Clinical trials: Paroxysmal AF
Atrial Fibrillation, Atrial Flutter
iCLAS™ Cryoablation System Post-Market Clinical Follow-up (PMCF) Study
A prospective, single-arm, multi-center study designed to collect real world safety and performance data of the Adagio Medical iCLAS Cryoablation System in the treatment of drug refractory, recurrent, symptomatic, Paroxysmal…
- Conditions
- Atrial Fibrillation, Atrial Flutter, Paroxysmal Atrial Fibrillation, Persistent Atrial Fibrillation
- Trial name
- NCT05416086
- Testing
- cryoablation procedure using the iCLAS Cryoablation System
- Where
- 4 sites in Belgium, Germany and 1 more
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Adagio Medical
Paroxysmal Atrial Fibrillation
Atrial Electromechanical Function in Endurance Athletes With and Without Atrial Fibrillation
This study evaluates cardiac structure and function differences between healthy endurance trained athletes with atrial fibrillation and healthy age matched endurance trained athletes without atrial fibrillation.
- Trial name
- NCT03305744
- Where
- Canada
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Atrial Fibrillation Paroxysmal
Prospective Validation Study of AI-based Prediction Algorithm for the Prediction of Paroxysmal Atrial Fibrillation
The purpose of this study is to predict the occurrence of paroxysmal atrial fibrillation by finding high-risk group from normal sinus rhythm ECG through artificial intelligence-based prediction algorithm.
- Trial name
- PROVISION-AF (NCT05725187)
- Testing
- MobiCare
- Where
- 11 sites in South Korea
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Ewha Womans University Mokdong Hospital
Paroxysmal Atrial Fibrillation
Cryoballoon PVI With PWI Versus PVI Alone In Patients With PAF
Cryoballoon ablation has emerged as a safe and effective strategy for treatment of atrial fibrillation (AF) for which it has recently received a 'first-line' therapy indication by the FDA.
- Trial name
- NCT05296824
- Testing
- Cryoballoon ablation for the treatment of atrial fibrillation
- Where
- 4 sites in United States
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Sacramento EP Research
Paroxysmal Atrial Fibrillation, Catheter Ablation
Contact Force Sensing and Pulmonary Vein Isolation
Introduction - Pulmonary vein isolation (PVI) is the cornerstone of paroxysmal atrial fibrillation (AF) ablation. Recurrences remain, however, not infrequent and are mainly due to PVs reconnection.
- Trial name
- NCT01630031
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Clinique Pasteur
Paroxysmal Atrial Fibrillation, Atrial Fibrillation
Adjunctive Ganglionated Plexus Ablation in Redo-Pulmonary Vein Isolation
The investigator propose to test the efficacy of adjunctive ET-GP ablation in patients undergoing redo PVI for paroxysmal AF.
- Trial name
- ADD-GP (NCT03535818)
- Testing
- Radiofrequency ablation
- Where
- United Kingdom
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Atrial Fibrillation
Use of Fish Oils to Reduce the Frequency and Duration of Episodes of Atrial Fibrillation in Patients With Paroxysmal Atrial Fibrillation.
The purpose of this study is to investigate whether fish oil supplements may reduce the frequency and duration of paroxysmal atrial fibrillation episodes.
- Trial name
- NCT00232245
- Testing
- Fish oil
- Where
- Australia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Melbourne Health
Paroxysmal Atrial Fibrillation, Catheter Ablation Strategies
Unexcitability Along the Ablation as an Endpoint for Atrial Fibrillation Ablation
to assess the near-term (12 months) efficacy of pulmonary vein isolation.
- Trial name
- NCT01724437
- Testing
- catheter based pulmonary vein isolation
- Where
- Germany
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Paroxysmal Atrial Fibrillation, Stroke
Using a Personal Heart Rhythm Monitor to Diagnose Paroxsymal Atrial Fibrillation in the Community
This propsective study aims to compare the diagnostic yield of a Personal Heart Rhythm Monitor (PHRM) with an automated cardiac event recorder (ACER) to detect paroxysmal Atrial Fibrillation PAF).
