Clinical trials: Papilloma Virus, Human
Human Papillomavirus-Related Carcinoma, Oropharyngeal Cancer
HYHOPE: De-intensified Hypofractionated Radiation Therapy for HPV-associated Oropharynx Cancer
This is a single arm Phase I study of de-intensified hypofractionated radiation therapy for favorable human papilloma virus-associated oropharynx cancer.
- Trial name
- NCT04580446
- Testing
- Hypofractionated intensity modulated radiotherapy
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Texas Southwestern Medical Center
Human Papilloma Virus Infection Type 16
Developing a First-void Urine-based Infection Model to Study HPV-specific Antibody-virion Interaction Before and After HPV Vaccination
The current study is an open-label, non-randomized, longitudinal exploratory trial using the licensed Gardasil 9 (9vHPV) vaccine in an off-label context to investigate biological and immunological outcomes in human papillomavirus…
- Trial name
- URVIVE (NCT07407569)
- Testing
- Gardasil 9 (2 dose regimen)
- Where
- 3 sites in Belgium
- Volunteers
- 50 people
- Sponsor
- Universiteit Antwerpen
Human Papillomavirus
Evaluation of a Novel Point-of-Care Diagnostic Test for Human Papillomavirus (HPV)
To learn if new HPV tests can provide the same results as standard HPV tests. The findings from this study may aid in the development of new HPV tests that require less equipment and are more accessible.
- Trial name
- NCT06434337
- Testing
- Novel point-of-care diagnostic test for detecting HPV ("Rice HPV test")
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- M.D. Anderson Cancer Center
Human Papillomavirus (HPV), Medically Assisted Procreation (MAP)
Prevalence of HPV Transmission During Medically Assisted Procreation Procedures
Human PapillomaVirus (HPV) are ones of the main causal agents of sexually transmitted diseases. Numerous HPV genotypes such as 16, 18, 31 or 45 are considered to be at high risk of oncogenicity especially for the anal and…
- Conditions
- Human Papillomavirus (HPV), Medically Assisted Procreation (MAP), Infertility
- Trial name
- AMPAMAVIR (NCT02524223)
- Testing
- Systematic HPV DNA assay in semen and cervicovaginal scrape, Systematic HPV DNA cervicovaginal scrape, systematic HPV Status in newborns in case of pregnancy
- Where
- 5 sites in France
- Volunteers
- 915 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Condylomata Acuminata
Human Papillomavirus (HPV) Types Present in External Genital Warts (EGW) in the Argentinean Population
The summary of this study is to know which HPV types are present in genital warts in Argentinean population.
- Trial name
- NCT01598779
- Where
- Argentina
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Buenos Aires
Human Papillomavirus (HPV) Infection, HPV Vaccination Acceptance/Intention
Effect of Different HPV Education Methods on Vaccination Intention in Young Women
Detailed Description Human papillomavirus (HPV) is one of the leading causes of cervical cancer and can be prevented by vaccination.
- Trial name
- NCT07420556
- Testing
- Video-Based HPV Education, Face-to-Face HPV Education
- Where
- Turkey (Türkiye)
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Emel GÜÇLÜ CİHAN
Human Papillomavirus
Knowledge of 18-19 Years Old About Papillomavirus and HPV Vaccination
Today, cancers associated with papillomavirus infection affect 6,300 new people each year in France, men and women combined. The papillomavirus vaccine is currently the only vaccine that protects against HPV-associated cancers.
- Trial name
- CO-HPV (NCT07418203)
- Testing
- Data collection
- Where
- France
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Université de Reims Champagne-Ardenne
Cervical Intraepithelial Neoplasia
A Pilot Study of EM-1421 for the Treatment of Cervical Intraepithelial Neoplasia
The primary objective of this study is to determine pilot safety and efficacy data for a topical formulation of EM-1421 applied to the cervix of patients with CIN 1, 2, or 3.
- Trial name
- NCT00154089
- Testing
- EM-1421
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Erimos Pharmaceuticals
Oropharyngeal Squamous Cell Carcinoma
Cisplatin or ImmunoTHerapy in Association With Definitive Radiotherapy in HPV-related oropharyngEal Squamous Cell Carcinoma: a Randomized Phase II Trial.
This study is a phase II, multicenter, open-label study that has been designed to evaluate the efficacy and the safety of definitive Radiotherapy (RT) (70 Gy) delivered in combination with the anti-PD-L1 Durvalumab immunotherapy…
- Trial name
- CITHARE (NCT03623646)
- Testing
- Chemoradiotherapy arm, Immunotherapy + Radiotherapy arm
- Where
- 2 sites in France
- Volunteers
- 11 people
- Sponsor
- Institut Claudius Regaud
Recurrent Respiratory Papillomatosis, Papillomavirus Infections
Adjuvant PRGN-2012 in Adult Patients With Recurrent Respiratory Papillomatosis
This is a Phase 1/2 study in patients with a Recurrent Respiratory Papillomatosis (RRP) disease burden that requires repeated surgical procedures for management. RRP is a rare disease caused by the human papillomavirus (HPV).
