Clinical trials: Palliative Care
Lung Cancer
Supportive Care for Patients Newly Diagnosed With Lung Cancer
The aims of this project are to assess the feasibility of recruiting patients and delivering a nurse-led telephone based palliative care intervention for patients with newly diagnosed lung cancer and to assess if among patients…
- Trial name
- NCT01883986
- Testing
- Palliative Care
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- VA Office of Research and Development
Biliary Strictures Caused by Malignant Neoplasms
Study of the WallFlex™ Biliary Partially-covered Stent for the Palliative Treatment of Malignant Bile Duct Obstruction
This is a a prospective study of the WallFlex™ Biliary Partially-covered Stent designed to collect data to support regulatory clearance by the FDA in the United States and to determine the functionality of the WallFlex™ Biliary…
- Trial name
- NCT00713427
- Testing
- WallFlex™ Biliary Partially-Covered Stent
- Where
- 6 sites in Belgium, France and 4 more
- Volunteers
- 70 people
- Sponsor
- Boston Scientific Corporation
Cholestasis, Extrahepatic
A Study of the WallFlex™ Biliary Fully-covered Stent for the Palliative Treatment of Malignant Bile Duct Obstruction
The overall objective of this study is to assess the functionality of the WallFlex™ Biliary Fully-covered stent as a palliative treatment for malignant bile duct obstruction.
- Trial name
- NCT00433771
- Testing
- WallFlex™ Biliary Fully Covered Metal Stent placement
- Where
- 10 sites in United States
- Volunteers
- 74 people
- Sponsor
- Boston Scientific Corporation
Upper Gingival Squamous Cell Carcinoma
Role of FCγRIIIA and FCγRIIA Receptor Polymorphisms
Hypothesis: Cetuximab, an anti-EGFR antibody, is used with radiotherapy in the treatment of locally advanced and inoperable upper aerodigestive tract cancers.
- Trial name
- FCR-VADS (NCT01827956)
- Testing
- Cetuximab
- Where
- France
- Volunteers
- 121 people
- Sponsor
- Institut Bergonié
Active Cancer, Active Cancer Treatment
STAMP+CBT mHealth for Cancer Pain
The purpose of this study is to test whether a mobile application developed to help people with cancer pain is useful and helpful to patients with cancer.
- Conditions
- Active Cancer, Active Cancer Treatment, Advanced Cancer, Palliative Care
- Trial name
- NCT05403801
- Testing
- STAMP+CBT application
- Where
- 3 sites in United States
- Volunteers
- 10 people
- Sponsor
- Dana-Farber Cancer Institute
COPD, Heart Failure
Personalized Experiences to Inform Improved Communication for Minorities With Life Limiting Illness
The purpose of this research is to develop patient-centered palliative care interventions to improve patient-provider communication and Quality of Life (QoL) of ethnic and racial minority patients living with life-limiting…
- Conditions
- COPD, Heart Failure, Cancer
- Trial name
- NCT03391115
- Testing
- Storytelling Intervention for Patient Participants, Storytelling Intervention for Nurse Participants
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Malignant Neoplasm, Metastatic Malignant Neoplasm in the Bone
Palliative Radiation Therapy in Reducing Pain in Patients With Bone Metastasis
This randomized phase II trial studies how well palliative radiation therapy works in reducing pain in patients with cancer that has spread from the original (primary) tumor to the bone (bone metastasis).
- Conditions
- Malignant Neoplasm, Metastatic Malignant Neoplasm in the Bone, Pain
- Trial name
- NCT02699697
- Testing
- External Beam Radiation Therapy, Palliative Radiation Therapy, Quality-of-Life Assessment
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Wake Forest University Health Sciences
Metastatic Melanoma
Radiation and Combination Immunotherapy for Melanoma
This is a Phase 2 study designed to evaluate the combination of checkpoint blockade and aldesleukin (IL-2) therapy after a course of standard of care palliative radiation in the management of unresectable metastatic melanoma.
- Trial name
- NCT03850691
- Testing
- Aldesleukin: All Patients, Nivolumab: Cohort 1 (Cutaneous), Nivolumab: Cohort 2 (Ocular)
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Masonic Cancer Center, University of Minnesota
Palliative Care
Technology-enhanced Transitional Palliative Care for Family Caregivers
The purpose of this study is to evaluate the effect and cost of technology-enhanced transitional palliative care on family caregivers who provide care to a loved one after a hospitalization.
- Trial name
- NCT03339271
- Testing
- Technology-Enhanced Support, Usual Care Support
- Where
- United States
- Volunteers
- 384 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Bone Metastases
Lazanda in Cancer Patients Receiving Palliative Radiation
Advanced cancer patients often require palliative (pain relieving) radiotherapy to treat cancer-related symptoms. The delivery of radiation requires patients to lie still on a hard flat surface, which can result in significant…
- Trial name
- NCT03071744
- Testing
- Lazanda
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Joseph Ma
Cancer
Predictive Analytics and Behavioral Nudges to Improve Palliative Care in Advanced Cancer
Patients with advanced cancer suffer from high symptom burden and aggressive end-of-life care. Early specialty palliative care is an evidence-based practice that improves symptom burden, quality of life, and survival in advanced…
- Trial name
- NCT05590962
- Testing
- EHR Nudge
- Where
- United States
- Volunteers
- 562 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Hepatocellular Carcinoma, Metastasis
Effect of Colchicine for the Palliative Management of Hepatocellular Carcinoma
This trial is to evaluate the potential of colchicine for the palliative management of hepatocellular carcinoma patients with distant metastasis or large vessel invasion using the Department of Health R.O.C.