- Trial name
- NCT01867060
- Testing
- Automated Cardiac Event Recorder, Personal Heart Rhythm Monitor
- Where
- United Kingdom
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- University of Surrey
Atrial Fibrillation, Paroxysmal AF
CARTO® 3 System and Real Time Intracardiac Ultrasound
This is a prospective, multicenter, non-randomized observational study of subjects 18 years and older undergoing RF ablation with drug refractory recurrent symptomatic paroxysmal Atrial Fibrillation (AF).
- Trial name
- IUAF (NCT01716663)
- Testing
- Catheter Ablation
- Where
- 26 sites in United States
- Volunteers
- 234 people, healthy volunteers welcome
- Sponsor
- Biosense Webster, Inc.
Atrial Fibrillation Paroxysmal
The Effect of a Case-finding App on the Detection Rate of Atrial Fibrillation in Primary Care Patients
Atrial fibrillation is a cardiac arrhythmia commonly encountered in a primary care setting. Current screening is limited to pulse palpation and ECG confirmation when an irregular pulse is found.
- Trial name
- NCT04545723
- Testing
- FibriCheck
- Volunteers
- healthy volunteers welcome
- Sponsor
- KU Leuven
Atrial Fibrillation
Paroxysmal Atrial Fibrillation: Role of Inflammation, Oxidative Stress Injury and Effect of Statins
The purpose of this study is to determine the effect of statin therapy for prevention of atrial fibrillation (AF) in pacemaker and non-pacemaker patients with paroxysmal atrial fibrillation in the absence of significant coronary…
- Trial name
- PAFRIOSIES (NCT00321802)
- Testing
- Simvastatin
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Atrial Fibrillation Paroxysmal, Catheter Ablation
Randomized Trial: High Power Short Duration Versus Ablation Index
The single procedure success rates of durable pulmonary vein isolation (PVI) for paroxysmal atrial fibrillation (PAF) varies between 80 and 90 %.
- Trial name
- NCT05251545
- Testing
- Pulmonary vein isolation
- Where
- Germany
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Robert Bosch Medical Center
Atrial Fibrillation
Carvedilol for Prevention of Paroxysmal Atrial Fibrillation
Atrial fibrillation (AF) is the most common sustained heart rhythm disorder and is associated with significant symptoms and health problems including an increased risk of stroke and death.
- Trial name
- NCT01608893
- Testing
- Carvedilol, Metoprolol
- Where
- Canada
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Atrial Fibrillation, Atrial Arrhythmia
Ergospirometry in Paroxysmal Atrial Fibrillation Prognosis
An observational, prospective, cohort study aiming to assess the potential predictive role of cardiopulmonary exercise testing in the prognosis of paroxysmal atrial fibrillation, in combination with echocardiographic indices and…
- Trial name
- PLACEBO (NCT05246423)
- Testing
- Observation group
- Where
- Greece
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Atrial Fibrillation, Atrial Function
Multi-Channel Esophageal ECG Signal Classification
This study is designed to prove new methods to enable the automated analysis of esophageal electrocardiography (eECG) signals in long-term measurements as well as the detection of atrial fibrillation.
- Conditions
- Atrial Fibrillation, Atrial Function, Arrhythmias, Cardiac, Atrial Premature Complexes
- Trial name
- MC-EECG (NCT02541175)
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Atrial Fibrillation (AF), Paroxysmal Atrial Fibrillation (PAF)
Multi-Centre Based Study Recognition of Atrial Fibrillation With the Corsano CardioWatch 287-2 System
This concerns a multi-center, single-arm, diagnostic accuracy study. In this study, a wristband that monitors heart rythm is assessed in clinical and free living conditions.
- Trial name
- COR-AF (NCT06955273)
- Testing
- Corsano CardioWatch 287-2
- Where
- Netherlands
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Corsano Health B.V.