Clinical trials: Pancreatic Cancer Pain
Cancer Pain, Visceral Pain
Virtual Reality for GI Cancer Pain to Improve Patient Reported Outcomes
Patients with digestive tract malignancy often experience severe and unremitting abdominal pain that negatively affects physical, emotional, and social function, as well as health related quality of life (HRQOL).
- Conditions
- Cancer Pain, Visceral Pain, Gastrointestinal Neoplasms, Cancer of Gastrointestinal Tract
- Trial name
- NCT04907643
- Testing
- PICO G2 4k
- Where
- United States
- Volunteers
- 360 people
- Sponsor
- Cedars-Sinai Medical Center
Pancreas, Cancer
Magnetic Resonance-guided High-intensity Focused Ultrasound Treatment of Locally Advanced Pancreatic Cancer
Patients with unresectable pancreatic cancer in most of cases cannot benefit from percutaneous ablation modalities, due to high risk of procedure-related complications.
- Conditions
- Pancreas, Cancer, Locally Advanced Pancreatic Cancer, Non-invasive Treatment
- Trial name
- NCT01786850
- Testing
- Magnetic Resonance-guided High-intensity Focused Ultrasound (MRgFUS)
- Where
- Italy
- Sponsor
- University of Roma La Sapienza
Surgery, Stomach Cancer
TRANScriptional Pathways Of Surgical Pain Modulated by Music Therapy Exposure (TRANSPOSE)
Participants may take part in this study if they are scheduled to undergo a surgery that meets the following: (1) traditional open surgery via laparotomy, (2) length of surgery >3 hours, and (3) curative-intent surgical resection…
- Conditions
- Surgery, Stomach Cancer, Pancreas Cancer, Bile Duct Cancer
- Trial name
- NCT07653594
- Testing
- Music-assisted relaxation and imagery (MARI)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Case Comprehensive Cancer Center
Pancreatic Cancer
EUS-guided Celiac Plexus Neurolysis for the Treatment of Abdominal Pain in Pancreatic Cancer
Studies have shown that injecting local anesthetics in areas rich in blood vessels increases the risk of drug injection into blood vessels by mistake and increases the systemic absorption of drugs, which may increase the…
- Trial name
- NCT03940027
- Testing
- EUS-guided celiac plexus neurolysis
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Changhai Hospital
Intractable Abdominal Pain Secondary to Inoperable Malignancy
EUS-guided CGN for Inoperable Cancer
Patients suffering from pancreatic cancer are associated with a poor prognosis and survival of less than one year is expected in inoperable tumours. Management of these patients would be towards palliation of symptoms.
- Trial name
- NCT02356640
- Testing
- EUS-guided celiac ganglion neurolysis, Percutaneous celiac plexus neurolysis, Olympus UM 2000
- Where
- China
- Volunteers
- 3 people
- Sponsor
- Chinese University of Hong Kong
Ductal Adenocarcinoma of Pancreas, Pancreatectomy
Patients With Pancreatic Tumor: Use of an App to Monitor Progress in a Simple and Intuitive Way by Periodically Completing Targeted Questionnaires and Providing Educational and Informational Content (PancreasPlus).
Caring for people with pancreatic cancer requires good coordination between hospital care and care at home, with different healthcare professionals working closely together.
- Conditions
- Ductal Adenocarcinoma of Pancreas, Pancreatectomy, Caregiver, Nutritional Evaluation
- Trial name
- NCT07532590
- Testing
- use of PancreasPlus app
- Where
- 2 sites in Italy
- Volunteers
- 185 people
- Sponsor
- Casa di Cura Dott. Pederzoli
Postoperative Pain, Postoperative Complications
PERiX: Comparison of Efficacy Between Placement of Epidural Catheters X-ray Guided and LOS Technique
The use of epidural catheters for postoperative analgesia in pancreatic surgery is recommended by the guidelines of the ERAS society.
- Conditions
- Postoperative Pain, Postoperative Complications, Pancreatic Cancer, Haemodynamic Instability
- Trial name
- PERiX (NCT03685370)
- Testing
- LOS, X-ray placement
- Where
- Italy
- Volunteers
- 154 people
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
Pancreatic Cancer, Chronic Pancreatitis
Intravenous Lidocaine for Pain Associated With Pancreatic Cancer and Chronic Pancreatitis
Pain is a major clinical problem for many patients with pancreatic cancer and chronic pancreatitis (CP).In pancreatic cancer, nearly 75% of patients suffer from pain at the time of diagnosis, with over 90% of patients in advanced…
- Trial name
- LIDOPAN (NCT05906615)
- Testing
- Lidocaine IV
- Where
- Netherlands
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Obesity, Obesity, Morbid
Biological Sample Repository for Gastrointestinal Disorders
The goal of this observational study has the purpose of collecting biological samples from obese patients undergoing evaluation for weight loss by means of medical or endoscopic therapies; and of post bariatric surgery patients…
- Conditions
- Obesity, Obesity, Morbid, Obesity, Primary, Gastro-Intestinal Disorder
- Trial name
- NCT05874726
- Testing
- Blood Collection, Urine Collection, Tissue Sample Collection
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Pichamol Jirapinyo, MD, MPH
Pain, Pancreatic Cancer
Endoscopic Ultrasound (EUS) Guided-Celiac Plexus Neurolysis (CPN) in Unresectable Pancreatic Cancer
The purpose of this study is to examine endoscopic ultrasound guided celiac plexus neurolysis (CPN) with analgesic therapy in patients with unresectable pancreatic cancer as it applies to decreasing the severity of abdominal pain…
- Trial name
- NCT00968175
- Testing
- Ultrasound guided celiac plexus neurolysis (CPN)
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- University of Alabama at Birmingham
Pancreatic Cancer
Efficacy of TEAS on Postoperative Pain and Recovery in Patients Undergoing Pancreatectomy
The purpose of this study is to access the effect of transcutaneous electrical acupoint stimulation on postoperative pain in patients undergoing pancreatectomy
- Trial name
- NCT06541561
- Testing
- transcutaneous electrical acupoint stimulation
- Volunteers
- 132 people
- Sponsor
- West China Hospital
Pancreatic Cancer, Pain
Invasive Treatment of Pain Associated With Pancreatic Cancer on Different Levels of WHO Analgesic Ladder
Pancreatic cancer is a difficult to treat disease, mainly due to the fact that diagnosis is made usually in the late stage of this condition.
