Clinical trials: Pancreatic Tumor
Pancreatic Cancer
Capecitabine/Erlotinib Followed of Gemcitabine Versus Gemcitabine/Erlotinib Followed of Capecitabine
This crossover trial is performed in advanced and metastatic pancreatic cancer not previously exposed to chemotherapy. The study compares a standard arm with gemcitabine plus erlotinib to an experimental arm with capecitabine…
- Trial name
- NCT00440167
- Testing
- Gemcitabine, Capecitabine, Erlotinib
- Volunteers
- 280 people
- Sponsor
- PD Dr. med. Volker Heinemann
Pancreatic Cancer, EUS-FNB
Profiling the Intratumoral Microbiome of Pancreatic Ductal Adenocarcinoma Based on EUS-FNB Tissue Samples and Exploring Its Impact on Tumor Diagnosis and Prognosis.
The goal of this observational study is to use endoscopic ultrasound-guided fine-needle biopsy (EUS-FNB) to investigate the intratumoral microbiome profile in patients with pancreatic ductal adenocarcinoma (PDAC) and to evaluate…
- Conditions
- Pancreatic Cancer, EUS-FNB, Intratumoral Microbiota, Diagnosis
- Trial name
- NCT06655233
- Where
- China
- Volunteers
- 50 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Pancreas Cancer, Chemotherapy
The Survival Outcome of Adjuvant Chemotherapy for Stage I Pancreatic Cancer
This study aimed to evaluate the impact of adjuvant chemotherapy on survival in patients with Stage I pancreatic cancer stratified by pathologic risk factors.
- Trial name
- NCT06208436
- Testing
- Adjuvant chemotherapy
- Where
- China
- Volunteers
- 250 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Pancreatic Cancer, Surgery
Reconstruction Method and Delayed Gastric Emptying After Pancreatic Surgery
Pancreaticoduodenectomy (whipple procedure) is the standard operation for tumors of the pancreatic head, uncinate process, distal common bile duct as well as the papilla of vater.
- Conditions
- Pancreatic Cancer, Surgery, Improvement of Perioperative Outcome
- Trial name
- NCT01248663
- Testing
- antecolic reconstruction, retrocolic reconstruction
- Where
- Austria
- Volunteers
- 64 people
- Sponsor
- Medical University of Vienna
Tumor of Exocrine Pancreas
Distal Pancreatectomy With Partial Splenectomy for Pancreatic Tumors
Most resectable tumors arising in the body or tail of the pancreas are malignancies or premalignancies which are surgically treated with distal pancreatectomy in combination with splenectomy.
- Trial name
- NCT01412684
- Testing
- Distal pancreatectomy with partial splenectomy
- Where
- United States
- Sponsor
- University of Missouri-Columbia
Pancreatic Cancer, Esophageal Cancer
Perioperative Geriatrics Intervention for Older Cancer Patients Undergoing Surgical Resection
The purpose of this research study is to addresses the challenge of managing the unique perioperative needs of older cancer patients undergoing surgical resection.
- Conditions
- Pancreatic Cancer, Esophageal Cancer, Gastric Cancer, Rectal Cancer
- Trial name
- NCT02810652
- Testing
- Usual Care, Perioperative Geriatrics Intervention
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Massachusetts General Hospital
Pancreatic Cancer, Lung Cancer, Nonsmall Cell
Study of PRO in Patients With Advanced Pancreatic or Biliary Tract Cancer (BetterEveryDay)
Pancreatic and biliary tract cancer are ones of the leading causes of cancer-related deaths. During the course of illness, these patients often experience marked physical suffering, psychological distress and frequent unplanned…
- Trial name
- BetterEveryDay (NCT04611867)
- Testing
- Supportive application with integrated weekly PRO
- Where
- Denmark
- Volunteers
- 274 people
- Sponsor
- Inna Chen, MD
Breast Cancer, Lung Cancer
IDO Inhibitor Study for Relapsed or Refractory Solid Tumors
This study provides an early evaluation of an entirely new class of small molecule agents directed at disruption or elimination of tumor tolerance, a phenomenon now demonstrated to be involved in the growth of many solid tumors.
