Clinical trials: Pancreatic Cyst
Pancreatic Cyst Fluid
Pancreatic Cyst Fluid Glucose: New Armamentarium in the Diagnosis of Mucinous Pancreatic Cystic Lesion
All participants undergoing radiological imaging and found to have pancreatic cyst of size > 2cm will be subjected to EUS (Endoscopic ultrasound) examination and cystic fluid will be aspirated for analysis, including cystic fluid…
- Trial name
- NCT05962723
- Testing
- EUS
- Volunteers
- 30 people
- Sponsor
- Asian Institute of Gastroenterology, India
Pancreatic Tumor, Benign, Pancreatic Neoplasms
Laser Tissue Welding - Distal Pancreatectomy Sealing Study
The laser tissue welding device is intended for use in patients requiring sealing of the pancreas after partial pancreatectomy, and including those patients who are fully heparinized or have hemodilutional coagulation failure.
- Conditions
- Pancreatic Tumor, Benign, Pancreatic Neoplasms, Pancreatic Adenocarcinoma, Pancreatic Pseudocyst
- Trial name
- LTW (NCT03147768)
- Testing
- Distal Pancreatectomy Sealing Using LTW
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Laser Tissue Welding, Inc.
Pancreatic Cyst
EUS-guided Through-the-needle Microforceps Biopsy Outcomes
INTRODUCTION: The diagnosis of pancreatic cystic lesions (PCLs) is increasing due to improvements of cross-sectional imaging. It is mandatory, for appropriate management, to make an accurate diagnosis and risk stratification…
- Trial name
- NCT04140435
- Testing
- EUS-guided through-the-needle microbiopsy forceps (Moray)
- Where
- Argentina
- Volunteers
- 50 people
- Sponsor
- Institute of Gastroenterology and Advance Endoscopy
Neoplasms, Cystic, Mucinous, and Serous, Pancreatic Neoplasms
Endoscopic Ethanol Ablation of Communicating Pancreatic Cystic Neoplasms
Pancreatic cysts are common, and some pancreas cysts have malignant potential. Usual treatment of these cysts is either observation or surgical removal of part or all of the pancreas.
- Conditions
- Neoplasms, Cystic, Mucinous, and Serous, Pancreatic Neoplasms, Ultrasonography, Interventional
- Trial name
- NCT01057355
- Testing
- EUS and/or ERCP with ethanol injections of pancreatic cyst
- Sponsor
- Mayo Clinic
Pancreatic Cyst
A Phase II Multicentre Trial of Endoscopic Ultrasound Guided Radiofrequency Ablation of Cystic Tumours of the Pancreas
Up to 13.5% of patients that undergo a magnetic resonance imaging (MRI) scan of their abdomen without pancreatic symptoms are found to have an incidental pancreatic cyst, with the frequency increasing with age.
- Trial name
- RADIOCYST01 (NCT02343692)
- Testing
- EUS guided RFA of cystic tumours of the pancreas
- Where
- 13 sites in Australia, United Kingdom
- Volunteers
- 97 people
- Sponsor
- University College, London
Pancreas Cancer, Pancreatitis
Pancreas Registry and High Risk Registry
The purpose of this study is to establish a registry of patients with pancreatic diseases. Patients included in the registry may include those with: pancreatic cancer, precancerous lesions of the pancreas, inflammatory lesions of…
- Conditions
- Pancreas Cancer, Pancreatitis, Chronic Pancreatitis, Pancreatic Cyst
- Trial name
- NCT02775461
- Where
- 2 sites in United States
- Volunteers
- 1,368 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Pancreas Cancer
International CAPS Registry: Pancreas Cancer Cases in Surveillance Programs
Various centers around the world are currently investigating the feasibility and yield of surveillance for pancreatic cancer in high-risk individuals.
- Trial name
- CAPS Registry (NCT02703545)
- Volunteers
- 58 people
- Sponsor
- Johns Hopkins University
Pancreatic Tumors
Evaluation of Image-guided Brushing of Pancreatic Cyst Wall in Diagnosis of Cystic Pancreatic Tumors
The goal of this study is to compare a sample of the cyst taken by a standard method (fine needle aspiration) to the sample taken by a new method using a device called the EchoBrush to see which method is more accurate at…
- Trial name
- NCT01455311
- Testing
- EUS Guided Fine Needle Aspiration, EUS Guided EchoBrush Sampling
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
IPMN, Pancreatic
Integration of Multiomics Markers for Invasive IPMNs Identification Through the Set-up of the INvasive Cyst bIomarkers Detection (INCITE) Consortium
Although intraductal papillary mucinous neoplasms (IPMNs) represent potential precursors of pancreatic cancer, IPMNs with invasive cancer are rare.
- Trial name
- INCITE (NCT06694792)
- Where
- Italy
- Volunteers
- 800 people
- Sponsor
- IRCCS San Raffaele
Pancreatic Steatosis, Pancreatic Cyst
Prevalence of Pancreatic Steatosis in Pancreatic Cystic Neoplasms and Pancreatic Adenocarcinoma
Several pancreatic neoplastic cystic lesions, such as IPMN (intrapapilary mucinous neoplasia), cystic neuroendocrine tumors (NET) and mucinous neoplasms, present a carcinogenetic risk, though it is yet unknown if this risk is…
- Conditions
- Pancreatic Steatosis, Pancreatic Cyst, Pancreatic Adenocarcinoma
- Trial name
- SPACE (NCT06867172)
- Testing
- computerized tomography, Endosonography (EUS)
- Where
- Romania
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Carol Davila University of Medicine and Pharmacy
Pancreatic Cyst
Study Using Hyperpolarized 13C-Pyruvate Magnetic Resonance Spectroscopic Imaging in Patients With Pancreatic Cysts Undergoing Surgical Resection
To learn if Hyperpolarized C-Pyruvate Magnetic Resonance (HP-MR) Spectroscopic Imaging can help doctors detect low-risk (benign) and high-risk (malignant) cysts.
