Clinical trials: Palliative Care
Cancer, Venous Thromboembolism
Prophylaxis of Venous Thrombo-Embolism in Cancer Patients Under Palliative Care
To determine the efficacy and to measure the complications of prophylactic anticoagulation using low-molecular weight heparin in adult cancer patients under palliative care
- Trial name
- NCT00303407
- Testing
- nadroparin
- Where
- Switzerland
- Sponsor
- University Hospital, Geneva
Cancer
Intervention to Improve Caregiver Palliative Care Knowledge and Attitudes
This randomized clinical trial will assess whether a psychoeducational intervention will improve palliative care knowledge and attitudes among close friends and family members of individuals with cancer.
- Trial name
- NCT05162807
- Testing
- Psychoeducational Video on Palliative Care, Educational Video on Nutrition
- Where
- United States
- Volunteers
- 395 people, healthy volunteers welcome
- Sponsor
- Tulane University
HIV
Palliative Care in People Living With HIV/AIDS: Integrating Into Standard of Care
Our goal is to advance palliative care with persons living with AIDS (PLWA) or life-limiting co-morbidities to decrease suffering and increase quality of life (QOL).
- Trial name
- FACE (NCT01775436)
- Testing
- FAmily-CEntered Advance Care Planning, Healthy Living Control
- Where
- 5 sites in United States
- Volunteers
- 444 people
- Sponsor
- Children's National Research Institute
Palliative Care Referral
Characteristics of Patients in the ICU With Palliative Care Consults in a Tertiary University Hospital
The aim of this retrospective observational single-center cohort study is to investigate the factors associated with palliative care (PC) referral, examine intensive care unit (ICU) involvement before, during, or after the…
- Trial name
- NCT06984471
- Testing
- Palliative care consult
- Where
- Switzerland
- Volunteers
- 532 people
- Sponsor
- University Hospital, Basel, Switzerland
Pain, Retention Disorders, Cognitive
Legacy Intervention Family Enactment (LIFE)
The research activities funded through PAR "Dissemination and Implementation Research in Health" in grant R21NR011112 "Legacy Intervention Family Enactment (LIFE)" have been varied and highly successful.
- Conditions
- Pain, Retention Disorders, Cognitive, Other Chronic Illness, Palliative Care
- Trial name
- LIFE (NCT02007564)
- Testing
- LIFE Intervention
- Where
- United States
- Volunteers
- 164 people
- Sponsor
- University of Alabama, Tuscaloosa
Neoplasms
Immunostimulating Interstitial Laser Thermotherapy in Solid Cancers
Thermotherapy is a technology aiming at destroying tissue, for example tumor tissue. Immunostimulating Interstitial Laser Thermotherapy (imILT) is a specific form of thermotherapy, which, in addition to destroying tumor tissue…
- Trial name
- NCT02690428
- Testing
- Immunostimulating Interstitial Laser Thermotherapy
- Where
- Germany
- Volunteers
- 3 people
- Sponsor
- Clinical Laserthermia Systems AB
Communication, Heart Failure
An Intervention to Improve Implantable Cardioverter-Defibrillator Deactivation Conversations
An Implantable Cardioverter-Defibrillator (ICD) is a device implanted in a patient's chest to monitor the heart rhythm and deliver shocks to terminate potentially lethal arrhythmias when necessary.
- Trial name
- WISDOM (NCT01459744)
- Testing
- Communication training for cardiologists., Control arm
- Where
- 6 sites in United States
- Volunteers
- 562 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Lung Cancer
Stepped Palliative Care Versus Early Integrated Palliative Care in Patients With Advanced Lung Cancer
This research study is evaluating ways to provide palliative care to patients who have recently been diagnosed with lung cancer
- Trial name
- STEP PC (NCT03337399)
- Testing
- Stepped PC, Early Integrated PC
- Where
- 3 sites in United States
- Volunteers
- 507 people
- Sponsor
- Massachusetts General Hospital
Chronically Ill
Hope Promotion Program: Effectiveness in Palliative Patients
This study aims to: I. Develop and pilot test the effectiveness of a Hope Promotion Program compared with the standard treatment protocol, in hope, comfort and quality of life, based on a population of palliative patients…
- Trial name
- HPP (NCT02723799)
- Testing
- Hope Promotion Program (HPP), Standard Treatment Protocol
- Volunteers
- 26 people
- Sponsor
- Instituto Politécnico de Leiria
Esophageal Cancer, Reflux, Gastroesophageal
Evaluating Acid Reflux After Oesophageal Stenting Using Anti-reflux Stents
Incurable oesophageal cancer remains a global problem and in South Africa the vast majority of patients with oesophageal cancer have advanced disease at first presentation and are not curable.
