Clinical trials: Papillary Thyroid Microcarcinoma
Thyroid Cancer, Papillary Thyroid Microcarcinoma
Multicenter Comparison of Thermal Ablation Versus Thyroid Lobectomy for Subcapsular Papillary Thyroid Microcarcinoma
To compare the clinical outcomes of Thermal ablation with those of thyroid lobectomy in patients with subcapsular papillary thyroid microcarcinoma.
- Trial name
- NCT06583057
- Testing
- Thermal ablation, Thyroid lobectomy
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Chinese PLA General Hospital
Papillary Thyroid Microcarcinoma
PMRA and Shapley-Based Machine Learning for Predicting Lymph Node Metastasis in Central Subregions of Clinically Node-Negative Papillary Thyroid Microcarcinoma: a Prospective Multicenter Validation and Development of a Web Calculator
Background:Management of clinically node-negative(cN0) papillary thyroid microcarcinoma (PTMC) is complicated by high occult lymph node metastasis (LNM) rates.
- Trial name
- PMRA (NCT06871956)
- Testing
- PMRA and Shapley-Based Machine Learning for Predicting Lymph Node Metastasis in Central Subregions of Clinically Node-Negative Papillary Thyroid Microcarcinoma
- Where
- China
- Volunteers
- 4,882 people
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
Papillary Thyroid Microcarcinoma
Safety and Quality of Life of Three Treatment Strategies for Low-Risk Papillary Thyroid Microcarcinoma
This is a prospective observational patient registry study designed to evaluate the safety and quality of life associated with three treatment strategies for patients diagnosed with low-risk papillary thyroid microcarcinoma…
- Trial name
- PTMC-3S (NCT07249125)
- Where
- China
- Volunteers
- 1,630 people
- Sponsor
- Xijing Hospital
Papillary Thyroid Microcarcinoma
A Trial Comparing USG-HIFU vs AS in Management of Low-risk PTMC
Papillary thyroid microcarcinoma (PTMC) is a common tumor in Hong Kong. Early immediate surgery has traditionally been recommended.
- Trial name
- NCT03327636
- Testing
- Echopulse
- Where
- Hong Kong
- Volunteers
- 103 people
- Sponsor
- The University of Hong Kong
Thyroid Cancer, Papillary Thyroid Microcarcinoma
Active Surveillance on Papillary Thyroid Microcarcinoma
The study is a multi-center prospective cohort study of active surveillance in papillary thyroid cancer with low risk. The purpose of the study is to observe natural course of low risk papillary thyroid cancer in Korean…
- Trial name
- NCT02938702
- Where
- South Korea
- Volunteers
- 1,211 people
- Sponsor
- Seoul National University Hospital
Papillary Thyroid Microcarcinoma
Minimally Invasive Treatments of the Thyroid
This is a prospective cohort study to test Minimally Invasive Treatments of the Thyroid (MITT) as potential alternative to surgery in patients with Papillary Thyroid MicroCarcinoma (PTMC)
- Trial name
- MIPA-MITT (NCT06333587)
- Testing
- image-guided thermal ablation
- Where
- Italy
- Volunteers
- 270 people
- Sponsor
- European Institute of Oncology
Papillary Thyroid Cancer
Percutaneous Ethanol Injection for Primary Papillary Thyroid Microcarcinoma
We assess the effectiveness of percutaneous ethanol ablation for the treatment of thyroid cancer.
- Trial name
- NCT01974284
- Testing
- percutaneous ethanol ablation
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Yale University
Papillary Thyroid Microcarcinoma, Thyroid Cancer
Radiofrequency Ablation of Low Risk Papillary Thyroid Microcarcinoma
This is a single center prospective clinical trial with regard to efficacy and safety of radiofrequency ablation of papillary thyroid microcarcinoma.
