Clinical trials: Paracetamol Administration
Pain
Antagonistic Interaction CB1-paracetamol
Evaluation of an possible inhibiting effect of Rimonabant on the analgesic effect of Paracetamol in healthy volunteers
- Trial name
- NCT00750347
- Where
- 2 sites in France
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Hepatitis
To Evaluate the Efficacy and Safety of TYNADOTE® in the Treatment of Acetaminophen Overdose
To evaluate the efficacy and safety of TYNADOTE® in the treatment of acetaminophen overdose
- Trial name
- NCT05557448
- Testing
- TYNADOTE
- Where
- Taiwan
- Volunteers
- 24 people
- Sponsor
- Sinew Pharma Inc.
Migraine
Cefalium® Compared to Tylenol® in the Treatment of Migraine Attacks
National clinical trials, phase III, randomized, open, parallel, study of superiority, in which three hundred thirty-six (336) participants of both sexes, aged between 18 and 65 years will be randomly allocated to one of two…
- Trial name
- NCT02582996
- Testing
- Acetaminophen+Caffeine+Dihydroergotamine+Metoclopramide., Acetaminophen
- Where
- 6 sites in Brazil
- Volunteers
- 336 people
- Sponsor
- Ache Laboratorios Farmaceuticos S.A.
Primary Headache
Dexamethasone Plus Metoclopramide Versus Paracetamol/NSAIDs for Primary Headache
Primary headache disorders are among the most common neurological conditions presenting to emergency departments and can significantly impair quality of life and daily functioning.
- Trial name
- DMPH (NCT07605065)
- Testing
- Dexamethasone Plus Metoclopramide, Paracetamol/NSAIDs
- Volunteers
- 94 people
- Sponsor
- Pak Emirates Military Hospital
Knee Osteoarthritis
Effects Of Native Collagen Type 2 Treatment
The aim of this study was to evaluate symptomatic efficacy of native collagen type 2 on joint pain and function and its effects on urinary biological markers related to cartilage degeneration in patients with knee osteoarthritis.
- Trial name
- NCT02237989
- Testing
- paracetamol, paracetamol+native collagen type 2
- Volunteers
- 39 people
- Sponsor
- Eskisehir Osmangazi University
Osteoarthritis, Back Pain
A Study to Compare Oxycodone/Naloxone Prolonged Release Against Codeine/Paracetamol in the Treatment of Moderate to Severe Chronic Low Back Pain or Pain Due to Osteoarthritis
The purpose of this study is to compare oxycodone/naloxone combination tablet and codeine/paracetamol tablets in the treatment of moderate to severe chronic low back pain or pain due to osteoarthritis.
- Trial name
- NCT00784810
- Testing
- Oxycodone/Naloxone, Codeine/Paracetamol
- Where
- United Kingdom
- Volunteers
- 247 people
- Sponsor
- Napp Pharmaceuticals Limited
Migraine, Head Pain
A Study Comparing the Effectiveness and Safety of ULTRACET® (Tramadol HCl/Acetaminophen) Versus Placebo for the Treatment of Acute Pain From a Migraine Headache
The purpose of this study is to evaluate the effectiveness and safety of tramadol HCl/acetaminophen as a pain medication compared with placebo in the treatment of acute pain from a migraine headache.
- Conditions
- Migraine, Head Pain, Headache
- Trial name
- NCT00297375
- Testing
- tramadol HCl/acetaminophen
- Volunteers
- 375 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Common Cold, Flu-like Syndrome
Efficacy and Safety Assessment of an Anti-Cold Preparation in the Symptomatic Treatment of Common Cold and Flu-Like Syndrome
The aim of this study is to assess the efficacy and safety of an anti-cold preparation compounded by acetaminophen, chlorpheniramine and phenylephrine for the treatment of cold and flu symptoms in healthy individuals in a…
- Trial name
- NCT00940836
- Testing
- Resfenol, Co interventional acetaminophen
- Where
- Brazil
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Healthy
A Comparative Bioavailability/Food Effect Study of Immediate-Release and Extended-Release Tramadol HCl/Acetaminophen Combination Products Following Single-Dose and Multiple-Dose Administration in Healthy Adult Volunteers
The objectives of this two-part study were to compare the single-dose and multiple-dose pharmacokinetics of extended release and immediate-release fixed combination formulations containing tramadol-HCl/acetaminophen and to…
- Trial name
- NCT00973232
- Testing
- DDS-06C (650 mg acetaminophen and 75 mg tramadol HCl), DDS-06C (650 mg acetaminophen and 75 mg tramadol), Zaldiar®
- Where
- United Kingdom
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Labopharm Inc.
Cancer, Pain
Switching From Morphine to Oral Methadone Plus Acetaminophen in the Treatment of Cancer Pain
The purpose of this study is to determine whether oral methadone plus acetaminophen can substitute morphine in the treatment of cancer pain.
- Conditions
- Cancer, Pain, Palliative Care
- Trial name
- NCT00525967
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Faculdade de Medicina do ABC
Acute Pain
IV Acetaminophen as an Analgesic Adjunct
To determine the efficacy of intravenous (IV) acetaminophen as an analgesic adjunct to IV hydromorphone in the treatment of acute severe pain in the elderly Emergency Department (ED) patients.
