Clinical trials: Papilloma Virus, Human
Oropharyngeal Cancer, Human Papilloma Virus
Men and Women Offering Understanding of Throat HPV
This study will screen people for oncogenic oral Human Papillomavirus (HPV) infection and antibodies to form a cohort of people who may be at increased risk of HPV-oropharyngeal cancer (HPV-OPC).
- Trial name
- MOUTH (NCT03644563)
- Where
- United States
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Human Papilloma Virus, HPV
Acceptance of Human Papillomavirus Vaccination in Postpartum Women
Worldwide cervical cancer remains a major cause mortality among women. It is estimated that each year over 490,000 women are diagnosed with cervical cancer and more than 270,000 die from the disease.
- Conditions
- Human Papilloma Virus, HPV, Post Partum
- Trial name
- HPV Acceptance (NCT00730704)
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Columbia University
Human Papillomavirus
KAP/WTP and HPV Prevalence Studies in a Developing World Setting (Bamako, Mali)
The Global Alliance to Immunize Against AIDS Vaccine Foundation (GAIA Vaccine Foundation or GAIA VF) proposes to carry out a Knowledge, Attitudes, and Practices (KAP) study in conjunction with a Willingness To Participate (WTP)…
- Trial name
- HPV (NCT01314404)
- Where
- 2 sites in Mali
- Volunteers
- 460 people, healthy volunteers welcome
- Sponsor
- Global Alliance to Immunize Against AIDS Vaccine Foundation
Head and Neck Squamous Cell Carcinoma, Melanoma
RPTR-168 in Patients With Human Papillomavirus Strain 16 (HPV-16) E6/E7 Positive Tumors and Melanoma
The purpose of this study is to assess the safety and tolerability of escalating doses of RPTR-168 as a monotherapy in patients with HPV-16 E6/E7 positive tumors (HNSCC, cervical) and melanoma.
- Conditions
- Head and Neck Squamous Cell Carcinoma, Melanoma, Cervical Cancer
- Trial name
- NCT04762225
- Testing
- RPTR-168
- Where
- 4 sites in United States
- Volunteers
- 7 people
- Sponsor
- Repertoire Immune Medicines
Cervical Intraepithelial Neoplasia, Cervical Cancer
Lot Consistency Clinical Trial of of Recombinant HPV Bivalent Vaccine in 9 to14 Years Old Healthy Female
This study is to evaluate lot-lot consistency of Recombinant Human Papillomavirus Bivalent (Types 16, 18) Vaccine (Escherichia coli) .
- Conditions
- Cervical Intraepithelial Neoplasia, Cervical Cancer, Vaginal Intraepithelial Neoplasia, Vulvar Intraepithelial Neoplasia
- Trial name
- NCT05426148
- Testing
- Recombinant Human Papillomavirus Bivalent (Types 16, 18) Vaccine (Escherichia coli) / Cecolin®
- Where
- China
- Volunteers
- 540 people, healthy volunteers welcome
- Sponsor
- Xiamen Innovax Biotech Co., Ltd
Human Papillomavirus, Cervical Intraepithelial Neoplasia
Evaluating the 2-dose Immunization Schedule of Human Papillomavirus (HPV)-16/18 in Adolescent Females
To evaluate the immune non-inferiority, as measured by antibody responses, of a 2-dose immunization schedule (0, 6 months) of recombinant human papillomavirus virus-like particle vaccine (type 16 and 18 L1 proteins, yeast)…
- Conditions
- Human Papillomavirus, Cervical Intraepithelial Neoplasia, Persistent Infection
- Trial name
- NCT02740777
- Testing
- HPV-16/18 vaccine
- Where
- 2 sites in China
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Shanghai Zerun Biotechnology Co.,Ltd
Health Adults, Teenager
Effectiveness of Interventions for Improving HPV Vaccination Cover
Research Problem and Question: The development of prophylactic vaccines against the human papillomavirus (HPV) marks a major scientific and technological advance in the fight against cervical cancer.
