Clinical trials: Parodontitis
Periodontitis
Tinder Fungus as an Adjunct to Non-surgical Periodontal Therapy for Periodontitis
The goal of this interventional clinical study is to learn if a Tinder fungus-based formulation -specifically a toothpaste and oral supplement powder-works as adjuncts to non-surgical periodontal therapy (NSPT) in patients with…
- Trial name
- NCT07482878
- Testing
- Tinder fungus-based formulation, Commercially available toothpaste
- Where
- Austria
- Volunteers
- 70 people
- Sponsor
- Sigmund Freud PrivatUniversitat
Periodontitis, Periodontitis Stage III
Alb-PRF as an Adjunct to Regenerative Periodontal Surgery
Periodontitis is characterized by the progressive destruction of tooth-supporting tissues and may lead to the formation of intrabony periodontal defects.
- Conditions
- Periodontitis, Periodontitis Stage III, Periodontal Intrabony Defects
- Trial name
- NCT07805317
- Testing
- Regenerative Periodontal Surgery With EDTA and Allogeneic Bone Graft, Albumin Platelet-Rich Fibrin
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Halil Ata BIÇAKÇIOĞLU
Periodontitis
Effects of Interdental Brush Dipped in 0.2% Hyaluronic Acid Gel on Periodontitis
This study aimed to compare the effects of using an interdental brush dipped in 0.2% HA gel with those of using a regular interdental brush on clinical periodontal parameters following SRP among patients with periodontitis.
- Trial name
- NCT06309797
- Testing
- Interdental brush+HA, Interdental brush
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Özlem SARAÇ ATAGÜN
Periodontitis, Periodontal Disease
Short Implants in Unitary Implant-supported Rehabilitations in the Posterior Maxilla and Mandible: 5 Years of Follow-up
Implant-supported rehabilitation of regions with severe bone resorption is a challenge for implant dentists. Structures such as the maxillary sinus and the inferior alveolar canal often make it impossible to use implants of…
- Trial name
- NCT07688408
- Testing
- bone loss
- Where
- Brazil
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Guarulhos
Periodontal Diseases
Evaluation of a Herbal Antiseptic Gel as a Supportive Treatment for Teeth Cleaning in Patients With Periodontal Disease
The goal of this clinical trial is to learn if the herbal gel is more effective as compared to placebo in reducing periodontal inflammation in patients with periodontal disease.
- Trial name
- NCT07135674
- Testing
- herbal drug
- Where
- India
- Volunteers
- 50 people
- Sponsor
- Rungta College of Dental Sciences and Research
Periodontitis
Injectable Platelet Rich Fibrin in Periodontal Treatment
The aim of this randomized controlled parallel clinical trial is to investigate the efficacy of injectable Platelet Rich Fibrin (iPRF) as an adjunctive to non-surgical periodontal therapy (STEP 1 \& 2 of periodontal treatment).
- Trial name
- I-PRF (NCT06814418)
- Testing
- Non-surgical periodontal treatment, Injectable Platelet Rich Fibrin (I-PRF)
- Where
- Greece
- Volunteers
- 32 people
- Sponsor
- Aristotle University Of Thessaloniki
Periodontitis, Adult, Periodontitis, Aggressive
Efficacy of Sub-gingival Air-polishing With Erythritol in the Treatment of Periodontitis
The first step in the management of periodontal disease involves the non-surgical removal of the soft and hard bacterial deposits at all supra- and sub-gingival sites, especially into deep pockets, which can be carried on with…
- Trial name
- GBT2017 (NCT04264624)
- Testing
- Perioflow and Erythritol powder and ultrasonic debridement, Airflow and Erythritol powder and ultrasonic debridement
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Periodontal Diseases
Association of Coffee With Periodontal Status
A total of 318 patients applying to Bolu Abant İzzet Baysal University will be included in the study. Based on anamnesis, radiographic examination, and the 2018 classification of periodontal diseases, the participants will be…
- Trial name
- acpc (NCT07166276)
- Testing
- coffee
- Where
- Turkey (Türkiye)
- Volunteers
- 318 people, healthy volunteers welcome
- Sponsor
- Tuğba ŞAHİN
Periodontitis, Diabetes
Prevalence of Periodontitis in Diabetic Patients of Egyptian Population
The study aims at determining the prevalence of Periodontitis in diabetic Egyptian dental outpatients attending the diagnostic centre at faculty of Dentistry, Cairo University
- Trial name
- NCT05322369
- Testing
- periodontal charting only
- Where
- Egypt
- Volunteers
- 447 people
- Sponsor
- Cairo University
Preterm Birth, Low Birthweight Neonate
Xylitol and the Prevention of Periodontal Disease and Preterm Birth Trial
The ground-breaking Prevention of Prematurity and Xylitol (PPaX) cluster randomized controlled clinical trial was conducted in Lilongwe, Malawi and enrolled approximately 10,069 pregnant individuals seeking to evaluate the impact…
- Conditions
- Preterm Birth, Low Birthweight Neonate, Periodontitis, Gingivitis
- Trial name
- XaPPP (NCT07424846)
- Testing
- Xylitol Chewing gum, Sorbitol chewing gum
- Where
- Malawi
- Volunteers
- 6,000 people
- Sponsor
- University of Washington
Periodontitis, Intrabony Periodontal Defect
Effectiveness of Hyaluronic Acid (hyaDENT BG® Gel) Compared With Enamel Matrix Proteins (Emdogain®) in the Treatment of Angular Bone Defects in Combination With a Xenograft (Bio-Oss Collagen®)
The goal of this clinical trial is to learn whether hyaluronic acid (HyaDent® BG) provides similar benefits to Emdogain® when both are used with Bio-Oss® Collagen during periodontal surgery in adults with periodontal (intrabony)…
- Conditions
- Periodontitis, Intrabony Periodontal Defect, Periodontal Bone Loss
- Trial name
- NCT07230522
- Testing
- Bio-Oss Collagen + HyaDent BG, Bio-Oss Collagen + Emdogain
- Where
- Bulgaria
- Volunteers
- 17 people
- Sponsor
- Medical University of Sofia
Presence of Periodontal Disease, Knowledge of Periodontal Disease
Knowledge of Periodontitis and Its Relation to Periodontal Health
This study aims to evaluate the level of knowledge regarding periodontal disease and its association with periodontal health status among health sciences students.
