Clinical trials: Pancreas Inflamed
Acute Pancreatitis, Fecal Microbiota Transplantation
Fecal Microbiota Transplantation for Pancreatitis With Infectious Complications(FMTPIC)
Infectious complications are responsible for most of deaths in acute pancreatitis.Intestinal barrier dysfunction and increased intestinal permeability was associated with bacterial translocation which is believed to prompted…
- Conditions
- Acute Pancreatitis, Fecal Microbiota Transplantation, Bacterial Translocation, Infectious Complications
- Trial name
- NCT02318147
- Testing
- Fecal Microbiota Transplantation, The traditional treatment
- Where
- China
- Volunteers
- 60 people
- Sponsor
- The First Affiliated Hospital of Nanchang University
Immunoglobulin G Subclass 4 Related Disease, IgG4-related Disease
Treatment of IgG4-Related Disease With Revlimid and Rituximab
Among persons with Immunoglobulin G subclass 4 Related Disease (IgG4)-related disease who have persistent or recurrent disease despite standard therapies, does combination therapy with rituximab and revlimid cause a sustained…
- Conditions
- Immunoglobulin G Subclass 4 Related Disease, IgG4-related Disease, Autoimmune Pancreatitis, IgG4-related Sclerosing Cholangitis
- Trial name
- TIGR2 (NCT02705638)
- Testing
- Rituximab, Lenalidomide
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Mayo Clinic
Idiopathic Pancreatitis
Laparoscopic Cholecystectomy in Idiopathic Pancreatitis
The causes of acute pancreatitis in Finland are alcohol overuse (60%), cholecystolithiasis (20%) and idiopathic (i.e. etiology unknown)(20%).
- Trial name
- NCT00784355
- Testing
- Laparoscopic cholecystectomy
- Where
- Finland
- Volunteers
- 200 people
- Sponsor
- Kuopio University Hospital
Acute Pancreatitis
MIld to MOderate Acute Pancreatitis: Early naSogastric Tube Feeding Compared With pAncreas Rest (MIMOSA)
Pain relapse during oral refeeding occurs in at least one-fifth of patients with acute pancreatitis. The study hypothesis is that early administered enteral tube feeding might reduce a risk of pain relapse and shorten the length…
- Trial name
- MIMOSA (NCT01128478)
- Testing
- Enteral tube feeding
- Where
- New Zealand
- Volunteers
- 35 people
- Sponsor
- University of Auckland, New Zealand
Pancreatic Ductal Adenocarcinoma, Pancreatitis, Chronic
Artificial Intelligence in EUS for Diagnosing Pancreatic Solid Lesions
We aim to develop an EUS-AI model which can facilitate clinical diagnosis by analyzing EUS pictures and clinical parameters of patients.
- Conditions
- Pancreatic Ductal Adenocarcinoma, Pancreatitis, Chronic, Pancreatic Neuroendocrine Tumor, Autoimmune Pancreatitis
- Trial name
- NCT05476978
- Testing
- EUS-AI model
- Where
- China
- Volunteers
- 130 people
- Sponsor
- Huazhong University of Science and Technology
Acute Necrotizing Pancreatitis
CMV Reactivation in Acute Necrotizing Pancreatitis
Patients with the diagnosis of acute necrotizing pancreatitis (ANP) present with a wide spectrum of severity. These patients frequently require intensive care management.
- Trial name
- NCT05898048
- Where
- India
- Volunteers
- 41 people
- Sponsor
- Sanjay Gandhi Postgraduate Institute of Medical Sciences
Pancreatitis
Genetic Analysis for Predicting of Relapse During Steroid Treatment for Autoimmune Pancreatitis (AIP)
To determine whether certain alleles or haplotypes of major histocompatibility complex gene are associated with AIP in Korean population, we undertook this study with high-resolution typing for HLA (sequence-based typing).
- Trial name
- NCT00444444
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Asan Medical Center
Acute Biliary Pancreatitis
Acute Biliary Pancreatitis - Optimal Time for Cholecystectomy
In patients with mild gallstone pancreatitis, early cholecystectomy within 48 hours might reduce the risk of recurrent gallstone-related complications, compared with the more commonly used strategy in our locality of conservative…
- Trial name
- NCT03085407
- Testing
- early cholecystectomy, delayed cholecystectomy
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- South Valley University
Pancreatic Neoplasms, Cholangiocarcinoma
Biliary Tissue Sampling Using a Cytology Brush or the GIUM Catheter
Introduction In patients with a biliary obstruction, tissue is acquired immediately before drainage during endoscopic retrograde cholangio-pancreatography (ERCP).
