Clinical trials: Papillary Microcarcinoma of the Thyroid
Papillary Thyroid Cancer, Papillary Thyroid Carcinoma
Active Surveillance and Surgery Outcomes in Low Risk Papillary Thyroid Cancer
This is a prospective, observational, multi-center study examining the long-term outcomes of patients with small, low risk papillary thyroid cancer who offered the choice of active surveillance (close follow-up to monitor for…
- Conditions
- Papillary Thyroid Cancer, Papillary Thyroid Carcinoma, Papillary Microcarcinoma of the Thyroid
- Trial name
- NCT04624477
- Where
- 8 sites in Canada
- Volunteers
- 450 people
- Sponsor
- University Health Network, Toronto
Papillary Thyroid Microcarcinoma
Genetic Expression Alteration Affect on Lateral Neck Node Metastasis of Thyroid Papillary Microcarcinoma : Microarray Analysis
In this study, the investigators look at the genetic expressional alteration which influenced on the early lateral neck node metastasis in thyroid papillary microcarcinoma.
- Trial name
- NCT01384669
- Where
- South Korea
- Volunteers
- 29 people
- Sponsor
- Yonsei University
Papillary Thyroid Cancer, Papillary Thyroid Microcarcinoma
Treatment of Papillary Thyroid Carcinoma With Radiofrequency Ablation
Investigators intend to evaluate the efficiency of Radiofrequency ablation (RFA) therapy to treat papillary thyroid carcinoma.
- Trial name
- NCT04129411
- Testing
- RFA
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Mayo Clinic
Carcinoma
Extent of Central Lymph Node Dissection in Papillary Thyroid Microcarcinoma
Occult lymph node metastasis is common in micro papillary thyroid cancer. However, the role of lymph node dissection in the treatment of microPTC remains controversial.
- Trial name
- NCT01149161
- Testing
- Routine central neck dissection
- Where
- South Korea
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Thyroid Cancer, Lymph Node Metastases
Predictive Factors of Lymph Node Metastasis in Patients With Papillary Microcarcinoma of the Thyroid
Papillary thyroid microcarcinoma (PTMC), defined as a tumor with larger diameter ≤ 1 cm, is considered a tumor with an indolent course and an excellent prognosis.
- Trial name
- NCT04274829
- Testing
- Thyroidecomt and lymphectomy
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- University of Cagliari
Papillary Thyroid Microcarcinoma, Thyroid
Laser Ablation of Papillary Thyroid Microcarcinoma
The purpose of this study is to explore whether percutaneous laser ablation (PLA) is a safe and effective alternative to removing papillary thyroid microcarcinoma (PTMC) with surgery.
- Conditions
- Papillary Thyroid Microcarcinoma, Thyroid, Thyroid Cancer
- Trial name
- NCT04623801
- Testing
- Percutaneous Laser Ablation (PLA)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Thyroid Cancer, Treatment Related Cancer
A Multicenter Trial of PLA vs. Surgery for Treating PTMC
This is a multicenter prospective controlled trial of percutaneous laser ablation(PLA) versus conventional surgery for the treatment of papillary thyroid microcarcinoma (PTMC).
- Trial name
- NCT03377829
- Testing
- PLA, Thyroid Surgery
- Where
- 13 sites in China, Italy
- Volunteers
- 200 people
- Sponsor
- WeiWei Zhan
Papillary Thyroid Microcarcinoma
Safety and Quality of Life of Three Treatment Strategies for Low-Risk Papillary Thyroid Microcarcinoma
This is a prospective observational patient registry study designed to evaluate the safety and quality of life associated with three treatment strategies for patients diagnosed with low-risk papillary thyroid microcarcinoma…
- Trial name
- PTMC-3S (NCT07249125)
- Where
- China
- Volunteers
- 1,630 people
- Sponsor
- Xijing Hospital
Papillary Thyroid Microcarcinoma
Long-term Outcomes of Total Thyroidectomy Versus Less Than Total Thyroidectomy for Papillary Thyroid Microcarcinoma
Although the vast majority of patients with Papillary Thyroid Microcarcinoma (PTMC) have excellent long-term outcomes, some patients experience tumor recurrence, either locally or, less frequently, as distant metastases, with…
- Trial name
- NCT01648569
- Where
- South Korea
- Volunteers
- 2,014 people
- Sponsor
- Korean Association of Endocrine Surgeons
Papillary Microcarcinoma
Genomic Predictors of Papillary Microcarcinoma Disease Progression
The study is being done to answer the following question: What are the specific clinical and molecular features that will help us predict which small thyroid cancers are likely to grow and be problematic? Therefore, the purpose…
- Trial name
- NCT02363595
- Where
- United States
- Volunteers
- 750 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Papillary Microcarcinoma of the Thyroid
Active Surveillance Versus Surgery in Thyroid Papillary Microcarcinoma
The primary objective of this study is to evaluate the outcome of two treatment approaches (immediate surgery or close follow-up) in patients with papillary thyroid microcarcinoma (mPTc) .
- Trial name
- MITICA (NCT04129281)
- Testing
- Surgery
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- National Cancer Institute, Naples
Papillary Thyroid Microcarcinoma
Minimally Invasive Treatments of the Thyroid
This is a prospective cohort study to test Minimally Invasive Treatments of the Thyroid (MITT) as potential alternative to surgery in patients with Papillary Thyroid MicroCarcinoma (PTMC)
- Trial name
- MIPA-MITT (NCT06333587)
- Testing
- image-guided thermal ablation
- Where
- Italy
- Volunteers
- 270 people
- Sponsor
- European Institute of Oncology
Papillary Thyroid Microcarcinoma
A Trial Comparing USG-HIFU vs AS in Management of Low-risk PTMC
Papillary thyroid microcarcinoma (PTMC) is a common tumor in Hong Kong. Early immediate surgery has traditionally been recommended.
- Trial name
- NCT03327636
- Testing
- Echopulse
- Where
- Hong Kong
- Volunteers
- 103 people
- Sponsor
- The University of Hong Kong
Papillary Thyroid Microcarcinoma, Microbiome
Microbiome and Papillary Thyroid Microcarcinoma
It has been shown that gut microbiome and microbiome metabolism can regulate or control the initiation of a cancer process. To the best of the investigators knowledge, no study has directly shown the relationship of the thyroid…
- Trial name
- NCT04376203
- Testing
- Thyroidectomy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Ioannina
Thyroid Cancer
Impact of Papillary Microcarcinoma Terminology on Patients Treatment Preferences: a Cross Sectional Survey
To explore how a clinical sample of patients with thyroid nodules (men and women) with no history of thyroid cancer would make decisions about treatments based on different terminology used to describe papillary thyroid cancer…
- Trial name
- NCT02726282
- Where
- United States
- Sponsor
- Mayo Clinic
Thyroid Cancer, Papillary Microcarcinoma
Treatment Decision-Making Among Patients Diagnosed With Papillary Microcarcinoma and Their Significant Others
The purpose of this study is to understand more about why some patients choose to have surgery to treat their papillary microcarcinoma (PMC) and others choose to have their papillary microcarcinoma (PMC) regularly watched by…
- Trial name
- NCT01392222
- Testing
- Focus groups
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center