Clinical trials: Panic
Anxiety, Panic Disorder
Investigation of Pathogenic Gut Microbiota Patterns in Anxiety, Depression and Panic Disorders
This study aims to investigate the etiology of anxiety, depression, and panic disorders, providing new evidence and insights into the root causes and effective treatments, potentially offering a novel approach to achieving…
- Conditions
- Anxiety, Panic Disorder, Mood Disorders, Depression
- Trial name
- NCT07268729
- Testing
- H pylori stool test, Bacterial stool analysis
- Where
- Canada
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Anxiety Disorder, Panic Disorder
Vestibular Dysfunction In Adult Patients With Panic Disorder With or Without Agoraphobia
OBJECTIVES: I. Determine whether the prevalence of abnormalities on clinical vestibular (balance) tests is higher in panic disorder with agoraphobia than in uncomplicated panic disorder and nonpanic anxiety disorder. II.
- Trial name
- NCT00004367
- Testing
- Clinical vestibular tests
- Where
- United States
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- National Center for Research Resources (NCRR)
Panic Disorder, Healthy
Effects of Caffeine on Anxiety, Emotional Processing, Approach-avoidance Behavior, and Interoception in Panic Disorder
The current study is a placebo-controlled, double-blind, randomized controlled study using a cross-over design, including participants with Panic disorder and healthy controls.
- Trial name
- NCT05261594
- Testing
- Caffeine
- Where
- Sweden
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Panic Disorder
Different Neural Circuit Mechanisms Between Cognitive Therapy and Behavior Therapy for Patients With Panic Disorder: a Dynamic Research
Cognitive behavioral therapy (CBT), which includes cognitive therapy (CT) and behavioral therapy (BT), is the first-line treatment for patients with panic disorder (PD). However, the neural mechanism of CBT is unknown.
- Trial name
- NCT03199625
- Testing
- Cognitive therapy, Behavior therapy, SSRI antidepressants
- Where
- China
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Nanjing Medical University
Schizophrenia Disorders, Major Depression
Non-Coding RNAs Gene Expression in Psychiatric Disorders
This study aims to investigate whether specific non-coding RNAs, molecules involved in the regulation of gene expression, are altered in individuals with psychiatric disorders such as schizophrenia, bipolar disorder, major…
- Conditions
- Schizophrenia Disorders, Major Depression, Bipolar Affective Disorders, Obsessive Compulsive Disorder (OCD)
- Trial name
- PsiRNA26 (NCT07649993)
- Testing
- Reverse Transcription Quantitative Polymerase Chain Reaction
- Where
- 5 sites in Italy
- Volunteers
- 384 people, healthy volunteers welcome
- Sponsor
- Carmen Concerto
Panic Disorder
Investigations of Factors Associated With Treatment Response and Prognosis in Anxiety Disorders
The purpose of this study is to build a comprehensive brain and behavioral dataset on anxiety disorders and identify clinical factors related to treatment response and prognosis in patients with anxiety disorders.
- Trial name
- IRPA (NCT06773585)
- Testing
- Psychiatric scale assessments, VR-Based Behavioral Assessment, Brain MRI
- Where
- South Korea
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- Kangbuk Samsung Hospital
Social Anxiety, Major Depression Mild
Transdiagnostic REBT Prevention Program for Adolescents
Anxiety and depressive disorders are common in adolescents, however they are often unrecognized. Rational emotive behavioral therapy (REBT), a form of cognitive behavioral therapy (CBT) is efficient for children and adolescents.
- Conditions
- Social Anxiety, Major Depression Mild, Panic Disorder, Specific Phobia
- Trial name
- NCT02756507
- Testing
- video-based transdiagnostic REBT, Wait list
- Where
- Romania
- Volunteers
- 381 people, healthy volunteers welcome
- Sponsor
- Babes-Bolyai University
Panic Disorder
Changes of Cerebral Glucose Metabolism After 12 Weeks of Paroxetine Treatment in Panic Disorder
Panic disorder is one of the most prevalent and disabling psychiatric disorders. Brain regions such as amygdala, hippocampus, periaqueductal gray (PAG), locus coeruleus, parahippocampal gyrus, frontal cortex, and thalamus has…
- Trial name
- NCT00767754
- Testing
- Paxil CR
- Where
- South Korea
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Panic Disorder
Improving Access To Services to Community Based Outpatient Clinics (CBOC's)
The purpose of this study is to examine the feasibility of delivering IPCT in three rural VA community based outpatient clinics (CBOCs).
- Trial name
- NCT01346241
- Testing
- Intensive Panic Control Treatment (IPCT)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Michael E. DeBakey VA Medical Center
Panic Disorder
Efficacy of Treatment for Panic Disorder
The purpose of these questionnaires is to give us an overview of how panic has affected your life and perhaps also to give us some clues about things that may have set you up to experience panic.
