, Anorexia
Comparison Between Mirtazapine and Megestrol for the Control of Anorexia-cachexia in Cancer Patients in Palliative Care.
Cancer-associated anorexia-cachexia is an insidious syndrome that has a major impact on the patient's quality of life, but is also associated with a significant reduction in survival.
- Trial name
- NCT03283488
- Testing
- Mirtazapine, Megestrol
- Where
- Brazil
- Volunteers
- 52 people
- Sponsor
- University of Sao Paulo
Cancer
A Pilot Study of Structured Palliative Care for Patients Enrolled on Phase I Clinical Trials
The goal of this research study is to find out if providing patients who are enrolled in phase 1 clinical trials with structured supportive care will enable them to continue in the Phase 1 trial longer and improve their quality…
- Trial name
- NCT02543541
- Testing
- Structured palliative care, Standard supportive care
- Where
- United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Case Comprehensive Cancer Center
Constipation, Palliative Care
Effectiveness of Docusate in Preventing/Treating Constipation in Palliative Care Patients
The purpose of this study is to determine if docusate is effective in the treatment of constipation in palliative care patients.
- Trial name
- NCT00902031
- Testing
- Docusate Sodium, Sennoside
- Where
- 3 sites in Canada
- Volunteers
- 70 people
- Sponsor
- University of Alberta
Depressive Symptoms, Depression, Anxiety
Transcranial Magnetic Stimulation for Psychological Distress in Patients With Advanced Illness
Psychological and existential distress are a common cause of suffering among patients nearing the end of life, and a major reason for requesting medical aid in dying.
- Conditions
- Depressive Symptoms, Depression, Anxiety, Psychological Distress, Terminal Illness
- Trial name
- NCT04257227
- Testing
- repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- Canada
- Volunteers
- 13 people
- Sponsor
- Ottawa Hospital Research Institute