Clinical trials: Paralysis; Stroke
Hemiplegia
The Relationship Of Ultrasonographic Measurements With Sarcopenia in Stroke
introduction:The aim of this study was to show the relationship of distal femoral cartilage and quadriceps thicknesses with functional status and presence of sarcopenia in ambulatory stroke patients with voluntary movement.
- Trial name
- NCT06254573
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Kayseri City Hospital
Amyotrophic Lateral Sclerosis, Stroke
Telehealth Implementation of Brain-Computer Interface
Determine if Telehealth intervention can allow/empower a caregiver (who is untrained) to effectively implement and utilize a Brain-Computer Interface for communication with a participant who is "Locked in" following progression…
- Trial name
- NCT05951556
- Testing
- Use of BCI
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Shirley Ryan AbilityLab
Ischaemic Stroke, Cerebral Infarction
Pilot Investigation of Stem Cells in Stroke Phase II Efficacy
The primary aim of this Phase II trial is to determine whether it is sufficiently likely that CTX DP treatment at a dose level of 20 million cells improves the recovery in the use of the paretic arm in acute stroke patients to…
- Conditions
- Ischaemic Stroke, Cerebral Infarction, Hemiparesis, Arm Paralysis
- Trial name
- PISCES-II (NCT02117635)
- Testing
- CTX DP
- Where
- 9 sites in United Kingdom
- Volunteers
- 23 people
- Sponsor
- ReNeuron Limited
Stroke, Spinal Cord Injuries
Grasping Rehabilitation With Functional Electrical Stimulation Garment
This study tests the feasibility, safety and efficacy of garments embedding conductive electrodes (FES-shirt) for the independent delivery of functional electrical stimulation (FES).
- Trial name
- GarmentGrasp (NCT03658798)
- Testing
- Functional Electrical Stimulation
- Where
- Canada
- Volunteers
- 8 people
- Sponsor
- Milos Popovic
Stroke
Efficacy of Robot-Assisted Rehabilitation of Hand Paralysis After Stroke
Among robotic devices, Gloreha, with its compliant mechanical transmission, may represent an easily applied innovative solution to rehabilitation, because the hand can perform grasp and release activities wearing the device by…
- Trial name
- NCT02711787
- Testing
- Experimental group, Control group, traditional rehabilitation
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Stroke
Neuromuscular Electrical Stimulation and Voluntary Muscle Contraction in Chronic Hemiplegic Stroke Patients
This single-blinded randomized controlled trial will be conducted at the Physical Therapy Department of the University of Lahore Teaching Hospital after approval from the Institute Research Ethics Board.
- Trial name
- NCT07458750
- Testing
- Conventional physiotherapy, Neuromuscular electrical stimulation and voluntary muscle contraction
- Where
- Pakistan
- Volunteers
- 25 people
- Sponsor
- University of Lahore
Stroke, Shoulder Disease
Comparison of the Effectiveness of TENS and TENS + NMES Treatment in Stroke Patients With Shoulder Pain
In this study, the effects of Transcutaneous Electrical Nerve Stimulation (TENS) and Neuromuscular Electrical Stimulation (TENS + NMES) applied in addition to TENS on pain, shoulder joint range of motion and upper extremity…
- Conditions
- Stroke, Shoulder Disease, Hemiplegia, Hemiplegic Shoulder Pain
- Trial name
- TENS (NCT07353190)
- Testing
- TENS, NMES
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Medical Park Bursa Hospital
Stroke, Stroke, Acute
Safety Evaluation of the ReWalk ReStore Device in Subjects With Mobility Impairments Due to Stroke
A multi-site, interventional, non-comparative, single-arm trial to evaluate the safety of the ReWalk ReStore device in subjects with hemiplegia/hemiparesis due to ischemic or hemorrhagic stroke.
- Conditions
- Stroke, Stroke, Acute, Stroke Hemorrhagic, Hemiparesis
- Trial name
- NCT03499210
- Testing
- ReWalk ReStore device
- Where
- 5 sites in United States
- Volunteers
- 40 people
- Sponsor
- ReWalk Robotics, Inc.
Perinatal Stroke, Hemiplegic Cerebral Palsy
Stimulation for Perinatal Stroke Optimizing Recovery Trajectories
Perinatal stroke causes lifelong neurological disability and most hemiparetic cerebral palsy (CP). With morbidity spanning diverse aspects of a child's life and lasting for decades, global impact is large, including 10000…
- Trial name
- SPORT (NCT03216837)
- Testing
- Cathodal transcranial direct current stimulation
- Where
- Canada
- Volunteers
- 89 people
- Sponsor
- University of Calgary
Stroke, Hemiplegia
Visual and Auditory Electromyography Biofeedback Among Stroke Patients
Stroke commonly results in impairments of balance, mobility, and lower extremity motor function that limit independence in daily activities.