- Trial name
- NCT07405541
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Dentinal Hypersensitivity, Chronic Periodontitis
Efficacy of Herbal Dentifrice for Management of Dentinal Hypersensitivity
Recently, Herbal formulations have gained wide popularity in management of Dentinal hypersensitivity owing to the additive effects of active anti-inflammatory ingredients like Curcuma longa, Clove oil, Acacia arabica and Spinach…
- Trial name
- NCT05852366
- Testing
- Toothpaste Preparation
- Where
- India
- Volunteers
- 75 people
- Sponsor
- Dr. D. Y. Patil Dental College & Hospital
Periodontitis, Periodontal Diseases
The Influence of Local Antibiotic Therapy on the Outcomes Following Periodontal Regeneration Procedures.
Assessmnet of the influence of local antibiotic therapy on the clinical, radiological, microbiological parameters and the inflammation mediators levels in the gingival crevicular fluid (GCF) following periodontal regeneration…
- Trial name
- ANBperio (NCT07027137)
- Testing
- SRP+ANB+SURG, SRP+SURG
- Where
- Poland
- Volunteers
- 40 people
- Sponsor
- Medical University of Bialystok
Chronic Periodontitis
Adjunctive Photodynamic Therapy in Treatment of Chronic Periodontitis
The aim of this study is to verify the efficacy of Photodynamic Therapy (PDT) as an adjunct to non-surgical treatment of chronic periodontitis by assessing clinical and microbiological and immunological parameters.
- Trial name
- NCT01034501
- Testing
- photodynamic therapy
- Where
- Brazil
- Volunteers
- 38 people
- Sponsor
- University of Sao Paulo
Gingivitis, Periodontitis
Circadian Clock Gene Expression in Periodontal Disease
This observational study aims to investigate whether periodontal inflammation is associated with alterations in the expression of circadian clock-related genes and proteins in gingival tissues.
- Trial name
- PERIOCLOCK (NCT07452783)
- Testing
- Gingival Tissue Biopsy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Inonu University
Periodontitis
Use of Laser Assisted New Attachment Procedure and Low Level Laser Therapy for Periodontitis Patients
In this study, it is evaluated the effects of laser assisted new attachment procedure (LANAP) and low level laser therapy (LLLT) and on clinical, biochemical and radiographic parameters in addition to non-surgical periodontal…
- Trial name
- LANAP LLLT (NCT04694222)
- Testing
- Nd:YAG laser
- Where
- Turkey (Türkiye)
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Mouth Diseases, Periodontal Inflammation
Evaluation of Biomarkers Levels in Gingival Crevicular Fluid, Saliva and Serum for Different Periodontal Diseases
The aim of this study is; detection of interleukin(IL)-38, IL-36 gamma(γ) , IL-17 and matrix metalloproteinase(MMP)-9 levels in gingival crevicular fluid (GCF), saliva and serum samples of periodontally healthy, gingivitis and…
- Conditions
- Mouth Diseases, Periodontal Inflammation, Periodontal Diseases
- Trial name
- NCT05435131
- Testing
- GCF obtaining, Saliva Obtaining, Serum obtaining
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Parodontitis
Evaluation of the Efficacy of STERIFY GEL in the Treatment of Periodontitis Following Scaling and Root Planing
The purpose of this clinical study is to evaluate the safety and efficacy of treating periodontal disease with the STERIFY GEL medical device in combination with SRP procedure, in terms of periodontal pocket healing.
- Trial name
- SFYCT (NCT05975177)
- Testing
- Sterify Gel, Scaling and root planing
- Where
- Italy
- Volunteers
- 34 people
- Sponsor
- Sterify S.r.l.
Periodontitis, Cardiac Electrophysiology
Effects of Periodontitis on Heart Rate Variability
Periodontitis is a chronic inflammatory disease associated with systemic inflammatory burden and possible alterations in autonomic nervous system regulation.
- Trial name
- NCT07735312
- Testing
- Non-surgical periodontal therapy
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
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