Clinical trials: Pancreatitis, Chronic
Pancreatitis
Comparison of ESWL Alone and ESWL + Endoscopy for Painful Chronic Pancreatitis
Endoscopy is an established method of treatment for painful obstructive calcified pancreatitis. It involves the disintegration of calcifications using extracorporeal shock wave lithotripsy (ESWL) followed by endoscopic removal of…
- Trial name
- NCT00133835
- Testing
- Extracorporeal shock wave lithotripsy, Endoscopic drainage of the main pancreatic duct
- Where
- 2 sites in Belgium, Italy
- Volunteers
- 50 people
- Sponsor
- Erasme University Hospital
Biliary Stricture, Chronic Pancreatitis
Endoscopic Treatment of Biliary Stricture Caused by Chronic Pancreatitis
Benign biliary strictures can be endoscopically treated with plastic or self-expandable metal stents (SEMS). The purpose of the prospective randomized study is to compare the safety and feasibility of covered SEMS with multiple…
- Trial name
- NCT01085747
- Where
- Finland
- Volunteers
- 60 people
- Sponsor
- Helsinki University Central Hospital
Chronic Pancreatitis
Analysis of Graft Function Following Autologous Islet Transplantation
Analyze inflammatory markers and islet graft function through blood samples collected from subjects with chronic pancreatitis who undergo total pancreatectomy with auto islet transplantation.
- Trial name
- NCT03097185
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Baylor Research Institute
Chronic Pain, Pancreatitis
Scrambler Therapy in Chronic Pancreatitis
The investigators will enroll adults with chronic pancreatitis who have persistent abdominal pain not relieved by standard treatments.
- Conditions
- Chronic Pain, Pancreatitis, Chronic Pancreatitis
- Trial name
- NCT07174609
- Testing
- Scrambler Therapy
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Johns Hopkins University
Pancreatitis
SARcopenia in Patients With ChrOnic PANcreatitis: the SARCOPAN Study
Sarcopenia is a complex multifactorial syndrome which could be present in older age (primary sarcopenia) or earlier in chronic disease (secondary sarcopenia).
- Trial name
- SARCOPAN (NCT06092307)
- Testing
- Bioelectrical impedance, Handgrip strength test, muscle ultrasound.
- Where
- Italy
- Volunteers
- 98 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Chronic Pancreatitis, Recurrent Acute Pancreatitis
Malabsorption Blood Test (MBT) to Determine Exocrine Pancreatic Function and Related Quality of Life in Chronic Pancreatitis
This project uses the Malabsorption Blood Test (MBT) to identify patients with recurrent acute or chronic pancreatitis who have mild to moderate exocrine pancreatic insufficiency.
- Conditions
- Chronic Pancreatitis, Recurrent Acute Pancreatitis, Exocrine Pancreatic Insufficiency
- Trial name
- MBT (NCT07418593)
- Testing
- Pancreatic Enzyme Replacement Therapy, MBT1, MBT 2
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Anna Evans Phillips
Chronic Pancreatitis, Pain Management
Neural Sensitisation and Neuropsychological Alterations in Painful Chronic Pancreatitis
Chronic pancreatitis (CP) is a progressive inflammatory disease in which chronic abdominal pain affects up to 80% of patients and remains difficult to manage despite treatment of pancreatic pathology.
- Trial name
- NEURO-CP (NCT07707609)
- Testing
- Comprehensive Neuropsychological Assessment, Resting-State Functional MRI (fMRI), Magnetic Resonance Spectroscopy (MRS)
- Where
- India
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Asian Institute of Gastroenterology, India
Adenocarcinoma Pancreas, Chronic Pancreatitis
Contrast Enhanced Harmonic Endoscopic Ultrasound (CEH-EUS) in Focal Pancreatic Masses
The aim of the study is to assess the accuracy of real-time perfusion imaging pattern of pancreatic focal lesions visualized by contrast-enhanced harmonic endoscopic ultrasound (CEH-EUS) for the differential diagnosis between…
- Trial name
- NCT01315548
- Where
- 14 sites in Denmark, France and 6 more
- Volunteers
- 210 people
- Sponsor
- University of Medicine and Pharmacy Craiova
Pancreatic Cancer, Cancer of the Duodenum
Early Oral Versus Enteral Nutrition After Pancreatoduodenectomy
Pancreatoduodenectomy carries high morbidity rates even in high-volume centers. Postoperative complications often preclude or delay adequate oral nutrition and nutritional support may be required.
- Conditions
- Pancreatic Cancer, Cancer of the Duodenum, Cholangiocarcinoma, Chronic Pancreatitis
- Trial name
- NCT01642875
- Testing
- Enteral nutrition, Oral nutrition
- Where
- Poland
- Volunteers
- 96 people
- Sponsor
- Medical University of Warsaw
Chronic Pancreatitis, Diabetes
The Characteristics of Blood Glucose Profile and the Changes of Hormones in PPDM-C Population
The purpose of this study was to explore the characteristics of blood glucose spectrum, changes of endocrine/exocrine pancreatic function and the correlation between them in patients with PPDM-C.
