Clinical trials: Pancreatic Fistula
PDAC of the Body and the Tail of the Pancreas, CR- POPF
Oncologic Impact of Pancreatic Fistula
Clinically-relevant post-operative fistula is a major complication after DP, but it did not affect post-operative therapeutic path nor oncologic long-term outcomes.
- Trial name
- POPF-DSS (NCT04348084)
- Where
- France
- Volunteers
- 382 people
- Sponsor
- University Hospital, Montpellier
Therapeutic Endoscopic Ultrasound, Advanced Endoscopy
Therapeutic Endoscopic Ultrasound for Gastrointestinal Disorders: A Multicenter Registry Study
The purpose of this retrospective chart-review registry study is to evaluate the safety profile, efficacy profile and cost-effectiveness of the various therapeutic endoscopic ultrasound (EUS) procedures (for benign and malignant…
- Conditions
- Therapeutic Endoscopic Ultrasound, Advanced Endoscopy, Therapeutic Endoscopy, Interventional Endoscopy
- Trial name
- TEUS Registry (NCT05051358)
- Testing
- Therapeutic Endoscopic Ultrasound
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- Advanced Endoscopy Research, Robert Wood Johnson Medical School Rutgers University
Pancreatic Fistula
Octreotide Microspheres for Preventing Pancreatic Fistula
This study is a randomized, double-blind, placebo-controlled, multicenter phase III clinical trial designed to evaluate the efficacy and safety of octreotide microspheres in preventing pancreatic fistula after distal…
- Trial name
- NCT07479784
- Testing
- Octreotide Microspheres
- Volunteers
- 230 people
- Sponsor
- Shanghai Zhongshan Hospital
Ampullary Cancer, Bile Duct Cancer
Modified vs Conventional Blumgart Anastomosis of LPD for the Effects of Pancreatic Fistula of Periampullary Carcinoma
The incidence rate and mortality rate of periampullary cancer at home and abroad both show an increasing trend, seriously affecting the health level of the people.
- Conditions
- Ampullary Cancer, Bile Duct Cancer, Pancreas Cancer, Duodenum Cancer
- Trial name
- NCT06076252
- Testing
- Modified Blumgart Anastomosis in LPD, conventional Blumgart anastomosis in LPD
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Affiliated Hospital of Guangdong Medical University
Anastomosis; Complications, Pancreatic Fistula
Pancreaticogastrostomy for High-Risk Pancreas
In 2013, a double purse-string telescoped pancreaticogastrostomy (PG) technique appeared to significantly reduce the risk of postoperative pancreatic fistula (POPF).
- Trial name
- GASTROPAN (NCT04724174)
- Testing
- pancreaticogastrostomy, pancreaticojejunostomy
- Volunteers
- 198 people
- Sponsor
- Institut Paoli-Calmettes
Anastomotic Leak, Fistula
Use of NERv's Inline Device as an Early Diagnostic Method for Postoperative Complications
NERv's traditional feasibility clinical trial is a multi-center, pre-market, single-arm, and non-randomized trial. This study will involve the retrospective analysis of prospectively collected data.
- Conditions
- Anastomotic Leak, Fistula, Postoperative Leak, Postoperative Pancreatic Fistula
- Trial name
- NCT04582708
- Testing
- NERv's Inline Device
- Where
- 7 sites in United States, Canada and 1 more
- Volunteers
- 316 people
- Sponsor
- FluidAI Medical
Pancreas Cancer, Fistula
Study Assessing the Effect of Transpapillary Pancreas Duct Stent in Resection of the Pancreatic Tail
Randomized study assessing the effect of transpapillary pancreas duct stent in resection of the pancreatic tail.
- Trial name
- NCT00500968
- Testing
- stent, Distal pancreatectomy
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Karolinska Institutet
Pancreaticoduodenal; Fistula
Modified Reconstruction for Pancreatic Head Resection
This observational study aims to prove the safety and efficacy of a modified method of reconstruction after pancreatic head resection utilizing a single Omega shaped intestinal Loop with an additional anastomosis between the…
- Trial name
- NCT03277625
- Testing
- modified omega-shaped single-loop
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- St. Josef Hospital Bochum
Pancreatic Fistula
Role of Preoperative Multislice Computed Tomography in Whipple's Operation.
