Clinical trials: Panic; Agoraphobia
Anxiety, Anxiety Acute
Anxiety Skills Study
The purposes of this study are: (1) to identify baseline predictors of relative success in cognitive, behavioral, and mindfulness-based treatments for anxiety, (2) explore who benefits from a brief, video-based skill training…
- Conditions
- Anxiety, Anxiety Acute, Anxiety Chronic, Anxiety and Mood Disorders
- Trial name
- NCT07774481
- Testing
- Cognitive therapy, Behavioral therapy, Mindfulness-based therapy
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- Ohio State University
Panic Disorder, Agoraphobia
Virtual Reality Exposure Therapy in Agoraphobic Participants
Virtual Reality Exposure Therapy (VRET) is an effective treatment for anxiety disorders, particularly for specific phobias as fear of heights and fear of flying (e.g. Powers \& Emmelkamp, 2008).
- Trial name
- NCT00734370
- Testing
- Virtual Reality Exposure Therapy for agoraphobic participants, Standard exposure in vivo for agoraphobic participants
- Where
- Netherlands
- Volunteers
- 55 people
- Sponsor
- VU University of Amsterdam
Anxiety Disorders, Social Anxiety Disorder
Dimensional Brain Behavior Predictors of CBT Outcomes in Pediatric Anxiety
Anxiety is among the most prevalent, costly and disabling illnesses and tends emerge early in childhood. Cognitive behavioral therapy (CBT) is the first-line treatment for early life anxiety, but as many as 40% of young patients…
- Conditions
- Anxiety Disorders, Social Anxiety Disorder, Social Phobia, Generalized Anxiety Disorder
- Trial name
- Anxiety-CBT (NCT02810171)
- Testing
- Cognitive Behavioral Therapy, Relaxation Therapy
- Where
- United States
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Major Depressive Disorder, Generalized Anxiety Disorder
The Modular Protocol for Mental Health (MPMH)
Currently, our best psychological treatments for anxiety and mood disorders only focus on individual diagnoses. So, there are separate treatments for Panic Disorder, or Depressive Disorder, or Social Anxiety, etc.
- Conditions
- Major Depressive Disorder, Generalized Anxiety Disorder, Posttraumatic Stress Disorder, Social Anxiety Disorder
- Trial name
- MPMH (NCT03143634)
- Testing
- The Modular Protocol for Mental Health, Treatment-as-usual
- Where
- United Kingdom
- Volunteers
- 43 people
- Sponsor
- Medical Research Council Cognition and Brain Sciences Unit
Panic Disorder, Agoraphobia
Providing Tools for Effective Care and Treatment of Anxiety Disorders
PROTECT-AD is a cognitive behavioral treatment study involving highly qualified psychotherapeutic centers at seven German universities.
- Conditions
- Panic Disorder, Agoraphobia, Specific Phobias, Social Anxiety Disorder
- Trial name
- PROTECT-AD (NCT02605668)
- Testing
- Intensified psychological intervention, Standard intervention
- Where
- Germany
- Volunteers
- 726 people
- Sponsor
- Technische Universität Dresden
Posttraumatic Stress Disorder (PTSD), Generalized Anxiety Disorder (GAD)
Metacognitive Therapy vs Unified Protocol for Patients With Comorbid Anxiety Disorders
The primary goal of this randomized controlled trial is to compare the effectiveness of two transdiagnostic psychological treatments, Metacognitive Therapy (MCT) and the Unified Protocol for Transdiagnostic Treatment of Emotional…
- Conditions
- Posttraumatic Stress Disorder (PTSD), Generalized Anxiety Disorder (GAD), Social Anxiety Disorder (SAD), Panic Disorder (With or Without Agoraphobia)
- Trial name
- NCT06971692
- Testing
- Metacognitive therapy (MCT), Unified protocol (UP)
- Where
- Sweden
- Volunteers
- 114 people
- Sponsor
- Karolinska Institutet
Panic Disorder
Physical Activity and Cognitive Behavioural Therapy in Panic Disorder
Physical activity (treadmill) supports the effect of cognitive behavioural therapy in patients with panic disorder with/without agoraphobia