- Conditions
- Hepatocellular Carcinoma, Metastasis, Invasion
- Trial name
- NCT01935700
- Testing
- Colchicine
- Where
- Taiwan
- Volunteers
- 15 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Chronic Disease, Neoplasm Metastasis
Facilitating Communication Study
This study is a randomized clinical trial of an intervention to improve outcomes for patients and their family by using ICU nurse facilitators to support, model, and teach communication strategies that enable patients and their…
- Conditions
- Chronic Disease, Neoplasm Metastasis, Lung Neoplasm, Pulmonary Disease, Chronic Obstructive
- Trial name
- FCS2 (NCT03721952)
- Testing
- Facilitator-Based Intervention
- Where
- 3 sites in United States
- Volunteers
- 977 people
- Sponsor
- University of Washington
Breast Cancer, Stage IV Breast Cancer
Early Surgery or Standard Palliative Therapy in Treating Patients With Stage IV Breast Cancer
RATIONALE: The primary tumor might be a source of re-seeding of distant sites and therefore elimination of this source of metastasizing cells by early local therapy may be of benefit.
- Trial name
- NCT01242800
- Testing
- palliative surgery, therapeutic conventional surgery, palliative radiation therapy
- Where
- 377 sites in United States, Canada and 3 more
- Volunteers
- 390 people
- Sponsor
- Eastern Cooperative Oncology Group
Cancer Terminal
Palliative Care for Elderly Outpatients
Our long-term goal is to improve spiritual care outcomes for elderly patients with cancer. The study team will use a spiritual intervention, Dignity Therapy (DT), to help these patients maintain pride, find spiritual comfort…
- Trial name
- NCT03209440
- Testing
- Dignity Therapy - Nurse Led, Usual care, Dignity Therapy - Chaplain Led
- Where
- United States
- Volunteers
- 579 people
- Sponsor
- University of Florida
Distal Bile Duct Obstruction
Covered vs Uncovered Metal Stents for Palliative Biliary Decompression in Inoperable Malignant Distal Bile Duct Obstruction
The purpose of this study is to compare the rate of long-term stent failure, defined as need for repeat biliary intervention following placement of C-SEMS vs U-SEMS for palliation of inoperable malignant distal bile duct…
- Trial name
- NCT01905384
- Testing
- Covered Self-expanding metal biliary stents (C-SEMS), Uncovered Self-expanding metal biliary stents (U-SEMS)
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- Vanderbilt University Medical Center
Gastrointestinal Cancer
Perioperative Palliative Care Surrounding Cancer Surgery for Patients & Their Family Members
The study goal is to compare surgeon-palliative care team co-management, versus surgeon alone management, of patients and family members preparing for major upper gastrointestinal cancer surgery.
- Trial name
- PERIOP-PC (NCT03611309)
- Testing
- Surgeon-palliative care team co management, Surgeon team alone management
- Where
- 5 sites in United States
- Volunteers
- 379 people
- Sponsor
- Stanford University
Parent-Child Relations, Cancer
Cancer Parenting Program for the Enhancement of the Quality of Life of Patients With Advanced Cancer and Their Children
This trial examines the usefulness of two educational programs for parents with late-stage cancer who have a 5 - 17 year old child.
- Conditions
- Parent-Child Relations, Cancer, Survivorship, Hematopoietic and Lymphoid System Neoplasm
- Trial name
- EC-PC (NCT05477784)
- Testing
- Group 1: Educational counseling intervention, Group II Active Comparator
- Where
- 2 sites in United States
- Volunteers
- 174 people
- Sponsor
- University of Washington
COPD
Nurse Coach-Led Early Palliative Care for Older Adults With COPD and Their Care Partners: The Project EPIC Pilot RCT
Chronic obstructive pulmonary disease (COPD) is the third leading cause of death in older Americans. COPD increases in frequency with age, and older adults with COPD often have significant unmet geriatrics-palliative care needs…
- Trial name
- NCT05040386
- Testing
- EPIC (Empower People to Independence in COPD), Usual Care
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Alabama at Birmingham
Pancreatic Cancer, Periampullary Adenocarcinoma
Palliative Stereotactic Radiation for Pancreatic or Periampullary Adenocarcinoma
The investigators are looking to see if a certain dose of stereotactic body radiation therapy (SBRT) may be a viable treatment option for recurrent or residual pancreatic or periampullary adenocarcinoma.
- Trial name
- NCT01781728
- Testing
- Stereotactic Body Radiation Therapy (SBRT)
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins