Clinical trials: Pancreaticoduodenectomy, active
Pancreaticoduodenectomy
Postoperative Pancreatic Fistula Following Pancreaticoduodenectomy
Postoperative pancreatic fistula (POPF) especially clinically relevant POPF (CR-POPF; Grades B and C) is one of the critical and challenging post pancreaticoduodenectomy complications.
- Trial name
- NCT07854353
- Testing
- pancreaticoduodenectomy
- Volunteers
- 200 people
- Sponsor
- Assiut University
Pancreaticoduodenectomy, Postoperative Pancreatic Fistula
Saleh's Technique for Pancreaticojejunostomy (Pancreatic Parenchymal Injection of N-butyl-2-cyanoacrylate)
This study investigates the safety and efficacy of injecting N-butyl-2-cyanoacrylate (Histoacryl®) into the pancreatic parenchyma during pancreaticoduodenectomy (PD) to enhance the security of the pancreaticojejunostomy (PJ)…
- Conditions
- Pancreaticoduodenectomy, Postoperative Pancreatic Fistula, Pancreas Cancer, Periampullary Cancer
- Trial name
- NBCA (NCT07132541)
- Testing
- Pancreatic parenchymal injection of N-butyl-2-cyanoacrylate(Histoacryl®)
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Minia University
Whipple Procedures, Pancreatic Cancer
Energy Expenditure and Nutrition After Pancreatic Surgery
This prospective observational cohort study examines the energy requirements and nutritional care of patients undergoing total or partial pancreatectomy for pancreatic tumors.
- Conditions
- Whipple Procedures, Pancreatic Cancer, Pancreaticoduodenectomy, Pancreatic Neoplasms
- Trial name
- NUTRI-PD (NCT07703813)
- Testing
- Pancreatectomy, Indirect calorimetry
- Where
- Greece
- Volunteers
- 150 people
- Sponsor
- Evangelismos Hospital
Pancreaticoduodenectomy, Antibiotherapy
Postoperative Anti-infective Strategy Following Pancreaticoduodenectomy in Patients With Preoperative Biliary Stent
The main objective of the study is to compare 2 broad-spectrum antibiotic (Piperacillin / Tazobactam) treatment modalities, following pancreaticoduodenectomy in patients with preoperative biliary stent, to demonstrate the…
- Trial name
- FRENCH24 ANIS (NCT06123169)
- Testing
- Antibioprophylaxis (Piperacillin-tazobactam), 5 days Antibiotherapy (Piperacillin-tazobactam)
- Where
- France
- Volunteers
- 326 people
- Sponsor
- University Hospital, Rouen
Patients Who Undergo Pancreaticoduodenectomy
Safety and Efficacy of Anricfen for Postoperative Analgesia and Rehabilitation Promotion After Pancreaticoduodenectomy.Intervention Measures: For Normal Adults, Administer Ariceptin Injection Intravenously Post-operation at a Dose of 1 μg/Kgevery 8 Hours for Three Consecutive Days After Surgery.
Exploring the effectiveness and safety of early use of Ariceptinfen after pancreaticoduodenectomy in alleviating postoperative pain and promoting recovery of patients.
- Trial name
- NCT07514637
- Testing
- Experimental Group, Anrikefon
- Where
- China
- Volunteers
- 35 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Pancreaticoduodenectomy, Nasogastric Tube Decompression
Omitting Nasogastric Tube Decompression in Minimally Invasive Pancreaticoduodenectomy
This study will evaluate two perioperative nasogastric tube strategies in patients undergoing laparoscopic pancreatoduodenectomy.
- Conditions
- Pancreaticoduodenectomy, Nasogastric Tube Decompression, Minimally Invasive Surgical Procedures
- Trial name
- NCT07370116
- Testing
- nasogastric tube decompression, Omission of nasogastric tube decompression
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Morbidity, Celiac Axis Stenosis
The Effect of Celiac Axis Stenosis on Morbidity After Pancreatoduodenectomy - A Prospective Study
The association between celiac axis stenosis and morbidity after pancreaticoduodenectomy is the primary focus of the study.