- Trial name
- NCT01788800
- Testing
- Cognitive Behavioural Therapy (CBT)
- Volunteers
- 46 people
- Sponsor
- Charite University, Berlin, Germany
Obsessive Compulsive Disorder (OCD), Anxiety Disorder of Childhood or Adolescence
Comparative Effectiveness of Internet-based Versus Parent-Coached Cognitive-Behavioral Therapy For Children and Adolescents With Anxiety and OCD
Anxiety disorders in children and adolescents are common and confer significant disability. Cognitive behavioral therapy (CBT) is the recommended treatment for youth with anxiety, yet many families cannot access CBT due to cost…
- Conditions
- Obsessive Compulsive Disorder (OCD), Anxiety Disorder of Childhood or Adolescence, Social Anxiety Disorder of Childhood, Generalized Anxiety Disorder (GAD)
- Trial name
- ASTRO (NCT07024758)
- Testing
- Parent Coached Exposure Therapy, Family Based, Internet-Based Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 174 people
- Sponsor
- Baylor College of Medicine
Panic Disorder, Agoraphobia
Physical Activity and Cognitive Behavioural Therapy in Panic Disorder and Agoraphobia
Physical activity (treadmill) prior to in-vivo exposure supports the effect of cognitive behavioural therapy in patients with panic disorder and agoraphobia.
- Trial name
- NCT01928810
- Testing
- Cognitive Behavioural Therapy
- Volunteers
- 78 people
- Sponsor
- Charite University, Berlin, Germany
Panic Disorder, Agoraphobia
Mechanisms of Panic Disorders Treatment
Investigation of mechanisms of exposure based learning by 1. Investigating the effects of fear augmentation by interoceptive exposure during in vivo exposure 2.
- Conditions
- Panic Disorder, Agoraphobia, Panic Attacks
- Trial name
- NCT01323556
- Testing
- Cognitive Behavioural Therapy (CBT)
- Where
- Germany
- Volunteers
- 180 people
- Sponsor
- University Medicine Greifswald
Obsessive-Compulsive Disorder in Children, Social Anxiety Disorder of Childhood
Parent-based Treatment for Youth With Anxiety and Obsessive-compulsive Disorder
Anxiety and obsessive-compulsive disorders are the most common mental health disorders in childhood and adolescence. A parenting intervention for youth with anxiety, called Supportive Parenting of Anxious Childhood Emotions…
- Conditions
- Obsessive-Compulsive Disorder in Children, Social Anxiety Disorder of Childhood, Obsessive-Compulsive Disorder in Adolescence, Separation Anxiety
- Trial name
- NCT04922502
- Testing
- Standard SPACE, Bibliotherapy, low therapist contact SPACE
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Agoraphobia; Panic, Social Anxiety Disorder
Differential Effects of in Vivo and Virtual Exposure Therapy in Agoraphobia
Anxiety disorders, including agoraphobia, are prevalent in the German population, leading affected individuals to avoid specific places like crowds or public transport.
- Trial name
- VRExpo (NCT06514495)
- Testing
- Therapy
- Where
- Germany
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Johannes Gutenberg University Mainz
Panic Disorder, Agoraphobia
Treatment of Panic Disorder: Long Term Strategies
Cognitive behavior therapy (CBT) with or without medication has been used in the treatment of panic disorder (PD). The purpose of this study is 1) to determine whether nine months of maintenance cognitive-behavior therapy (CBT)…
- Trial name
- NCT00000368
- Testing
- Cognitive behavior therapy, Paroxetine or other medication - algorithm used
- Where
- 4 sites in United States
- Volunteers
- 379 people
- Sponsor
- New York State Psychiatric Institute
Anxiety Disorders, Specific Phobia
Analyzing the Benefits of Using SYMPTOMS-JIT for in Vivo Exposure in Anxiety Disorders
The aim of this study is to develop and test the efficacy of first-of-its-kind, fully instrumented sensor-based smartphone-guided in-vivo exposure therapy using a just-in-time intervention for anxiety disorder.
