Clinical trials: Paranoid Delusions
Paranoid Schizophrenia, Schizophrenia and Related Disorders
Face Your Fears: Cognitive Behavioural Virtual Reality Therapy for "Paranoia".
The study is a randomised, assessor-blinded parallel-groups superiority clinical trial fulfilling the CONSORT criteria for non-pharmacological treatment.
- Conditions
- Paranoid Schizophrenia, Schizophrenia and Related Disorders, Schizophrenia Prodromal, Schizotypal Disorder
- Trial name
- FYF (NCT04902066)
- Testing
- Cognitive Behavioural Virtual Reality Therapy., Traditional Cognitive Behavioural Therapy
- Where
- Denmark
- Volunteers
- 259 people
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Schizophrenia, Schizoaffective Disorder
Trial of Cognitive Behavioral Therapy for Schizophrenia
The following study addresses the hypothesis that cognitive-behavioral interventions will be effective in reducing positive and negative symptoms of schizophrenia under the conditions of the German health care system.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Delusional Disorder
- Trial name
- NCT00300651
- Testing
- Cognitive Behavioral Therapy
- Where
- Germany
- Volunteers
- 70 people
- Sponsor
- Philipps University Marburg
Schizophrenia, Schizoaffective Disorder
Schizophrenic Patients Taking Part in Integrated Care Program
Purpose of this non-interventional study (NIS) is to assess the effect of the participation in an integrated care program on treatment outcomes in patients treated with Seroquel for schizophrenia.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Schizophreni-form Disorder, Delusional Disorder
- Trial name
- CARE I (NCT00617214)
- Where
- 14 sites in Germany
- Volunteers
- 20 people
- Sponsor
- AstraZeneca
Psychotic Disorders, Schizophrenia
Development and Pilot Evaluation of Modified Cognitive Behavioural Therapy for Adolescents With Early Onset Psychosis
In the last decade cognitive behavioural therapy (CBT) approaches for patients with schizophrenia have been developed, which where especially designed to reduce severity of positive symptoms, readmission rates, treatment…
- Conditions
- Psychotic Disorders, Schizophrenia, Schizoaffective Disorder, Delusional Disorder
- Trial name
- mCBT (NCT00465920)
- Testing
- modified cognitive behavioural therapy (mCBT)
- Where
- Germany
- Volunteers
- 42 people
- Sponsor
- University of Cologne
Schizophrenia, Schizoaffective Disorder
Schizophrenia, Antipsychotic Treatment and the Risk for Diabetes Mellitus
This preliminary study aims to investigate the mechanism of higher rates of type 2 diabetes mellitus in patients with schizophrenia.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Delusional Disorder
- Trial name
- NCT00222807
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Psychotic Disorders, Schizophrenia
Effect of Individual Cognitive Stimulation at Home in Adults With Psychotic Disorders
The aim of this study is to test the effect of cognitive stimulation (CS), applied individually and at home, on the overall cognitive functioning, emotional state, functionality, and quality of life (QoL) in adults with psychotic…
- Conditions
- Psychotic Disorders, Schizophrenia, Schizoaffective Disorder, Delusional Disorder
- Trial name
- NCT04783285
- Testing
- Individual cognitive stimulation therapy (iCST)
- Where
- Portugal
- Volunteers
- 38 people
- Sponsor
- CEDIARA - Assoc. Solidariedade Social de Ribeira de Fráguas
Schizophrenia Disorders
Volatility in Paranoia (VIP) Trial: An RCT of Changes in Volatility With Psychotherapy
The goal of this clinical trial is to learn whether learning and belief updating change in response to the treatment of persecutory delusions, in individuals with schizophrenia-spectrum disorders. The main questions are: 1.
- Trial name
- VIP (NCT06835556)
- Testing
- Cognitive Behavioral Therapy, TAU
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Vanderbilt University Medical Center
Schizophrenia, Delusional Disorders (ICD-10)
Cognitive Determinants of Psychoeducation and Information in Psychoses
The aim of the study is to examine whether the efficacy of psychoeducation in patients with schizophrenia or schizoaffective disorders is dependent on their cognitive performance level and if a preceding cognitive training can…
- Trial name
- COGPIP (NCT00646256)
- Testing
- COGPACK training, psychoeducation
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- German Research Foundation
Schizophrenia, Delusional Disorder
Acceptance and Commitment Therapy for Delusions
Symptoms of schizophrenia have historically been treatment resistant despite advances in psychopharmacology. Acceptance and Commitment Therapy (ACT) has been shown through some preliminary research to be effective with psychotic…
- Trial name
- ACT (NCT00657631)
- Testing
- Acceptance and Commitment Therapy
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Weill Medical College of Cornell University
Paranoid Delusions
Cognitive Behavioral Therapy for Paranoia in Schizophrenia
The main objective of this study is to determine the preliminary efficacy of Paranoia-Focused Cognitive Behavioral Therapy (PFCBT) relative to standard care in the treatment of persecutory delusions in patients diagnosed with…
- Trial name
- CBTp (NCT01704833)
- Testing
- Paranoia-Focused Cognitive Behavioral Therapy (PFCBT)
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Weill Medical College of Cornell University
Delusional Disorder, Brief Psychotic Disorder
FEEL-GOOD: A Multicenter Trial of a Mindfulness-Based Group Therapy in Young Adults With Early Psychosis
FEEL-GOOD is a prospective multi-site single-blinded randomized controlled trial in young inpatients with acute early psychosis. Participants are randomized 1:1 to FEEL-GOOD plus treatment as usual (TAU) or TAU alone.
