Clinical trials: Pancreaticoduodenectomy
Pancreatectomy; Hyperglycemia, Diabete Mellitus
Glucose Metabolism After Partial Pancreatectomy
This is a single center observational study to assess alteration of glucose metabolism after pancreatectomy.
- Trial name
- NCT04409171
- Testing
- oral glucose tolerance test
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Pancreatoduodenectomy, PPPD
Duration of Perioperative Antibiotics in Pancreatoduodenectomy
The goal of this clinical trial is to compare two perioperative antibiotic prophylaxis regimens in adult patients undergoing pancreatoduodenectomy (PD) or pylorus-preserving pancreatoduodenectomy (PPPD).
- Conditions
- Pancreatoduodenectomy, PPPD, Infectious Complications
- Trial name
- NCT07043855
- Testing
- single dose preoperative antibiotic, Prolonged perioperative antibiotics
- Where
- South Korea
- Volunteers
- 558 people
- Sponsor
- Asan Medical Center
Pancreatic Fistula
External Pancreatic Duct Stent After Pancreaticoduodenectomy
Pancreatoduodenectomy (PD) is performed in many high volume centers with a very low mortality. Reduced mortality rate is largely the result of careful patient selection, improved intraoperative management and a better…
- Trial name
- NCT01068886
- Testing
- External pancreatic stent
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Angers
Obstructive Jaundice, Pancreatic Head Cancer
Impact of Intraoperative PTCD Catheter Retention Versus Removal on Postoperative Short-term Outcomes After Pancreaticoduodenectomy in Obstructive Jaundice
Pancreaticoduodenectomy (PD) is a complex surgical procedure commonly performed for tumors of the pancreatic head and periampullary region.
- Conditions
- Obstructive Jaundice, Pancreatic Head Cancer, Periampullary Neoplasms, Biliary Tract Neoplasms
- Trial name
- NCT07532759
- Testing
- PTCD Catheter Removal, PTCD Catheter Retention
- Volunteers
- 100 people
- Sponsor
- Xu'an Wang
Pancreatic Fistula
Comparison of Feasibility Between Internal and External Pancreatic Drainage in Pancreaticoduodenectomy
Pancreatic fistula is one of the most serious complication after pancreatoduodenectomy. To reduce pancreatic fistula, many authors recommend pancreatic stent in pancreatojejunostomy.
- Trial name
- NCT01023594
- Testing
- Pancreatic stent
- Where
- 8 sites in South Korea
- Volunteers
- 328 people
- Sponsor
- Seoul National University Hospital
Pancreas Head Cancer, Pancreas Adenocarcinoma
Preventing Postoperative Complications in Patients Undergoing High-risk Pancreatoduodenectomy With a Bundle Approach Including Hydrocortisone, Octreotide, and the Teres Ligament Patch (PANENCA)
The PANENCA trial aims to reduce postoperative complications in patients undergoing pancreatoduodenectomy (also known as a Whipple procedure), a complex surgical operation performed to remove tumors located in or near the head of…
- Conditions
- Pancreas Head Cancer, Pancreas Adenocarcinoma, IPMN, Pancreatic, Cholangio Carcinoma
- Trial name
- PANENCA (NCT07262957)
- Testing
- HOP bundle
- Where
- Netherlands
- Volunteers
- 400 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Pancreas Neoplasm
Postoperative Outcomes After Partial Duodenopancreatectomy Versus Total Pancreatectomy
The goal of this observational study is to compare short-term outcomes after partial pancreatoduodenectomy and total pancreatectomy in adults undergoing elective surgery for pancreatic or periampullary neoplasms in Switzerland.
- Trial name
- NCT07831694
- Volunteers
- 3,602 people
- Sponsor
- Cantonal Hospital of St. Gallen
Pancreaticoduodenectomy, Postoperative Pancreatic Fistula
Saleh's Technique for Pancreaticojejunostomy (Pancreatic Parenchymal Injection of N-butyl-2-cyanoacrylate)
This study investigates the safety and efficacy of injecting N-butyl-2-cyanoacrylate (Histoacryl®) into the pancreatic parenchyma during pancreaticoduodenectomy (PD) to enhance the security of the pancreaticojejunostomy (PJ)…
- Conditions
- Pancreaticoduodenectomy, Postoperative Pancreatic Fistula, Pancreas Cancer, Periampullary Cancer
- Trial name
- NBCA (NCT07132541)
- Testing
- Pancreatic parenchymal injection of N-butyl-2-cyanoacrylate(Histoacryl®)
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Minia University
Enteral Nutrition
Comparing Early Enteral Nutrition Versus Parenteral Nutrition After Pancreaticoduodenectomy
To prove that early enteral nutrition after pancreaticoduodenal operation is of great significance to improve the immune response, reduce the incidence of postoperative infection and other related complications, and shorten the…
- Trial name
- NCT04704895
- Testing
- Total parenteral nutrition, Enteral nutrition
- Where
- China
- Volunteers
- 210 people
- Sponsor
- Xian-Jun Yu
Surgical Wound Infection, Pancreatic Neoplasms
The Use of Wound Protector in Whipple's Procedure With Intrabiliary Stent
Background: There are no published studies regarding the use of wound protectors in the context of surgical site infection (SSI) rates among patients receiving a pancreatoduodenectomy (Whipple) with preoperatively placed…
- Trial name
- NCT01836237
- Testing
- Alexis - a wound protector
- Where
- Canada
- Volunteers
- 107 people
- Sponsor
- University of Calgary
Patients Who Undergo Pancreaticoduodenectomy
Safety and Efficacy of Anricfen for Postoperative Analgesia and Rehabilitation Promotion After Pancreaticoduodenectomy.Intervention Measures: For Normal Adults, Administer Ariceptin Injection Intravenously Post-operation at a Dose of 1 μg/Kgevery 8 Hours for Three Consecutive Days After Surgery.