- Trial name
- RFAforPTMC (NCT03432299)
- Testing
- RFA for PTMC
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Seoul National University Hospital
Papillary Microcarcinoma
Genomic Predictors of Papillary Microcarcinoma Disease Progression
The study is being done to answer the following question: What are the specific clinical and molecular features that will help us predict which small thyroid cancers are likely to grow and be problematic? Therefore, the purpose…
- Trial name
- NCT02363595
- Where
- United States
- Volunteers
- 750 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Thyroid Cancer, Papillary Microcarcinoma
Treatment Decision-Making Among Patients Diagnosed With Papillary Microcarcinoma and Their Significant Others
The purpose of this study is to understand more about why some patients choose to have surgery to treat their papillary microcarcinoma (PMC) and others choose to have their papillary microcarcinoma (PMC) regularly watched by…
- Trial name
- NCT01392222
- Testing
- Focus groups
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Thyroid Cancer
Prophylactic Central Lymph Node Dissection in Papillary Thyroid Microcarcinoma
The purpose of this study is to determine whether the prophylactic ipsilateral central lymph node dissection is equally effective in the management of papillary thyroid microcarcinoma(PTMC) to the bilateral central lymph node…
- Trial name
- NCT00795782
- Testing
- Prophylactic central lymph node dissection
- Where
- South Korea
- Volunteers
- 258 people
- Sponsor
- Samsung Medical Center
Papillary Thyroid Microcarcinoma
Long-term Outcomes of Total Thyroidectomy Versus Less Than Total Thyroidectomy for Papillary Thyroid Microcarcinoma
Although the vast majority of patients with Papillary Thyroid Microcarcinoma (PTMC) have excellent long-term outcomes, some patients experience tumor recurrence, either locally or, less frequently, as distant metastases, with…
- Trial name
- NCT01648569
- Where
- South Korea
- Volunteers
- 2,014 people
- Sponsor
- Korean Association of Endocrine Surgeons
Papillary Thyroid Cancer
Radiofrequency Ablation of Papillary Thyroid Microcarcinoma
Traditionally, surgery has been the standard recommendation for treating papillary thyroid cancer. The risk of surgery including permanent hoarseness, permanent hypocalcemia, a mid-cervical scar, and the potential for permanent…
- Trial name
- NCT05132205
- Testing
- Radiofrequency Ablation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Johns Hopkins University
Thyroid Cancer, Treatment Related Cancer
A Multicenter Trial of PLA vs. Surgery for Treating PTMC
This is a multicenter prospective controlled trial of percutaneous laser ablation(PLA) versus conventional surgery for the treatment of papillary thyroid microcarcinoma (PTMC).
- Trial name
- NCT03377829
- Testing
- PLA, Thyroid Surgery
- Where
- 13 sites in China, Italy
- Volunteers
- 200 people
- Sponsor
- WeiWei Zhan
Carcinoma
Extent of Central Lymph Node Dissection in Papillary Thyroid Microcarcinoma
Occult lymph node metastasis is common in micro papillary thyroid cancer. However, the role of lymph node dissection in the treatment of microPTC remains controversial.
- Trial name
- NCT01149161
- Testing
- Routine central neck dissection
- Where
- South Korea
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Papillary Thyroid Microcarcinoma
Radiofrequency Ablation Treatment of Low-Risk Papillary Thyroid Carcinomas
Researchers in this study aim to prove the safety and efficacy of radiofrequency ablation in the treatment of a carefully selected low-risk papillary thyroid microcarcinoma patient group.
- Trial name
- NCT07506161
- Testing
- Radiofrequency ablation alone
- Where
- Hungary
- Volunteers
- 27 people
- Sponsor
- Premier G Med Cardio Kft
Thyroid Cancer, Lymph Node Metastases
Predictive Factors of Lymph Node Metastasis in Patients With Papillary Microcarcinoma of the Thyroid
Papillary thyroid microcarcinoma (PTMC), defined as a tumor with larger diameter ≤ 1 cm, is considered a tumor with an indolent course and an excellent prognosis.
- Trial name
- NCT04274829
- Testing
- Thyroidecomt and lymphectomy
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- University of Cagliari
Papillary Thyroid Microcarcinoma
RFA Treatment for Papillary Thyroid Microcarcinoma
Thyroid surgery has always been the mainstay of treatment for thyroid cancer. Thyroid surgery carries a low risk of complications that include recurrent or superior laryngeal nerve injury leading to voice changes…
- Trial name
- NCT05189821
- Testing
- Radiofrequency Ablation
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Columbia University
Papillary Thyroid Microcarcinoma, Thyroid
Laser Ablation of Papillary Thyroid Microcarcinoma
The purpose of this study is to explore whether percutaneous laser ablation (PLA) is a safe and effective alternative to removing papillary thyroid microcarcinoma (PTMC) with surgery.
- Conditions
- Papillary Thyroid Microcarcinoma, Thyroid, Thyroid Cancer
- Trial name
- NCT04623801
- Testing
- Percutaneous Laser Ablation (PLA)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Differentiated Thyroid Cancer (DTC), Papillary Thyroid Microcarcinoma
Decision Aid Efficacy in Low Risk Thyroid Cancer
Low-risk thyroid cancer grows very slowly. More than 99% of patients with this cancer survive for at least 5 years. There are 3 main treatment options: remove the whole thyroid, remove just the part of the thyroid with the cancer…
- Conditions
- Differentiated Thyroid Cancer (DTC), Papillary Thyroid Microcarcinoma, Papillary Thyroid Carcinoma
- Trial name
- NCT07536412
- Testing
- Decision Aid
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of Maryland, Baltimore