- Trial name
- NCT05873699
- Testing
- Hyperpolarized 13-C-pyruvate
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- M.D. Anderson Cancer Center
Pancreatic Surgery, Pancreatic Duct Stenting
Pancreatic Stent to Prevent Leak After Distal Pancreatectomy
The purpose of this study is to investigate an intervention to prevent complications after pancreas surgery. The goal is to determine if placing a stent into the pancreatic duct before surgery will decrease or prevent leaking…
- Conditions
- Pancreatic Surgery, Pancreatic Duct Stenting, Pancreatic Cancer, Distal Pancreatectomy
- Trial name
- LEAPS (NCT00671463)
- Testing
- Pancreatic duct stenting
- Where
- United States
- Sponsor
- Massachusetts General Hospital
Appendicitis, Evidence of Cholecystectomy
Point of Care 3D Ultrasound for Various Applications: A Pilot Study
Summary 1. Purpose and Objective: The purpose of this study is to test the feasibility of rapid acquisition of point of care 3D ultrasound in obtaining abdominal and/or pelvic images.
- Conditions
- Appendicitis, Evidence of Cholecystectomy, Gallstones, Pregnancy, Ectopic
- Trial name
- NCT02831556
- Where
- United States
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Duke University
Pancreatic Cysts
International Registry for Intraductal Papillary Mucinous Neoplasma
A centralized web-based database will be used to track patients with IPMN lesions of the pancreas to study natural history and risk factors for malignant transformation in this multi-center study.
- Trial name
- NCT00828048
- Where
- United States
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Pancreatic Disease, Pancreatic Cancer
EUS Examination Using EndoSound Vision System vs. Standard Echoendoscope
This is a randomized trial to compare the standard echoendoscope with the newly developed EndoSound Visual System in the evaluation of lesions in the gastrointestinal tract.
- Conditions
- Pancreatic Disease, Pancreatic Cancer, Pancreatic Cyst, Gastrointestinal Tumor
- Trial name
- NCT06340620
- Testing
- Endoscopic ultrasound examination
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Orlando Health, Inc.
Pancreatic Cyst
Safety and Efficacy of EUS-RFA in the Treatment of Pancreatic Lesions: A Prospective Registry
Purpose: The purpose of this registry is to track the clinical outcomes and progression of patients with pancreatic lesions receiving endoscopic ultrasound (EUS)-based radiofrequency ablation (RFA) therapy.
- Trial name
- NCT07136324
- Testing
- EUS-guided RFA treatment
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- The University of Texas Health Science Center, Houston
Pancreatic Neoplasms, Pancreas Cyst
A Pan-European Study on Minimally Invasive Versus Open Pancreatoduodenectomy in High-volume Centers
RATIONALE: Minimally-invasive pancreatoduodenectomy (MIPD), either laparoscopic or robot-assisted, has been suggested as a valuable alternative to open pancreatoduodenectomy (OPD).
- Conditions
- Pancreatic Neoplasms, Pancreas Cyst, Pancreas Cancer
- Trial name
- MI-PD (NCT03172572)
- Testing
- Minimally invasive pancreatoduodenectomy, Open pancreatoduodenectomy
- Where
- Netherlands
- Volunteers
- 4,220 people
- Sponsor
- S (Sjors) Klompmaker, MD
Pancreatic Fluid Collections, Pancreatic Cyst
Registry of Pancreatic Fluid Collections and Pancreatic Cysts
This registry aims to assess the outcomes of patients undergoing EUS-guided interventions of pancreatic fluid collections and EUS examination of pancreatic cyst lesions.
- Trial name
- NCT02422095
- Testing
- Endoscopy-based (EUS-guided) interventions for pancreatic fluid collections, EUS of pancreatic cysts
- Where
- United States
- Sponsor
- AdventHealth
Pancreatic Cyst, Pancreatic Neoplasms
UCSF PANC Cyst Registry
Pancreatic cysts are found incidentally on 15-50% of CT and MRIs for all indications and their prevalence is increasing. Many of these cysts may be precursors to pancreatic cancer, and thus pose a substantial risk, however, the…
- Conditions
- Pancreatic Cyst, Pancreatic Neoplasms, Pancreatic Cancer, Pancreatic Diseases
- Trial name
- UCSF PCR (NCT04291651)
- Testing
- Survey
- Where
- United States
- Volunteers
- 4,000 people
- Sponsor
- University of California, San Francisco
Chronic Acute Pancreatitis
Evaluation of Pancreatic Duct Stenting in Patients With Pancreatic Pseudocysts.
The disruption of the pancreatic duct seems to be a major cause pseudocyst formation and persistence in patients suffering from acute/chronic pancreatitis.
- Trial name
- Disduct (NCT01276002)
- Testing
- pancreatic duct stenting
- Where
- Germany
- Sponsor
- University Hospital Schleswig-Holstein