- Conditions
- Stroke, Hemiplegia, Stroke Rehabilitation
- Trial name
- NCT07710937
- Testing
- Visual Electromyography Biofeedback, Auditory Electromyography Biofeedback, Conventional Physiotherapy
- Where
- Pakistan
- Volunteers
- 84 people
- Sponsor
- University of Lahore
Hemiparesis/Hemiplegia (One Sided Weakness/Paralysis)
Effects of Unilateral Robotic Assistance on Compensation Strategies and Muscular Activity During Hemiparetic Gait
Hemiparetic gait is characterized by strong asymmetries that could severely affect the quality of life of stroke survivors. This asymmetry is due to motor deficits in the paretic leg and the resulting compensations in the…
- Trial name
- NCT05138211
- Testing
- Exoskeleton assisted gait on a treadmill
- Where
- Spain
- Volunteers
- 10 people
- Sponsor
- Spanish National Research Council
Cerebral Palsy, Stroke
Reliability of the Melbourne Assessment
The aim of the study is to investigate the reliability of the Melbourne Assessment.
- Conditions
- Cerebral Palsy, Stroke, Traumatic Brain Injury, Meningomyelocele
- Trial name
- NCT02595411
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- University Children's Hospital, Zurich
Stroke, Spastic Hemiplegia
BTX-A and Mirror Therapy for Chronic Stroke Spasticity
Stroke is one of the leading causes of disability worldwide, particularly affecting the upper extremities and thus negatively impacting patients' activities of daily living and quality of life.
- Trial name
- NCT07331844
- Testing
- Botulinum toxin type A (Botox®, Allergan), Mirror Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Stroke, Autonomic Dysfunction
Repetitive Transcranial Magnetic Stimulation in Cardiac Autonomic Dysfunction
The aim of this study is to investigate the effects of repetitive transcranial magnetic stimulation (rTMS) added to conventional neurological rehabilitation on heart rate variability (HRV), quality of life, upper extremity muscle…
- Conditions
- Stroke, Autonomic Dysfunction, Hemiparesis
- Trial name
- NCT07482501
- Testing
- rTMS M1 Motor Cortex Protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Afyonkarahisar Health Sciences University
Stroke, Spastic Hemiplegia
Clinical and Ultrasonographic Evaluation of the Efficacy of Extracorporeal Shock Wave Therapy (ESWT) in Post-Stroke Spasticity
This research evaluate the effectiveness of Extracorporeal Shock Wave Therapy (ESWT) for treating spasticity in the wrist flexor muscles (flexor carpi ulnaris - FCU and flexor carpi radialis - FCR) of chronic stroke patients.
- Conditions
- Stroke, Spastic Hemiplegia, Extracorporal Shockwave Therapy (ESWT)
- Trial name
- NCT07119801
- Testing
- Radial Extracorporeal Shock Wave Therapy, Conventional rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Pamukkale University
Stroke, Upper Extremity Paresis
tDCS + CCFES-mediated Functional Task Practice for Post-stroke Upper Extremity Hemiplegia
After a stroke, it is very common to lose the ability to open the affected hand. Occupational and physical rehabilitation therapy (OT and PT) combined with non-invasive brain stimulation may help a person recover hand movement.
- Conditions
- Stroke, Upper Extremity Paresis, Hemiplegia
- Trial name
- NCT05866003
- Testing
- Active conventional tDCS montage plus CCFES, Active unconventional tDCS montage plus CCFES, CCFES with Occupational Therapy
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- MetroHealth Medical Center
Acute Stroke
Robot Assisted Upper Limb Neuro-Rehabilitation
Our long term objectives are to understand the mechanisms of motor impairment following neurologic injury and to develop interventions to improve motor recovery.
- Trial name
- NCT00011583
- Testing
- Robot-assisted therapy, Traditional therapy
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- US Department of Veterans Affairs
Chronic Stroke, Hemiplegia
Implementing Technology Enhanced Real Time Action Observation Therapy in Persons With Chronic Stroke
This is a feasibility study to alter the Microsoft Kinect software to be used as a rehabilitation tool. The prototype used is still in the early developing stage.
- Conditions
- Chronic Stroke, Hemiplegia, Hemiparesis, Paralysis
- Trial name
- TERTAOT (NCT03780296)
- Testing
- Real-time action observation with augmented Kinect
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Michigan
Hemiplegia
Periscapular Muscle Activation During Open and Closed Kinetic Chain in Stroke
The goal of this observational study is to compare the activity levels of the periscapular (levator scapula, serratus anterior, infraspinatus, upper, middle and lower trapezius) muscles during open and closed kinetic chain…
- Trial name
- NCT05990413
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Stroke, Spinal Cord Injuries (Complete and Incomplete)
Exoskeleton-assisted Neurorehabilitation
Objective assesment of the feasibility of integrating the Ekso Bionics - Ekso NR device into outpatient care Objective assesment of quality of life, functionality and clinical symptomps of patients with stroke, cerebellar ataxia…
- Conditions
- Stroke, Spinal Cord Injuries (Complete and Incomplete), Cerebellar Ataxia, Spastic Paraplegia
- Trial name
- NCT07352085
- Testing
- Gait training with exoskeleton
- Where
- Hungary
- Volunteers
- 5 people
- Sponsor
- Somogy Megyei Kaposi Mór Teaching Hospital