- Conditions
- Breast Cancer, Lung Cancer, Melanoma, Pancreatic Cancer
- Trial name
- D-1MT (NCT00739609)
- Testing
- 1-methyl-D-tryptophan
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- NewLink Genetics Corporation
Rheumatoid Arthritis, Ankylosing Spondylitis
PatientSpot Formerly Known as ArthritisPower
Patient Power is a patient research network and database (registry) to collect prospective information about demographics, self-reported diagnoses and medications, and willingness to participate in research from participants with…
- Conditions
- Rheumatoid Arthritis, Ankylosing Spondylitis, Fibromyalgia, Gout
- Trial name
- NCT03840928
- Where
- United States
- Volunteers
- 40,000 people, healthy volunteers welcome
- Sponsor
- Global Healthy Living Foundation
Pancreatic Cancer
Safety and Efficacy Study of Different Doses of 90Y-hPAM4 Combined With Gemcitabine in Pancreatic Cancer
This is a study to test whether different doses of 90Y-hPAM4 are safe to give in combination with gemcitabine in patients with previously untreated pancreatic cancer.
- Trial name
- NCT00603863
- Testing
- IMMU-107 (hPAM4)
- Where
- 11 sites in United States
- Volunteers
- 80 people
- Sponsor
- Gilead Sciences
Pancreatic Pseudocyst
Laparoscopic Cystogastrostomy Versus Endoscopic Cystogastrostomy
This study is a randomized controlled trial comparing Laparoscopic and endoscopic drainage for pseudocyst of the pancreas secondary to acute pancreatitis.
- Trial name
- NCT02041793
- Testing
- Laparoscopic cystogastrostomy, Endoscopic cystogastrostomy
- Where
- India
- Volunteers
- 60 people
- Sponsor
- All India Institute of Medical Sciences
Ovarian Neoplasms, Colorectal Neoplasms
An Analysis of the Response of Human Tumor Microvascular Endothelium to Ionizing Radiation
Doctors will take some tissue from the tissue removed during surgery in order to study how the blood vessels of the tumor respond to radiation therapy.
- Conditions
- Ovarian Neoplasms, Colorectal Neoplasms, Melanoma, Small Cell Lung Cancer
- Trial name
- NCT00132704
- Testing
- Ionizing radiation (IR) therapy, Ionizing radiation (IR)
- Where
- United States
- Volunteers
- 149 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Ovarian Neoplasms, Endometrial Neoplasms
A Study of Sofe-M in Participants With Selected Advanced Solid Tumors
The purpose of this study is to find out whether the study drug, Sofetabart Mipitecan (LY4170156), is safe, tolerable and effective in participants with advanced solid tumors.
- Conditions
- Ovarian Neoplasms, Endometrial Neoplasms, Uterine Cervical Neoplasms, Carcinoma, Non-Small-Cell Lung
- Trial name
- NCT06400472
- Testing
- Sofe-M, bevacizumab, carboplatin
- Where
- 25 sites in United States, Australia and 5 more
- Volunteers
- 575 people
- Sponsor
- Eli Lilly and Company
Solid Tumor, Microsatellite Instability-High (MSI-H) Solid Tumors
A Study of Anti-PD-L1 Checkpoint Antibody (LY3300054) Alone and in Combination in Participants With Advanced Refractory Solid Tumors
The main purpose of this study is to evaluate the safety and tolerability of anti-programmed cell death ligand 1 (PD-L1) checkpoint antibody LY3300054 in participants with advanced refractory solid tumors.