Exploring the effectiveness and safety of early use of Ariceptinfen after pancreaticoduodenectomy in alleviating postoperative pain and promoting recovery of patients.
- Trial name
- NCT07514637
- Testing
- Experimental Group, Anrikefon
- Where
- China
- Volunteers
- 35 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Pancreaticoduodenectomy, Postoperative Pancreatic Fistula
Different Pancreaticojejunostomy After Pancreaticoduodenectomy
The aim of this study was to reduce the incidence of postoperative pancreatic fistula after pancreaticoduodenectomy by using different pancreaticojejunostomy methods according to the position of the pancreatic duct.
- Trial name
- NCT05475275
- Testing
- pancreaticojejunostomy
- Where
- China
- Volunteers
- 924 people
- Sponsor
- Junjie Xiong
Pancreatic Fistula
One-layer Versus Two-layer Duct-to-mucosa Pancreaticojejunostomy After Pancreaticoduodenectomy
The aim of this study is to investigate a new pancreaticojejunal (PJ) anastomosis procedure named "One-layer duct-to-mucosa pancreaticojejunostomy" in pancreatoduodenectomy, which could provide a feasible option to pancreatic…
- Trial name
- NCT02511951
- Testing
- pancreaticojejunostomy
- Where
- China
- Volunteers
- 114 people
- Sponsor
- The Second Hospital of Anhui Medical University
Pancreatic Carcinoma, Cholangiocarcinoma
In This Study, a Retrospective Analysis Was Conducted to Explore the Risk Factors for Patients Undergoing Pancreaticoduodenal Surgery (PD) to Achieve TO, and a Nomogram Prediction Model Was Further Established to Promote the Standardization and Standardization of PD Surgical Quality Evaluation.
This study is committed TO exploring the risk factors affecting patients receiving pancreaticoduodenal surgery (PD) to achieve TO by retrospective analysis of clinical data of patients receiving PD surgery in Changzhou Second…
- Conditions
- Pancreatic Carcinoma, Cholangiocarcinoma, Pancreaticoduodenectomy
- Trial name
- NCT06763250
- Where
- China
- Volunteers
- 280 people
- Sponsor
- luokai zhang
Pancreaticoduodenectomy, Distal Pancreatectomy
The Novel Modified Cattell-Warren Duct-To-Mucosa Pancreaticojejunostomy Technique Significantly Reduces POPF.
Pancreatic surgeries, such as pancreaticoduodenectomy and distal pancreatectomy, are associated with high morbidity and mortality. The most common cause of this morbidity is postoperative pancreatic fistula(POPF).
- Conditions
- Pancreaticoduodenectomy, Distal Pancreatectomy, Postoperative Pancreatic Fistula
- Trial name
- POPF (NCT07038161)
- Testing
- Modified Cattell-Warren duct-to-mucosa pancreaticojejunostomy, Institutional Prehabilitation Protocol
- Where
- Nepal
- Volunteers
- 27 people
- Sponsor
- Nepal Medical College and Teaching Hospital
Pancreatic Cancer, Pancreatic Surgery
Effect of Surgeon Volume on Outcome of Pancreaticoduodenectomy
The independent impact of surgeon volume on outcome of patients undergoing pancreaticoduodenectomy in a high-volume Institution was assessed.
- Trial name
- NCT01059097
- Testing
- Pancreaticoduodenectomy
- Where
- Italy
- Volunteers
- 610 people
- Sponsor
- Università Vita-Salute San Raffaele
Pancreatic Cancer, Periampullary Cancer
Tissue Adhesive Glue Modified Cyanoacrylate (Glubran® 2) in Soft Pancreas
This is a single-center, randomized controlled trial comparing the efficacy of pancreaticojejunostomy with modified N-butyl-2-cyanoacrylate(Glubran® 2) versus standard pancreaticojejunostomy without cyanoacrylate in preventing…
- Conditions
- Pancreatic Cancer, Periampullary Cancer, Duodenal Cancer, Cholangiocarcinoma
- Trial name
- NBCA-MS (NCT07155525)
- Testing
- Pancreaticojejunostomy with Modified N-Butyl-2-Cyanoacrylate (Glubran® 2), Standard(duct-to-mucosa) Pancreaticojejunostomy
- Where
- Egypt
- Volunteers
- 194 people
- Sponsor
- Minia University
Pancreaticoduodenectomy
Effects of Immunonutrition in Patients Undergoing Pancreaticoduodenectomy
The purpose of this study is to determine whether immunonutrition is effective on surgical site infection and Th1/Th2/Th17 differentiation in patients undergoing pancreaticoduodenectomy
- Trial name
- NCT00668876
- Testing
- Oral IMPACT, Parenteral nutrition
- Where
- Japan
- Volunteers
- 30 people
- Sponsor
- Chiba University
Pancreas Cancer
Preoperative Stent Study
Randomized study comparing the effect of plastic stents to that of expandable metal stents as pre-operative drainage of the bile ducts prior to Whipple operation.
- Trial name
- NCT00501176
- Testing
- Plastic and metalic stent inserion
- Where
- Sweden
- Volunteers
- 92 people
- Sponsor
- Karolinska Institutet
Pancreatic Cancer
Randomized Trial of Restrictive Versus Liberal Perioperative Fluid Management for Patients Undergoing Pancreatic Resection
The purpose of this study is to help us learn what the best amount of fluid is that patients should receive during pancreas surgery.
- Trial name
- NCT01058746
- Testing
- restrictive perioperative fluid management, Liberal perioperative fluid management
- Where
- United States
- Volunteers
- 331 people
- Sponsor
- Memorial Sloan Kettering Cancer Center