Preoperative assessment of visceral fat volume(VFV),total fat volume(TFV),pancreas/spleen density ratio and pancreatic duct diameter by multislice computed tomography abdomen to predict the risk of pancreatic fistula after…
- Trial name
- NCT04582461
- Testing
- multislice computed tomography
- Volunteers
- 100 people
- Sponsor
- Assiut University
Pancreatic Cancer, Pancreatic Fistula
Laparoscopic Pancreaticoduodenectomy
Laparoscopic pancreaticoduodenectomy was first performed by Garner and Pomp in 1994. This is a technically difficult, time consuming and high rate of complication procedure.
- Conditions
- Pancreatic Cancer, Pancreatic Fistula, Periampullary Cancer
- Trial name
- LPD (NCT07009119)
- Testing
- laparoscopic Pancreaticoduodenectomy
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Minia University
Periampullary Neoplasms, Pancreatic Cancer
Total Pancreatectomy With Islet Autotransplantation (TPIAT) for High-Risk Patients With Pancreatic Tumors
This is a single-center, prospective, single-arm feasibility study evaluating whether adult patients with periampullary neoplasms who are at high risk for postoperative pancreatic fistula after pancreaticoduodenectomy can be…
- Conditions
- Periampullary Neoplasms, Pancreatic Cancer, Pancreatic Neoplasms
- Trial name
- NCT07360119
- Testing
- Total Pancreatectomy with Islet Autotransplantation (TPIAT)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Pancreatic Fistula
Somatostatin Prevent Post-operation Pancreatic Fistula in Intermediate Risk Patients After Pancreaticoduodenectomy
This study is designed to assess the preventive effects of somatostatin on post-operation pancreatic fistula in intermediate risk patients after pancreaticoduodenectomy.
- Trial name
- NCT03349424
- Testing
- Somatostatin
- Where
- China
- Volunteers
- 205 people
- Sponsor
- Peking Union Medical College Hospital
Disease of Pancreatic or Periampullary Lesions
PoLyglycolic Acid Felt reiNforcEmenT of the PancreaticoJejunostomy (PLANET-PJ Trial)
The polyglycolic acid (PGA) felt is a felt-like absorbable suture reinforcing material. The pancreatojejunostomy aimed at reducing POPF is not established at present. We devised a new method using doubly PGA felt.
- Trial name
- NCT03331718
- Testing
- PGA felt reinforcement
- Where
- Japan
- Volunteers
- 514 people
- Sponsor
- University of Toyama
Pancreaticoduodenectomy
Isolated Pancreatic Loop With Modified Pancreaticojejunostomy
The aim of the present study was to observe whether the modified pancreatico- jejunostomy (PJ ) technique with an isolated pancreatic loop would effectively reduce the POPF rate and overall morbidity after PD
- Trial name
- NCT04843670
- Testing
- duodenopancreatectomy
- Volunteers
- 201 people
- Sponsor
- Université de Sousse
Pancreatic Carcinoma, Pancreatic Neoplasm
Lanreotide Versus Placebo Before Surgery to Prevent a Surgical Complication Called a Pancreatic Fistula
This phase III trial compares the effect of using lanreotide before surgery to surgery alone in preventing pancreatic fistulas in patients with pancreatic cancer or a pancreatic lesion that could become cancerous.
- Trial name
- NCT06807437
- Testing
- Biospecimen Collection, Distal Pancreatectomy, Lanreotide
- Where
- 118 sites in United States
- Volunteers
- 274 people
- Sponsor
- SWOG Cancer Research Network
Pancreatic Fistula, Pancreatic Neoplasms
Greater Omentum Binding to the Pancreatic Stump to Prevent Pancreatic Fistula Following Distal Pancreatectomy
Background and aim: Distal pancreatectomy (DP) is often performed for primary benign or malignant lesions occurred in the body or tail of the pancreas.
- Trial name
- NCT03752086
- Testing
- greater omentum binding, Pancreatic stump exposed without omentum binding
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Tongji Hospital
Pancreas Cancer, Pancreatic Fistula
Validations of New cut-of for the Stratification of Postoperative Complications,Drains Management
Pancreatic fistula (PF) represents the Achille's heel of pancreatic surgery and is the main cause of postoperative morbidity since it can determine the onset of others complications such as abdominal abscesses, surgical wound…
- Trial name
- DALCUT (NCT04380506)
- Testing
- Surgical Drains Management
- Where
- Italy
- Volunteers
- 165 people
- Sponsor
- Campus Bio-Medico University