- Conditions
- Solid Tumor, Microsatellite Instability-High (MSI-H) Solid Tumors, Cutaneous Melanoma, Pancreatic Cancer
- Trial name
- PACT (NCT02791334)
- Testing
- LY3300054, Ramucirumab, Abemaciclib
- Where
- 14 sites in United States, Belgium and 5 more
- Volunteers
- 164 people
- Sponsor
- Eli Lilly and Company
Exocrine Pancreatic Insufficiency (EPI)
Study Of Effects Of Oral CREON Capsules In Adult Participants With Exocrine Pancreatic Insufficiency Not Due To Cystic Fibrosis, Chronic Pancreatitis, Pancreatectomy, Or Pancreatic Cancer
Exocrine pancreatic insufficiency (EPI) is a condition where the pancreas does not have enough pancreatic enzymes to break down food.
- Trial name
- NCT04315311
- Testing
- CREON
- Sponsor
- AbbVie
Pancreatic Cancer, Pancreatic Cancer Non-resectable
RP72 Monotherapy and in Combination With Gemcitabine in Patients With Pancreatic Cancer
This is a Phase I, multi center study to evaluate the safety and efficacy and determine the maximum tolerated dose (MTD) of RP72 as monotherapy and RP72 in combination with Gemcitabine in patients with pancreatic cancer.
- Conditions
- Pancreatic Cancer, Pancreatic Cancer Non-resectable, Pancreatic Cancer Metastatic
- Trial name
- NCT04338763
- Testing
- RP72, Gemcitabine
- Where
- 2 sites in Taiwan
- Volunteers
- 48 people
- Sponsor
- Rise Biopharmaceuticals, Inc.
Familial Pancreatic Cancer, Familial Pancreatic Carcinoma
A Liquid Biopsy for Pancreatic Cancer Early-detection and Disease Monitoring
Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal malignancy characterized by an asymptomatic early phase, late diagnosis, and poor survival, particularly in individuals who develop disease outside the context of…
- Conditions
- Familial Pancreatic Cancer, Familial Pancreatic Carcinoma, Hereditary Pancreatic Cancer, Hereditary Pancreatitis
- Trial name
- PANXEON (NCT07700992)
- Testing
- PANXEON
- Where
- Italy
- Volunteers
- 600 people
- Sponsor
- Università Vita-Salute San Raffaele
Pancreas Cancer
Development of a Prediction Platform for Neoadjuvant Treatment and Prognosis in Pancreatic Cancer Using Organoid
The investigators create organoid from the pancreatic cancer tissue obtained via EUS-FNA and EUS-FNB within the pancreatic cancer diagnostic process.
- Trial name
- NCT04777604
- Testing
- Organoid
- Where
- South Korea
- Volunteers
- 300 people
- Sponsor
- Samsung Medical Center
Metastatic Pancreatic Cancer, Unresectable Pancreatic Cancer
EL CENTRO: Engaging Latinos in the Center of Cancer Treatment Options
The objective of this study is to improve the chemotherapy decision making process for Latinos with advanced gastrointestinal cancers.
- Conditions
- Metastatic Pancreatic Cancer, Unresectable Pancreatic Cancer, Metastatic Colorectal Cancer
- Trial name
- NCT03602885
- Testing
- Usual chemotherapy education (CE), Chemotherapy education intervention (CEI)
- Where
- 5 sites in United States
- Volunteers
- 10 people
- Sponsor
- Dana-Farber Cancer Institute
Cancer of Pancreas, Cancer of Duodenum
Enteral Nutrition After Pancreaticoduodenectomy
Pancreaticoduodenectomy (PD) is the treatment of choice for resectable periampullary cancer. PD is still associated with a relatively a high incidence of delayed gastric emptying.
- Conditions
- Cancer of Pancreas, Cancer of Duodenum, Ampulla of Vater Cancer, Cholangiocarcinoma
- Trial name
- NCT03150615
- Testing
- Early enteral nutrition, Saline, nasojejunal tube insertion
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Nanjing Medical University
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