- Trial name
- NCT06826729
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Shanghai Changzheng Hospital
Pancreatitis, Chronic, Abdominal Pain
Δ9-THC (Namisol®) in Chronic Pancreatitis Patients Suffering From Persistent Abdominal Pain
Abdominal pain resulting from chronic pancreatitis (CP) is often recurrent, intense and long-lasting, and is extremely difficult to treat.
- Conditions
- Pancreatitis, Chronic, Abdominal Pain, Chronic Pain
- Trial name
- NCT01551511
- Testing
- Tetrahydrocannabinol
- Where
- Netherlands
- Volunteers
- 29 people
- Sponsor
- Radboud University Medical Center
Chronic Pancreatitis
A Pilot Study in Endoscopic Therapy on Quality of Life and Pain in Chronic Pancreatitis
This study is a prospective study designed to assess the effect of pancreatic endotherapy on quality of life, pain levels, pancreatic exocrine function, and endocrine function.
- Trial name
- EQuiPP (NCT05012150)
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Ohio State University
Pancreatogenic Type 3C Diabetes Mellitus
Effect of Continuous Glucose Monitoring on Hypoglycemia in Adults With Pancreatogenic Diabetes
This study will investigate the effect of continuous glucose monitoring (CGM) (compared to self-monitoring) on hypoglycemia and glycemic control in patients with insulin-treated pancreatogenic diabetes.
- Trial name
- NCT05550480
- Testing
- Continuous glucose monitoring
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Aalborg University Hospital
Chronic Pancreatitis
Pirfenidone as Treatment of Chronic Pancreatitis
The proposed project is focused towards evaluation of Pirfenidone as a novel therapeutic strategy in patients with chronic pancreatitis (CP).
- Trial name
- PATCH (NCT07755813)
- Testing
- Pirfenidone 267 mg Oral Tablet, PROMIS-Global Health, Comprehensive Pain Assessment Tool
- Volunteers
- 60 people
- Sponsor
- Vikas Dudeja
Chronic Pancreatitis, Exocrine Pancreas Carcinoma
Biospecimen Collection to Identify Gene Mutations for High Risk Pancreatic Cancer in Pediatric Patients, INSPPIRE 2 Study
This clinical trial collects blood, saliva, urine, or stool samples to help identify possible genetic mutations that may increase a person's chance at developing pancreatic cancer.
- Conditions
- Chronic Pancreatitis, Exocrine Pancreas Carcinoma, Recurrent Acute Pancreatitis
- Trial name
- NCT06651580
- Testing
- Biospecimen Collection, Quality-of-Life Assessment, Questionnaire Administration
- Where
- 26 sites in United States, Australia and 2 more
- Volunteers
- 1,600 people
- Sponsor
- M.D. Anderson Cancer Center
Chronic Pancreatitis, Idiopathic Chronic Pancreatitis
Classification and Comparison of Early-onset and Late-onset Idiopathic Chronic Pancreatitis
Classification of early-onset idiopathic chronic pancreatitis (EOICP) and late-onset idiopathic chronic pancreatitis (LOICP) was proposed based on bimodal distribution of age at onset of idiopathic chronic pancreatitis (ICP).
- Trial name
- NCT03953937
- Where
- China
- Volunteers
- 1,633 people
- Sponsor
- Changhai Hospital
Chronic Pancreatitis
Endoscopic Versus Surgical Treatment of Chronic Pancreatitis
Chronic pancreatitis is a progressive inflammatory disease of the pancreas characterized by destruction of pancreatic parenchyma and subsequent fibrosis.
- Trial name
- NCT01520675
- Testing
- surgery, Endoscopic therapy
- Where
- India
- Volunteers
- 50 people
- Sponsor
- All India Institute of Medical Sciences
Chronic Pancreatitis
Predictive Biomarker for Endoscopic Therapy in Chronic Pancreatitis
This is an observational prospective study to develop predictive biomarkers for pain response in participants with chronic pancreatitis scheduled for endoscopic therapy.
- Trial name
- NCT06267365
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- NYU Langone Health
Common Bile Duct Stricture
Covered Metallic Stents for First-Line Treatment of Benign Bile Duct Strictures
The current standard of care for benign bile duct strictures involves placement of multiple plastic stents under endoscopic and fluoroscopic guidance to progressively dilate or stretch it open.
- Trial name
- NCT01221311
- Testing
- Fully covered Metallic Stent, Plastic Stent
- Where
- 8 sites in United States, United Kingdom
- Volunteers
- 112 people
- Sponsor
- Medical University of South Carolina
Pancreatic Cancer, Pancreas Cancer
Pancreatic Cancer Early Detection Program
Early detection testing is recommended for individuals at elevated risk for the development of Pancreatic Cancer. This Protocol will define sufficiently elevated risk as either equal to or greater than five times the general…
- Conditions
- Pancreatic Cancer, Pancreas Cancer, Pancreatic Adenocarcinoma, Familial Pancreatic Cancer
- Trial name
- PCEDP (NCT02206360)
- Testing
- Endoscopic Ultrasound, Magnetic Resonance Imaging (MRI)
- Where
- United States
- Volunteers
- 181 people
- Sponsor
- White Plains Hospital