- Trial name
- NCT02424279
- Testing
- Splanchnicectomy
- Where
- Poland
- Volunteers
- 90 people
- Sponsor
- Medical University of Gdansk
Pancreatic Cancer
Endoscopic Pancreatic Duct Stenting for Relief of Obstructive Pain in Patients With Pancreatic Cancer
This research is being done to assess the effects of pancreatic duct stenting on relief of obstructive pain (pain due to outflow obstruction of main pancreatic duct) caused by pancreatic cancer.
- Trial name
- NCT01895790
- Testing
- Pancreatic Duct Stent Placement
- Where
- United States
- Sponsor
- Johns Hopkins University
Pancreatic Cancer Non-resectable, Tumor Pancreas
Upfront EUS CGN/CPN vs Conventional Step up Approach for Inoperable Painful Pancreatic Cancer
Patients with unresectable pancreatic cancer are often demoralized by intractable, persistent and incapacitating pain. It must be managed aggressively and strong opioids are recommended as the mainstay of treatment.
- Conditions
- Pancreatic Cancer Non-resectable, Tumor Pancreas, Pain Cancer
- Trial name
- NCT06160323
- Testing
- EUS-guided coeliac ganglion neurolysis / celiac plexus neurolysis
- Where
- Hong Kong
- Volunteers
- 94 people
- Sponsor
- Chinese University of Hong Kong
Pancreatic Cancer, Visceral Pain
Efficacy Of Pregabalin In The Treatment Of Pancreatic Cancer Pain. A Randomized Controlled Double-Blind, Parallel Group Study
This is a randomized, double blind controlled, parallel arms trial, aimed to assess the efficacy of pregabalin on pancreatic cancer induced abdominal pain.
- Trial name
- PANPAIN/1 (NCT01768988)
- Testing
- Pregabalin
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Parc de Salut Mar
Unresectable Pancreatic Cancer
Bilateral Thoracoscopic Splanchnicectomy for Pain Relief in Patients With Unresectable Pancreatic Cancer
This study aims to compare the efficacy of bilateral thoracoscopic splanchnicectomy (BTS) to conventional narcotic analgesia for control of abdominal pain in patients with pancreatic ductal adenocarcinoma not amenable to surgical…
- Trial name
- NCT03117556
- Testing
- Bilateral Thoracoscopic Splanchnicectomy
- Where
- 2 sites in United States
- Sponsor
- University of Louisville
Pancreatic Ductal Adenocarcinoma, Pain, Acute
Ketamine-assisted Therapy for Advanced GI Cancer
This clinical trial evaluates whether it is possible to use a single dose of ketamine in combination with talk therapy to treat moderate to severe demoralization in patients with stage 3 or 4 gastrointestinal (GI) cancers who…
- Conditions
- Pancreatic Ductal Adenocarcinoma, Pain, Acute, Gastrointestinal Cancers, Demoralization
- Trial name
- NCT06077487
- Testing
- Ketamine, Ketamine Injectable Product, Meaning and Purpose therapy
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Brian Anderson, MD
Pancreatic Cancer, Pain
Efficacy and Mechanisms of Acupuncture for Patients With Advanced Pancreatic Cancer Pain
This study compares the effect of acupuncture and placebo acupuncture on advanced pancreatic cancer pain and then investigates its potential mechanism of peripheral blood.
- Trial name
- NCT02510066
- Testing
- Acupuncture
- Where
- China
- Volunteers
- 62 people
- Sponsor
- Shanghai Cancer Hospital, China
Hepatocellular Carcinoma, Pancreas Cancer
Scheduled Meditation for Improving Postoperative Outcomes in Patients Undergoing Pancreatectomy
This clinical trial tests the feasibility and how well a scheduled meditation intervention works to improve postoperative outcomes such as pain, anxiety, insomnia, stress and mobility for patients undergoing pancreatectomy.
- Conditions
- Hepatocellular Carcinoma, Pancreas Cancer, Biliary Tract Neoplasms
- Trial name
- NCT07608458
- Testing
- Actigraphy, Online Mindfulness Meditation, Smartphone Application-based Intervention
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- City of Hope Medical Center
Rheumatoid Arthritis, Ankylosing Spondylitis
PatientSpot Formerly Known as ArthritisPower
Patient Power is a patient research network and database (registry) to collect prospective information about demographics, self-reported diagnoses and medications, and willingness to participate in research from participants with…
- Conditions
- Rheumatoid Arthritis, Ankylosing Spondylitis, Fibromyalgia, Gout
- Trial name
- NCT03840928
- Where
- United States
- Volunteers
- 40,000 people, healthy volunteers welcome
- Sponsor
- Global Healthy Living Foundation