- Conditions
- Anxiety Disorders, Specific Phobia, Panic Disorder, Agoraphobia
- Trial name
- NCT06788119
- Testing
- Cognitive behavioral therapy with in vivo exposure, Cognitive behavorial therapy with in vivo exposure plus SYMPTOMS-JIT
- Where
- Spain
- Volunteers
- 158 people
- Sponsor
- Universitat Jaume I
Anxiety Disorders
Schema Therapy for Treatment-resistant Anxiety Disorders
The aim of this study is to assess the cost-effectiveness of schema therapy compared to treatment as usual (TAU) in patients with treatment-resistant anxiety disorders.
- Trial name
- PaDoLA (NCT06298695)
- Testing
- Individual Schema Therapy, TAU
- Volunteers
- 172 people
- Sponsor
- Amsterdam UMC, location VUmc
Panic Disorder, Agoraphobia
Cognitive Behavior Psychotherapy in Panic Disorder
The objective of this study in cognitive-behavioural therapy (CBT) was to demonstrate the preparation of the patient with panic disorder for agoraphobic exposures.
- Trial name
- NCT01025908
- Testing
- Psychotherapy, Supportative psychotherapy
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Universidade Federal do Rio de Janeiro
Major Depressive Disorder, Posttraumatic Stress Disorder
Comparing Individual Therapies for Veterans With Depression, PTSD, and Panic Disorder
Cognitive behavioral therapy (CBT) is a brief, efficient, and effective treatment for individuals with depressive/anxiety disorders.
- Conditions
- Major Depressive Disorder, Posttraumatic Stress Disorder, Panic Disorder and Agoraphobia
- Trial name
- NCT04293341
- Testing
- Transdiagnostic Behavior Therapy, Cognitive Processing Therapy for PTSD, Cognitive Behavioral Therapy for MDD
- Where
- United States
- Volunteers
- 304 people
- Sponsor
- VA Office of Research and Development
Obsessive Compulsive Disorder (OCD), Pediatric Anxiety Disorders
Testing Delivery Modalities of Team-Based CBT for Pediatric Anxiety in Community Health Settings.
The purpose of this study is to test how the delivery of Cognitive Behavioral Therapy (CBT) for pediatric anxiety and OCD via different methods might increase its availability and effectiveness.
- Conditions
- Obsessive Compulsive Disorder (OCD), Pediatric Anxiety Disorders, Anxiety Disorder, Anxiety
- Trial name
- IMPACT-RI (NCT06934525)
- Testing
- Team-delivered, exposure-based CBT
- Where
- United States
- Volunteers
- 501 people
- Sponsor
- Bradley Hospital
Agoraphobia
Augmentation of Psychotherapy With D-Cycloserine in Agoraphobia
Since decades, D-Cycloserine (DCS, drug class: Oxazolidinone) is proven to be an effective antibiotic agent in the treatment of tuberculosis.
- Trial name
- Exposure-DCS (NCT01928823)
- Testing
- CBT, D-Cycloserine
- Where
- Germany
- Volunteers
- 73 people
- Sponsor
- Charite University, Berlin, Germany
Vestibular Diseases, Agoraphobia
Pilot Study of Vestibular Rehabilitation Training for Panic Disorder With Vestibular Dysfunction
OBJECTIVES: I. Evaluate whether vestibular rehabilitation training is of value in reducing anxiety symptoms in patients with panic disorder with or without agoraphobia who have vestibular dysfunction as identified by clinical…
- Conditions
- Vestibular Diseases, Agoraphobia, Panic Disorder
- Trial name
- NCT00004366
- Testing
- Physical therapy
- Volunteers
- 20 people
- Sponsor
- National Center for Research Resources (NCRR)