- Conditions
- Pancreatic Neoplasms, Cholangiocarcinoma, Pancreatitis
- Trial name
- NCT00160836
- Testing
- Tissue sampling ("G.I.U.M." catheter)
- Where
- 3 sites in Argentina
- Volunteers
- 68 people
- Sponsor
- University Hospital, Geneva
Visceral Pain, Pancreatitis
Neurophysiological Effects on tPCS and tDCS on Healthy Subjects and on Patients With Chronic Visceral Pain
This study investigates comparing the effects of transcranial Pulsed Current Stimulation and transcranial Direct Current Stimulation (tDCS) (Soterix ©) and their combination on neurophysiological outcomes on healthy subjects as…
- Conditions
- Visceral Pain, Pancreatitis, Pelvic Pain
- Trial name
- NCT02497196
- Testing
- Active tPCS, Active tDCS
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Spaulding Rehabilitation Hospital
Pancreatitis
Decrease of Recurrent Pancreatitis
Retrospective studies have shown, that about half of the patients will have a recurrent episode after the first acute alcoholic pancreatitis.
- Trial name
- NCT00534534
- Testing
- Repeated behavioural intervention without any drugs
- Where
- Finland
- Volunteers
- 120 people
- Sponsor
- Tampere University
Chronic Pancreatitis
Italian Registry Chronic Pancreatitis
ITARECIPE is a multicenter national registry designed to study the diagnosis and evolution of Chronic Pancreatitis
- Trial name
- ITARECIPE (NCT05733130)
- Where
- Italy
- Volunteers
- 1,500 people
- Sponsor
- Associazione Italiana per lo Studio del Pancreas
Pancreatitis
SARcopenia in Patients With ChrOnic PANcreatitis: the SARCOPAN Study
Sarcopenia is a complex multifactorial syndrome which could be present in older age (primary sarcopenia) or earlier in chronic disease (secondary sarcopenia).
- Trial name
- SARCOPAN (NCT06092307)
- Testing
- Bioelectrical impedance, Handgrip strength test, muscle ultrasound.
- Where
- Italy
- Volunteers
- 98 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Pancreatitis, Acute
Safety and Tolerability of Pirfenidone in Acute Pancreatitis
The goal of the current pilot clinical trial is to evaluate the safety and tolerability of pirfenidone in patients with predicted moderately severe and severe acute pancreatitis.
- Trial name
- NCT05350371
- Testing
- Pirfenidone Oral Tablet
- Where
- 2 sites in United States
- Volunteers
- 1 people
- Sponsor
- University of Alabama at Birmingham
Chronic Pancreatitis, Healthy Volunteers
BreathID® Test: A Non-invasive Modality to Detect Pancreatic Exocrine Insufficiency
13C breath di-peptide tests are an effective non-invasive tool to detect pancreatic exocrine function in patients with Chronic Pancreatitis.
- Trial name
- NCT01259544
- Testing
- benzoyl-L-tyrosyl-[1-13C]alanine (Bz-Tyr-Ala)
- Where
- India
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Meridian Bioscience, Inc.
Acute Pancreatitis, Acute Pancreatitis With Infected Necrosis
Pancreatitis - Microbiome as Predictor of Severity II
The goal of this observational study is to evaluate the orointestinal microbiome and microbial derived metabolome in patients suffering from acute pancreatitis as a biomarker for severity.
- Trial name
- P-MAPS II (NCT06508502)
- Where
- Germany
- Volunteers
- 700 people
- Sponsor
- University Medical Center Goettingen
Acute Pancreatitis, Organ Failure, Multiple
Elevated Stearoyl-CoA Desaturase-1 Expression Predicts the Disease Severity of Severe Acute Pancreatitis
In this study, the investgatiors aimed to investigate the associations between serum levels of stearoyl-CoA desaturase-1（SCD-1） and the disease severity as well as the presence of adverse clinical events, such as local…
- Trial name
- NCT03282253
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Nanjing University School of Medicine
Pancreatitis
Acute Pancreatitis Patient Registry To Examine Novel Therapies In Clinical Experiences 2
This study is an ancillary of APPRENTICE. This will be the international based study.
- Trial name
- APPRENTICE2 (NCT03075631)
- Testing
- Questionnaire
- Where
- United States
- Volunteers
- 1,183 people
- Sponsor
- University of Pittsburgh
Pancreatitis, Chronic
Radiomic fEatures of Pancreas From Contrast Enhanced CT Image Predict One-Year RecUrrence Risk of Acute PancReatitis
One-year recurrence rate of acute pancreatitis at about 20%. 36% of the patients with recurrent acute pancreatitis will develop into chronic pancreatitis.
- Trial name
- RECUR (NCT05778929)
- Testing
- Radiomics Model
- Volunteers
- 694 people
- Sponsor
- Peking University People's Hospital
Post-ERCP Pancreatitis
Comparison Of Loop-Tip Wire Vs Tradictional Technique In The Cannulation Of The Common Bile Duct
Selective cannulation of common bile duct (CBD) by insertion of a guide-wire seems to be associated with fewer complications and post-ERCP (Endoscopic retrograde cholangiopancreatography) pancreatitis (PEP) rate than the…
- Trial name
- NCT01771419
- Testing
- Loop-tip wire (Cook Medical) for the cannulation of the CBD, Cannulotome CT-25mm Cook Medical
- Where
- Italy
- Volunteers
- 320 people
- Sponsor
- Hospital San Paolo