- Trial name
- NCT05303298
- Testing
- Anti-reflux oesophageal stent, Conventional oesophageal stent
- Where
- South Africa
- Volunteers
- 72 people
- Sponsor
- University of Cape Town
Palliative Care
Study to Improve Care for Veterans During Serious Illness
Improving end-of-life care is of critical importance to the VA as it faces an increasingly aging and dying veteran population. Previous work within and outside of the VA has demonstrated serious deficiencies in the quality of…
- Trial name
- NCT00106041
- Testing
- Veterans Integrated Palliative Care Nurse Case Manager
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- US Department of Veterans Affairs
Advanced Heart Failure, Advanced Non-Colorectal Gastrointestinal Cancer
Tier Palliative Care For Patients With Advanced Heart Failure or Cancer
TIER-PC is an adaptive model of delivering palliative care that provides the right level of care to the right patients at the right time.
- Conditions
- Advanced Heart Failure, Advanced Non-Colorectal Gastrointestinal Cancer, Advanced Lung Cancer, Advanced Triple Negative Breast Cancer
- Trial name
- TIER-PC (NCT07391956)
- Testing
- Tier-Palliative Care, Community Health Worker
- Where
- 5 sites in United States
- Volunteers
- 400 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Carcinoma, Renal Cell
Palliative Radiofrequency Ablation in Metastatic Renal Cell Carcinoma Patients
The purpose of this study is to evaluate efficacy and safety of Radiofrequency ablation in metastatic renal cell carcinoma patients with primary tumor less than 5 cm before medical treatment.
- Trial name
- NCT00891475
- Testing
- Radiofrequency ablation; Interferon-alpha, Radiofrequency ablation; Sunitinib maleate, Sunitinib maleate
- Where
- Russia
- Volunteers
- 114 people
- Sponsor
- Kidney Cancer Research Bureau
Question Prompt List, Caregivers
The Effectiveness of Using a Palliative Care QPL on the Selfefficacy and Preparedness of Indonesian Homecare Workers
Foreign studies on caregivers' use of QPL in end-of-life care, decision-making, and satisfaction are mostly conducted with family members who share the same language.
- Conditions
- Question Prompt List, Caregivers, End-of-life Care
- Trial name
- NCT06847828
- Testing
- QPL
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Den,Yu-Yun
Lung Neoplasms
Early Incorporation of Patient and Family to Attention and Care Program in Oncology Versus Standard of Care
There is recent evidence that early palliative care administered to patients helps for their quality of life (QoL). It is however not part of the standard multidisciplinary treatment.
- Trial name
- PACO (NCT01631565)
- Testing
- Early allocation to palliative care, Nutritional counseling, Psychoeducation.
- Where
- Mexico
- Volunteers
- 201 people
- Sponsor
- Instituto Nacional de Cancerologia de Mexico
Pancreas Neoplasms
Docetaxel Plus Oxaliplatin as Therapy in Patients With Pancreatic Cancer
The purpose of this study is to test a combination-therapy of oxaliplatin and docetaxel in patients with metastatic or locally advanced adenocarcinoma of the pancreas after failure of a palliative first line therapy.
- Trial name
- NCT00690300
- Testing
- Docetaxel, Oxaliplatin
- Where
- 5 sites in Germany
- Volunteers
- 44 people
- Sponsor
- University of Ulm
Palliative Cancer
Prophylaxis for Emetogenic radioTherapy With Akynzeo
This phase II, prospective study evaluates whether prophylactic treatment with Akynzeo can reduce nausea and vomiting in patients receiving palliative radiotherapy in which the gastrointestinal GI tract is within the radiation…
- Trial name
- PRÊT (NCT07882966)
- Testing
- Akynzeo
- Where
- Canada
- Volunteers
- 188 people
- Sponsor
- University Health Network, Toronto
Colorectal Cancer
A Clinical Study on the Synergistic Effects of Zhen-Qi-Jie-Du Granules in Palliative Care for Advanced Colorectal Cancer
The goal of this clinical trial is to learn whether Zhen-Qi-Jie-Du Granules combined with chemotherapy works to treat unresectable stage IV microsatellite-stable colorectal cancer in adults.
- Trial name
- NCT07854405
- Testing
- Zhen-Qi-Jie-Du Granules II, Zhen-Qi-Jie-Du Granules I
- Where
- China
- Volunteers
- 1,540 people
- Sponsor
- Jiangsu Famous Medical Technology Co., Ltd.
Advanced Cancer, Terminal Malignant Tumors
Nurses' Competence and Role in Survival Prediction and Prognostic Communication
[Background] Nurses' roles in survival prediction and prognostic communication have historically been limited due to role delineation, lack of formal training, and cultural norms.
- Conditions
- Advanced Cancer, Terminal Malignant Tumors, Hospices
- Trial name
- NCT06962553
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Multiple Sclerosis
Be Cool: An Innovative and Holistic Psychoeducational Program for Multiple Sclerosis Individuals
This observational study aims to investigate the impact of an online psychoeducational program, combined with cooling therapy, nutrition, psychological intervention, and exercise, on the resilience, treatment adherence, symptom…
- Trial name
- BeCool (NCT06248281)
- Testing
- combination of different rehabilitation strategies
- Where
- Greece
- Volunteers
- 30 people
- Sponsor
- University of Thessaly