- Trial name
- NCT07113236
- Testing
- Instructions, advices, No instructions
- Where
- Colombia
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Instituto Nacional de Cancerologia, Columbia
Human Papillomavirus, Infection
Human Papillomavirus (HPV) Vaccination in Barretos (Pio XII Foundation - Barretos Cancer Hospital)
PROJECT JUSTIFICATION: Cervical cancer is a serious public health problem in Brazil, and is the cause of significant morbidity and mortality among Brazilian women.
- Trial name
- NCT01159834
- Volunteers
- 1,574 people, healthy volunteers welcome
- Sponsor
- Barretos Cancer Hospital
Human Papillomavirus Infection
A Phase III Trial Evaluates the Efficacy, Immunogenicity and Safety Profile of HPV Vaccine
This study is to demonstrate that the administration of the investigational vaccine can reduce the Combined Incidence of HPV types 6/11/16/18/31/33/45/52/58-related high-grade Cervical Intraepithelial Neoplasia (CIN 2/3)…
- Trial name
- NCT05668572
- Testing
- Recombinant Nonavalent (types 6/11/16/18/31/33/45/52/58) Human Papillomavirus (HPV) Vaccine (Escherichia coli), Recombinant Quadrivalent Human Papillomavirus (Types 6,11,16,18) Vaccine (Saccharomyces cerevisiae)（GARDASIL®）
- Where
- 3 sites in China
- Volunteers
- 12,000 people, healthy volunteers welcome
- Sponsor
- Beijing Health Guard Biotechnology, Inc
Oropharyngeal Human Papillomavirus-Positive Squamous Cell Carcinoma
Prospective Assessment of HPV Associated Anogenital Pathology in Female Patients and Female Partners of Patients With Confirmed HPV Associated Oropharyngeal Carcinoma, PAP-OP Study
This study evaluates how often women with throat (oropharyngeal) cancer or who have a partner with oropharyngeal cancer get anogenital infections with high risk, potentially cancer-causing types of human papilloma virus (HPV).
- Trial name
- NCT06115772
- Testing
- Non-Interventional Study
- Where
- United States
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Cervical Carcinoma, Human Papillomavirus Infection
Self-collection for HPV Testing to Improve Cervical Cancer Prevention (SHIP) Trial (LMI-001-A-S04)
This clinical trial evaluates the use of self-collected vaginal samples for human papillomavirus (HPV) testing in patients referred for a colposcopy and/or cervical excisional procedures to improve cervical cancer prevention.
- Trial name
- NCT07281430
- Testing
- Biospecimen Collection, Cervical Biopsy, Colposcopy
- Where
- 18 sites in United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Vaccination Refusal, Opinions
Children Vaccination From 11 to 14 Years Old
The human papilloma virus infection is the most frequent sexually transmitted infection around the world. In the vast majority of cases, these are inapparent infections that disappear spontaneously.
- Trial name
- QUALIOPIVAC (NCT04871243)
- Testing
- Qualitative Interview
- Where
- France
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Eure-Seine
Cervical Intraepithelial Neoplasia Grade 2/3, Human Papilloma Virus Infection Type 16
PVX4 for the Treatment of Human Papilloma Virus (HPV)16+ Cervical Dysplasia
The purpose of this Phase 2 study is to compare the effects of administering the PVX4 combination device biologic product (pBI-4 DNA vaccine via electroporation-mediated intramuscular delivery with the TriGrid™ Delivery System)…
- Trial name
- NCT07454915
- Testing
- PVX4 Combination Product
- Where
- 10 sites in United States, Taiwan
- Volunteers
- 138 people
- Sponsor
- PapiVax Biotech, Inc.
Human Papilloma Virus Infection, Carcinoma in Situ of Uterine Cervix
Community-Driven Cervical Cancer Prevention in Western Kenya
There are many challenges to implementation of cervical cancer prevention in resource-limited countries, despite evidence based screening and treatment strategies.