- Conditions
- Morbidity, Celiac Axis Stenosis, Pancreaticoduodenectomy, Pancreatic Cancer
- Trial name
- NCT07412301
- Where
- Greece
- Volunteers
- 99 people
- Sponsor
- Larissa University Hospital
Pancreatic Fistula, Pancreaticoduodenectomy
Prevention of Postoperative Pancreatic Fistula Following Pancreaticoduodenectomy by Preoperative Radiotherapy : a Phase 2 Trial
Design of the study Prospective, single arm, multicentric, phase II open trial Number of participating sites 14 French centers of HPB Surgery departments associated with 14 Radiation Oncology Departments.
- Trial name
- PreFiR (NCT07370987)
- Testing
- Stereotactic radiotherapy / pancreaticoduodenectomy
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pancreaticoduodenectomy, Postoperative Pancreatic Fistula
Pancreatic Parenchymal Injection of N-butyl-2-cyanoacrylate
This randomized controlled trial investigates the safety and efficacy of injecting N-butyl-2- cyanoacrylate (Histoacryl®) into the pancreatic parenchyma during pancreaticoduodenectomy (PD) to enhance the security of the…
- Conditions
- Pancreaticoduodenectomy, Postoperative Pancreatic Fistula, Pancreas Cancer, Periampullary Cancer
- Trial name
- NBCA (NCT07230509)
- Testing
- Pancreatic parenchymal injection of N-butyl-2- cyanoacrylate(Histoacryl®)Injection Group., Standard Pancreaticojejunostomy
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Minia University
Pancreaticoduodenectomy, ERAS
ERAS Program Implementation for MIPD
To evaluate the impact of an Enhanced Recovery After Surgery (ERAS) program on postoperative recovery in patients undergoing minimally invasive pancreatoduodenectomy (MIPD)
- Conditions
- Pancreaticoduodenectomy, ERAS, Minimally Invasive Surgery
- Trial name
- NCT07017361
- Testing
- Conventional, ERAS
- Where
- South Korea
- Volunteers
- 140 people
- Sponsor
- Seoul National University Hospital
Pancreaticoduodenectomy
Impact of External Drainage of the Main Pancreatic Duct and Common Bile Duct on Pancreatic Fistula Following Pancreaticoduodenectomy
Pancreaticoduodenectomy (PD) is the standard treatment for tumors of the pancreatic head, distal bile duct, duodenum, and ampulla of Vater.
- Trial name
- NCT06322680
- Testing
- Main pancreatic duct and biliary duct external drainage, Main pancreatic duct and biliary duct internal drainage
- Where
- China
- Volunteers
- 322 people
- Sponsor
- Shanghai Zhongshan Hospital
Intra Abdominal Pressure, Abdominal Compartment Syndrome
Intra-abdominal Hypertension and Abdominal Compartment Syndrome in Patients After Pancreatic Procedures.
This study investigates the development of intra-abdominal hypertension and compartment syndrome in patients undergoing elective pancreatic procedures.
- Conditions
- Intra Abdominal Pressure, Abdominal Compartment Syndrome, Pancreatic Surgery, Pancreatic Fistula After Pancreaticoduodenectomy
- Trial name
- HYPA (NCT06672601)
- Where
- Czechia
- Volunteers
- 150 people
- Sponsor
- Charles University, Czech Republic
Pancreatic Carcinoma, Laparoscopic
Comparing Laparoscopic and Open Surgery for Pancreatic Carcinoma
Background: Pancreatic cancer (PC) is one of the most aggressive malignant neoplasms with poor outcomes. Pancreatoduodenectomy (PD) is the only curative treatment for PC.
- Conditions
- Pancreatic Carcinoma, Laparoscopic, Pancreaticoduodenectomy
- Trial name
- NCT03785743
- Testing
- TLPD Surgery, OPD Surgery
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Tongji Hospital