- Trial name
- NCT02621619
- Testing
- IV acetaminophen + 0.5 mg IV hydromorphone, Normal saline + 0.5 mg IV hydromorphone
- Where
- United States
- Volunteers
- 159 people
- Sponsor
- Montefiore Medical Center
Analgesic, Enhanced Recovery After Surgery
Acetaminophen Before Surgery Lowers Postop Pain in Pediatric Solid Tumor Patients (ERAS)
Pain is the predominant subjective symptom experienced during the perioperative period in pediatric patients with solid tumors. Intense pain may impede early postoperative activities and delay the recovery process.
- Conditions
- Analgesic, Enhanced Recovery After Surgery, Postoperative Pain, Acetaminophen
- Trial name
- NCT07095816
- Testing
- Acetaminophen, Sterilized water
- Where
- China
- Volunteers
- 182 people
- Sponsor
- Nanjing Children's Hospital
Mental Disorders
Comparison of Drugs on Headache Treatment After ECT Treatment
Electroconvulsive treatment (ECT) is still actual for treatment of psychiatric symptoms. Headache is a very common symptom after this application.
- Trial name
- NCT03830398
- Testing
- Paracetamol, Deksketoprofen trometamol
- Where
- Turkey (Türkiye)
- Volunteers
- 225 people
- Sponsor
- Mustafa Kemal University
Pharmacokinetics, Magnetic Resonance Imaging
Oral Pharmacokinetics of Sulfasalazine, Paracetamol, Fexofenadine and Valsartan Using Different Administration Mediums
The purpose of this study is to determine pharmacokinetics of the probe-drugs sulfasalazine, given in 240 ml non-caloric water and paracetamol, fexofenadine and valsartan after oral administration, given in 240 ml non-caloric…
- Conditions
- Pharmacokinetics, Magnetic Resonance Imaging, Administration, Oral
- Trial name
- NCT03012763
- Testing
- Paracetamol, Sulfasalazine, Fexofenadine
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University Medicine Greifswald
Patent Ductus Arteriosus
Paracetamol Versus Ibuprofen for PDA Closure
Comparison between the safety and efficacy of oral paracetamol and oral ibuprofen in treatment of Patent Ductus Arteriosus (PDA) in premature infants
- Trial name
- NCT03265782
- Testing
- ibuprofen, paracetamol
- Volunteers
- 30 people
- Sponsor
- Ain Shams University
Malaria, Falciparum
The Effect of Paracetamol in the Treatment of Non-severe Malaria in Children in Guinea-Bissau
The National Malaria Programme in Guinea-Bissau recommends paracetamol for all children treated for malaria. We, the investigators of the Bandim Health Project, want to evaluate whether this treatment has any effect on: the…
- Trial name
- NCT00137566
- Testing
- acetaminophen (paracetamol)
- Where
- Guinea-Bissau
- Sponsor
- Bandim Health Project
Pain, Postoperative, Tonsillar Hypertrophy
Management of Post-Tonsillectomy Pain in Pediatric Patients
Single-center, randomized, open-label, non-inferiority treatment pilot study to evaluate the effectiveness of a combined acetaminophen and ibuprofen regimen for treatment of post-operative tonsillectomy pain in the pediatric…
- Conditions
- Pain, Postoperative, Tonsillar Hypertrophy, Tonsillitis
- Trial name
- NCT04551196
- Testing
- Alternating Acetaminophen and Ibuprofen, Combined Acetaminophen and Ibuprofen
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Washington University School of Medicine
Acute Pain Due to Trauma
NSAIDs Versus Paracetamol Versus Paracetamol + NSAIDs in Traumatic Pain Management
The purpose of this study is to: Compare the effect of paracetamol alone against NSAIDs alone against the association of paracetamol + NSAIDs in the treatment of traumatic pain.
- Trial name
- NCT03222518
- Testing
- Paracetamol, NSAID, paracetamol-NSAID
- Where
- Tunisia
- Volunteers
- 1,500 people
- Sponsor
- University of Monastir
Acute Liver Failure, Acute Liver Injury
Safety Study of Ornithine Phenylacetate to Treat Patients With Acute Liver Failure/Severe Acute Liver Injury
This Phase 2a clinical study is designed to provide data on OCR-002 in patients with acute liver failure/acute liver injury (ALF/ALI) in regard to: safety and tolerability; metabolism of the compound to glutamine and…
- Trial name
- STOP-ALF (NCT01548690)
- Testing
- Ornithine Phenylacetate
- Where
- 11 sites in United States
- Volunteers
- 47 people
- Sponsor
- William Lee
Pain
Assessment of the Pharmacokinetics of a Sustained Release Formulation of a Tramadol/Acetaminophen Combination
1. Objective: To evaluate the pharmacokinetic profiles of an SR 75 mg tramadol/650 mg acetaminophen formulation compared with an immediate release (IR) 37.5 mg tramadol/325 mg acetaminophen formulation after a single dose and at…
- Trial name
- NCT01880125
- Testing
- Tramadol HCI/Acetaminophen
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Yungjin Pharm. Co., Ltd.