- Trial name
- NCT00456768
- Where
- Canada
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Bipolar Disorder, Panic Disorder
Quetiapine SR and Divalproex Sodium ER in the Treatment of Anxiety in Bipolar Disorder With Panic Disorder and/or GAD
The specific aim of this study is to evaluate the efficacy, tolerability, and safety of quetiapine SR monotherapy and divalproex sodium ER monotherapy in comparison to placebo in the treatment of ambulatory bipolar disorder with…
- Conditions
- Bipolar Disorder, Panic Disorder, Generalized Anxiety Disorder
- Trial name
- NCT00579280
- Testing
- quetiapine SR, divalproex sodium ER
- Where
- 3 sites in United States
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Social Anxiety, Generalized Anxiety
Imagery Rescripting and Imaginal Exposure for Anxiety Symptoms
This study will recruit 460 participants who self-report high symptoms of anxiety. Participants will be randomly assigned to one of 4 groups: one analog intervention of Imagery Rescripting (IR) for memories, an analog…
- Conditions
- Social Anxiety, Generalized Anxiety, Obsessive-Compulsive Symptom, Panic
- Trial name
- NCT05292807
- Testing
- Imaginal exposure for memories, Imaginal exposure for future events, Imagery rescripting for memories
- Where
- Israel
- Volunteers
- 460 people, healthy volunteers welcome
- Sponsor
- Hebrew University of Jerusalem
Healthy
A Study in Healthy Men to Test Whether BI 1358894 Reduces Druginduced Panic Symptoms
The main objective of this trial is to investigate the pharmacodynamic effects of a single dose of BI 1358894 on CCK-4- induced anxiogenic/ panic-like symptoms using the PSS in preselected CCK-4 sensitive healthy volunteers.
- Trial name
- NCT03904576
- Testing
- BI 1358894
- Where
- Netherlands
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Generalized Anxiety Disorder, Social Anxiety Disorder
Predicting Treatment Response to Exposure Therapy Using Carbon Dioxide
Anxiety disorders affect over a quarter of the population, yet very little is known about the variables that predict treatment outcome.
- Conditions
- Generalized Anxiety Disorder, Social Anxiety Disorder, Panic Disorder, Agoraphobia
- Trial name
- NCT03925987
- Testing
- Exposure therapy
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Laureate Institute for Brain Research, Inc.
Anxiety Disorder/Anxiety State
Online Acceptance and Commitment Therapy for Reducing Anxiety
The main objective of this study is to test the effectiveness of an Internet-delivered Acceptance and Commitment Therapy (ACT) program in reducing anxiety symptoms.
- Trial name
- NCT03074669
- Testing
- ACT program
- Where
- Romania
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- West University of Timisoara
Anxiety, Panic Disorder
Ventilatory Physiology in Children at Risk for Anxiety
The importance of the proposed research project derives from a steady accumulation of research findings on the relationship between respiration and anxiety.
- Trial name
- NCT00101777
- Where
- United States
- Volunteers
- 479 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Anxiety Disorders
Expectation of Unpleasant Events in Anxiety Disorders
Fear and anxiety are normal responses to a threat. However, anxiety is considered abnormal when the response to the threat is excessive or inappropriate.
- Trial name
- NCT00055224
- Testing
- Threat of shock
- Where
- United States
- Volunteers
- 921 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Bipolar Disorder, Panic Disorder
Ziprasidone in Bipolar Disorder With Comorbid Lifetime Panic or Generalized Anxiety Disorder(GAD)
The specific aim of this study is to evaluate the efficacy, tolerability, and safety of ziprasidone monotherapy in comparison to placebo in the treatment of ambulatory bipolar disorder with co-morbid lifetime panic disorder or…
- Conditions
- Bipolar Disorder, Panic Disorder, Generalized Anxiety Disorder
- Trial name
- PfizerAnxty (NCT01172652)
- Testing
- Ziprasidone
- Where
- 3 sites in United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- VA Palo Alto Health Care System
Mental Disorder, Perinatal
Perinatal Mental Health Care in Switzerland
This qualitative study with quantitative elements examines the health care provided to women who suffered from mental disorder during pregnancy and / or in the first year after birth (i.e. during the perinatal phase).
- Conditions
- Mental Disorder, Perinatal, Depression, Anxiety Disorders
- Trial name
- MADRE (NCT04185896)
- Where
- Switzerland
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Bern University of Applied Sciences
Panic Disorder, Healthy
Evaluation of Substance P Neurotransmission in Panic Disorder by PET Imaging of NK1 Receptors With [18F]SPA-RQ
This study is designed to observe the effects of a panic attack in patients with panic disorders and to demonstrate the involvement of Substance P in panic disorder, and thereby, further our understanding of its role in this…
- Trial name
- NCT00088738
- Testing
- [18F] SPA-RQ
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)