Clinical trials: Parkinson
Gastric Adenocarcinoma, Gastroesophageal Junction Adenocarcinoma
A Study of Pembrolizumab (MK-3475) in Participants With Recurrent or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma (MK-3475-059/KEYNOTE-059)
This is a study of pembrolizumab (MK-3475) for advanced gastric or gastroesophageal junction adenocarcinoma; pembrolizumab will be given as monotherapy to participants who have had previous treatment or who are treatment-naïve…
- Trial name
- NCT02335411
- Testing
- pembrolizumab, cisplatin, 5-FU
- Volunteers
- 318 people
- Sponsor
- Merck Sharp & Dohme LLC
Parkinson Disease
Exploration of the Mechanism of Movement Improvement During RBD in Parkinson's Disease Using NIRS
The purpose of this study is to confirm the improvement of movement during RBD in Parkinson's disease and to explore the neuronal network involved in this improvement using NIRS.
- Trial name
- NIRS-RBD (NCT03060239)
- Testing
- Near Infrared Spectroscopy
- Where
- France
- Volunteers
- 13 people
- Sponsor
- Clinique Beau Soleil
Parkinson's Disease
A Study of AAV-hAADC-2 in Subjects With Parkinson's Disease
Safety Study in subjects with Parkinson's Disease
- Trial name
- NCT00229736
- Testing
- AAV-hAADC-2
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Genzyme, a Sanofi Company
Parkinson's Disease
Remote Ischemic Conditioning for Parkinson's Disease
The purpose is to evaluate feasibility and efficacy of Remote Ischemic Conditioning(RIC) as adjuvant therapy for Parkinson's Disease(PD).
- Trial name
- NCT04327687
- Testing
- Remote ischaemic conditioning, conventional therapy
- Where
- China
- Volunteers
- 50 people
- Sponsor
- General Hospital of Shenyang Military Region
Oropharyngeal Dysphagia (OPD), Parkinson
Results of Combined Medical and Swallowing Behavioral Readjustment Therapy in Oropharyngeal Dysphagia Management Among Parkinson's Patients
The study aims to assess the efficacy of using swallowing behavioral readjustment technique in combination with medical treatment in management of oropharyngeal dysphagia among Parkinson's patients in order to improve the…
- Conditions
- Oropharyngeal Dysphagia (OPD), Parkinson, Swallowing Difficulties
- Trial name
- NCT07618637
- Testing
- combined pharmaceutical treatment and rehabilitation techniques, pharmaceutical treatment only
- Where
- Egypt
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Tanta University
Parkinson's Disease
Crossover Versus Stabilometric Platform in Parkinson's Disease
The aims of this study is to assess the efficacy of the crossover on balance in Parkinsonian patients and compare this results with the results of a control group of patients treated with a stabilometric platform.
- Trial name
- PDvsCOPD (NCT02098577)
- Testing
- Crossover, Stabilometric Platform
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Ospedale Generale Di Zona Moriggia-Pelascini
Parkinson Disease
Repurposing Lithium for Parkinson's Disease: a RCT
This study will examine the effects of lithium 20mg/day compared to placebo on MRI and blood-based biomarkers among 20 early-stage Parkinson's disease patients.
- Trial name
- NCT06339034
- Testing
- Lithium
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- State University of New York at Buffalo
Parkinson Disease
Transcranial Direct Current Stimulation (tDCS) and Virtual Reality Task in Parkinson Disease
A double-blinded randomized controlled trial will be conducted, and all the participants will undertake one session of non-immersive VR tasks and tDCS-active or tDCS-sham. It will be a cross-sectional protocol.
- Trial name
- NCT04527809
- Testing
- tDCS-active
- Where
- Brazil
- Volunteers
- 54 people
- Sponsor
- University of Sao Paulo
Parkinson Disease, Attention Disturbances
Relationship Between Dopaminergic Asymmetric Degeneration and Attentional Resources in Parkinson's Disease.
The researchers aimed to investigate the relationship between the asymmetric dopaminergic degeneration and the attentional resources in a group of patients with Parkinson's disease (PD).
- Trial name
- RTsAsMIRT (NCT03476668)
- Testing
- MIRT
- Volunteers
- 100 people
- Sponsor
- Ospedale Generale Di Zona Moriggia-Pelascini
Arthritis, Asthma
Mobility Assessment in Multi-morbidity
Multimorbidity (the presence of two or more coexisting long-term conditions) is a significant challenge facing the NHS, especially given UK's ageing population and the association with high levels of illness burden and healthcare…
- Conditions
- Arthritis, Asthma, Atrial Fibrillation, Bronchiectasis
- Trial name
- Multi-mobility (NCT06473168)
- Volunteers
- 55 people
- Sponsor
- Northumbria University
Parkinson Disease, Idiopathic
A Novel Robotic System for Motor-cognitive Exercise for Patients With Parkinson's Disease
The objective of this study is to test a gamified rehabilitation system in a sitting position involving robots and music for the benefit of individuals with Parkinson's disease (PD).