- Conditions
- Recurrent Respiratory Papillomatosis, Papillomavirus Infections, Papillomaviridae
- Trial name
- NCT04724980
- Testing
- PRGN-2012 - Phase I; Dose Level 1, PRGN-2012 - Phase I; Dose Level 2, PRGN-2012 - Phase II; Dose Level 2
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Precigen, Inc
Oropharyngeal Squamous Cell Carcinoma (OPSCCA), Oropharyngeal Cancer
Intratumoral Lidocaine Injection Before Oropharyngeal Cancer Surgery
Based on evidence that the local anesthetic lidocaine may have anticancer effects, this study will assess the safety and efficacy of intratumoral lidocaine injection at the time of direct laryngoscopy prior to TransOral Robotic…
- Conditions
- Oropharyngeal Squamous Cell Carcinoma (OPSCCA), Oropharyngeal Cancer, Human Papilloma Virus, Squamous Cell Carcinoma
- Trial name
- 856397 (NCT06747390)
- Testing
- Lidocaine 1% Injectable Solution
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Ryan Carey
Human Papillomavirus (HPV)
Perception, Awareness, and Acceptance of Human Papillomavirus Disease and Vaccine Among Parents of Boys Aged 9 to 18 Years
The objectives of this study are: 1. to determine the degree of understanding and perceived risks for human papillomavirus (HPV) disease, to examine and assess attitudes for personal use of HPV vaccine and identify potential…
- Trial name
- NCT01197079
- Testing
- Survey
- Where
- 7 sites in United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Cervical Cancer, Precancerous Condition
Folic Acid Clinical Trial for the Prevention of Cervical Cancer
RATIONALE: Supplements, such as folic acid, may stop or delay the development of cervical cancer in women infected with human papillomavirus.
- Trial name
- NCT00703196
- Testing
- folic acid
- Where
- United States
- Volunteers
- 368 people
- Sponsor
- University of Alabama at Birmingham
Cervical Intraepithelial Neoplasia, Human Papillomavirus
Comparisons of the Effects and Clinical Outcomes of CH2 Vaginal Gel Versus Placebo on CIN1
In Taiwan, Pap smear screen has been offered every year for women over 30 years old since 1995. The incidence of cervical invasive cancer decreased from 25/100,000 person in 1995 to 7.0/100,1000 person in 2016.
- Trial name
- NCT06582004
- Testing
- CH2 vaginal gel
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- National Taiwan University Hospital
Human Papillomavirus, HPV-16
Immunotherapy With E6 T Cell Receptor (TCR) T Cells for Vulvar High-Grade Squamous Intraepithelial Lesions
Background: Vulvar high-grade squamous intraepithelial lesion (HSIL) is caused by infection of the vulva with human papillomavirus (HPV). In a small percentage of cases, vulvar HSIL can turn into cancer.
- Conditions
- Human Papillomavirus, HPV-16, High Grade Squamous Intraepithelial Lesion
- Trial name
- NCT03197025
- Testing
- Aldesleukin, E6 T Cell Receptor (TCR)
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- National Cancer Institute (NCI)
Cervical Cancer
Self-Collection and Human Papillomavirus (HPV) Testing in Unscreened Women: a Feasibility Study in Brazil
Our long-term goal is to decrease cervical cancer incidence and mortality among women in low- and middle-income countries (LMICs) by using the most efficacious and acceptable screening method, particularly among women who do not…
- Trial name
- HPV (NCT03713697)
- Testing
- Pap testing, Self-collection for HPV testing, Choice
- Where
- Brazil
- Volunteers
- 484 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Head and Neck Cancer, Oropharynx Cancer
Stereotactic Boost and Short-course Radiation Therapy for Oropharynx Cancer
This is a randomized clinical trial comparing the outcomes of short-course chemoradiation consisting in stereotactic boost to the gross tumor and de-esclalated chemoradiation to the elective neck in human papilloma associated…
- Conditions
- Head and Neck Cancer, Oropharynx Cancer, Human Papilloma Virus
- Trial name
- SHORT-OPC (NCT04178174)
- Testing
- SABR boost and de-escalated chemoradiation, Standard chemoradiation
- Where
- 2 sites in Canada
- Volunteers
- 360 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Human Papilloma Virus, HIV Infections
ERADICATING CERVICAL CANCER IN KENYA
This is a study of a strategy designed to 1) increase cervical cancer screening using a community-based approach, and 2) determine the efficacy of HPV vaccination in a region of Kenya where half of all children are chronically…
- Trial name
- NCT04774887
- Testing
- HPV vaccine, Merck
- Where
- Kenya
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Indiana University
Human Papilloma Virus, Infections
Impact Of Intralesional Tuberculin Ppd Injection On Anogenital
This clinical study investigates the immunological effects of tuberculin purified protein derivative (TPPD) therapy in patients with anogenital warts (AGW) caused by human papillomavirus (HPV).
- Trial name
- NCT07072065
- Testing
- protein purified derivative
- Where
- Indonesia
- Volunteers
- 24 people
- Sponsor
- Universitas Padjadjaran
Oropharyngeal Squamous Cell Carcinoma (SCC)
Phase 1 Clinical Trial of FluBHPVE6E7 Immunotherapy for HPV16-Associated Oropharyngeal Cancer
A clinical study of an immunotherapy in patients with head or neck cancers associated with the HPV16 virus
- Trial name
- NCT06589609
- Testing
- FluBHPVE6E7
- Where
- Austria
- Volunteers
- 12 people
- Sponsor
- BlueSky Immunotherapies GmbH
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