- Trial name
- NCT02124252
- Testing
- Community-based testing with standard linkage to care, Community-based HPV testing with enhanced linkage to care
- Where
- Kenya
- Volunteers
- 7,200 people, healthy volunteers welcome
- Sponsor
- Duke University
HIV Infections
Examining the Incidence of Oral Human Papillomavirus (HPV) Shedding and Oral Warts After Beginning HAART in HIV-Infected Adults
Oral human papillomavirus (HPV) and oral warts are common health concerns for HIV-infected people. This study will examine the frequency of oral HPV DNA shedding and oral warts in HIV-infected people who are enrolled in ACTG…
- Trial name
- NCT01029249
- Where
- 35 sites in United States, Puerto Rico
- Volunteers
- 500 people
- Sponsor
- Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections
Chronic Kidney Disease
Antibody Response to Human Papillomavirus Recombinant Vaccine (Gardasil®) in Girls and Young Women With Chronic Kidney Disease
People with chronic kidney disease are known to have immune response abnormalities, including a diminished response to some vaccinations.
- Trial name
- NCT00806676
- Testing
- Gardasil® Vaccine (FDA-approved vaccination regimen)
- Where
- 2 sites in United States
- Volunteers
- 67 people
- Sponsor
- Johns Hopkins University
Human Papilloma Virus Infection, Stage III Squamous Cell Carcinoma of the Hypopharynx
Paclitaxel and Carboplatin Before Radiation Therapy With Paclitaxel in Treating HPV-Positive Patients With Stage III-IV Oropharynx, Hypopharynx, or Larynx Cancer
This phase II trial studies how well paclitaxel and carboplatin before radiation therapy with paclitaxel works in treating human papillomavirus (HPV)-positive patients with stage III-IV oropharynx, hypopharynx, or larynx cancer.
- Conditions
- Human Papilloma Virus Infection, Stage III Squamous Cell Carcinoma of the Hypopharynx, Stage III Squamous Cell Carcinoma of the Larynx, Stage III Squamous Cell Carcinoma of the Oropharynx
- Trial name
- NCT02048020
- Testing
- paclitaxel, carboplatin, intensity-modulated radiation therapy
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Jonsson Comprehensive Cancer Center
Condylomata Acuminata
Safety and Immunogenicity Study of the Recombinant Human Papillomavirus Virus Type 6/11 Bivalent Vaccine
This phase I clinical study was designed to evaluate the safety and immunogenicity of the novel recombinant HPV type 6/11 bivalent vaccine, manufactured by Xiamen Innovax Biotech CO., LTD., in healthy volunteers aged over 18-55…
- Trial name
- NCT02405520
- Testing
- low dosage HPV Vaccine, medium dosage HPV Vaccine, high dosage HPV Vaccine
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Jun Zhang
Cervical Cancer, Low-grade Squamous Intraepithelial Lesion,
A Multi-center Survey of HPV in Cervical Intraepithelial Neoplasia (CIN) With Longitudinal Follow-up of LSIL Cases
The aims of this study are: 1. Surveillance of the prevalence of HPV infection in ASCUS, AGCUS and SIL cases pooled from medical centers in Taiwan and analysis of the related epidemiological factors. 2.
- Conditions
- Cervical Cancer, Low-grade Squamous Intraepithelial Lesion,, Human Papillomavirus
- Trial name
- NCT00201370
- Where
- 4 sites in Taiwan
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- National Health Research Institutes, Taiwan
Human Papillomavirus, High-Grade Squamous Intraepithelial Lesions
Safety and Efficacy Study of TVGV-1 Vaccine to Treat HPV Induced Cervical HSIL
The purpose of this research study is to test the safety and effectiveness of the investigational study vaccine, called TVGV-1. The study will test the vaccine in women with high grade HPV cervical infection.
- Trial name
- NCT02576561
- Testing
- TVGV-1, GPI-0100
- Where
- 11 sites in United States
- Volunteers
- 10 people
- Sponsor
- THEVAX Genetics Vaccine
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