- Trial name
- PD (NCT06730074)
- Testing
- Using a gamified rehabilitation system in a sitting position involving robots and music for the benefit of individuals with Parkinson's disease (PD)
- Where
- Israel
- Volunteers
- 15 people
- Sponsor
- Adi Negev-Nahalat Eran
Aging Disorder, Parkinson Disease
Contribution of Virtual Reality and Modelling in Falling Risk Assessment in Elderly and Parkinson's Disease Patients
The process of ageing affects at the same time the sensory, cognitive and driving functions. Furthermore, ageing is often accompanied by pathologies increasing the effects of the senescence.
- Trial name
- PrévSim (NCT03848897)
- Testing
- Metrology of motor behavior
- Where
- France
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Parkinson Disease, Neurodegenerative Diseases
Mobile Parkinson Observatory for Worldwide, Evidence-based Research (mPower)
The purpose of this study is to understand variation in the symptoms of Parkinson disease. This study uses an iPhone app to record these symptoms through questionnaires and sensors.
- Conditions
- Parkinson Disease, Neurodegenerative Diseases, Movement Disorders, Central Nervous System Diseases
- Trial name
- mPower (NCT02696603)
- Testing
- Participant self-assessment surveys, Phonation, Gait and balance
- Where
- United States
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Sage Bionetworks
Parkinson Disease
Parkinson's Disease in Home Rehabilitation Services
Introduction: Home rehabilitation is a form of care that is part of most health systems. Patients with Parkinson's disease can be referred to these Home Rehabilitation Services given the characteristics of the pathology they…
- Trial name
- NCT05340283
- Testing
- physiotherapy
- Volunteers
- 145 people
- Sponsor
- University of Oviedo
Parkinson's Disease
INfusion VErsus STimulation in Parkinson's Disease
Both Continuous intrajejunal Levodopa Infusion (CLI) and Deep Brain Stimulation (DBS) are accepted therapies for the treatment of advanced Parkinson's disease (PD). To date, no comparative studies have been executed.
- Trial name
- INVEST (NCT02480803)
- Testing
- Continuous intrajejunal infusion of levodopa-carbidopa, deep brain stimulation
- Where
- Netherlands
- Volunteers
- 51 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Parkinson's Disease, HIV Infections
Using Heavy Water to Study Cell Dynamics in Parkinson's Disease
This pilot study will assess the feasibility of using heavy water as a safe 'tracer' for biomarker studies of diseases of the brain and spinal cord, that, together, are also called the central nervous system (CNS).
- Trial name
- NCT00990379
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Salena Killion
Parkinson's Disease
Long-Term Safety Study of KW-6002 (Istradefylline) in Parkinson's Disease Patients
Patients with Parkinson's disease who completed the prior double-blind study 6002-009 are eligible to enter into this long-term study.
- Trial name
- 6002-010 (NCT00957203)
- Testing
- Istradefylline
- Where
- Japan
- Volunteers
- 308 people
- Sponsor
- Kyowa Kirin Co., Ltd.
Parkinson's Disease
Study to Assess the Safety and Effects of Autologous Adipose-Derived SVF Cells in Patients With Parkinson's Disease
The intent of this clinical study is to answer the questions: 1. Is the proposed treatment safe 2. Is treatment effective in improving the disease pathology of patients with Parkinson's Disease and clinical outcomes.
- Trial name
- NCT01453803
- Testing
- Harvesting and Implantation of Adipose-Derived Stem Cells
- Where
- United States
- Sponsor
- Ageless Regenerative Institute
Parkinson Disease
Chest PNF on Pulmonary Function in Parkinson Disease
Background: Parkinson disease (PD) is a progressive neurodegenerative disorder and characterized by tremor, rigidity and bradykinesia.
- Trial name
- NCT03977740
- Testing
- chest PNF, Conventional
- Where
- India
- Volunteers
- 20 people
- Sponsor
- Subhasish Chatterjee
Idiopathic Parkinson Disease, Parkinson's Disease and Parkinsonism
Adipose-derived Stromal Vascular Fraction Cells to Treat Parkinson
This is an interventional study to treat 10 patients with a diagnosis of Parkinson's disease with neurological assessment from the Oxford Parkinson's Disease Quotient-39 (PDQ-39) and Movement Disorders Society Universal…
- Trial name
- SVFP1 (NCT05699161)
- Testing
- Adipose-derived stromal vascular fraction cells
- Where
- Nicaragua
- Volunteers
- 10 people
- Sponsor
- Samuel Vilchez, PhD