- Conditions
- Delusional Disorder, Brief Psychotic Disorder, Schizophreniform Disorder, Schizophrenia / Schizoaffective Disorder
- Trial name
- FEEL-GOOD (NCT07645443)
- Testing
- FEEL GOOD, Treatment as Usual (TAU)
- Where
- 8 sites in Germany
- Volunteers
- 252 people
- Sponsor
- Stephanie Mehl
Schizophrenia Spectrum and Other Psychotic Disorders, Schizophrenia
Biomarkers/Biotypes, Course of Early Psychosis and Specialty Services
The Biomarkers/Biotypes, Course of Early Psychosis and Specialty Services (BICEPS) study aims to understand the early stages of psychotic disorders like Schizophrenia, Schizoaffective Disorder, and Bipolar I Disorder.
- Conditions
- Schizophrenia Spectrum and Other Psychotic Disorders, Schizophrenia, Delusional Disorder, Bipolar 1 Disorder
- Trial name
- BICEPS (NCT06740383)
- Where
- 6 sites in United States
- Volunteers
- 320 people
- Sponsor
- Beth Israel Deaconess Medical Center
Schizophrenia, Schizoaffective Disorder
Agomelatine Treatment of Depression in Schizophrenia (AGOPSYCH)
Major depressive episodes (MDEs) occur frequently during the course of psychotic disorders, and several antidepressive agents have been successfully applied.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Delusional Disorder
- Trial name
- AGOPSYCH (NCT01822418)
- Testing
- agomelatine
- Where
- Germany
- Volunteers
- 27 people
- Sponsor
- Central Institute of Mental Health, Mannheim
Schizophrenia, Schizoaffective Disorder
SUCCEED Africa: Support, Comprehensive Care and Empowerment of People With Psychosocial Disabilities
Although psychotic disorders typically affect less than 1% of the population, they are a significant cause of disability worldwide.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Schizotypal Disorder, Acute and Transient Psychotic Disorder
- Trial name
- SUCCEED (NCT06007105)
- Testing
- SUCCEED Community-Based Intervention
- Where
- 4 sites in Malawi, Nigeria and 2 more
- Volunteers
- 425 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Schizophrenia; Psychosis, Persecutory Delusion
Cognitive Behavioral Therapy (CBT) Study Evaluating the Updating of Persecutory Beliefs
The purpose of this study is to examine how Bayesian belief updating changes throughout psychotherapeutic treatment for persecutory delusions.
- Trial name
- NCT04748679
- Testing
- Worry Intervention, Befriending
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Vanderbilt University Medical Center
Dementia
Treating Behavioral Disturbances in Individuals With Dementia
This study will compare the safety and effectiveness two medications, citalopram (Celexa®) and risperidone (Risperdal®).
- Trial name
- NCT00073658
- Testing
- Citalopram, Risperidone
- Where
- United States
- Volunteers
- 137 people
- Sponsor
- University of Pittsburgh
Schizophrenia, Schizotypal and Delusional Disorders
The Efficacy of Using a Smartphone App to Support Shared Decision Making in People With a Diagnosis of Schizophrenia
This study investigates the effects of using a smartphone app to support shared decision making (SDM) for people with schizophrenia-spectrum disorders in an outpatient treatment setting.
- Trial name
- NCT03554655
- Testing
- Momentum app
- Where
- 7 sites in Denmark
- Volunteers
- 194 people
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Late Onset Schizophrenia, Delusional Disorder (Late Onset)
Tau Biomarkers in Late-onset Psychosis (LOP)
Hallucinations or delusions that occur for the first time in older people with no acute medical problems or mood symptoms may be related to impending dementia.
- Trial name
- NCT06336382
- Testing
- Tau PET imaging scan
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Jeremy Koppel
Schizophrenia, Schizoaffective Disorder
Multi-disciplinary Treatment for Patients Experiencing First Episode of Psychosis
This study will assess the effectiveness of an experimental treatment intervention for adolescents and adults who have experienced their first episode of psychosis during the past two years.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Schizophreniform Disorder, Delusional Disorder
- Trial name
- NCT01216891
- Testing
- Multi-element, team-oriented treatment
- Where
- 2 sites in United States
- Volunteers
- 65 people
- Sponsor
- Research Foundation for Mental Hygiene, Inc.
Supported Accommodation Residents, Schizophrenia, Shizotypal and Delusional Disorders
Quantitative Investigation of Environment and Participation
Supported accommodation provides individuals with complex mental health difficulties the opportunity to maintain a tenancy with different levels of staff support provided to develop and maintain living skills and engage in social…
- Conditions
- Supported Accommodation Residents, Schizophrenia, Shizotypal and Delusional Disorders, Mood Affective Disorders, Disorders of Adult Personality and Behavior
- Trial name
- QIEP (NCT04106960)
- Testing
- No Intevention Used
- Where
- United Kingdom
- Volunteers
- 235 people
- Sponsor
- Queen Margaret University